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The NAC transcription factor ONAC083 negatively regulates rice immunity against Magnaporthe oryzae by directly activating transcription of the RING‐H2 gene OsRFPH2‐6

Authors: Yan Bi , Hui Wang , Xi Yuan , Yuqing Yan , Dayong Li , Fengming Song

Journal: J Integr Plant Biol

PubMed ID: 36308720

Doi: 10.1111/jipb.13399

Products & Services: Protein and Antibody Isolation

Improving adenine and dual base editors through introduction of TadA-8e and Rad51DBD

Authors: Niannian Xue, Xu Liu, Dan Zhang, Youming Wu, Yi Zhong, Jinxin Wang, Wenjing Fan, Haixia Jiang, Biyun Zhu, Xiyu Ge, Rachel V L Gonzalez, Liang Chen, Shun Zhang, Peilu She, Zhilin Zhong, Jianjian Sun, Xi Chen, Liren Wang, Zhimin Gu, Ping Zhu, Mingyao Liu, Dali Li, Tao P Zhong, Xiaohui Zhang

Journal: Nat Commun

PubMed ID: 36869044

Doi: 10.1038/s41467-023-36887-1

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Characterization and utility of two monoclonal antibodies to cholera toxin B subunit

Authors: Noel Verjan Garcia, Ian Carlosalberto Santisteban Celis, Matthew Dent, Nobuyuki Matoba

Journal: Sci Rep

PubMed ID: 36922604

Doi: 10.1038/s41598-023-30834-2

Products & Services: Protein and Antibody Isolation

Increasing lysergic acid levels for ergot alkaloid biosynthesis: Directing catalysis the F-G loop of Clavine oxidases

Authors: Li Rong Lim, Garrett Wong, Maybelle K Go, Wen Shan Yew

Journal: Front Microbiol

PubMed ID: 37007471

Doi: 10.3389/fmicb.2023.1150937

Products & Services: Protein and Antibody Isolation

Structural basis for enzymatic terminal C-H bond functionalization of alkanes

Authors: Jin Chai, Gongrui Guo, Sean M McSweeney, John Shanklin, Qun Liu

Journal: Nat Struct Mol Biol

PubMed ID: 36997762

Doi: 10.1038/s41594-023-00958-0

Products & Services: Protein and Antibody Isolation

Effect of preliminary stresses on the induction of viable but non-culturable Escherichia coli O157:H7 NCTC 12900 and Staphylococcus aureus ATCC 6538

Authors: Dong Yang, Liang Zhao, Lei Rao, Xiaojun Liao

Journal: Food Res Int

PubMed ID: 37087272

Doi: 10.1016/j.foodres.2023.112710

Products & Services: Protein and Antibody Isolation

Combination of mathematics and label-free proteomics for discovering keratin-derived specific peptide biomarkers to distinguish animal horn-derived traditional Chinese medicines

Authors: Rui Liu, Jiayao Tang, Wenxing Wu, Jingjing Zhao, Zhaoying Zhu, Hai-Ou Gu, Zhibin Wang, Ming Zhao, Jin-Ao Duan

Journal: J Sep Sci

PubMed ID: 36821105

Doi: 10.1002/jssc.202200949

Products & Services: Protein and Antibody Isolation

DNA sensing via the cGAS/STING pathway activates the immunoproteasome and adaptive T-cell immunity

Authors: Xinyuan Wang, Huabin Zhang, Yuqin Wang, Laylan Bramasole, Kai Guo, Fatima Mourtada, Thomas Meul, Qianjiang Hu, Valeria Viteri, Ilona Kammerl, Melanie Konigshoff, Mareike Lehmann, Thomas Magg, Fabian Hauck, Isis E Fernandez, Silke Meiners

Journal: EMBO J

PubMed ID: 36912165

Doi: 10.15252/embj.2022110597

Products & Services: Peptide Synthesis

Heterologous prime-boost immunisation with mRNAand AdC68-based 2019-nCoV variant vaccines induces broad-spectrum immune responses in mice

Authors: Xingxing Li, Jingjing Liu, Wenjuan Li, Qinhua Peng, Miao Li, Zhifang Ying, Zelun Zhang, Xinyu Liu, Xiaohong Wu, Danhua Zhao, Lihong Yang, Shouchun Cao, Yanqiu Huang, Leitai Shi, Hongshan Xu, Yunpeng Wang, Guangzhi Yue, Yue Suo, Jianhui Nie, Weijin Huang, Jia Li, Yuhua Li

Journal: Frontiers in Immunology

PubMed ID: 37006275

Doi: 10.3389/fimmu.2023.1142394

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Using low-cost disposable immunosensor based on flexible PET screen-printed electrode modified with carbon black and gold nanoparticles for sensitive detection of SARS-CoV-2

Authors: Luís M C Ferreira, Isabela F Reis, Paulo R Martins, Luiz H Marcolino-Junior, Marcio F Bergamini, Jessica R Camargo, Bruno C Janegitz, Fernando C Vicentini

Journal: Talanta Open

PubMed ID: 36959870

Doi: 10.1016/j.talo.2023.100201

Products & Services: Molecular Biology Reagents

Ex Vivo Immune Responsiveness to SARS-CoV-2 Omicron BA51 Following Vaccination with Unmodified mRNA-Vaccine

Authors: Anna Sabrina Kuechler, Eva Heger, Maike Wirtz, Sandra Weinhold, Markus Uhrberg, Fritz Boege, Karin Schulze-Bosse

Journal: Vaccines (Basel)

PubMed ID: 36992182

Doi: 10.3390/vaccines11030598

Products & Services: Molecular Biology Reagents

In vivo imaging of calcium dynamics in zebrafish hepatocytes

Authors: Macarena Pozo-Morales, Inés Garteizgogeascoa, Camille Perazzolo, Juhoon So, Donghun Shin, Sumeet Pal Singh

