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The cryo-EM-delineated mechanism underlying mimicry of CXCR4 agonism enables widespread stem cell neuroprotection in a mouse model of ALS

Authors: Xiaohong Sang; Haizhan Jiao; Qian Meng; Xiong Fang; Kartik S. Sundaram; Jiao Zhou; Yan Xu; Asuka I. W. Alvarado; Ruslan L. Nuryyev; Jitka Ourenik; Vaclav Ourednik; Iris S. Huang; Xiang Liu; Yuheng Mei; Tingli Qian; Aaron Ciechanover; Donald P. Pizzo; Michael A. Lane; Lyandysha V. Zholudeva; Jing An; Evan Y. Snyder; Hongli Hu; Ziwei Huang

Journal: biorxiv

PubMed ID: 40672153

Doi: 10.1101/2025.07.08.663251

Products & Services: Protein and Antibody Isolation

Coordinated regulation by lncRNAs results in tight lncRNA-target couplings

Authors: Hua-Sheng Chiu; Sonal Somvanshi; Chung-Te Chang; Eric James de Bony de Lavergne; Zhaowen Wei; Chih-Hung Hsieh; Wim Trypsteen; Kathleen A. Scorsone; Ektaben Patel; Tien T. Tang; David B. Flint; Mohammad Javad Najaf Panah; Hyunjae Ryan Kim; Purva Rathi; Yan-Hwa Wu Lee; Sarah E. Woodfield; Sanjeev A. Vasudevan; Andras Attila Heczey; M. Waleed Gaber; Gabriel O. Sawakuchi; Ting-Wen Chen; Pieter Mestdagh; Xuerui Yang; Pavel Sumazin

Journal: Cell Genomics

PubMed ID: 40628267

Doi: 10.1016/j.xgen.2025.100927

Coordinated regulation by lncRNAs results in tight lncRNA-target couplings

Journal: Cell Genomics

PubMed ID: 40628267

Doi: 10.1016/j.xgen.2025.100927

Novel In Silico mRNA vaccine design exploiting proteins of M. tuberculosis that modulates host immune responses by inducing epigenetic modifications

Authors: H. Al Tbeishat

Journal: Scientific REPORTS

PubMed ID: 35301360

Doi: 10.1038/s41598-022-08506-4

Products & Services: Codon Optimization

TgLaforin, a glucan phosphatase, reveals the dynamic role of storage polysaccharides in tachyzoites and bradyzoites

Authors: Robert D Murphy, Cortni A Troublefield, Joy S Miracle, Lyndsay E A Young, Corey O Brizzee, Animesh Dhara, Ramon C Sun, Craig W Vander Kooi, Matthew S Gentry, Anthony P Sinai

Journal: biorxiv

PubMed ID: 37808860

Doi: 10.1101/2023.09.29.560185

Products & Services: Protein and Antibody Isolation

Optimizing effector functions of monoclonal antibodies via tailored N-glycan engineering using a dual landing pad CHO targeted integration platform

Authors: Ngan T B Nguyen, Hau Wan Leung, Kuin Tian Pang, Shi Jie Tay, Ian Walsh, Andre B H Choo, Yuansheng Yang

Journal: Sci Rep

PubMed ID: 37731040

Doi: 10.1038/s41598-023-42925-1

Products & Services: Protein and Antibody Isolation

Loss of function of FIGNL1, a DNA damage response gene, causes human ovarian dysgenesis

Authors: Natan Florsheim, Larisa Naugolni, Fouad Zahdeh, Orit Lobel, Batel Terespolsky, Rachel Michaelson-Cohen, Merav Y Gold, Michal Goldberg, Paul Renbaum, Ephrat Levy-Lahad, David Zangen

Journal: Eur J Endocrinol

PubMed ID: 37740949

Doi: 10.1093/ejendo/lvad127

Products & Services: Protein and Antibody Isolation

Is the co-option of jasmonate signalling for botanical carnivory universal trait for all carnivorous plants?

Authors: Andrej Pavlovič, Jana Koller, Ondřej Vrobel, Ivo Chamrád, René Lenobel, Peter Tarkowski

Journal: J Exp Bot

PubMed ID: 37708289

Doi: 10.1093/jxb/erad359

Products & Services: Protein and Antibody Isolation

Acute and Long-Term Consequences of Co-opted doublesex on the Development of Mimetic Butterfly Color Patterns

Authors: Nicholas W VanKuren, Meredith M Doellman, Sofia I Sheikh, Daniela H Palmer Droguett, Darli Massardo, Marcus R Kronforst