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Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Authors: Liang Chen, Biyun Zhu, Gaomeng Ru, Haowei Meng, Yongchang Yan, Mengjia Hong, Dan Zhang, Changming Luan, Shun Zhang, Hao Wu, Hongyi Gao, Sijia Bai, Changqing Li, Ruoyi Ding, Niannian Xue, Zhixin Lei, Yuting Chen, Yuting Guan, Stefan Siwko, Yiyun Cheng, Gaojie Song, Liren Wang, Chengqi Yi, Mingyao Liu, Dali Li

Journal: Nat Biotechnol

PubMed ID: 36357717

Doi: 10.1038/s41587-022-01532-7

Products & Services: Synthetic Guide RNA

Insights into glycosidic bond specificity of an engineered selective α-L-rhamnosidase N12-Rha via activity assays and molecular modelling

Authors: Bo Yu, Shiyu Luo, Yuhan Ding, Zijie Gong, Ting Nie

Journal: AMB Express

PubMed ID: 36370155

Doi: 10.1186/s13568-022-01489-5

Products & Services: Codon Optimization

A Vaccine of SARS-CoV-2 S Protein RBD Induces Protective Immunity

Authors: Qiaoqiao Qu, Pengfei Hao, Wang Xu, Letian Li, Yuhang Jiang, Zhiqiang Xu, Jing Chen, Zihan Gao, Zhaoxia Pang, Ningyi Jin, Chang Li

Journal: Int J Mol Sci

PubMed ID: 36430190

Doi: 10.3390/ijms232213716

Products & Services: Custom Vector Construction

Fitness Costs of pfhrp2 and pfhrp3 Deletions Underlying Diagnostic Evasion in Malaria Parasites

Authors: Shalini Nair, Xue Li, Standwell C Nkhoma, Tim Anderson

Journal: J Infect Dis

PubMed ID: 35709327

Doi: 10.1093/infdis/jiac240

Products & Services: Plasmid DNA Preparation

Proteomic Landscape and Deduced Functions of the Cardiac 14-3-3 Protein Interactome

Authors: Jia-Hua Qu, Kirill V Tarasov, Khalid Chakir, Yelena S Tarasova, Daniel R Riordon, Edward G Lakatta

Journal: Cells

PubMed ID: 36359893

Doi: 10.3390/cells11213496

Products & Services: Protein and Antibody Isolation

Evaluation of commercially available fully automated and ELISA-based assays for detecting anti-SARS-CoV-2 neutralizing antibodies

Authors: Hadeel T Zedan, Hadi M Yassine, Duaa W Al-Sadeq, Na Liu, Hamda Qotba, Eleonora Nicolai, Massimo Pieri, Sergio Bernardini, Laith J Abu-Raddad, Gheyath K Nasrallah

Journal: Sci Rep

PubMed ID: 36347859

Doi: 10.1038/s41598-022-21317-x

Products & Services: ELISA Kits

Chaperoning activity of the cyclophilin family prevents tau aggregation

Authors: Shannon E Hill , Abigail R Esquivel , Santiago Rodriguez Ospina , Lauren M Rahal , Chad A Dickey , Laura J Blair

Journal: Protein Sci

PubMed ID: 36305768

Doi: 10.1002/pro.4448

Products & Services: PCR Cloning and Subcloning

Structure/function studies on the activation motif of two non-mammalian Mrap1 orthologs, and observations on the phylogeny of Mrap1, including a novel characterization of an Mrap1 from the chondrostean fish, Polyodon spathula.

Authors: Robert M. Dores , Greer McKinley, Audrey Meyers, Morgan Martin and Ciaran A. Shaughnessy

Journal: Biomolecules

Doi: 10.3390/biom12111681

Products & Services: Gene Synthesis

Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes

Authors: Zeyu Jin , Li Wan , Yuqi Zhang , Xuecheng Li , Yong Cao , Haobin Liu , Shengyao Fan , Du Cao , Zhengmao Wang , Xiaobo Li , Junmin Pan , Meng-Qiu Dong , Jianping Wu , Zhen Yan

Journal: Cell

PubMed ID: 36413996

Doi: 10.1016/j.cell.2022.10.030

Products & Services: Protein and Antibody Isolation

Rice FLOURY ENDOSPERM22, encoding a pentatricopeptide repeat protein, is involved in both mitochondrial RNA splicing and editing and is crucial for endosperm development

Authors: Hang Yang , Yunlong Wang , Yunlu Tian , Xuan Teng , Zehui Lv , Jie Lei , Erchao Duan , Hui Dong , Xue Yang , Yuanyan Zhang , Yinglun Sun , Xiaoli Chen , Xiuhao Bao , Rongbo Chen , Chuanwei Gu , Yipeng Zhang , Xiaokang Jiang , Wenyu Ma , Pengcheng Zhang , Yi Ji , Yu Zhang , Yihua Wang , Jianmin Wan

Journal: J Integr Plant Biol

PubMed ID: 36333887

Doi: 10.1111/jipb.13402

Products & Services: Custom DNA/RNA Oligos