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A sample-to-answer, quantitative real-time PCR system with low-cost, gravity-driven microfluidic cartridge for rapid detection of SARS-CoV-2, influenza A/B, and human papillomavirus 16/18

Authors: Yunfeng Zai, Chao Min, Zunliang Wang, Yongjun Ding, Huan Zhao, Enben Su, Nongyue He

Journal: Lab Chip

PubMed ID: 35972195

Doi: 10.1039/d2lc00434h

Products & Services: Gene Synthesis

Identification and assessment of TCR-T cells targeting an epitope conserved in SARS-CoV-2 variants for the treatment of COVID-19

Authors: Yipeng Ma , Fenglan Liu , Bin Li , Kaiqi Peng , Hong Zhou , You Xu , Dongjuan Qiao , Lijuan Deng , Geng Tian , Morten Nielsen , Mingjun Wang

Journal: Int Immunopharmacol

PubMed ID: 36201943

Doi: 10.1016/j.intimp.2022.109283

Products & Services: Peptide Synthesis

Exploring the Binding Affinity and Mechanism between ACE2 and the Trimers of Delta and Omicron Spike Proteins by Molecular Dynamics Simulation and Bioassay

Authors: Liping Zhou, Tingting Liu, Mengxia Mo, Yulong Shi, Leyun Wu, Yishui Li, Qiuping Qin, Weiliang Zhu, Chengkun Wu, Likun Gong, Zhijian Xu

Journal: J Chem Inf Model

PubMed ID: 36053674

Doi: 10.1021/acs.jcim.2c00881

Products & Services: Protein and Antibody Isolation

A LILRB1 variant with a decreased ability to phosphorylate SHP-1 leads to autoimmune diseases

Authors: Thivaratana Sinthuwiwat, Supranee Buranapraditkun, Wuttichart Kamolvisit, Siraprapa Tongkobpetch, Wanna Chetruengchai, Chalurmpon Srichomthong, Adjima Assawapitaksakul, Chureerat Phokaew, Patipark Kueanjinda, Tanapat Palaga, Tadech Boonpiyathad, Kanya Suphapeetiporn, Nattiya Hirankarn, Vorasuk Shotelersuk

Journal: Sci Rep

PubMed ID: 36104364

Doi: 10.1038/s41598-022-19334-x

Products & Services: Mutagenesis Services

A Secreted Form of the Hepatitis E Virus ORF2 Protein: Design Strategy, Antigenicity and Immunogenicity

Authors: Zihao Chen, Shaoqi Guo, Guanghui Li, Dong Ying, Guiping Wen, Mujin Fang, Yingbin Wang, Zimin Tang, Zizheng Zheng, Ningshao Xia

Journal: Viruses

PubMed ID: 36298677

Doi: 10.3390/v14102122

Products & Services: ORF cDNA Clones/MolecularCloud

Structural Basis of Substrate Promiscuity and Catalysis by the Reverse Prenyltransferase -Dimethylallyl-l-tryptophan Synthase from

Authors: Samuel A Eaton, Trey A Ronnebaum, Benjamin W Roose, David W Christianson

Journal: Biochemistry

PubMed ID: 36084241

Doi: 10.1021/acs.biochem.2c00350

Products & Services: Custom Vector Construction

Targeting extracellular matrix remodeling sensitizes glioblastoma to ionizing radiation

Authors: Varsha Thakur, Vijay S Thakur, Brittany Aguila, Tatiana I Slepak, Man Wang, Wei Song, Mohini Konai, Shahriar Mobashery, Mayland Chang, Ayush B Rana, Dazhi Wang, Juliano Tiburcio de Freitas, Sakir Humayun Gultekin, Scott M Welford, Michael E Ivan, Barbara Bedogni

Journal: Neurooncol Adv

PubMed ID: 36212741

Doi: 10.1093/noajnl/vdac147

Products & Services: Catalog Peptides

A miniaturized bionic ocean-battery mimicking the structure of marine microbial ecosystems

Authors: Huawei Zhu, Liru Xu, Guodong Luan, Tao Zhan, Zepeng Kang, Chunli Li, Xuefeng Lu, Xueli Zhang, Zhiguang Zhu, Yanping Zhang, Yin Li

Journal: Nat Commun

PubMed ID: 36153325

Doi: 10.1038/s41467-022-33358-x

Products & Services: Codon Optimization

FtlA and FtlB Are Candidates for Inclusion in a Next-Generation Multiantigen Subunit Vaccine for Lyme Disease

Authors: Andrew C Camire, Nathaniel S O'Bier, Dhara T Patel, Nicholas A Cramer, Reinhard K Straubinger, Edward B Breitschwerdt, Rebecca A Funk, Richard T Marconi

Journal: Infect Immun

PubMed ID: 36102656

Doi: 10.1128/iai.00364-22

Products & Services: Codon Optimization

A soybean sodium/hydrogen exchanger GmNHX6 confers plant alkaline salt tolerance by regulating Na/K homeostasis

Authors: Ting Jin, Jiaxin An, Huadong Xu, Jie Chen, Lang Pan, Ranran Zhao, Ning Wang, Junyi Gai, Yan Li

Journal: Front Plant Sci

PubMed ID: 36204047

Doi: 10.3389/fpls.2022.938635

Products & Services: DNA Sequencing