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Binding and transport of LPS occurs through the coordinated combination of an array of sites across the entire Escherichia coli LPS transport protein LptA
Authors: Kathryn M Schultz, John R Schneider, Matthew A Fischer, Nicholas P Cina, Molly O Riegert, Dara W Frank, Candice S Klug
Journal: Protein Sci
PubMed ID: 37417889
Doi: 10.1002/pro.4724
Products & Services: Gene Synthesis   
Optimization of an alum-anchored clinical HIV vaccine candidate
Authors: Kristen A Rodrigues, Christopher A Cottrell, Jon M Steichen, Bettina Groschel, Wuhbet Abraham, Heikyung Suh, Yash Agarwal, Kaiyuan Ni, Jason Y H Chang, Parisa Yousefpour, Mariane B Melo, William R Schief, Darrell J Irvine
Journal: npj Vaccines
PubMed ID: 37573422
Doi: 10.1038/s41541-023-00711-0
Products & Services: Recombinant Proteins   
Evaluating the effect of food components on the digestion of dietary nucleic acids in human gastric juice in vitro
Authors: Yanfang Zhang, Jingyi Dong, Jingxian Chen, Xiaoming Pan
Journal: Food Sci Nutr
PubMed ID: 37823154
Doi: 10.1002/fsn3.3599
Products & Services: Custom DNA/RNA Oligos   
Toward non-factor therapy in hemophilia: an antithrombin insensitive Gla-domainless factor Xa as tissue factor pathway inhibitor bait
Authors: Marie-Claire Dagher, Atanur Ersayin, Landry Seyve, Mathieu Castellan, Cyril Moreau, Luc Choisnard, Nicole Thielens, Raphaël Marlu, Benoît Polack, Aline Thomas
Journal: Res Pract Thromb Haemost
PubMed ID: 37841511
Doi: 10.1016/j.rpth.2023.102175
Products & Services: Combinatorial DNA Libraries   
Immobilization of α-transglucosidase on silica-coated magnetic nanoparticles and its application for production of isomaltooligosaccharide from the potato peel
Authors: Rohit Maurya, Usman Ali, Sunaina Kaul, Raja Bhaiyya, Ravindra Pal Singh, Koushik Mazumder
Journal: Sci Rep
PubMed ID: 37543692
Doi: 10.1038/s41598-023-38266-8
Products & Services: Molecular Biology Reagents   
CircMIB2 therapy can effectively treat pathogenic infection by encoding a novel protein
Authors: Weiwei Zheng, Linchao Wang, Shang Geng, Liyuan Yang, Xing Lv, Shiying Xin, Tianjun Xu
Journal: Cell Death Dis
PubMed ID: 37652905
Doi: 10.1038/s41419-023-06105-3
Products & Services: Custom RNAi Services   
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1
Authors: Jun-Qi Luo, Tao-Wei Yang, Jun Wu, Hou-Hua Lai, Li-Bin Zou, Wen-Bin Chen, Xu-Min Zhou, Dao-Jun Lv, Sheng-Ren Cen, Zi-Ning Long, Yi-You Mao, Peng-Xiang Zheng, Xiao-Hong Su, Zhi-Yong Xian, Fang-Peng Shu, Xiang-Ming Mao
Journal: Cell Death Dis
PubMed ID: 37542027
Doi: 10.1038/s41419-023-06007-4
Products & Services: Catalog Antibody   
The SlWRKY6-SlPROPEP-SlPep module confers tomato resistance to Phytophthora infestans
Authors: Ruirui Yang , Jie Liu , Zhicheng Wang , Lei Zhao , Tingting Xue , Jun Meng , Yushi Luan
Journal: Scientia Horticulturae
Doi: 10.1016/j.scienta.2023.112117
Products & Services: Peptide Synthesis   
Mechanosensitive accumulation of non-muscle myosin IIB during mitosis requires its translocation activity
Authors: Chao Wang , Jingjing Ding , Qiaodong Wei , Shoukang Du , Xiaobo Gong , Ting Gang Chew
Journal: iScience .
PubMed ID: 37720093
Doi: 10.1016/j.isci.2023.107773
Using a synthetic machinery to improve carbon yield with acetylphosphate as the core
Authors: Likun Guo , Min Liu , Yujia Bi , Qingsheng Qi, Mo Xian , Guang Zhao
Journal: Nat Commun .