Journal: Hepatology

PubMed ID: 35829917

Doi: 10.1002/hep.32663

Products & Services: Gene Synthesis

Preclinical evaluation of immunogenicity, efficacy and safety of a recombinant plant-based SARS-CoV-2 RBD vaccine formulated with 3M-052-Alum adjuvant

Authors: Waranyoo Phoolcharoen, Balamurugan Shanmugaraj, Narach Khorattanakulchai, Piyanate Sunyakumthorn, Sathit Pichyangkul, Pornnarin Taepavarapruk, Wanlapa Praserthsee, Suchinda Malaivijitnond, Suwimon Manopwisedjaroen, Arunee Thitithanyanont, Kanjana Srisutthisamphan, Anan Jongkaewwattana, Mark Tomai, Christopher B Fox, Suthira Taychakhoonavudh

Journal: Vaccine

PubMed ID: 36963999

Doi: 10.1016/j.vaccine.2023.03.027

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Phase I Trial of a Therapeutic DNA Vaccine for Preventing Hepatocellular Carcinoma from Chronic Hepatitis C Virus (HCV) Infection

Authors: Jeffrey M Jacobson, David Zahrieh, Carrie A Strand, Marcia Cruz-Correa, Surakit Pungpapong, Lewis R Roberts, Sumithra J Mandrekar, Luz Maria Rodriguez, Jean Boyer, Idania Marrero, Kimberly A Kraynyak, Matthew P Morrow, Albert J Sylvester, Jan M Pawlicki, Elisabeth Gillespie, Eduardo Barranco, Ellen Richmond, Asad Umar, David B Weiner, Paul J Limburg

Journal: Cancer Prev Res (Phila)

PubMed ID: 36534786

Doi: 10.1158/1940-6207.CAPR-22-0217

Products & Services: Peptide Synthesis

Bispecific antibodies combine breadth, potency, and avidity of parental antibodies to neutralize sarbecoviruses

Authors: Laura Radić, Kwinten Sliepen, Victor Yin, Mitch Brinkkemper, Joan Capella-Pujol, Angela I Schriek, Jonathan L Torres, Sandhya Bangaru, Judith A Burger, Meliawati Poniman, Ilja Bontjer, Joey H Bouhuijs, David Gideonse, Dirk Eggink, Andrew B Ward, Albert J R Heck, Marit J Van Gils, Rogier W Sanders, Janke Schinkel

Journal: iScience

PubMed ID: 37063468

Doi: 10.1016/j.isci.2023.106540

Products & Services: Recombinant Proteins

Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates

Authors: Yvonne J Rosenberg, Tracy Ordonez, Urjeet S Khanwalkar, Philip Barnette, Shilpi Pandey, Iara M Backes, Claire E Otero, Benjamin S Goldberg, Andrew R Crowley, David A Leib, Mariya B Shapiro, Xiaoming Jiang, Lori A Urban, Jonathan Lees, Ann J Hessell, Sallie Permar, Nancy L Haigwood, Margaret E Ackerman

Journal: MBio

PubMed ID: 36946726

Doi: 10.1128/mbio.00341-23

Products & Services: Recombinant Proteins

Structural basis of Janus kinase trans-activation

Authors: Nathanael A Caveney, Robert A Saxton, Deepa Waghray, Caleb R Glassman, Naotaka Tsutsumi, Stevan R Hubbard, K Christopher Garcia

Journal: Cell Rep

PubMed ID: 36867534

Doi: 10.1016/j.celrep.2023.112201

Products & Services: Protein and Antibody Isolation

Cloning, characterization, and heterologous expression of a candidate Hirudin gene from the salivary gland transcriptome of Hirudo nipponia

Authors: Ping Shi, Jian Wei, Huajian You, Shijiang Chen, Fayin Tan, Zenghui Lu

Journal: Sci Rep

PubMed ID: 36973525

Doi: 10.1038/s41598-023-32303-2

Products & Services: Protein and Antibody Isolation

Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train

Authors: Yuanyuan Ma, Jun He, Shaobai Li, Deqiang Yao, Chenhui Huang, Jian Wu, Ming Lei

Journal: Nat Commun

PubMed ID: 36932088

Doi: 10.1038/s41467-023-37208-2

Products & Services: Protein and Antibody Isolation

DAB2IP-knocking down resulted in radio-resistance of breast cancer cells is associated with increased hypoxia and vasculogenic mimicry formation

Authors: Xiangyan Zhang, Quanxin Wang, Ruiqi Zhang, Zhaolu Kong

Journal: Int J Radiat Biol

PubMed ID: 36947637

Doi: 10.1080/09553002.2023.2194390

Products & Services: Protein and Antibody Isolation

Regulation of neurofilament length and transport by a dynamic cycle of phospho-dependent polymer severing and annealing

Authors: Atsuko Uchida, Juan Peng, Anthony Brown

Journal: Mol Biol Cell

PubMed ID: 36989035

Doi: 10.1091/mbc.E23-01-0024

Products & Services: Gene Synthesis

Exposure to diverse sarbecoviruses indicates frequent zoonotic spillover in human communities interacting with wildlife

Authors: Tierra Smiley Evans, Chee Wah Tan, Ohnmar Aung, Sabai Phyu, Htin Lin, Lark L Coffey, Aung Than Toe, Pyaephyo Aung, Tin Htun Aung, Nyein Thu Aung, Christopher M Weiss, Kyaw Zin Thant, Zaw Than Htun, Suzan Murray, Linfa Wang, Christine Kreuder Johnson, Hlaing Myat Thu

Journal: Int J Infect Dis

PubMed ID: 36870470

Doi: 10.1016/j.ijid.2023.02.015

Products & Services: Molecular Biology Reagents

CDetectionv2: One-pot assay for the detection of SARS-CoV-2

Authors: Xinge Wang, Yangcan Chen, Xuejia Cheng, Si-Qi Wang, Yanping Hu, Yingmei Feng, Ronghua Jin, Kangping Zhou, Ti Liu, Jianxing Wang, Kai Pan, Bing Liu, Jie Xiang, Yanping Wang, Qi Zhou, Ying Zhang, Weiye Pan, Wei Li

