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Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II

Authors: David Flores-Solis, Irina P Lushpinskaia, Anton A Polyansky, Arya Changiarath, Marc Boehning, Milana Mirkovic, James Walshe, Lisa M Pietrek, Patrick Cramer, Lukas S Stelzl, Bojan Zagrovic, Markus Zweckstetter

Journal: Nat Commun

PubMed ID: 37749095

Doi: 10.1038/s41467-023-41633-8

Products & Services: Protein and Antibody Isolation

A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo

Authors: Burcu Bestas, Sandra Wimberger, Dmitrii Degtev, Alexandra Madsen, Antje K Rottner, Fredrik Karlsson, Sergey Naumenko, Megan Callahan, Julia Liz Touza, Margherita Francescatto, Carl Ivar Möller, Lukas Badertscher, Songyuan Li, Silvia Cerboni, Niklas Selfjord, Elke Ericson, Euan Gordon, Mike Firth, Krzysztof Chylinski, Amir Taheri-Ghahfarokhi, Mohammad Bohlooly-Y, Mike Snowden, Menelaos Pangalos, Barrett Nuttall, Pinar Akcakaya, Grzegorz Sienski, Marcello Maresca

Journal: Nat Commun

PubMed ID: 37673883

Doi: 10.1038/s41467-023-41240-7

Products & Services: Protein and Antibody Isolation

One-step production of fully biotinylated and glycosylated human Fc gamma receptors

Authors: Minhyo Kang, Zening Wang, Xin Ge

Journal: Biotechnol Prog

PubMed ID: 37734055

Doi: 10.1002/btpr.3392

Products & Services: Protein and Antibody Isolation

Host Interactions with Engineered T-cell Micropharmacies

Authors: Christopher M Bourne, Patrick Wallisch, Megan M Dacek, Thomas J Gardner, Stephanie Pierre, Kristen Vogt, Broderick C Corless, Mamadou A Bah, Jesus E Romero-Pichardo, Angel Charles, Keifer G Kurtz, Derek S Tan, David A Scheinberg

Journal: Cancer Immunol Res

PubMed ID: 37379366

Doi: 10.1158/2326-6066.CIR-22-0879

Products & Services: Molecular Biology Reagents

PAR4 Inhibition Reduces Coronary Artery Atherosclerosis and Myocardial Fibrosis in SR-B1/LDLR Double Knockout Mice

Authors: Samuel K Lee, Rida A Malik, Ji Zhou, Wei Wang, Peter L Gross, Jeffrey I Weitz, Rithwik Ramachandran, Bernardo L Trigatti

Journal: Arterioscler Thromb Vasc Biol

PubMed ID: 37675637

Doi: 10.1161/ATVBAHA.123.319767

Products & Services: Molecular Biology Reagents

Prime editor-mediated functional reshaping of ACE2 prevents the entry of multiple human coronaviruses, including SARS-CoV-2 variants

Authors: Wenwen Zhao， Jifang Li, Xiao Wang， Wei Xu， Bao-Qing Gao， Jiangchao Xiang， Yaofeng Hou, Wei Liu, Jing Wu, Qilian Qi, Jia Wei, Xiaoyu Yang, Lu Lu,Li Yang, Jia Chen, Bei Yang

Journal: MedComm.

Doi: 10.1002/mco2.356

Products & Services: Gene Synthesis Protein and Antibody Isolation

PCAP-1a, an exopolysaccharide from Pectobacterium actinidiae, exerts the dual role of immunogenicity and virulence in plants

Authors: Zhixiang Yuan , Tingmi Yang , Qingping Xiong , Yuqi Shi , Xixi Han , Yuqing Lin , Njoroge Hellen Wambui , Zhuang Liu , Yunpeng Wang , Hongxia Liu

Journal: Carbohydrate Polymers

Doi: 10.1016/j.carbpol.2023.121390

Products & Services: Protein Electrophoresis and Western

mRNA vaccines encoding fusion proteins of monkeypox virus antigens protect mice from vaccinia virus challenge

Authors: Fujun Hou, Yuntao Zhang, Xiaohu Liu, Yanal M Murad, Jiang Xu, Zhibin Yu, Xianwu Hua, Yingying Song, Jun Ding, Hongwei Huang, Ronghua Zhao, William Jia, Xiaoming Yang

Journal: Nat Commun

PubMed ID: 37739969

Doi: 10.1038/s41467-023-41628-5

Products & Services: Codon Optimization

Isofagomine inhibits multiple TcdB variants and protects mice from induced mortality

Authors: Ashleigh S Paparella, Isabella Brew, Huynh A Hong, William Ferriera, Simon Cutting, Farah Lamiable-Oulaidi, Michael Popadynec, Peter C Tyler, Vern L Schramm

Journal: biorxiv

PubMed ID: 37781587

Doi: 10.1101/2023.09.19.558375

Products & Services: Combinatorial Mutant library

CDK10 suppresses metastasis of lung adenocarcinoma through inhibition of the ETS2/c-Raf/p-MEK/p-ERK signaling loop

Authors: Xiujuan Zhang, Yu Zhao, Ruzetuoheti Yiminniyaze, Ning Zhu, Yuanyuan Zhang, Gulinuer Wumaier, Jingwen Xia, Liang Dong, Daibing Zhou, Jing Wang, Chengwei Li, Youzhi Zhang, Shengqing Li

Journal: Mol Carcinog

PubMed ID: 37737453

Doi: 10.1002/mc.23636

Products & Services: Molecular Biology Reagents