PubMed ID: 37648707
Doi: 10.1038/s41467-023-41135-7
Products & Services: Codon Optimization   
Peripheral substitution effects on unnatural base pairs: A case of brominated TPT3 to enhance replication fidelity
Authors: Bianbian Huo, Chao Wang, Xiaoqi Hu, Honglei Wang, Gongming Zhu, Anlian Zhu, Lingjun Li
Journal: Bioorg Chem
PubMed ID: 37683537
Doi: 10.1016/j.bioorg.2023.106827
Context-dependent role of Pho binding sites in Polycomb complex recruitment in Drosophila
Authors: Janet Lesley Brown, Joshua D Price, Maksim Erokhin, Judith A Kassis
Journal: Genetics
PubMed ID: 37216193
Doi: 10.1093/genetics/iyad096
Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting
Authors: Stefania Torino, Mugdha Dhurandhar, Annelore Stroobants, Raf Claessens, Rouslan G Efremov
Journal: Nat Methods
PubMed ID: 37592181
Doi: 10.1038/s41592-023-01967-z
Enhancement of Neutralization Responses through Sequential Immunization of Stable Env Trimers Based on Consensus Sequences from Select Time Points by Mimicking Natural Infection
Authors: Mingming Wan, Xiao Yang, Jie Sun, Elena E Giorgi, Xue Ding, Yan Zhou, Yong Zhang, Weiheng Su, Chunlai Jiang, Yaming Shan, Feng Gao
Journal: Int J Mol Sci
PubMed ID: 37628824
Doi: 10.3390/ijms241612642
Products & Services: Gene Synthesis   
Rice-produced classical swine fever virus glycoprotein E2 with herringbone-dimer design to enhance immune responses
Authors: Qianru Xu, Fanshu Ma, Daichang Yang, Qingmei Li, Liming Yan, Jiquan Ou, Longxian Zhang, Yunchao Liu, Quan Zhan, Rui Li, Qiang Wei, Hui Hu, Yanan Wang, Xueyang Li, Shenli Zhang, Jifei Yang, Shujun Chai, Yongkun Du, Li Wang, Erqin Zhang, Gaiping Zhang
Journal: Plant Biotechnol J
PubMed ID: 37572354
Doi: 10.1111/pbi.14152
Products & Services: Gene Synthesis   
Nanoparticles carrying paclitaxel and anti-miR-221 for breast cancer therapy triggered by ultrasound
Authors: Libo Zhang, Zhen Ren, Jinhui Lü, Xinhai Mo, Jie Lin, Ya Li, Wenjing Ma, Pengfei Liu, Yajing Shen, Qian Zhao, Lu Qian, Xiaoxin Cheng, Zuoren Yu, Bo Zhang
Journal: Cell Death Discov
PubMed ID: 37582832
Doi: 10.1038/s41420-023-01594-9
Products & Services: Custom DNA/RNA Oligos   
Precision Genome Engineering in Based on a Broad-Host-Range Vector and CRISPR-Cas9 Technology
Authors: Alex Gussak, Maria Laura Ferrando, Mels Schrama, Peter van Baarlen, Jerry Mark Wells
Journal: ACS Synth Biol
PubMed ID: 37602730
Doi: 10.1021/acssynbio.3c00110
Products & Services: Peptide Synthesis   
Structure and design of Langya virus glycoprotein antigens
Authors: Zhaoqian Wang, Matthew McCallum, Lianying Yan, William Sharkey, Young-Jun Park, Ha V Dang, Moushimi Amaya, Ashley Person, Christopher C Broder, David Veesler
Journal: biorxiv
PubMed ID: 37645760
Doi: 10.1101/2023.08.20.554025
Products & Services: ORF cDNA Clones/MolecularCloud   
Structural mechanism of synergistic targeting of the nucleosome by PU1 and C/EBPα
Authors: Tengfei Lian, Ruifang Guan, Bing-Rui Zhou, Yawen Bai
Journal: biorxiv
PubMed ID: 37790476
Doi: 10.1101/2023.08.25.554718
Products & Services: Gene Synthesis   
Stromal cell-derived factor-1 downregulation contributes to neuroprotection mediated by CXC chemokine receptor 4 interactions after intracerebral hemorrhage in rats
Authors: Yu Wu, Zhuwei Zhang, Xiaoou Sun, Jing Wang, Haitao Shen, Xue Sun, Zhong Wang
Journal: CNS Neurosci Ther
PubMed ID: 37614198
Doi: 10.1111/cns.14400
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Origin of the OAS–RNase L innate immune pathway before the rise of jawed vertebrates via molecular tinkering
Authors: Lingyu Chu , Zhen Gong , Wenqiang Wang , Guan-Zhu Han
Journal: Proceedings of the National Academy of Sciences of the United States of America
PubMed ID: 37487089
Doi: 10.1073/pnas.2304687120
Products & Services: Codon Optimization   
Multimodal, broadly neutralizing antibodies against SARS-CoV-2 identified by high-throughput native pairing of BCRs from bulk B cells
Authors: Gladys J Keitany , Benjamin E R Rubin , Meghan E Garrett , Andrea Musa , Jeff Tracy , Yu Liang , Peter Ebert , Amanda J Moore , Jonathan Guan , Erica Eggers , Ninnia Lescano , Ryan Brown , Adria Carbo , Hussein Al-Asadi , Travers Ching , Austin Day , Rebecca Harris , Charles Linkem , Dimitry Popov , Courtney Wilkins , Lianqu Li , Jiao Wang , Chuanxin Liu , Li Chen , Jennifer N Dines , Caroline Atyeo , Galit Alter , Lance Baldo , Anna Sherwood , Bryan Howie , Mark Klinger , Erik Yusko , Harlan S Robins , Sharon Benzeno , Amy E Gilbert
Journal: Cell Chem Biol .