Journal: Front Microbiol

PubMed ID: 37032875

Doi: 10.3389/fmicb.2023.1158163

Products & Services: Molecular Biology Reagents

Integrating biopolymer design with physical unclonable functions for anticounterfeiting and product traceability in agriculture

Authors: Hui Sun, Saurav Maji, Anantha P Chandrakasan, Benedetto Marelli

Journal: Sci Adv

PubMed ID: 36947609

Doi: 10.1126/sciadv.adf1978

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Epigenetic immune monitoring for COVID-19 disease course prognosis

Authors: Björn Samans, Marta Rosselló Chornet, Araceli Rosselló Chornet, Janine Jung, Konstantin Schildknecht, Laura Lozza, Lourdes Alos Zaragoza, Javier Hernández Laforet, Nina Babel, Sven Olek

Journal: Front Immunol

PubMed ID: 36999021

Doi: 10.3389/fimmu.2023.1107900

Products & Services: Molecular Biology Reagents

A Putative Receptor for Ferritin in Mollusks: Characterization of the Insulin-like Growth Factor Type 1 Receptor

Authors: Bowen Huang, Qin Liu, Changming Bai, Chen Li, Chongming Wang, Lusheng Xin

Journal: Int J Mol Sci

PubMed ID: 37047145

Doi: 10.3390/ijms24076175

Products & Services: Protein and Antibody Isolation

Sniper2L is a high-fidelity Cas9 variant with high activity

Authors: Young-Hoon Kim, Nahye Kim, Ikenna Okafor, Sungchul Choi, Seonwoo Min, Joonsun Lee, Seung-Min Bae, Keunwoo Choi, Janice Choi, Vinayak Harihar, Youngho Kim, Jin-Soo Kim, Benjamin P Kleinstiver, Jungjoon K Lee, Taekjip Ha, Hyongbum Henry Kim

Journal: Nat Chem Biol

PubMed ID: 36894722

Doi: 10.1038/s41589-023-01279-5

Products & Services: Protein and Antibody Isolation

Evaluation and deployment of isotype-specific salivary antibody assays for detecting previous SARS-CoV-2 infection in children and adults

Authors: Amy C Thomas, Elizabeth Oliver, Holly E Baum, Kapil Gupta, Kathryn L Shelley, Anna E Long, Hayley E Jones, Joyce Smith, Benjamin Hitchings, Natalie di Bartolo, Kate Vasileiou, Fruzsina Rabi, Hanin Alamir, Malak Eghleilib, Ore Francis, Jennifer Oliver, Begonia Morales-Aza, Ulrike Obst, Debbie Shattock, Rachael Barr, Lucy Collingwood, Kaltun Duale, Niall Grace, Guillaume Gonnage Livera, Lindsay Bishop, Harriet Downing, Fernanda Rodrigues, Nicholas Timpson, Caroline L Relton, Ashley Toye, Derek N Woolfson, Imre Berger, Anu Goenka, Andrew D Davidson, Kathleen M Gillespie, Alistair J K Williams, Mick Bailey, Ellen Brooks-Pollock, Adam Finn, Alice Halliday

Journal: Commun Med (Lond)

PubMed ID: 36922542

Doi: 10.1038/s43856-023-00264-2

Products & Services: Protein and Antibody Isolation

Process development and characterization of recombinant nucleocapsid protein for its application on COVID-19 diagnosis

Authors: Luãnna Elisa Liebscher Vidal, Janaina Figueira-Mansur, Patrícia Barbosa Jurgilas, Ana Paula Correa Argondizzo, Cristiane Pinheiro Pestana, Fernanda Otaviano Martins, Haroldo Cid da Silva Junior, Mariana Miguez, Bernardo Oliveira Loureiro, Christiane de Fátima Silva Marques, Karen Soares Trinta, Leila Botelho Rodrigues da Silva, Marcelle Bral de Mello, Edimilson Domingos da Silva, Renata Chagas Bastos, Gabriela Esteves

Journal: Protein Expr Purif

PubMed ID: 36921810

Doi: 10.1016/j.pep.2023.106263

Products & Services: Molecular Biology Reagents

Arc ubiquitination regulates endoplasmic reticulum-mediated Ca release and CaMKII signaling

Authors: Mohammad A Ghane, Wei Wei, Dina W Yakout, Zachary D Allen, Cassandra L Miller, Bin Dong, Jenny J Yang, Ning Fang, Angela M Mabb

Journal: Front Cell Neurosci

PubMed ID: 36998269

Doi: 10.3389/fncel.2023.1091324

Products & Services: Protein and Antibody Isolation

JNK Activation in Alzheimer's Disease Is Driven by Amyloid β and Is Associated with Tau Pathology

Authors: Maite Solas, Silvia Vela, Cristian Smerdou, Eva Martisova, Iván Martínez-Valbuena, María-Rosario Luquin, María J Ramírez

Journal: ACS Chem Neurosci

PubMed ID: 36976903

Doi: 10.1021/acschemneuro.3c00093

Products & Services: Protein and Antibody Isolation

The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function

Authors: Tineke Vanderhaeghen, Steven Timmermans, Melanie Eggermont, Deepika Watts, Jolien Vandewalle, Charlotte Wallaeys, Louise Nuyttens, Joyca De Temmerman, Tino Hochepied, Sylviane Dewaele, Joke Vanden Berghe, Niek Sanders, Ben Wielockx, Rudi Beyaert, Claude Libert

Journal: Front Immunol

PubMed ID: 37006237

Doi: 10.3389/fimmu.2023.1124011

Products & Services: Protein and Antibody Isolation

Trends in the evolution of the elasmobranch melanocortin-2 receptor: Insights from structure/function studies on the activation of whale shark Mc2r

Authors: Brianne E Hoglin, Marin V Miner, Ugumuur Erbenebayar, Ciaran A Shaughnessy, Robert M Dores

