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Engineering B cells with customized therapeutic responses using a synthetic circuit

Authors: Audrey Page, Marie Delles, Didier Nègre, Caroline Costa, Floriane Fusil, François-Loïc Cosset

Journal: Mol Ther Nucleic Acids

PubMed ID: 37359346

Doi: 10.1016/j.omtn.2023.05.024

Products & Services: PCR Cloning and Subcloning

Structural mechanism of intracellular autoregulation of zinc uptake in ZIP transporters

Authors: Changxu Pang, Jin Chai, Ping Zhu, John Shanklin, Qun Liu

Journal: Nat Commun

PubMed ID: 37296139

Doi: 10.1038/s41467-023-39010-6

Products & Services: Gene Synthesis

Scribble mis-localization induces adaptive resistance to KRAS G12C inhibitors through feedback activation of MAPK signaling mediated by YAP-induced MRAS

Authors: Yuta Adachi, Ryo Kimura, Kentaro Hirade, Shogo Yanase, Yuki Nishioka, Natsumi Kasuga, Rui Yamaguchi, Hiromichi Ebi

Journal: Nat Cancer

PubMed ID: 37277529

Doi: 10.1038/s43018-023-00575-2

Products & Services: PCR Cloning and Subcloning

GRT-R910: a self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults

Authors: Christine D Palmer, Ciaran D Scallan, Lauren D Kraemer Tardif, Melissa A Kachura, Amy R Rappaport, Daniel O Koralek, Alison Uriel, Leonid Gitlin, Joshua Klein, Matthew J Davis, Harshni Venkatraman, Meghan G Hart, Jason R Jaroslavsky, Sonia Kounlavouth, Martina Marrali, Charmaine N Nganje, Kyounghwa Bae, Tiffany Yan, Katharyn Leodones, Milana Egorova, Sue-Jean Hong, Jenchun Kuan, Silvia Grappi, Pedro Garbes, Karin Jooss, Andrew Ustianowski

Journal: Nat Commun

PubMed ID: 37280238

Doi: 10.1038/s41467-023-39053-9

Products & Services: Peptide Synthesis

Assessing the Feasibility of Employing a Combination of a Bacteriophage-Derived Endolysin and Spore Germinants to Treat Relapsing Infection

Authors: Khalid Alyahya, Les Baillie

Journal: Microorganisms

PubMed ID: 37512824

Doi: 10.3390/microorganisms11071651

Products & Services: Custom Vector Construction

Expression and characterization of recombinant IL-1Ra in Aspergillus oryzae as a system

Authors: Lena Mahmoudi Azar, Elif Karaman, Burcu Beyaz, Işılay Göktan, Alp Ertunga Eyüpoğlu, Seda Kizilel, Batu Erman, Ahmet Gül, Serdar Uysal

Journal: BMC Biotechnol

PubMed ID: 37340430

Doi: 10.1186/s12896-023-00785-7

Products & Services: Gene Synthesis

Identification of paeoniflorin from Paeonia lactiflora pall As an inhibitor of tryptophan 2,3-dioxygenase and assessment of its pharmacological effects on depressive mice

Authors: Xiaoxia Liang, Ting Su, Pingzhou Wu, Yanting Dai, Yanmin Chen, QiQi Wang, Cheng Cao, Fenglian Chen, Qing Wang, Shuling Wang

Journal: J Ethnopharmacol

PubMed ID: 37315645

Doi: 10.1016/j.jep.2023.116714

Products & Services: Protein and Antibody Isolation

Antibody aggregation can lead to reduced Protein A binding capacity and low step yield

Authors: Gaoya Yuan, Meng Qu, Qi Geng, Wanyuan Dong, Xudong Zhang, Yifeng Li

Journal: Protein Expr Purif

PubMed ID: 37271409

Doi: 10.1016/j.pep.2023.106315

Products & Services: Protein Electrophoresis and Western

Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos

Authors: Liang Chen, Mengjia Hong, Changming Luan, Hongyi Gao, Gaomeng Ru, Xinyuan Guo, Dujuan Zhang, Shun Zhang, Changwei Li, Jun Wu, Peyton B Randolph, Alexander A Sousa, Chao Qu, Yifan Zhu, Yuting Guan, Liren Wang, Mingyao Liu, Bo Feng, Gaojie Song, David R Liu, Dali Li

Journal: Nat Biotechnol

PubMed ID: 37322276

Doi: 10.1038/s41587-023-01821-9

Products & Services: Custom mRNA synthesis Synthetic Guide RNA

Effect of moderate prenatal ethanol exposure on the differential expression of two histamine H3 receptor isoforms in different brain regions of adult rat offspring

Authors: Suzy Davies, Kiana S Lujan, Ella J Rappaport, Carlos F Valenzuela, Daniel D Savage

Journal: Front Neurosci

PubMed ID: 37449267

Doi: 10.3389/fnins.2023.1192096

Products & Services: Protein and Antibody Isolation