PubMed ID: 37586370
Doi: 10.1016/j.chembiol.2023.07.011
A near-infrared fluorescence-enhancing plasmonic biosensing microarray identifies soluble PD-L1 and ICAM-1 as predictive checkpoint biomarkers for cancer immunotherapy
Authors: Zhijun Lin, Mengyao Liu, Wei Xing, Fenghua Wang, Hongxia Zhang, Xiaoli Wei, Hans Schmitthenner, Xi Xie, Xiaojun Xia, Jiang Yang
Journal: Biosens Bioelectron
PubMed ID: 37683502
Doi: 10.1016/j.bios.2023.115633
The viral fitness and intrinsic pathogenicity of dominant SARS-CoV-2 Omicron sublineages BA1, BA2, and BA5
Authors: Huiping Shuai, Jasper Fuk-Woo Chan, Bingjie Hu, Yue Chai, Chaemin Yoon, Huan Liu, Yuanchen Liu, Jialu Shi, Tianrenzheng Zhu, Jing-Chu Hu, Ye-Fan Hu, Yuxin Hou, Xiner Huang, Terrence Tsz-Tai Yuen, Yang Wang, Jinjin Zhang, Yao Xia, Lin-Lei Chen, Jian-Piao Cai, Anna Jinxia Zhang, Shuofeng Yuan, Jie Zhou, Bao-Zhong Zhang, Jian-Dong Huang, Kwok-Yung Yuen, Kelvin Kai-Wang To, Hin Chu
Journal: EBioMedicine
PubMed ID: 37579626
Doi: 10.1016/j.ebiom.2023.104753
Anti-SARS-CoV-2 Antibody Level Is Associated with a History of COVID-19 Infection and mRNA Vaccination in Patients with Diabetes
Authors: Is Asma'ul Haq Hataul, Nanny Natalia M Soetedjo, Josephine Debora, Marita Restie Tiara, Hofiya Djauhari, Evan Susandi, Bachti Alisjahbana, Rudi Wisaksana, Hikmat Permana
Journal: Vaccines (Basel)
PubMed ID: 37766101
Doi: 10.3390/vaccines11091424
ABBV-184: A Novel Survivin-specific TCR/CD3 Bispecific T-cell Engager is Active against Both Solid Tumor and Hematologic Malignancies
Authors: Adam S Chervin, Jennifer D Stone, Iwona Konieczna, Kelly M Calabrese, Ningyan Wang, Dipica Haribhai, Feng Dong, Michael K White, Luis E Rodriguez, Gail T Bukofzer, Paul A Ellis, Cormac Cosgrove, Claudie Hecquet, Jerry D Clarin, Joann P Palma, Edward B Reilly
Journal: Mol Cancer Ther
PubMed ID: 37294945
Doi: 10.1158/1535-7163.MCT-22-0770
Products & Services: Peptide Synthesis   
Expression analysis, clinical significance and potential function of PLXNB2 in acute myeloid leukaemia
Authors: Zhibo Guo, Dan Guo, Desheng Kong, Sicheng Bian, Linlin Zhao, Qi Li, Leilei Lin, Jiali Hao, Lili Sun, Yinghua Li
Journal: Mol Biol Rep
PubMed ID: 37632633
Doi: 10.1007/s11033-023-08721-w
Products & Services: Molecular Biology Reagents   
NLRC4 promotes the cGAS-STING signaling pathway by facilitating CBL-mediated K63-linked polyubiquitination of TBK1
Authors: Rongzhao Zhang, Wenxian Yang, Huifang Zhu, Jingbo Zhai, Mengzhou Xue, Chunfu Zheng
Journal: J Med Virol
PubMed ID: 37537877
Doi: 10.1002/jmv.29013
Products & Services: Molecular Biology Reagents   
Biosynthesis of High-Active Hemoproteins by the Efficient Heme-Supply Pichia Pastoris Chassis
Authors: Fei Yu, Xinrui Zhao, Jingwen Zhou, Wei Lu, Jianghua Li, Jian Chen, Guocheng Du
Journal: Adv Sci (Weinh)
PubMed ID: 37649147
Doi: 10.1002/advs.202302826
Products & Services: Molecular Biology Reagents   
Obtaining high yield recombinant Enterococcus faecium nicotinate nucleotide adenylyltransferase for X-ray crystallography and biophysical studies
Authors: Olamide Jeje, Ramesh Pandian, Yasien Sayed, Ikechukwu Achilonu
Journal: Int J Biol Macromol
PubMed ID: 37544558
Doi: 10.1016/j.ijbiomac.2023.126066
Products & Services: Molecular Biology Reagents   
Gene co-option, duplication and divergence of cement proteins underpin the evolution of bioadhesives across barnacle life histories
Authors: Yue Him Wong, Niklas Dreyer, HaoCheng Liu, Yi Lan, Jamie J Chen, Jin Sun, Wei-Peng Zhang, Pei-Yuan Qian, Benny K K Chan
Journal: Mol Ecol
PubMed ID: 37584177
Doi: 10.1111/mec.17084
Correction to: An Immunoinformatics-Based Study of Mycobacterium tuberculosis Region of Difference-2 Uncharacterized Protein (Rv1987) as a Potential Subunit Vaccine Candidate for Preliminary Ex Vivo Analysis
Authors: Aregitu Mekuriaw Arega, Ajit Kumar Dhal, Kali Prasad Pattanaik, Sasmita Nayak, Rajani Kanta Mahapatra
Journal: Appl Biochem Biotechnol
PubMed ID: 37552364
Doi: 10.1007/s12010-023-04668-7
Products & Services: Gene Synthesis   
NvPrdm14d-expressing neural progenitor cells contribute to non-ectodermal neurogenesis in Nematostella vectensis
Authors: Quentin I B Lemaître, Natascha Bartsch, Ian U Kouzel, Henriette Busengdal, Gemma Sian Richards, Patrick R H Steinmetz, Fabian Rentzsch
Journal: Nat Commun
PubMed ID: 37563174
Doi: 10.1038/s41467-023-39789-4
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Role of the CagY antenna projection in Cag type IV secretion system activity
Authors: Sirena C Tran, Mark S McClain, Timothy L Cover
Journal: Infect Immun
PubMed ID: 37638724
Doi: 10.1128/iai.00150-23
Products & Services: Plasmid DNA Preparation   
The brassinosteroid-responsive protein OCTOPUS is a novel regulator of immune signaling
Authors: Kaitlyn N Greenwood, Courtney L King, Isabella Melena, Katherine A Stegemann, Maura Donnelly, Anna Childers, Raegan Mozal, Carina A Collins, Benjamin J Spears