Journal: Gen Comp Endocrinol

PubMed ID: 36996927

Doi: 10.1016/j.ygcen.2023.114278

Products & Services: Protein and Antibody Isolation

IL-10-providing B cells govern pro-inflammatory activity of macrophages and microglia in CNS autoimmunity

Authors: Anastasia Geladaris, Silke Häusser-Kinzel, Roxanne Pretzsch, Nitzan Nissimov, Klaus Lehmann-Horn, Darius Häusler, Martin S Weber

Journal: Acta Neuropathol

PubMed ID: 36854993

Doi: 10.1007/s00401-023-02552-6

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IGFBP‑rP1 affects the proliferation, apoptosis and macrophage polarization of endometrial cancer cells by regulating the PI3K/AKT pathway

Authors: Juan Gao, Shiqi Suo, Jingxia Li, Chunxia Wang, Ranran Deng, Yuxia Hu, Chunzheng Zhang

Journal: Exp Ther Med

PubMed ID: 37006880

Doi: 10.3892/etm.2023.11868

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miR-126 mitigates the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting the ERK1/2 and Bcl-2 pathways

Authors: Ying Zhang, Yiping Dong, Qiushi Wei, Zhikun Zhuang, Youwen Liu, Qiang Yuan, Wei He, Zhenhao Jing, Jitian Li, Peifeng Li, Leilei Zhang, Zhinan Hong, Ning Zhang, Haibin Wang, Wuyin Li

Journal: Acta Biochim Biophys Sin (Shanghai)

PubMed ID: 36942990

Doi: 10.3724/abbs.2023016

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The proprotein convertase SKI-1/S1P is a critical host factor for Nairobi sheep disease virus infectivity

Authors: Caroline Bost, Julia Hartlaub, Vinícius Pinho Dos Reis, Thomas Strecker, Nabil G Seidah, Martin H Groschup, Sandra Diederich, Kerstin Fischer

Journal: Virus Res

PubMed ID: 36948228

Doi: 10.1016/j.virusres.2023.199099

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Rare Catechol--methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets

Authors: Fia B Larsen, Matteo Cagiada, Jonas Dideriksen, Amelie Stein, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

Journal: Biochemistry

PubMed ID: 36976271

Doi: 10.1021/acs.biochem.3c00008

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Relative role of border restrictions, case finding and contact tracing in controlling SARS-CoV-2 in the presence of undetected transmission: a mathematical modelling study

Authors: Rachael Pung, Hannah E Clapham, Timothy W Russell, Vernon J Lee, Adam J Kucharski

Journal: BMC Med

PubMed ID: 36927576

Doi: 10.1186/s12916-023-02802-0

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JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial hypertension

Authors: Chen Zhang, Yue Sun, Yingying Guo, Jingjing Xu, Haiyan Zhao

Journal: Cell Death Discov

PubMed ID: 36934091

Doi: 10.1038/s41420-023-01390-5

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Nuclease activity of Plasmodium falciparum Alba family protein PfAlba3

Authors: Chinmoy Banerjee, Shiladitya Nag, Manish Goyal, Debanjan Saha, Asim Azhar Siddiqui, Somnath Mazumder, Subhashis Debsharma, Saikat Pramanik, Uday Bandyopadhyay

Journal: Cell Rep

PubMed ID: 36947546

Doi: 10.1016/j.celrep.2023.112292

Anti-human immunodeficiency virus-1 activity of MoMo30 protein isolated from the traditional African medicinal plant Momordica balsamina

Authors: Mahfuz Khan, Amad Diop, Erick Gbodossou, Peng Xiao, Morgan Coleman, Kenya De Barros, Hao Duong, Vincent C Bond, Virginia Floyd, Kofi Kondwani, Valerie Montgomery Rice, Sandra Harris-Hooker, Francois Villinger, Michael D Powell

Journal: Virol J

PubMed ID: 36949470

Doi: 10.1186/s12985-023-02010-5

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Identification of tagged glycans with a protein nanopore

Authors: Minmin Li, Yuting Xiong, Yuchen Cao, Chen Zhang, Yuting Li, Hanwen Ning, Fan Liu, Han Zhou, Xiaonong Li, Xianlong Ye, Yue Pang, Jiaming Zhang, Xinmiao Liang, Guangyan Qing

Journal: Nat Commun

PubMed ID: 36977665

Doi: 10.1038/s41467-023-37348-5

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Programmable protein delivery with a bacterial contractile injection system

Authors: Joseph Kreitz, Mirco J Friedrich, Akash Guru, Blake Lash, Makoto Saito, Rhiannon K Macrae, Feng Zhang

Journal: Nature

PubMed ID: 36991127

Doi: 10.1038/s41586-023-05870-7

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Conservation and divergence of flg22, pep1 and nlp20 in activation of immune response and inhibition of root development

Authors: Yan Huang, Junmei Cui, Meng Li, Rongqian Yang, Yang Hu, Xiaosong Yu, Ying Chen, Qiqi Wu, Huipeng Yao, Guozhi Yu, Jinya Guo, Huaiyu Zhang, Shuang Wu, Yi Cai

Journal: Plant Sci

PubMed ID: 36963637

Doi: 10.1016/j.plantsci.2023.111686

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The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma

Authors: Lucia Morgado-Palacin, Jessie A Brown, Thomas F Martinez, Juana M Garcia-Pedrero, Farhad Forouhar, S Aidan Quinn, Clara Reglero, Joan Vaughan, Yasamin Hajy Heydary, Cynthia Donaldson, Sandra Rodriguez-Perales, Eva Allonca, Rocio Granda-Diaz, Agustin F Fernandez, Mario F Fraga, Arianna L Kim, Jorge Santos-Juanes, David M Owens, Juan P Rodrigo, Alan Saghatelian, Adolfo A Ferrando

