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页码: 40/5233 每页显示数量

Mesothelin-directed protein-drug conjugates for mesothelin-low solid tumor therapy

Authors: Ying Wang, Jiayao Yan, Lin Li, Tianran Chen, Jingyi Guo, Lei Lei, Siwen Wu, Lijing Zhu, Xiaotong Chen, Baorui Liu

Journal: Nature Communications

PubMed ID: 40849430

Doi: 10.1038/s41467-025-63269-6.

Products & Services: Recombinant Proteins

Irreversible furin cleavage site exposure renders immature tick-borne flaviviruses fully infectious

Authors: Jiří Holoubek, Jiří Salát, Milos Matkovic, Petr Bednář, Pavel Novotný, Martin Hradilek, Taťána Majerová, Ebba Rosendal, Luděk Eyer, Andrea Fořtová, Michaela Beránková, Lesley Bell-Sakyi, Anna K. Överby, Andrea Cavalli, Massimiliano Bonomi, Félix A. Rey, Daniel Růžek

Journal: Nature Communications

PubMed ID: 40796726

Doi: 10.1038/s41467-025-62750-6.

Products & Services: PCR Cloning and Subcloning

The cAMP-PKA signaling initiates mitosis by phosphorylating Bora

Authors: Min Zhu, Shinan Zhou, Yingqi Zhang, Qinfu Chen, Xueying Yuan, Long Zhang, Haiyan Yan, Fangwei Wang

Journal: Nature Communications

PubMed ID: 40849432

Doi: 10.1038/s41467-025-63352-y.

Products & Services: Polyclonal Antibody Services

Soluble N-terminal region of prion protein causes rapid neurodegeneration in prion disease

Authors: Runchuan Yan, Yan Zhang, Jingjing Zhang, Xiangyi Zhang, Yue Han, Mengfei Wang, Dan Wang, Shengnan Huang, Wei Liu, Qi Shi, Xiaoping Dong, Wen-Quan Zou, Zhen Li, Jiyan Ma

Journal: SCIENCE ADVANCES

PubMed ID: 40768577

Doi: 10.1126/sciadv.adw6867

Products & Services: Recombinant Antibody Expression

Structural insights into polymerase-catalyzed FAD capping of hepatitis C virus RNA

Authors: De-Ping Wang, Rong Zhao, Wen-Shu Hu, Hai-Ning Li, Ji-Min Cao, Xin Zhou, Ye Xiang

Journal: Nature Communications

PubMed ID: 40775214

Doi: 10.1038/s41467-025-62609-w.

Products & Services: Protein and Antibody Isolation

Quantifying collective interactions in biomolecular phase separation

Authors: Hannes Ausserwöger, Ella de Csilléry, Daoyuan Qian, Georg Krainer, Timothy J Welsh, Tomas Sneideris, Titus M Franzmann, Seema Qamar, Nadia A Erkamp, Jonathon Nixon-Abell, Mrityunjoy Kar, Peter St George-Hyslop, Anthony A Hyman, Simon Alberti, Rohit V Pappu, Tuomas P J Knowles

Journal: Nature Communications

PubMed ID: 40830100

Doi: 10.1038/s41467-025-62437-y.

Optimised modular anti‐FLAG CAR T cells for solid tumor therapy

Authors: Xiaomeng Zhang, Rachel Xu, Dmitry Zorin, Evan G Pappas, Jiawei Tang, Yuchen Bai, Vicky M Qin, Bianca von Scheidt, Ruihong Huang, Weronika Kulakowska, Charbel Darido, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney

Journal: Clinical & Translational Immunology

PubMed ID: 40851786

Doi: 10.1002/cti2.70046

Products & Services: Recombinant Proteins Gene Synthesis

A receptor antagonist counterbalances multiple systemin phytocytokines in tomato

Authors: Lei Wang, Louis-Philippe Maier, Nga Pham, Yan L Wang, Xu Wang, Andreas Schaller, Judith Fliegmann, Matthias Erb, Thomas Boller, Georg Felix

Journal: Cell

PubMed ID: 40845839

Doi: 10.1016/j.cell.2025.07.044

Products & Services: Peptide Synthesis

Highly scalable prefusion-stabilized RSV F vaccine with enhanced immunogenicity and robust protection

Authors: Qingrui Huang, Qingyun Lang, Yao Li, Fengjie Wang, Xiaonan Han, Ling Luo, Xiaomin Duan, Xuerong Cao, Yue Wang, Yu Bai, Yaxin Song, Yanpeng Xu, Lianlian Bian, Chenyan Gao, Linqing Zhao, Jinghua Yan

Journal: Nature Communications

PubMed ID: 40841372

Doi: 10.1038/s41467-025-63084-z.

Products & Services: Gene Synthesis

LYMTACs:chimeric small molecules repurpose lysosomal membrane proteins for target protein relocalization and degradation

Authors: Dhanusha A Nalawansha, Georgios Mazis, Gitte Husemoen, Kate S Ashton, Weixian Deng, Ryan P Wurz, Anh T Tran, Brian A Lanman, Jiansong Xie, Robert G Guenette, Shiqian Li, Christopher E Smith, Suresh Archunan, Manoj K Agnihotram, Arghya Sadhukhan, Rajiv Kapoor, Chris Wilde, Sajjan Koirala, Felipe De Sousa E Melo, Patrick Ryan Potts

Journal: Nature Communications

PubMed ID: 40841368

Doi: 10.1038/s41467-025-63128-4.

Products & Services: Custom Vector Construction