Journal: Plant Direct
PubMed ID: 37638229
Doi: 10.1002/pld3.524
Products & Services: Peptide Synthesis   
SARS-CoV-2 ORF8 accessory protein is a virulence factor
Authors: M Bello-Perez, J Hurtado-Tamayo, A Z Mykytyn, M M Lamers, R Requena-Platek, D Schipper, D Muñoz-Santos, J Ripoll-Gómez, A Esteban, P J Sánchez-Cordón, L Enjuanes, B L Haagmans, I Sola
Journal: MBio
PubMed ID: 37623322
Doi: 10.1128/mbio.00451-23
Products & Services: Stable Cell Lines   
Rapid and ultrasensitive detection of mpox virus using CRISPR/Cas12b-empowered graphene field-effect transistors
Authors: LiWang;ChangXu;ShaohuiZhang ;ShangChen;HaoWang;ZhaojunDuan;OmarA.Al-Hartomy ;SwelmWageh;XiaoshaWen;YiLiu;YiLin;HuijiePu;ZhongjianXie;QuanLiu;HanZhang;DixianLuo
Journal: Applied Physics Reviews
Doi: 10.1063/5.0142494
Products & Services: Gene Synthesis   
Flow-cytometric cell sorting coupled with UV mutagenesis for improving pectin lyase expression
Authors: Ke Fang , Jun Ma , Xinyu Wang, Ziting Xu , Ziyang Zhang , Piwu Li , Ruiming Wang, Junqing Wang, Chuying Sun and Ziyang Dong
Journal: Frontiers in bioengineering and biotechnology
Doi: 10.3389/fbioe.2023.1251342
Products & Services: PCR Cloning and Subcloning   
Backbone-Installed Split Intein-Assisted Ligation for the Chemical Synthesis of Mirror-Image Proteins
Authors: Baochang Zhang, Yupeng Zheng, Guochao Chu, Xiangyu Deng, Tongyue Wang, Weiwei Shi, Yongkang Zhou, Shan Tang , Ji-Shen Zheng , Lei Liu
Journal: Angew Chem Int Ed Engl
PubMed ID: 37357888
Doi: 10.1002/anie.202306270
Products & Services: Custom Vector Construction   
Enhancement of β-carotene content in Chlamydomonas reinhardtii by expressing bacterium-driven lycopene β-cyclase
Authors: Danqiong Huang , Chenglong Liu , Mingshan Su , Zhiyong Zeng , Chaogang Wang , Zhangli Hu , Sulin Lou , Hui Li
Journal: Biotechnol Biofuels Bioprod .
PubMed ID: 37573357
Doi: 10.1186/s13068-023-02377-1
Products & Services: Gene Synthesis   
Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing
Authors: Lenong Li, Xubiao Peng, Mansoor Batliwala, Marlene Bouvier
Journal: Nat Commun
PubMed ID: 37596268
Doi: 10.1038/s41467-023-40736-6
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Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation
Authors: Frederic Morales-Paytuví, Alba Fajardo, Carles Ruiz-Mirapeix, James Rae, Francesc Tebar, Marta Bosch, Carlos Enrich, Brett M Collins, Robert G Parton, Albert Pol
Journal: J Cell Biol
PubMed ID: 37526691
Doi: 10.1083/jcb.202204020
Interchangeability of the Assays Used to Assess the Activity of Anti-SARS-CoV-2 Monoclonal Antibodies
Authors: Brady T Hickerson, Alexey M Khalenkov, Tao Xie, David M Frucht, Dorothy E Scott, Natalia A Ilyushina
Journal: Viruses
PubMed ID: 37632039
Doi: 10.3390/v15081698
Variation in microbial feature perception in the Rutaceae family with immune receptor conservation in citrus
Authors: Jessica Trinh, Tianrun Li, Jessica Y Franco, Tania Y Toruño, Danielle M Stevens, Shree P Thapa, Justin Wong, Rebeca Pineda, Emmanuel Ávila de Dios, Tracy L Kahn, Danelle K Seymour, Chandrika Ramadugu, Gitta L Coaker
Journal: Plant Physiol
PubMed ID: 37144828
Doi: 10.1093/plphys/kiad263
Products & Services: Peptide Synthesis   
Id-neoantigen vaccine induces therapeutic CD8 T cells against multiple myeloma: H chain-loss escapees cause FLC MM
Authors: Marita Westhrin, Jana Blazevski, Ana Textor, Pegah Abdollahi, Ramakrishna Prabhu Gopalakrishnan, Linda Thuy Ngo, Peter Olaf Hofgaard, Julia Heinzelbecker, Sonja Bobic, Even Fossum, Heidi Cecilie Larsen Spång, Ranveig Braathen, Bjarne Bogen
Journal: J Immunother Cancer
PubMed ID: 37607769
Doi: 10.1136/jitc-2023-006944
CircRNA-CIRH1A Promotes the Development of Osteosarcoma by Regulating PI3K/AKT and JAK2/STAT3 Signaling Pathways
Authors: Meng Zhang, Xiang Wang, Jianfeng Zhao, Jizhou Yan, Xiaodan He, Danxia Qin, Fang Liang, Kai Tong, Jianjian Wang
Journal: Mol Biotechnol
PubMed ID: 37608076
Doi: 10.1007/s12033-023-00812-0
Products & Services: Custom DNA/RNA Oligos   
Stabilisation of the RirA [4Fe-4S] cluster results in loss of iron-sensing function
Authors: Elizabeth Gray, Melissa Y Y Stewart, Libby Hanwell, Jason C Crack, Rebecca Devine, Clare E M Stevenson, Anne Volbeda, Andrew W B Johnston, Juan C Fontecilla-Camps, Matthew I Hutchings, Jonathan D Todd, Nick E Le Brun
Journal: Chem Sci
PubMed ID: 37736639
Doi: 10.1039/d3sc03020b
Products & Services: Gene Synthesis   
Neutrophil-Mediated Tumor-Targeting Delivery System of Oncolytic Bacteria Combined with ICB for Melanoma Lung Metastasis Therapy
Authors: Lina Liu, Wenjie Xin, Qiang Li, Baolian Huang, Te Yin, Siqi Hua, Chen Yang, Chen Chen, Chao Han, Zichun Hua
Journal: Adv Sci (Weinh)
PubMed ID: 37565362
Doi: 10.1002/advs.202301835
Products & Services: Gene Synthesis   
