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Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma
Authors: Tilman L B Hölting, Florencia Cidre-Aranaz, Dana Matzek, Bastian Popper, Severin J Jacobi, Cornelius M Funk, Florian H Geyer, Jing Li, Ignazio Piseddu, Bruno L Cadilha, Stephan Ledderose, Jennifer Zwilling, Shunya Ohmura, David Anz, Annette Künkele, Frederick Klauschen, Thomas G P Grünewald, Maximilian M L Knott
Journal: Mol Cancer
PubMed ID: 36229873
Doi: 10.1186/s12943-022-01641-6
Products & Services: Recombinant Proteins   
Active Pharmaceutical Ingredient Uptake by Zebrafish (Danio rerio) Oct2 (slc22a2) Transporter Expressed in Xenopus laevis Oocytes
Authors: Elisabeth D Chang, Stewart F Owen, Christer Hogstrand, Nic R Bury
Journal: Environ Toxicol Chem
PubMed ID: 36102855
Doi: 10.1002/etc.5480
Products & Services: Gene Synthesis   
Combating the SARS-CoV-2 Omicron (BA1) and BA2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Authors: Yingdan Wang, Xiang Zhang, Yunping Ma, Yanqun Wang, Wuqiang Zhan, Qinwen Zheng, Meng Zhang, Ping Ji, Mei Liu, Qianying Liu, Tingting Sun, Tongyu Zhu, Yumei Wen, Lei Sun, Jincun Zhao, Fan Wu, Zhenguo Chen, Jinghe Huang
Journal: Cell Discov
PubMed ID: 36207299
Doi: 10.1038/s41421-022-00463-6
Products & Services: Codon Optimization   
Discovery and functional characterization of the oncogenicity and targetability of a novel gene fusion in pediatric angiosarcoma
Authors: Payal Jain, Sudarshan Iyer, Joshua Straka, Lea F Surrey, Jennifer Pogoriler, Harry Han, Tiffany Smith, Christine Busch, Elizabeth Fox, Marilyn Li, Angela J Waanders, Adam Resnick, Monika A Davare
Journal: Cold Spring Harb Mol Case Stud
PubMed ID: 36307212
Doi: 10.1101/mcs.a006222
Products & Services: Plasmid DNA Preparation   
Transient State Kinetics of Apicoplast DNA Polymerase Suggests the Involvement of Accessory Factors for Efficient and Accurate DNA Synthesis
Authors: Anamika Kumari, Anjali Yadav, Indrajit Lahiri
Journal: Biochemistry
PubMed ID: 36251801
Doi: 10.1021/acs.biochem.2c00446
Products & Services: Custom Vector Construction   
A critical path to producing high quality, reproducible data from quantitative western blot experiments
Authors: Sean C Taylor, Luciana K Rosselli-Murai, Bélinda Crobeddu, Isabelle Plante
Journal: Sci Rep
PubMed ID: 36266411
Doi: 10.1038/s41598-022-22294-x
Products & Services: Proteins, Expression, Isolation and Analysis   
Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation
Authors: Wen-Hsin Lee, Xiaorui Chen, I-Ju Liu, Jiin-Horng Lee, Chun-Mei Hu, Han-Chung Wu, Sheng-Kai Wang, Wen-Hwa Lee, Che Ma
Journal: Cell Rep
PubMed ID: 36288706
Doi: 10.1016/j.celrep.2022.111555
Products & Services: Mammalian Expression   
Identification of human MHC-I HPV18 E6/E7-specific CD8 + T cell epitopes and generation of an HPV18 E6/E7-expressing adenosquamous carcinoma in HLA-A2 transgenic mice
Authors: Shiwen Peng, Deyin Xing, Louise Ferrall, Ya-Chea Tsai, Chien-Fu Hung, T-C Wu
Journal: J Biomed Sci
PubMed ID: 36224625
Doi: 10.1186/s12929-022-00864-5
Products & Services: Peptide Synthesis   
A broadly protective vaccine against cutaneous human papillomaviruses
Authors: Filipe Colaco Mariz, Kathrin Balz, Manuela Dittrich, Yueru Zhang, Fan Yang, Xueer Zhao, Angelo Bolchi, Simone Ottonello, Martin Müller
Journal: npj Vaccines
PubMed ID: 36216845
Doi: 10.1038/s41541-022-00539-0
Products & Services: Codon Optimization   
GITRL impairs the immunosuppressive function of MDSCs via PTEN-mediated signaling pathway in experimental Sjögren syndrome
Authors: Jie Tian, Beibei Zhang, Qingfang Yuan, Xueqing Sun, Na Peng, Bo Zhu, Chang Liu, Xiaoran Wang, Man Han, Meng Cao, Fan Xiao, Shengjun Wang, Ke Rui, Liwei Lu
Journal: Inflamm Res
PubMed ID: 36301339
Doi: 10.1007/s00011-022-01660-5
Products & Services: Proteins, Expression, Isolation and Analysis   

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