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A High-Throughput Search for SFXN1 Physical Partners Led to the Identification of ATAD3, HSD10 and TIM50

Authors: Nesrine Tifoun, Mourad Bekhouche, José M De Las Heras, Arnaud Guillaume, Sylvina Bouleau, Isabelle Guénal, Bernard Mignotte, Nathalie Le Floch

Journal: Biology (Basel)

PubMed ID: 36138777

Doi: 10.3390/biology11091298

Products & Services: Stable Cell Lines

Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease

Authors: Yue Dong, Hanqiao Yu, Xueqi Li, Kelong Bian, Yayuan Zheng, Mingrui Dai, Xuejian Feng, Yao Sun, Yu He, Bin Yu, Haihong Zhang, Jiaxin Wu, Xianghui Yu, Hui Wu, Wei Kong

Journal: J Neuroinflammation

PubMed ID: 35971179

Doi: 10.1186/s12974-022-02567-y

Products & Services: Gene Synthesis

Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms

Authors: Laura J Stevens, Andrea J Pruijssers, Hery W Lee, Calvin J Gordon, Egor P Tchesnokov, Jennifer Gribble, Amelia S George, Tia M Hughes, Xiaotao Lu, Jiani Li, Jason K Perry, Danielle P Porter, Tomas Cihlar, Timothy P Sheahan, Ralph S Baric, Matthias Götte, Mark R Denison

Journal: Sci Transl Med

PubMed ID: 35482820

Doi: 10.1126/scitranslmed.abo0718

Products & Services: Plasmid DNA Preparation

assessment of simultaneous G1 cyclins silencing by a tumor-specific bidirectional promoter on the mammary tumor in nude mice

Authors: Gholamreza Mesbah, Fatemeh Namazi, Fatemeh T Shamsabadi, Zahra Maleki, Mehrab Nasirikenari, Majid Shahbazi

Journal: Front Vet Sci

PubMed ID: 36072388

Doi: 10.3389/fvets.2022.914311

Products & Services: Custom Vector Construction

Translational potential of base-editing tools for gene therapy of monogenic diseases

Authors: Vasiliy V Reshetnikov, Angelina V Chirinskaite, Julia V Sopova, Roman A Ivanov, Elena I Leonova

Journal: Front Bioeng Biotechnol

PubMed ID: 36032737

Doi: 10.3389/fbioe.2022.942440

Products & Services: Codon Optimization

Signal Peptide-rheostat Dynamics Delay Secretory Preprotein Folding

Authors: Dries Smets, Jochem Smit, Ying Xu, Spyridoula Karamanou, Anastassios Economou

Journal: J Mol Biol

PubMed ID: 35970402

Doi: 10.1016/j.jmb.2022.167790

Products & Services: Custom Vector Construction

Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells

Authors: Sjoukje J C van der Stegen, Pieter L Lindenbergh, Roseanna M Petrovic, Hongyao Xie, Mame P Diop, Vera Alexeeva, Yuzhe Shi, Jorge Mansilla-Soto, Mohamad Hamieh, Justin Eyquem, Annalisa Cabriolu, Xiuyan Wang, Ramzey Abujarour, Tom Lee, Raedun Clarke, Bahram Valamehr, Maria Themeli, Isabelle Riviere, Michel Sadelain

Journal: Nat Biomed Eng

PubMed ID: 35941192

Doi: 10.1038/s41551-022-00915-0

Products & Services: PCR Cloning and Subcloning

Quorum Sensing Regulation of a Major Facilitator Superfamily Transporter Affects Multiple Streptococcal Virulence Factors

Authors: Jennifer C Chang, Reid V Wilkening, Kate M Rahbari, Michael J Federle

Journal: J Bacteriol

PubMed ID: 35938850

Doi: 10.1128/jb.00176-22

Products & Services: Catalog Peptides

A computational approach to rapidly design peptides that detect SARS-CoV-2 surface protein S

Authors: Maryam Hajikarimlou, Mohsen Hooshyar, Mohamed Taha Moutaoufik, Khaled A Aly, Taha Azad, Sarah Takallou, Sasi Jagadeesan, Sadhna Phanse, Kamaledin B Said, Bahram Samanfar, John C Bell, Frank Dehne, Mohan Babu, Ashkan Golshani

Journal: NAR Genom Bioinform

PubMed ID: 36004308

Doi: 10.1093/nargab/lqac058

Products & Services: Catalog Antibodies

The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19

Authors: Angela J Rogers, Deborah Wentworth, Andrew Phillips, Katy Shaw-Saliba, Robin L Dewar, Neil R Aggarwal, Abdel G Babiker, Weizhong Chang, Nila J Dharan, Victoria J Davey, Elizabeth S Higgs, Norman Gerry, Adit A Ginde, J W Awori Hayanga, Helene Highbarger, Jeroen L Highbarger, Mamta K Jain, Virginia Kan, Kami Kim, Perrine Lallemand, Bradley G Leshnower, Joseph K Lutaakome, Gail Matthews, Ahmad Mourad, Eleftherios Mylonakis, Ven Natarajan, Maria L Padilla, Lavannya M Pandit, Roger Paredes, Sarah Pett, Srikanth Ramachandruni, M Tauseef Rehman, Brad T Sherman, D Clark Files, Samuel M Brown, Michael A Matthay, B Taylor Thompson, James D Neaton, H Clifford Lane, Jens D Lundgren

Journal: Ann Intern Med

PubMed ID: 36037469

Doi: 10.7326/M22-0924