Soluble SARS-CoV-2 RBD and human ACE2 peptidase domain produced in Drosophila S2 cells show functions evoking virus-cell interface
Authors: Federico Carrión, Florencia Rammauro, Natalia Olivero-Deibe, Martín Fló, María Magdalena Portela, Analía Lima, Rosario Durán, Otto Pritsch, Sergio Bianchi
Journal: Protein Sci
PubMed ID: 37405395
Doi: 10.1002/pro.4721
Products & Services: Gene Synthesis   
Garlic-derived exosome-like nanovesicles as a hepatoprotective agent alleviating acute liver failure by inhibiting CCR2/CCR5 signaling and inflammation
Authors: Xin Zhao, Fang Yin, Luoqin Fu, Yingyu Ma, Luyi Ye, Yilin Huang, Weijiao Fan, Wenxue Gao, Yu Cai, Xiaozhou Mou
Journal: Biomater Adv
PubMed ID: 37717364
Doi: 10.1016/j.bioadv.2023.213592
Products & Services: PCR Cloning and Subcloning   
Subtilisin 3 production from Microsporum canis is independent of keratin substrate availability
Authors: Alex E Moskaluk, Lauren Darlington, Sue VandeWoude
Journal: J Basic Microbiol
PubMed ID: 37551993
Doi: 10.1002/jobm.202300125
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN
Authors: Robbert J de Haas, Natalie Brunette, Alex Goodson, Justas Dauparas, Sue Y Yi, Erin C Yang, Quinton Dowling, Hannah Nguyen, Alex Kang, Asim K Bera, Banumathi Sankaran, Renko de Vries, David Baker, Neil P King
Journal: biorxiv
PubMed ID: 37577478
Doi: 10.1101/2023.08.04.551935
Products & Services: Molecular Biology Reagents   
Structure of Orthoreovirus RNA Chaperone σNS, a Component of Viral Replication Factories
Authors: Boyang Zhao, Liya Hu, Soni Kuandal, Neetu Neetu, Christopher Lee, Xayathed Somoulay, Banumathi Sankaran, Gwen M Taylor, Terence S Dermody, B V Venkataram Prasad
Journal: biorxiv
PubMed ID: 37577609
Doi: 10.1101/2023.07.31.551319
Non-IgE-reactive allergen peptides deteriorate the skin barrier in house dust mite-sensitized atopic dermatitis patients
Authors: Karin Pfisterer, Matthias Wielscher, David Samardzic, Pauline Weinzettl, Dorte Symmank, Lisa E Shaw, Raffaela Campana, Huey-Jy Huang, Matthias Farlik, Christine Bangert, Susanne Vrtala, Rudolf Valenta, Wolfgang Weninger
Journal: Front Cell Dev Biol
PubMed ID: 37675143
Doi: 10.3389/fcell.2023.1240289
Products & Services: Molecular Biology Reagents   
Nona-Arginine Mediated Anti-E6 ShRNA Delivery Suppresses the Growth of Hela Cells in vitro
Authors: Razieh Taghizadeh Pirposhteh, Ehsan Arefian, Arash Arashkia, Nasir Mohajel
Journal: Iran Biomed J
PubMed ID: 37978985
Doi: 10.52547/ibj.3963
Products & Services: Molecular Biology Reagents   
Synergistic Screening of Peptide-Based Biotechnological Drug Candidates for Neurodegenerative Diseases Using Yeast Display and Phage Display
Authors: Cemile Elif Özçelik, Özge Beğli, Ahmet Hınçer, Recep Erdem Ahan, Mehmet Seçkin Kesici, Oğuzhan Oğuz, Talip Serkan Kasırga, Salih Özçubukçu, Urartu Özgür Şafak Şeker
Journal: ACS Chem Neurosci
PubMed ID: 37638647
Doi: 10.1021/acschemneuro.3c00248
A mechanistic insight for the biosynthesis of N,N-dimethyltryptamine: An ONIOM theoretical approach
Authors: Lucas Pinheiro Coutinho, Sérgio Ruschi Bergamachi Silva, Pedro de Lima-Neto, Norberto de Kássio Vieira Monteiro
Journal: Biochem Biophys Res Commun
PubMed ID: 37640000
Doi: 10.1016/j.bbrc.2023.08.043
Products & Services: PCR Cloning and Subcloning   
Sucrose-induced hyperglycemia dysregulates intestinal zinc metabolism and integrity: risk factors for chronic diseases
Authors: Samuel Blake Mitchell, Yu-Han Hung, Trista Lee Thorn, Jiaqi Zou, Filiz Baser, Sukru Gulec, Celeste Cheung, Tolunay Beker Aydemir
Journal: Front Nutr
PubMed ID: 37637953
Doi: 10.3389/fnut.2023.1220533
Products & Services: Monoclonal Antibody Services   
Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair
Authors: Nikolaos Parisis, Pablo D Dans, Muhammad Jbara, Balveer Singh, Diane Schausi-Tiffoche, Diego Molina-Serrano, Isabelle Brun-Heath, Denisa Hendrychová, Suman Kumar Maity, Diana Buitrago, Rafael Lema, Thiziri Nait Achour, Simona Giunta, Michael Girardot, Nicolas Talarek, Valérie Rofidal, Katerina Danezi, Damien Coudreuse, Marie-Noëlle Prioleau, Robert Feil, Modesto Orozco, Ashraf Brik, Pei-Yun Jenny Wu, Liliana Krasinska, Daniel Fisher
Journal: Nat Commun
PubMed ID: 37607906
Doi: 10.1038/s41467-023-40843-4
Products & Services: Custom DNA/RNA Oligos   
Structure, catalysis, chitin transport, and selective inhibition of chitin synthase
Authors: Dan-Dan Chen, Zhao-Bin Wang, Le-Xuan Wang, Peng Zhao, Cai-Hong Yun, Lin Bai
Journal: Nat Commun
PubMed ID: 37553334
Doi: 10.1038/s41467-023-40479-4
Products & Services: Custom DNA/RNA Oligos   
Anti-Tumor Immunity Induced by a Ternary Membrane System Derived From Cancer Cells, Dendritic Cells, and Bacteria
Authors: He Ren , Jiexin Li , Jingyu Zhang , Jingang Liu , Xingyue Yang , Nan Zhang , Qian Qiu , Dan Li , Yue Yu , Xiaofeng Liu , Jonathan F Lovell , Yumiao Zhang
Journal: Small .
