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Post-translational control of beige fat biogenesis by PRDM16 stabilization
Authors: Qiang Wang, Huixia Li, Kazuki Tajima, Anthony R P Verkerke, Zachary H Taxin, Zhishuai Hou, Joanne B Cole, Fei Li, Jake Wong, Ichitaro Abe, Rachana N Pradhan, Tadashi Yamamuro, Takeshi Yoneshiro, Joel N Hirschhorn, Shingo Kajimura
Journal: Nature
PubMed ID: 35978186
Doi: 10.1038/s41586-022-05067-4
Products & Services: Custom DNA/RNA Oligos   
Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors
Authors: Sanghyun P Kim, Nolan R Vale, Nikolaos Zacharakis, Sri Krishna, Zhiya Yu, Billel Gasmi, Jared J Gartner, Sivasish Sindiri, Parisa Malekzadeh, Drew C Deniger, Frank J Lowery, Maria R Parkhurst, Lien T Ngo, Satyajit Ray, Yong F Li, Victoria Hill, Maria Florentin, Robert V Masi, Biman C Paria, Noam Levin, Alakesh Bera, Elizabeth A Hedges, Agnes Choi, Praveen D Chatani, Anup Y Parikh, Shoshana Levi, Samantha Seitter, Yong-Chen Lu, Zhili Zheng, Todd D Prickett, Li Jia, Jonathan M Hernandez, Chuong D Hoang, Paul F Robbins, Stephanie L Goff, Richard M Sherry, James C Yang, Steven A Rosenberg
Journal: Cancer Immunol Res
PubMed ID: 35749374
Doi: 10.1158/2326-6066.CIR-22-0040
Products & Services: Peptide Synthesis   
Systematic mutagenesis of TFIIH subunit p52/Tfb2 identifies residues required for XPB/Ssl2 subunit function and genetic interactions with TFB6
Authors: Jacob Bassett, Jenna K Rimel, Shrabani Basu, Pratik Basnet, Jie Luo, Krysta L Engel, Michael Nagel, Alexander Woyciehowsky, Christopher C Ebmeier, Craig D Kaplan, Dylan J Taatjes, Jeffrey A Ranish
Journal: J Biol Chem
PubMed ID: 36041630
Doi: 10.1016/j.jbc.2022.102433
Products & Services: Mutant Libraries   
Enhanced immunogenicity of a positively supercharged archaeon thioredoxin scaffold as a cell-penetrating antigen carrier for peptide vaccines
Authors: Davide Cavazzini, Gloria Spagnoli, Filipe Colaco Mariz, Filippo Reggiani, Stefano Maggi, Valentina Franceschi, Gaetano Donofrio, Martin Müller, Angelo Bolchi, Simone Ottonello
Journal: Front Immunol
PubMed ID: 36032169
Doi: 10.3389/fimmu.2022.958123
Products & Services: Catalog Peptides   
Disruption of nuclear envelope integrity as a possible initiating event in tauopathies
Authors: Marine Prissette, Wen Fury, Matthew Koss, Claudia Racioppi, Daria Fedorova, Ella Dragileva, Georgia Clarke, Taylor Pohl, John Dugan, Diana Ahrens, Joyce Chiu, Charleen Hunt, Chia-Jen Siao, Tara Young, Arijit Bhowmick, Vitaliy Rogulin, Mathieu Desclaux, Eric Y Hayden, Michael Podgorski, Min Gao, Lynn E Macdonald, David Frendewey, George D Yancopoulos, Brian Zambrowicz
Journal: Cell Rep
PubMed ID: 36001963
Doi: 10.1016/j.celrep.2022.111249
Products & Services: Synthetic sgRNA and crRNA Service   
Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System
Authors: Timothy A Klein, Dirk W Grebenc, Prakhar Y Shah, Owen D McArthur, Brandon H Dickson, Michael G Surette, Youngchang Kim, John C Whitney
Journal: MBio
PubMed ID: 36036513
Doi: 10.1128/mbio.02137-22
Products & Services: Polyclonal Antibody Services   
Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells
Authors: Celia Martín-Otal, Aritz Lasarte-Cia, Diego Serrano, Noelia Casares, Enrique Conde, Flor Navarro, Inés Sánchez-Moreno, Marta Gorraiz, Patricia Sarrión, Alfonso Calvo, Carlos E De Andrea, José Echeveste, Amaia Vilas, Juan Roberto Rodriguez-Madoz, Jesús San Miguel, Felipe Prosper, Sandra Hervas-Stubbs, Juan Jose Lasarte, Teresa Lozano
Journal: J Immunother Cancer
PubMed ID: 35918123
Doi: 10.1136/jitc-2021-004479
Products & Services: Plasmid DNA Preparation   
USP29 Deubiquitinates SETD8 and Regulates DNA Damage-Induced H4K20 Monomethylation and 53BP1 Focus Formation
Authors: Yeray Hernández-Reyes, María Cristina Paz-Cabrera, Raimundo Freire, Veronique A J Smits
Journal: Cells
PubMed ID: 36010569
Doi: 10.3390/cells11162492
Products & Services: Proteins, Expression, Isolation and Analysis   
Mechanistic insights into global suppressors of protein folding defects
Authors: Gopinath Chattopadhyay, Jayantika Bhowmick, Kavyashree Manjunath, Shahbaz Ahmed, Parveen Goyal, Raghavan Varadarajan
Journal: PLoS Genet
PubMed ID: 36037221
Doi: 10.1371/journal.pgen.1010334
Products & Services: Proteins, Expression, Isolation and Analysis   
Refolding and characterization of a diabody against Pfs25, a vaccine candidate of Plasmodium falciparum
Authors: Deepak K Jagannath, Ashwathi Valiyaparambil, Vysakh K Viswanath, Manjunath A Hurakadli, Neelagandan Kamariah, Alifia C Jafer, Chhaya Patole, Sabyasachi Pradhan, Naveen Kumar, Anirudha Lakshminarasimhan
Journal: Anal Biochem
PubMed ID: 35944694
Doi: 10.1016/j.ab.2022.114830
Products & Services: PCR Cloning and Subcloning   

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