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Nucleic acid-triggered NADase activation of a short prokaryotic Argonaute

Authors: Xiaopan Gao , Kun Shang , Kaixiang Zhu , Linyue Wang , Zhixia Mu , Xingke Fu , Xia Yu , Bo Qin , Hongtao Zhu , Wei Ding , Sheng Cui

Journal: Nature .

PubMed ID: 37783228

Doi: 10.1038/s41586-023-06665-6

Products & Services: DNA Sequencing

Molecular basis of methyl-salicylate-mediated plant airborne defence

Authors: Qian Gong , Yunjing Wang , Linfang He , Fan Huang , Danfeng Zhang , Yan Wang , Xiang Wei , Meng Han , Haiteng Deng , Lan Luo , Feng Cui , Yiguo Hong, Yule Liu

Journal: Nature .

PubMed ID: 37704724

Doi: 10.1038/s41586-023-06533-3

Products & Services: Protein and Antibody Isolation

Plant-Based Meat Analogues Weaken Gastrointestinal Digestive Function and Show Less Digestibility Than Real Meat in Mice

Authors: Yunting Xie , Linlin Cai , Zhiji Huang , Kai Shan , Xinglian Xu , Guanghong Zhou , Chunbao Li

Journal: J Agric Food Chem .

PubMed ID: 36070521

Doi: 10.1021/acs.jafc.2c04246

Products & Services: Gene Synthesis

Examining the Potential Formation of Ternary DNA Complexes with Chromium‑Cysteine, Chromium-Ascorbate, and Chromium-Glutathione and Implications for Their Carcinogenicity

Authors: Sydney Marchi , Emma Lankford , Bradley Dorin , Eilidh Drummond , Sumner C Thomas , Stephen A Woski , John B Vincent

Journal: Biol Trace Elem Res .

PubMed ID: 36662348

Doi: 10.1007/s12011-023-03573-8

Products & Services: Custom DNA/RNA Oligos

Rapamycin nanoparticles increase the therapeutic window of engineered interleukin-2 and drive expansion of antigen-specific regulatory T cells for protection against autoimmune disease

Authors: Takashi Kei Kishimoto, Max Fournier, Alicia Michaud, Gina Rizzo, Christopher Roy, Teresa Capela, Natasha Nukolova, Ning Li, Liam Doyle, Fen-Ni Fu, Derek VanDyke, Peter G Traber, Jamie B Spangler, Sheldon S Leung, Petr O Ilyinskii

Journal: J Autoimmun

PubMed ID: 37844543

Doi: 10.1016/j.jaut.2023.103125

Products & Services: Protein and Antibody Isolation

Analytical Ultracentrifugation Detects Quaternary Rearrangements and Antibody-Induced Conformational Selection of the SARS-CoV-2 Spike Trimer

Authors: Giuditta Guerrini, Dora Mehn, Francesco Fumagalli, Sabrina Gioria, Mattia Pedotti, Luca Simonelli, Filippo Bianchini, Davide F Robbiani, Luca Varani, Luigi Calzolai

Journal: Int J Mol Sci

PubMed ID: 37834322

Doi: 10.3390/ijms241914875

Products & Services: Custom DNA/RNA Oligos

Binding mechanism and biological effects of flavone DYRK1A inhibitors for the design of new antidiabetics

Authors: Katarzyna Pustelny, Przemyslaw Grygier, Agata Barzowska, Barbara Pucelik, Alex Matsuda, Krzysztof Mrowiec, Emilia Slugocka, Grzegorz M Popowicz, Grzegorz Dubin, Anna Czarna

Journal: Sci Rep

PubMed ID: 37872245

Doi: 10.1038/s41598-023-44810-3

Products & Services: Plasmid DNA Preparation

Industry updates from the field of stem cell research and regenerative medicine in August 2023

Authors: Dusko Ilic, Mirjana Liovic

Journal: Regen Med

PubMed ID: 37786963

Doi: 10.2217/rme-2023-0181

Products & Services: Protein and Antibody Isolation

Author Correction: A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates

Authors: Payton A-B Weidenbacher, Mrinmoy Sanyal, Natalia Friedland, Shaogeng Tang, Prabhu S Arunachalam, Mengyun Hu, Ozan S Kumru, Mary Kate Morris, Jane Fontenot, Lisa Shirreff, Jonathan Do, Ya-Chen Cheng, Gayathri Vasudevan, Mark B Feinberg, Francois J Villinger, Carl Hanson, Sangeeta B Joshi, David B Volkin, Bali Pulendran, Peter S Kim

Journal: Nat Commun

PubMed ID: 37798288

Doi: 10.1038/s41467-023-42061-4

Products & Services: Peptide Synthesis

LRRK2 G2019S promotes astrocytic inflammation induced by oligomeric α-synuclein through NF-κB pathway

Authors: Kai-Jie He, Jin-Bao Zhang, Jun-Yi Liu, Feng-Lun Zhao, Xiao-Yu Yao, Yu-Ting Tang, Jin-Ru Zhang, Xiao-Yu Cheng, Li-Fang Hu, Fen Wang, Chun-Feng Liu

Journal: iScience

PubMed ID: 37876795

Doi: 10.1016/j.isci.2023.108130

Products & Services: Molecular Biology Reagents