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Boophilin D1, a Kunitz type protease inhibitor, as a source of inhibitors for the ZIKA virus NS2B-NS3 protease

Authors: Veronica de Moraes Manzato, Camila Di Santo, Ricardo Jose Soares Torquato, Camila Coelho, Gloria Gallo, Leon Hardy, Martin Würtele, Aparecida Sadae Tanaka

Journal: Biochimie

PubMed ID: 37364769

Doi: 10.1016/j.biochi.2023.06.010

Products & Services: Molecular Biology Reagents

Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding

Authors: Erik B Faber, Luxin Sun, Jian Tang, Emily Roberts, Sornakala Ganeshkumar, Nan Wang, Damien Rasmussen, Abir Majumdar, Laura E Hirsch, Kristen John, An Yang, Hira Khalid, Jon E Hawkinson, Nicholas M Levinson, Vargheese Chennathukuzhi, Daniel A Harki, Ernst Schönbrunn, Gunda I Georg

Journal: Nat Commun

PubMed ID: 37270540

Doi: 10.1038/s41467-023-38732-x

Products & Services: Molecular Biology Reagents

Grafting Rhodobacter sphaeroides with red algae Rubisco to accelerate catalysis and plant growth

Authors: Yu Zhou, Laura H Gunn, Rosemary Birch, Inger Andersson, Spencer M Whitney

Journal: Nat Plants

PubMed ID: 37291398

Doi: 10.1038/s41477-023-01436-7

Products & Services: Molecular Biology Reagents

Systematic Mining and Evaluation of the Sesquiterpene Skeletons as High Energy Aviation Fuel Molecules

Authors: Yanglei Huang, Ziling Ye, Xiukun Wan, Ge Yao, Jingyu Duan, Jiajia Liu, Mingdong Yao, Xiang Sun, Zixin Deng, Kun Shen, Hui Jiang, Tiangang Liu

Journal: Adv Sci (Weinh)

PubMed ID: 37271925

Doi: 10.1002/advs.202300889

Products & Services: Molecular Biology Reagents

Glutamine synthetase (GS) knockout (KO) using CRISPR/Cpf1 diversely enhances selection efficiency of CHO cells expressing therapeutic antibodies

Authors: Witsanu Srila, Martina Baumann, Markus Riedl, Kuntalee Rangnoi, Nicole Borth, Montarop Yamabhai

Journal: Sci Rep

PubMed ID: 37380701

Doi: 10.1038/s41598-023-37288-6

Products & Services: Protein and Antibody Isolation

Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3

Authors: Hayarpi Torosyan, Michael D Paul, Antoine Forget, Megan Lo, Devan Diwanji, Krzysztof Pawłowski, Nevan J Krogan, Natalia Jura, Kliment A Verba

Journal: Nat Commun

PubMed ID: 37336883

Doi: 10.1038/s41467-023-38864-0

Products & Services: Gene Synthesis

An Inferred Ancestral CotA Laccase with Improved Expression and Kinetic Efficiency

Authors: Lei Lei, Lijun Zhao, Yiqia Hou, Chen Yue, Pulin Liu, Yanli Zheng, Wenfang Peng, Jiangke Yang

Journal: Int J Mol Sci

PubMed ID: 37446078

Doi: 10.3390/ijms241310901

Products & Services: Recombinant Proteins

Mycobacterium abscessus VapC5 toxin potentiates evasion of antibiotic killing by ribosome overproduction and activation of multiple resistance pathways

Authors: Eduardo A Troian, Heather M Maldonado, Unnati Chauhan, Valdir C Barth, Nancy A Woychik

Journal: Nat Commun

PubMed ID: 37349306

Doi: 10.1038/s41467-023-38844-4

Products & Services: PCR Cloning and Subcloning Plasmid DNA Preparation

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins

Authors: Julie Lavie, Claude Lalou, Walid Mahfouf, Jean-William Dupuy, Aurélie Lacaule, Agata Ars Cywinska, Didier Lacombe, Anne-Marie Duchêne, Anne-Aurélie Raymond, Hamid Reza Rezvani, Richard Patryk Ngondo, Giovanni Bénard

Journal: Cell Rep

PubMed ID: 37267103

Doi: 10.1016/j.celrep.2023.112579

Products & Services: Catalog Peptides

Modularity and diversity of target selectors in Tn7 transposons

Authors: Guilhem Faure, Makoto Saito, Sean Benler, Iris Peng, Yuri I Wolf, Jonathan Strecker, Han Altae-Tran, Edwin Neumann, David Li, Kira S Makarova, Rhiannon K Macrae, Eugene V Koonin, Feng Zhang

Journal: Mol Cell

PubMed ID: 37267947

Doi: 10.1016/j.molcel.2023.05.013

Products & Services: Molecular Biology Reagents