Journal: Nat Commun

PubMed ID: 36899004

Doi: 10.1038/s41467-023-36713-8

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Structural basis of peptide recognition and activation of endothelin receptors

Authors: Yujie Ji, Jia Duan, Qingning Yuan, Xinheng He, Gong Yang, Shengnan Zhu, Kai Wu, Wen Hu, Tianyu Gao, Xi Cheng, Hualiang Jiang, H Eric Xu, Yi Jiang

Journal: Nat Commun

PubMed ID: 36882417

Doi: 10.1038/s41467-023-36998-9

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Cytokinin-responsive MdTCP17 interacts with MdWOX11 to repress adventitious root primordium formation in apple rootstocks

Authors: Jiangping Mao, Chundong Niu, Ke Li, Li Fan, Zhimin Liu, Shaohuan Li, Doudou Ma, Muhammad Mobeen Tahir, Libo Xing, Caiping Zhao, Juanjuan Ma, Na An, Mingyu Han, Xiaolin Ren, Dong Zhang

Journal: Plant Cell

PubMed ID: 36544357

Doi: 10.1093/plcell/koac369

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Colorectal cancer-derived extracellular vesicles containing HSP70 enhance macrophage phagocytosis by up-regulating MARCO expression

Authors: Yu Sun, Wenjun Xiao, Yang Yu, Yuchen Jiang, Zhijie Xiao, Defa Huang, Tianyu Zhong, Jiang Li, Xi Xiang, Yulong He, Zhigang Li

Journal: Exp Cell Res

PubMed ID: 36958650

Doi: 10.1016/j.yexcr.2023.113565

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Development of an efficient method for selection of stable cell pools for protein expression and surface display with Expi293F cells

Authors: Chuan Chen, Zening Wang, Zehua Sun, Wei Li, Dimiter S Dimitrov

Journal: Cell Biochem Funct

PubMed ID: 36864545

Doi: 10.1002/cbf.3787

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Uman-type neurofilament light antibodies are effective reagents for the imaging of neurodegeneration

Authors: Gerry Shaw, Irina Madorsky, Ying Li, YongSheng Wang, Marda Jorgensen, Sabhya Rana, David D Fuller

Journal: Brain Commun

PubMed ID: 37091583

Doi: 10.1093/braincomms/fcad067

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Silmitasertib (CX-4945), a Clinically Used CK2-Kinase Inhibitor with Additional Effects on GSK3β and DYRK1A Kinases: A Structural Perspective

Authors: Przemyslaw Grygier, Katarzyna Pustelny, Jakub Nowak, Przemyslaw Golik, Grzegorz M Popowicz, Oliver Plettenburg, Grzegorz Dubin, Filipe Menezes, Anna Czarna

Journal: J Med Chem

PubMed ID: 36883902

Doi: 10.1021/acs.jmedchem.2c01887

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Cryopreservation modifies the distribution of the prostate-derived lectin SL15 on the llama (Lama glama) sperm

Authors: Renato Zampini, Ximena A Castro-González, Micaela Scandura, Luciana M Sari, Ana V Diaz, Alfredo Martin, Martin E Argañaraz, Silvana A Apichela

Journal: Theriogenology

PubMed ID: 36933286

Doi: 10.1016/j.theriogenology.2023.03.006

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Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases

Authors: George D Lampe, Rebeca T King, Tyler S Halpin-Healy, Sanne E Klompe, Marcus I Hogan, Phuc Leo H Vo, Stephen Tang, Alejandro Chavez, Samuel H Sternberg

Journal: biorxiv

PubMed ID: 36993517

Doi: 10.1101/2023.03.17.533036

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KRT5 mutation regulate melanin metabolism through notch signalling pathway between keratinocytes and melanocytes

Authors: Weixue Jia, Yuanyuan Zhang, Xue Wang, Lingling Luo, Heng Sun, Yiqun Jiang, Jianbo Wang, Qiuxia Mao, Youming Guo, Lingzhuo Kong, Ran Mo, Chengrang Li

Journal: Exp Dermatol

PubMed ID: 36809573

Doi: 10.1111/exd.14761

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Immunoglobulin G subclasses confer protection against bloodstream dissemination through distinct mechanisms in mouse models

Authors: Xinhai Chen, Haley Gula, Tonu Pius, Chong Ou, Margaryta Gomozkova, Lai-Xi Wang, Olaf Schneewind, Dominique Missiakas

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36972444

Doi: 10.1073/pnas.2220765120

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High-force catch bonds between the Staphylococcus aureus surface protein SdrE and complement regulator factor H drive immune evasion

Authors: Telmo O Paiva, Joan A Geoghegan, Yves F Dufrêne

Journal: Commun Biol

PubMed ID: 36944849

Doi: 10.1038/s42003-023-04660-1

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Nanotopographic micro-nano forces finely tune the conformation of macrophage mechanosensitive membrane protein integrin β to manipulate inflammatory responses

Authors: Yuanlong Guo, Yong Ao, Chen Ye, Ruidi Xia, Jiaomei Mi, Zhengjie Shan, Mengru Shi, Lv Xie, Zetao Chen

Journal: Nano Res

PubMed ID: 37359074

Doi: 10.1007/s12274-023-5550-0

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Design and preclinical evaluation of a universal SARS-CoV-2 mRNA vaccine

Authors: Jane Qin, Ju Hyeong Jeon, Jiangsheng Xu, Laura Katherine Langston, Ramesh Marasini, Stephanie Mou, Brian Montoya, Carolina R Melo-Silva, Hyo Jin Jeon, Tianyi Zhu, Luis J Sigal, Renhuan Xu, Huabin Zhu

Journal: Front Immunol

PubMed ID: 37033973

Doi: 10.3389/fimmu.2023.1126392

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Novel multi-epitope vaccine against bovine brucellosis: approach from immunoinformatics to expression

