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Coordinated regulation by lncRNAs results in tight lncRNA-target couplings

Authors: Hua-Sheng Chiu; Sonal Somvanshi; Chung-Te Chang; Eric James de Bony de Lavergne; Zhaowen Wei; Chih-Hung Hsieh; Wim Trypsteen; Kathleen A. Scorsone; Ektaben Patel; Tien T. Tang; David B. Flint; Mohammad Javad Najaf Panah; Hyunjae Ryan Kim; Purva Rathi; Yan-Hwa Wu Lee; Sarah E. Woodfield; Sanjeev A. Vasudevan; Andras Attila Heczey; M. Waleed Gaber; Gabriel O. Sawakuchi; Ting-Wen Chen; Pieter Mestdagh; Xuerui Yang; Pavel Sumazin

Journal: Cell Genomics

PubMed ID: 40628267

Doi: 10.1016/j.xgen.2025.100927

Novel In Silico mRNA vaccine design exploiting proteins of M. tuberculosis that modulates host immune responses by inducing epigenetic modifications

Authors: H. Al Tbeishat

Journal: Scientific REPORTS

PubMed ID: 35301360

Doi: 10.1038/s41598-022-08506-4

Products & Services: Codon Optimization

CRISPR-ChIP reveals selective regulation of H3K79me2 by Menin in MLL leukemia

Authors: Omer Gilan, Laure Talarmain, Charles C Bell, Daniel Neville, Kathy Knezevic, Daniel T Ferguson, Marion Boudes, Yih-Chih Chan, Chen Davidovich, Enid Y N Lam, Mark A Dawson

Journal: Nat Struct Mol Biol

PubMed ID: 37679565

Doi: 10.1038/s41594-023-01087-4

Products & Services: Protein and Antibody Isolation

Differential regulatory control of curli (csg) gene expression in Salmonella enterica serovar Typhi requires more than a functional CsgD regulator

Authors: Camille Ou, Charles M Dozois, France Daigle

Journal: Sci Rep

PubMed ID: 37689734

Doi: 10.1038/s41598-023-42027-y

Products & Services: Monoclonal Antibody Services

Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding

Authors: Ladan Khodaparast, Laleh Khodaparast, Guiqin Wu, Emiel Michiels, Rodrigo Gallardo, Bert Houben, Teresa Garcia, Matthias De Vleeschouwer, Meine Ramakers, Hannah Wilkinson, Ramon Duran-Romaña, Johan Van Eldere, Frederic Rousseau, Joost Schymkowitz

Journal: Nat Commun

PubMed ID: 37689716

Doi: 10.1038/s41467-023-41191-z

Products & Services: Peptide Synthesis

Development of a plant-based oral vaccine candidate against the bovine respiratory pathogen

Authors: Angelo Kaldis, Muhammed Salah Uddin, Jose Ortiz Guluarte, Coby Martin, Trevor W Alexander, Rima Menassa

Journal: Front Plant Sci

PubMed ID: 37790785

Doi: 10.3389/fpls.2023.1251046

Products & Services: Recombinant Antibody Expression

A Proteorhodopsin-Related Photosensor Expands the Repertoire of Structural Motifs Employed by Sensory Rhodopsins

Authors: Maryam Saliminasab, Yoichi Yamazaki, Alyssa Palmateer, Andrew Harris, Luiz Schubert, Pit Langner, Joachim Heberle, Ana-Nicoleta Bondar, Leonid S Brown

Journal: J Phys Chem B

PubMed ID: 37694950

Doi: 10.1021/acs.jpcb.3c04032

Products & Services: Mutant Libraries Mutagenesis Services Gene Synthesis

Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease

Authors: Yugendar R Alugubelli, Jing Xiao, Kaustav Khatua, Sathish Kumar, Yuying Ma, Xinyu R Ma, Veerabhadra R Vulupala, Sandeep R Atla, Lauren Blankenship, Demonta Coleman, Benjamin W Neuman, Wenshe Ray Liu, Shiqing Xu

Journal: biorxiv

PubMed ID: 37808777

Doi: 10.1101/2023.09.29.560163

Products & Services: Protein and Antibody Isolation

CST2 is activated by RUNX1 and promotes pancreatic cancer progression by activating PI3K/AKT pathway

Authors: Rongwen Ou, Chengjie Lin, Youting Chen

Journal: Arch Biochem Biophys

PubMed ID: 37722526

Doi: 10.1016/j.abb.2023.109760

Products & Services: Custom RNAi Services

A Humanized Yeast System for Evaluating the Protein Prenylation of a Wide Range of Human and Viral CaaX Sequences

Authors: Emily R Hildebrandt, Anushka Sarkar, Rajani Ravishankar, June H Kim, Walter K Schmidt