PubMed ID: 37603007
Doi: 10.1002/smll.202302756
Products & Services: Recombinant Proteins   
Performance upgrade of a microbial explosives' sensor strain by screening a high throughput saturation library of a transcriptional regulator
Authors: Lidor David, Etai Shpigel, Itay Levin, Shaked Moshe, Lior Zimmerman, Shilat Dadon-Simanowitz, Benjamin Shemer, Shon A Levkovich, Liraz Larush, Shlomo Magdassi, Shimshon Belkin
Journal: Comput Struct Biotechnol J
PubMed ID: 37701016
Doi: 10.1016/j.csbj.2023.08.017
A conserved family of immune effectors cleaves cellular ATP upon viral infection
Authors: Francois Rousset, Erez Yirmiya, Shahar Nesher, Alexander Brandis, Tevie Mehlman, Maxim Itkin, Sergey Malitsky, Adi Millman, Sarah Melamed, Rotem Sorek
Journal: Cell
PubMed ID: 37595565
Doi: 10.1016/j.cell.2023.07.020
The promoting effect of modified Dioscorea pills on vascular remodeling in chronic cerebral hypoperfusion via the Ang/Tie signaling pathway
Authors: Guiying Kuang, Zhigang Shu, Chunli Zhu, Hongbing Li, Cheng Zhang
Journal: Transl Neurosci
PubMed ID: 37635842
Doi: 10.1515/tnsci-2022-0302
Design of an alternate antibody fragment format that can be produced in the cytoplasm of Escherichia coli
Authors: Aatir A Tungekar, Lloyd W Ruddock
Journal: Sci Rep
PubMed ID: 37648872
Doi: 10.1038/s41598-023-41525-3
Products & Services: Molecular Biology Reagents   
A potent and durable malaria transmission-blocking vaccine designed from a single-component 60-copy Pfs230D1 nanoparticle
Authors: Nichole D Salinas, Rui Ma, Thayne H Dickey, Holly McAleese, Tarik Ouahes, Carole A Long, Kazutoyo Miura, Lynn E Lambert, Niraj H Tolia
Journal: npj Vaccines
PubMed ID: 37596283
Doi: 10.1038/s41541-023-00709-8
Products & Services: DNA Sequencing   
TRIM5α restricts poxviruses and is antagonized by CypA and the viral protein C6
Authors: Yiqi Zhao, Yongxu Lu, Samuel Richardson, Meghna Sreekumar, Jonas D Albarnaz, Geoffrey L Smith
Journal: Nature
PubMed ID: 37558876
Doi: 10.1038/s41586-023-06401-0
Products & Services: Plasmid DNA Preparation   
Heterologous Expression and Partial Characterization of a Putative Opine Dehydrogenase from a Metagenomic Sequence of Desulfohalobium retbaense
Authors: Nevena Kaličanin, Ana Marija Balaž, Olivera Prodanović, Radivoje Prodanović
Journal: Chembiochem
PubMed ID: 37531452
Doi: 10.1002/cbic.202300414
Products & Services: Molecular Biology Reagents   
Sm-like protein Rof inhibits transcription termination factor ρ by binding site obstruction and conformational insulation
Authors: Nelly Said, Mark Finazzo, Tarek Hilal, Bing Wang, Tim Luca Selinger, Daniela Gjorgjevikj, Irina Artsimovitch, Markus C Wahl
Journal: biorxiv
PubMed ID: 37693585
Doi: 10.1101/2023.08.30.555460
Mining and Characterization of Indolethylamine N‑Methyltransferases in Amphibian Toad Bufo gargarizans
Authors: An-An Zhang , Qing-Li He , Qunfei Zhao
Journal: Biochemistry .