Authors: Somayyeh Rahimnahal, Shahnaz Yousefizadeh, Yahya Mohammadi

Journal: J Biomol Struct Dyn

PubMed ID: 36927475

Doi: 10.1080/07391102.2023.2188962

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Entropy-driven assisted T7 RNA polymerase amplification-activated CRISPR/Cas13a activity for SARS-CoV-2 detection in human pharyngeal swabs and environment by an electrochemiluminescence biosensor

Authors: Jihua Wei, Zichun Song, Jiuying Cui, Yuanxun Gong, Qianli Tang, Kai Zhang, Xinlei Song, Xianjiu Liao

Journal: J Hazard Mater

PubMed ID: 36965355

Doi: 10.1016/j.jhazmat.2023.131268

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Exploring the structural basis to develop efficient multi-epitope vaccines displaying interaction with HLA and TAP and TLR3 molecules to prevent NIPAH infection, a global threat to human health

Authors: Sukrit Srivastava, Sonia Verma, Mohit Kamthania, Ajay Kumar Saxena, Kailash C Pandey, Veena Pande, Michael Kolbe

Journal: PLoS ONE

PubMed ID: 36920996

Doi: 10.1371/journal.pone.0282580

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Plasticity in airway smooth muscle differentiation during mouse lung development

Authors: Katharine Goodwin, Bezia Lemma, Pengfei Zhang, Adam Boukind, Celeste M Nelson

Journal: Dev Cell

PubMed ID: 36868232

Doi: 10.1016/j.devcel.2023.02.002

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Alphaherpesvirus upregulates NDRG1 expression to facilitate the nuclear import of viral UL31 and UL34 proteins

Authors: Shuang Zhang, Sheng-Li Ming, Lei Zeng, Lu-Fang Wang, Chao Zhang, He-Shui Zhu, Guo-Yu Yang, Gai-Ping Zhang, Bei-Bei Chu, Jiang Wang

Journal: J Med Virol

PubMed ID: 36807585

Doi: 10.1002/jmv.28591

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Structural basis for motilin and erythromycin recognition by motilin receptor

Authors: Chongzhao You, Yumu Zhang, Youwei Xu, Peiyu Xu, Zhen Li, Huadong Li, Sijie Huang, Zecai Chen, Jingru Li, H Eric Xu, Yi Jiang

Journal: SCIENCE ADVANCES

PubMed ID: 36921049

Doi: 10.1126/sciadv.ade9020

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Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity

Authors: Tong Han, Xujun Wang, Sailing Shi, Wubing Zhang, Jue Wang, Qiu Wu, Ziyi Li, Jingxin Fu, Rongbin Zheng, Jiamin Zhang, Qin Tang, Peng Zhang, Chenfei Wang

Journal: Cancer immunology research

PubMed ID: 36629846

Doi: 10.1158/2326-6066.CIR-22-0056

Products & Services: Protein Electrophoresis and Western Protein Electrophoresis and Western

Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge

Authors: Ebony N Gary, Nicholas J Tursi, Bryce M Warner, Gina Cuismano, Jennifer Connors, Elizabeth M Parzych, Bryan D Griffin, Matthew R Bell, Ali R Ali, Drew Frase, Casey E Hojecki, Gabriela A Canziani, Irwin Chaiken, Toshitha Kannan, Estella Moffat, Carissa Embury-Hyatt, Sarah K Wooton, Andrew Kossenkov, Ami Patel, Darwyn Kobasa, Michele A Kutzler, Elias K Haddad, David B Weiner

Journal: Front Immunol

PubMed ID: 36999023

Doi: 10.3389/fimmu.2023.1138609

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Identification of specific and shared epitopes at the extreme N-terminal VP1 of Coxsackievirus A4, A2 and A5 by monoclonal antibodies

Authors: Yu-Xuan Tian, Wei-Ping Jin, Zhen-Ni Wei, Shi-Yun Lv, Meng-Jun Wang, Sheng-Li Meng, Jing Guo, Ze-Jun Wang, Shuo Shen

Journal: Virus Res

PubMed ID: 36805409

Doi: 10.1016/j.virusres.2023.199074

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PF-D-Trimer, a protective SARS-CoV-2 subunit vaccine: immunogenicity and application

Authors: Zhihao Zhang, Jinhu Zhou, Peng Ni, Bing Hu, Normand Jolicoeur, Shuang Deng, Qian Xiao, Qian He, Gai Li, Yan Xia, Mei Liu, Cong Wang, Zhizheng Fang, Nan Xia, Zhe-Rui Zhang, Bo Zhang, Kun Cai, Yan Xu, Binlei Liu

Journal: npj Vaccines

PubMed ID: 36922524

Doi: 10.1038/s41541-023-00636-8

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Active Site Aromatic Residues Play a Dual Role in the Substrate Interaction and Protein Structure in Functional Dimers of CYP121A1 of

Authors: Christopher S Campomizzi, Amit Kumar, Patil Pranita Uttamrao, Jack J Stallone, George E Ghanatios, Thenmalarchelvi Rathinavelan, D Fernando Estrada

Journal: ACS Infect Dis

PubMed ID: 36976833

Doi: 10.1021/acsinfecdis.2c00531

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A chemically controlled Cas9 switch enables temporal modulation of diverse effectors

Authors: Cindy T Wei, Nicholas A Popp, Omri Peleg, Rachel L Powell, Elhanan Borenstein, Dustin J Maly, Douglas M Fowler

Journal: Nat Chem Biol

PubMed ID: 36879061

Doi: 10.1038/s41589-023-01278-6

Products & Services: Codon Optimization

High Autophagy Patterns in Swelling Platelets During Apheresis Platelet Storage

Authors: Lu Yu, Shifang Yu, Yunlei He, Gang Deng, Qiang Li

Journal: Indian J Hematol Blood Transfus

PubMed ID: 37790743

Doi: 10.1007/s12288-023-01638-1

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Fine-tuning Bacterial Cyclic di-AMP Production for Durable Antitumor Effects Through the Activation of the STING Pathway

