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A Physiologically Responsive Nanocomposite Hydrogel for Treatment of Head and Neck Squamous Cell Carcinoma via Proteolysis-Targeting Chimeras Enhanced Immunotherapy

Authors: Yaping Wu, Xiaowei Chang, Guizhu Yang, Li Chen, Qi Wu, Jiamin Gao, Ran Tian, Wenyun Mu, John Justin Gooding, Xin Chen, Shuyang Sun

Journal: Adv Mater

PubMed ID: 36656993

Doi: 10.1002/adma.202210787

Products & Services: Peptide Synthesis

Revealing the role of tunable amino acid residues in elastin-like polypeptides (ELPs)-mediated biomimetic silicification

Authors: Yue Qiu , Yuanqing Lin , Bo Zeng , Peiliang Qin , Zhiwei Yi , Guangya Zhang

Journal: Int J Biol Macromol

PubMed ID: 36539170

Doi: 10.1016/j.ijbiomac.2022.12.152

Products & Services: Gene Synthesis

Microenvironment-responsive anti-PD-L1 × CD3 bispecific T-cell engager for solid tumor immunotherapy

Authors: Dingkang Liu, Lichen Bao, Haichao Zhu, Yali Yue, Jing Tian, Xiangdong Gao, Jun Yin

Journal: Journal of controlled release

PubMed ID: 36669532

Doi: 10.1016/j.jconrel.2023.01.041

Products & Services: ELISA Kits

Heteromultivalent scaffolds fabricated by biomimetic co-assembly of DNA-RNA building blocks for the multi-analysis of miRNAs

Authors: Chengjie Duan, Yan Chen, Zhiqiang Hou, Dayong Li, Jin Jiao, Weihao Sun, Yang Xiang

Journal: J Mater Chem B

PubMed ID: 36723144

Doi: 10.1039/d2tb02663e

Products & Services: Protein and Antibody Isolation

Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres

Authors: Radka Storchova, Matous Palek, Natalie Palkova, Pavel Veverka, Tomas Brom, Ctirad Hofr, Libor Macurek

Journal: Nucleic Acids Res

PubMed ID: 36651296

Doi: 10.1093/nar/gkac1269

Products & Services: Peptide Synthesis

Crystallographic data of an importin-α3 dimer in which the two protomers are bridged by a bipartite nuclear localization signal

Authors:

Journal: Data Brief

PubMed ID: 36875212

Doi: 10.1016/j.dib.2023.108988

Products & Services: Protein and Antibody Isolation

Stress-induced plasticity of a CRH/GABA projection disrupts reward behaviors in mice

Authors: Matthew T Birnie, Annabel K Short, Gregory B de Carvalho, Lara Taniguchi, Benjamin G Gunn, Aidan L Pham, Christy A Itoga, Xiangmin Xu, Lulu Y Chen, Stephen V Mahler, Yuncai Chen, Tallie Z Baram

Journal: Nat Commun

PubMed ID: 36841826

Doi: 10.1038/s41467-023-36780-x

Products & Services: Protein and Antibody Isolation

Chikungunya Virus and Its Envelope Protein E2 Induce Hyperalgesia in Mice: Inhibition by Anti-E2 Monoclonal Antibodies and by Targeting TRPV1

Authors: Carina Z Segato-Vendrameto, Camila Zanluca, Amanda Z Zucoloto, Tiago H Zaninelli, Mariana M Bertozzi, Telma Saraiva-Santos, Camila R Ferraz, Larissa Staurengo-Ferrari, Stephanie Badaro-Garcia, Marília F Manchope, Amanda M Dionisio, Felipe A Pinho-Ribeiro, Sergio M Borghi, Ana Luiza Pamplona Mosimann, Rubia Casagrande, Juliano Bordignon, Victor Fattori, Claudia N Duarte Dos Santos, Waldiceu A Verri

Journal: Cells

PubMed ID: 36831223

Doi: 10.3390/cells12040556

Products & Services: Codon Optimization

Selective excitation with recoupling pulse schemes uncover properties of disordered mineral phases in bone-like apatite grown with bone proteins

Authors: Irina Matlahov, Alexey Kulpanovich, Taly Iline-Vul, Merav Nadav-Tsubery, Gil Goobes

Journal: Solid State Nucl Magn Reson

PubMed ID: 36913847

Doi: 10.1016/j.ssnmr.2023.101860

Products & Services: Protein and Antibody Isolation

Suppression of Tumor or Host Intrinsic CMTM6 Drives Antitumor Cytotoxicity in a PD-L1–Independent Manner

Authors: Yiru Long , Runqiu Chen , Xiaolu Yu , Yongliang Tong , Xionghua Peng , Fanglin Li , Chao Hu, Jianhua Sun , Likun Gong

Journal: Cancer Immunol Res .

PubMed ID: 36484740

Doi: 10.1158/2326-6066.CIR-22-0439

Products & Services: Recombinant Proteins