PubMed ID: 37490721
Doi: 10.1021/acs.biochem.3c00229
Products & Services: Codon Optimization   
Development of a novel method for diagnosis of fasciolosis based on cathepsin L7 in ruminants
Authors: Jing-Zhi Gong, Yi-Min Fan, Wanzhe Yuan, Ming Pan, Dandan Liu, Jian-Ping Tao, Si-Yang Huang
Journal: Vet Parasitol
PubMed ID: 37657153
Doi: 10.1016/j.vetpar.2023.110021
In skeletal muscle and neural crest cells, SMCHD1 regulates biological pathways relevant for Bosma syndrome and facioscapulohumeral dystrophy phenotype
Authors: Camille Laberthonnière, Mégane Delourme, Raphaël Chevalier, Camille Dion, Benjamin Ganne, David Hirst, Leslie Caron, Pierre Perrin, José Adélaïde, Max Chaffanet, Shifeng Xue, Karine Nguyen, Bruno Reversade, Jérôme Déjardin, Anaïs Baudot, Jérôme D Robin, Frédérique Magdinier
Journal: Nucleic Acids Res
PubMed ID: 37334829
Doi: 10.1093/nar/gkad523
Nanograms of SARS-CoV-2 spike protein delivered by exosomes induce potent neutralization of both delta and omicron variants
Authors: Mafalda Cacciottolo, Yujia Li, Justin B Nice, Michael J LeClaire, Ryan Twaddle, Ciana L Mora, Stephanie Y Adachi, Meredith Young, Jenna Angeles, Kristi Elliott, Minghao Sun
Journal: PLoS ONE
PubMed ID: 37607200
Doi: 10.1371/journal.pone.0290046
Products & Services: Molecular Biology Reagents   
Mass-produced gram-negative bacterial outer membrane vesicles activate cancer antigen-specific stem-like CD8 T cells which enables an effective combination immunotherapy with anti-PD-1
Authors: Solchan Won, Changjin Lee, Seoyoon Bae, Jaemin Lee, Dongsic Choi, Min-Gang Kim, Sunghyun Song, Jaewook Lee, Eunhye Kim, HaYoung Shin, Anita Basukala, Tae Ryong Lee, Dong-Sup Lee, Yong Song Gho
Journal: J Extracell Vesicles
PubMed ID: 37563797
Doi: 10.1002/jev2.12357
Products & Services: Molecular Biology Reagents   
Structural and dynamic heterogeneity in associative networks formed by artificially engineered protein polymers
Authors: Ameya Rao, Bradley D Olsen
Journal: Soft Matter
PubMed ID: 37560814
Doi: 10.1039/d3sm00150d
Products & Services: Molecular Biology Reagents   
Cell-free transcription-translation system: a dual read-out assay to characterize riboswitch function
Authors: Jasleen Kaur Bains, Nusrat Shahin Qureshi, Betül Ceylan, Anna Wacker, Harald Schwalbe
Journal: Nucleic Acids Res
PubMed ID: 37409574
Doi: 10.1093/nar/gkad574
Products & Services: Plasmid DNA Preparation   
Ester Bond: Chemically Labile Yet Mechanically Stable
Authors: Hai Lei, Quan Ma, Zhangxia Wang, Di Zhang, Xiaoyu Huang, Meng Qin, Haibo Ma, Wei Wang, Yi Cao
Journal: ACS Nano
PubMed ID: 37646337
Doi: 10.1021/acsnano.3c03807
Products & Services: Gene Synthesis   
The Expansin Gene Is a Direct Target of CsLOB1 in Citrus
Authors: Reinaldo Rodrigues de Souza-Neto, Fernanda Nogales da Costa Vasconcelos, Doron Teper, Isis Gabriela Barbosa Carvalho, Marco Aurelio Takita, Celso Eduardo Benedetti, Nian Wang, Alessandra Alves de Souza
Journal: Phytopathology
PubMed ID: 36825333
Doi: 10.1094/PHYTO-11-22-0424-R
Products & Services: Synthetic sgRNA and crRNA Service   
Rapid Determination of the Topology of Oligomeric α-Helical Membrane Proteins by Water- and Lipid-Edited Methyl NMR
Authors: Iva Sučec, Nadia El Mammeri, Aurelio J Dregni, Mei Hong
Journal: J Phys Chem B
PubMed ID: 37606918
Doi: 10.1021/acs.jpcb.3c05295
Products & Services: Molecular Biology Reagents   
design of buttressed loops for sculpting protein functions
Authors: Hanlun Jiang, Kevin M Jude, Kejia Wu, Jorge Fallas, George Ueda, T J Brunette, Derrick Hicks, Harley Pyles, Aerin Yang, Lauren Carter, Mila Lamb, Xinting Li, Paul M Levine, Lance Stewart, K Christopher Garcia, David Baker
Journal: biorxiv
PubMed ID: 37662224
Doi: 10.1101/2023.08.22.554384
Products & Services: Catalog Peptides   
Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer's Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice
Authors: Yang Zhu, Hao Huang, Zhi Chen, Yong Tao, Ling-Yi Liao, Shi-Hao Gao, Yan-Jiang Wang, Chang-Yue Gao
Journal: Neurosci Bull
PubMed ID: 37578635
Doi: 10.1007/s12264-023-01098-7
Hybrid structural modeling of alloantibody binding to human leukocyte antigen with rapid and reproducible cross-linking mass spectrometry
Authors: Zheng Ser, Yue Gu, Jiawei Yap, Yan Ting Lim, Shi Mei Wang, Maryam Hamidinia, Tanusya Murali Murali, Ragini Kumar, Nicholas Rj Gascoigne, Paul A MacAry, Radoslaw M Sobota
Journal: Cell Rep Methods
PubMed ID: 37751693
Doi: 10.1016/j.crmeth.2023.100569
Products & Services: Gene Synthesis   
Sequential Targeting Hybrid Nanovesicles Composed of Chimeric Antigen Receptor T-Cell-Derived Exosomes and Liposomes for Enhanced Cancer Immunochemotherapy
Authors: Tianchuan Zhu, Zhenxing Chen, Guanmin Jiang, Xi Huang
Journal: ACS Nano
PubMed ID: 37624742
Doi: 10.1021/acsnano.3c03456
A new compact adenine base editor generated through deletion of HNH and REC2 domain of SpCas9
Authors: Yuqiang Qian , Di Wang , Wenchao Niu , Ding Zhao , Jinze Li , Zhiquan Liu , Xun Gao , Yang Han , Liangxue Lai , Zhanjun Li
Journal: BMC Biol .
PubMed ID: 37434184
Doi: 10.1186/s12915-023-01644-9
Products & Services: Synthetic sgRNA and crRNA Service   
Glc7/PP1 dephosphorylates histone H3T11 to regulate autophagy and telomere silencing in response to nutrient availability
Authors: Xinyu Zhang, Qi Yu, Yinsheng Wu, Yuan Zhang, Yi He, Rongsha Wang, Xilan Yu,Shanshan Li
Journal: Cell Discovery
Doi: 10.1038/s41421-023-00551-1
Chemo-enzymatic cascades producing 2,5- furandicarboxylic acid precursors via D-gluconate “barbell oxidation” and dehydration
Authors: Jiao Chen, a,b Jiali Cai,c Feng Sha,d Wenjun Sun,a Xilei Lyu,e Yonghui Chang,f Fei Cao, Lili Zhao, Hongli Wu and Pingkai Ouyang
Journal: Green Chem.