Authors: Yu Jiang, Xiyuan Li, Fenghui Qian, Bingbing Sun, Xiyuan Wang, Yan Zhang, Deqiang Zhang, Meiyu Geng, Zuoquan Xie, Sheng Yang

Journal: Research (Wash D C)

PubMed ID: 37011280

Doi: 10.34133/research.0102

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Antitumor effect of neoantigen-reactive T cells combined with PD1 inhibitor therapy in mouse lung cancer

Authors: Huan Qin, Haiyan Hu, Ximing Liao, Pei Zhao, Wenjuan He, Xiaoping Su, Jiaxing Sun, Qiang Li

Journal: J Cancer Res Clin Oncol

PubMed ID: 36933035

Doi: 10.1007/s00432-023-04683-5

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Authors: Sarah Temmam, Xavier Montagutelli, Cécile Herate, Flora Donati, Béatrice Regnault, Mikael Attia, Eduard Baquero Salazar, Delphine Chretien, Laurine Conquet, Grégory Jouvion, Juliana Pipoli Da Fonseca, Thomas Cokelaer, Faustine Amara, Francis Relouzat, Thibaut Naninck, Julien Lemaitre, Nathalie Derreudre-Bosquet, Quentin Pascal, Massimiliano Bonomi, Thomas Bigot, Sandie Munier, Felix A Rey, Roger Le Grand, Sylvie van der Werf, Marc Eloit

Journal: EMBO Rep

PubMed ID: 36876574

Doi: 10.15252/embr.202256055

Products & Services: Recombinant Proteins

The diurnal salivary glands transcriptome of Dermacentor nuttalli from the first four days of blood feeding

Authors: Hejia Ma, Yanjun Lao, Susu Liu, Jingkai Ai, Xue Sun, Wei Zhang, Ming Kang, Jixu Li, Yali Sun

Journal: Ticks Tick Borne Dis

PubMed ID: 37001418

Doi: 10.1016/j.ttbdis.2023.102178

Products & Services: PCR Cloning and Subcloning

Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines

Authors: Thayne H Dickey, Rui Ma, Sachy Orr-Gonzalez, Tarik Ouahes, Palak Patel, Holly McAleese, Brandi Butler, Elizabeth Eudy, Brett Eaton, Michael Murphy, Jennifer L Kwan, Nichole D Salinas, Michael R Holbrook, Lynn E Lambert, Niraj H Tolia

Journal: Cell Rep

PubMed ID: 36943870

Doi: 10.1016/j.celrep.2023.112266

Products & Services: Recombinant Proteins

On the design of a constitutively active peptide asparaginyl ligase for facile protein conjugation

Authors: Niying Chua, Yee Hwa Wong, Abbas El Sahili, Chuan Fa Liu, Julien Lescar

Journal: FEBS Open Bio

PubMed ID: 36788723

Doi: 10.1002/2211-5463.13575

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Ferulic Acid Alleviates Hepatic Lipid Accumulation and Inflammation by Improving Proximal and Distal Intestinal Barriers in NAFLD Mice

Authors: Jiaojiao Fu, Jingyan Yang, Liying He, Caixia Yang, Jing He, Yanan Hua, Jinlin Guo, Sijing Liu

Journal: Tohoku J Exp Med

PubMed ID: 36927682

Doi: 10.1620/tjem.2023.J023

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RHINO restricts MMEJ activity to mitosis

Authors: Alessandra Brambati, Olivia Sacco, Sarina Porcella, Joshua Heyza, Mike Kareh, Jens C Schmidt, Agnel Sfeir

Journal: biorxiv

PubMed ID: 36993461

Doi: 10.1101/2023.03.16.532763

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Urease of Aspergillus fumigatus Is Required for Survival in Macrophages and Virulence

Authors: Zhenzhen Xiong, Nan Zhang, Liru Xu, Zhiduo Deng, Jarukitt Limwachiranon, Yaojie Guo, Yi Han, Wei Yang, Daniel H Scharf

Journal: Microbiol Spectr

PubMed ID: 36916906

Doi: 10.1128/spectrum.03508-22

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Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases

Authors: George D Lampe, Rebeca T King, Tyler S Halpin-Healy, Sanne E Klompe, Marcus I Hogan, Phuc Leo H Vo, Stephen Tang, Alejandro Chavez, Samuel H Sternberg

Journal: Nat Biotechnol

PubMed ID: 36991112

Doi: 10.1038/s41587-023-01748-1

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Mapping the conformational landscape of the stimulatory heterotrimeric G protein

Authors: Shuya Kate Huang, Louis-Philippe Picard, Rima S M Rahmatullah, Aditya Pandey, Ned Van Eps, Roger K Sunahara, Oliver P Ernst, Adnan Sljoka, R Scott Prosser

Journal: Nat Struct Mol Biol

PubMed ID: 36997760

Doi: 10.1038/s41594-023-00957-1

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Vimentin Is an Attachment Receptor for Mycoplasma pneumoniae P1 Protein

Authors: Kailan Peng, Yating Liao, Xia Li, Dongdong Zeng, Youyuan Ye, Li Chen, Zhuo Zeng, Yanhua Zeng

Journal: Microbiol Spectr

PubMed ID: 36912679

Doi: 10.1128/spectrum.04489-22

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Human immunoglobulin gene allelic variation impacts germline-targeting vaccine priming

Authors: Allan C deCamp, Martin M Corcoran, William J Fulp, Jordan R Willis, Christopher A Cottrell, Daniel L V Bader, Oleksandr Kalyuzhniy, David J Leggat, Kristen W Cohen, Ollivier Hyrien, Sergey Menis, Greg Finak, Lamar Ballweber-Fleming, Abhinaya Srikanth, Jason R Plyler, Farhad Rahaman, Angela Lombardo, Vincent Philiponis, Rachael E Whaley, Aaron Seese, Joshua Brand, Alexis M Ruppel, Wesley Hoyland, Celia R Mahoney, Alberto Cagigi, Alison Taylor, David M Brown, David R Ambrozak, Troy Sincomb, Tina-Marie Mullen, Janine Maenza, Orpheus Kolokythas, Nadia Khati, Jeffrey Bethony, Mario Roederer, David Diemert, Richard A Koup, Dagna S Laufer, Juliana M McElrath, Adrian B McDermott, Gunilla B Karlsson Hedestam, William R Schief

Journal: medrxiv

PubMed ID: 36993183

Doi: 10.1101/2023.03.10.23287126

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Structure-activity relationship of GPR15L peptide analogues and investigation of their interaction with the GPR15 receptor

Authors: Yufang Deng, Claudia V Perez Almeria, Lieke van Gijzel, Kay Schaller, Line Vedel, David E Gloriam, Trond Ulven, Hans Bräuner-Osborne

Journal: Basic Clin Pharmacol Toxicol

PubMed ID: 36930875

Doi: 10.1111/bcpt.13861

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A short-chain carbonyl reductase mutant is an efficient catalyst in the production of (R)-1,3-butanediol

Authors: Xiaoyan Guo, Yunfang Gao, Fangzheng Liu, Yong Tao, Haibo Jin, Jianjun Wang, Sheng Wu

Journal: Microb Biotechnol

PubMed ID: 36946330

Doi: 10.1111/1751-7915.14249

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Impact of homologous and heterologous boosters in neutralizing antibodies titers against SARS-CoV-2 Omicron in solid-organ transplant recipients

Authors: Aracelly Gaete-Argel, Vicente Saavedra-Alarcón, Denis Sauré, Luis Alonso-Palomares, Mónica L Acevedo, Marion Alarcón, Susan M Bueno, Alexis M Kalergis, Ricardo Soto-Rifo, Fernando Valiente-Echeverría, Claudia P Cortes

Journal: Front Immunol

PubMed ID: 36999018

Doi: 10.3389/fimmu.2023.1135478

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Production of neutralizing antibody fragment variants in the cytoplasm of E coli for rapid screening: SARS-CoV-2 a case study

Authors: Aatir A Tungekar, Rosario Recacha, Lloyd W Ruddock

Journal: Sci Rep

PubMed ID: 36927743

Doi: 10.1038/s41598-023-31369-2

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Myosin-X recruits lamellipodin to filopodia tips

Authors: Ana Popović, Mitro Miihkinen, Sujan Ghimire, Rafael Saup, Max L B Grönloh, Neil J Ball, Benjamin T Goult, Johanna Ivaska, Guillaume Jacquemet

Journal: J Cell Sci

PubMed ID: 36861887

Doi: 10.1242/jcs.260574

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Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders

Authors: Elżbieta Wątor , Piotr Wilk , Artur Biela, Michał Rawski , Krzysztof M Zak, Wieland Steinchen , Gert Bange, Sebastian Glatt , Przemysław Grudnik

Journal: Nature Communications

PubMed ID: 36973244

Doi: 10.1038/s41467-023-37305-2

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Genome-wide identification and characterization of tomato 14–3-3 (SlTFT) genes and functional analysis of SlTFT6 under heat stress

Authors: Yunfei Liang, Fang Ma, Ruili Zhang, Wenyu Li, Jiao Dang, Huai Su, Boyu Li, Tixu Hu, Mingke Zhang, Yan Liang, Xiangqiang Zhan

Journal: Physiologia plantarum

PubMed ID: 36906839

Doi: 10.1111/ppl.13888

Products & Services: Transient Expression(INACTIVE)

Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel

Authors: Mingfeng Zhang, Yuanyue Shan, Duanqing Pei

Journal: nature COMMUNICATION

PubMed ID: 36928654

Doi: 10.1038/s41467-023-37204-6

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A swapped genetic code prevents viral infections and gene transfer

Authors: Akos Nyerges, Svenja Vinke, Regan Flynn, Siân V Owen, Eleanor A Rand, Bogdan Budnik, Eric Keen, Kamesh Narasimhan, Jorge A Marchand, Maximilien Baas-Thomas, Min Liu, Kangming Chen, Anush Chiappino-Pepe, Fangxiang Hu, Michael Baym, George M Church

Journal: Nature

PubMed ID: 36922599

Doi: 10.1038/s41586-023-05824-z

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A riboswitch separated from its ribosome-binding site still regulates translation

Authors: Griffin M Schroeder, Olayinka Akinyemi, Jeffrey Malik, Caroline M Focht, Elizabeth M Pritchett, Cameron D Baker, James P McSally, Jermaine L Jenkins, David H Mathews, Joseph E Wedekind

Journal: Nucleic Acids Research

PubMed ID: 36762498

Doi: 10.1093/nar/gkad056.

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Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex

Authors: Peng Liu, Tian Xie, Xinyue Wu, Gongshe Han, Sita D Gupta, Zike Zhang, Jian Yue, Feitong Dong, Kenneth Gable, Somashekarappa Niranjanakumari, Wanyuan Li, Lin Wang, Wenchen Liu, Ruifeng Yao, Edgar B Cahoon, Teresa M Dunn, Xin Gong

Journal: SCIENCE ADVANCES

PubMed ID: 36989369

Doi: 10.1126/sciadv.adg0728

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Mucus-penetrating nonviral gene vaccine processed in the epithelium for inducing advanced vaginal mucosal immune responses

Authors: Qunjie Bi, Xu Song, Yangyang Zhao, Xueyi Hu, Huan Yang, Rongrong Jin, Yu Nie

Journal: Acta Pharmacuetica Sinica.B

PubMed ID: 36970203

Doi: 10.1016/j.apsb.2022.11.004

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Fabrication of bFGF/polydopamine-loaded PEEK implants for improving soft tissue integration by upregulating Wnt/β-catenin signaling

Authors: Xiaohu Wang, Ning Ma, Li Feng, Mingkui Shen, Yaqi Zhou, Xinan Zhang, Ruichao Huang, Li Zhou, Shanfeng Ji, Yongli Lou, Zhi Zhu