Doi: 10.1039/d3gc01493b
Products & Services: Gene Synthesis   
Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells
Authors: Praveen Kumar Jadi, Alpana Dave, Rahaf Issa, Khatija Tabbasum, Katarzyna Okurowska, Apurwa Samarth, Lucy Urwin, Luke R Green, Lynda J Partridge, Sheila MacNeil, Prashant Garg, Peter N Monk, Sanhita Roy
Journal: Ocul Surf
PubMed ID: 37406881
Doi: 10.1016/j.jtos.2023.07.001
Products & Services: Molecular Biology Reagents   
A positively tuned voltage indicator for extended electrical recordings in the brain
Authors: S Wenceslao Evans, Dong-Qing Shi, Mariya Chavarha, Mark H Plitt, Jiannis Taxidis, Blake Madruga, Jiang Lan Fan, Fuu-Jiun Hwang, Siri C van Keulen, Carl-Mikael Suomivuori, Michelle M Pang, Sharon Su, Sungmoo Lee, Yukun A Hao, Guofeng Zhang, Dongyun Jiang, Lagnajeet Pradhan, Richard H Roth, Yu Liu, Conor C Dorian, Austin L Reese, Adrian Negrean, Attila Losonczy, Christopher D Makinson, Sui Wang, Thomas R Clandinin, Ron O Dror, Jun B Ding, Na Ji, Peyman Golshani, Lisa M Giocomo, Guo-Qiang Bi, Michael Z Lin
Journal: Nat Methods
PubMed ID: 37429962
Doi: 10.1038/s41592-023-01913-z
Products & Services: Molecular Biology Reagents   
Process Robustness in Lipid Nanoparticle Production: A Comparison of Microfluidic and Turbulent Jet Mixing
Authors: Matthew N O'Brien Laramy, Antonio P Costa, Yareli Maciel Cebrero, Johnson Joseph, Apoorva Sarode, Nanzhi Zang, Lee Joon Kim, Kate Hofmann, Shirley Wang, Alexandre Goyon, Stefan G Koenig, Michal Hammel, Greg L Hura
Journal: Mol Pharm
PubMed ID: 37462906
Doi: 10.1021/acs.molpharmaceut.3c00390
Decoding a cryptic mechanism of metronidazole resistance among globally disseminated fluoroquinolone-resistant Clostridioides difficile
Authors: Abiola O Olaitan, Chetna Dureja, Madison A Youngblom, Madeline A Topf, Wan-Jou Shen, Anne J Gonzales-Luna, Aditi Deshpande, Kirk E Hevener, Jane Freeman, Mark H Wilcox, Kelli L Palmer, Kevin W Garey, Caitlin S Pepperell, Julian G Hurdle
Journal: Nat Commun
PubMed ID: 37438331
Doi: 10.1038/s41467-023-39429-x
Products & Services: Molecular Biology Reagents   
Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection
Authors: Gregory M Martin, Jonathan L Torres, Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Grace Gibson, Re'em Moskovitz, Nathan Beutler, Diana D Jung, Jeffrey Copps, Wen-Hsin Lee, Gonzalo Gonzalez-Paez, Daniel Emerling, Randall S MacGill, Emily Locke, C Richter King, Fidel Zavala, Ian A Wilson, Andrew B Ward
Journal: Nat Commun
PubMed ID: 37507365
Doi: 10.1038/s41467-023-40151-x
Products & Services: Molecular Biology Reagents   
Effective virus-specific T-cell therapy for high-risk SARS-CoV-2 infections in hematopoietic stem cell transplant recipients: initial case studies and literature review
Authors: László Gopcsa, Marienn Réti, Hajnalka Andrikovics, Ilona Bobek, Gabriella Bekő, Judit Bogyó, Andrea Ceglédi, Katalin Dobos, Laura Giba-Kiss, István Jankovics, Orsolya Kis, Botond Lakatos, Dóra Mathiász, Nóra Meggyesi, Gottfried Miskolczi, Noémi Németh, Melinda Paksi, Alexandra Riczu, János Sinkó, Bálint Szabó, Anikó Szilvási, János Szlávik, Szabolcs Tasnády, Péter Reményi, István Vályi-Nagy
Journal: Geroscience
PubMed ID: 37414968
Doi: 10.1007/s11357-023-00858-7
Products & Services: Serology SARS-Cov-2 detection kits   
Development of chimeric protein as a multivalent vaccine for human Kinetoplastid infections: Chagas disease and leishmaniasis
Authors: Marianna de Carvalho Clímaco, Luiza Almeida de Figueiredo, Rayane Cristina Lucas, Guilherme Rafael Gomide Pinheiro, Luísa Mourão Dias Magalhães, Ana Laura Grossi de Oliveira, Raquel Martins Almeida, Fernando Sérgio Barbosa, Daniella Castanheira Bartholomeu, Lilian Lacerda Bueno, Tiago Antonio Mendes, Bin Zhan, Kathryn Marie Jones, Peter Hotez, Maria Elena Bottazzi, Fabrício Marcus Silva Oliveira, Ricardo Toshio Fujiwara
Journal: Vaccine
PubMed ID: 37479612
Doi: 10.1016/j.vaccine.2023.07.020
Products & Services: Gene Synthesis   
Integrated analysis and validation of TRIM23/p53 signaling pathway in hepatic stellate cells ferroptosis and liver fibrosis
Authors: Jie Chen, Rui Zhang, Feng Li, Shengli Lin, Jian Wang
Journal: Dig Liver Dis
PubMed ID: 37495427
Doi: 10.1016/j.dld.2023.07.010
Products & Services: Molecular Biology Reagents   
Tetracycline-modifying enzyme SmTetX from Stenotrophomonas maltophilia
Authors: Martin Malý, Petr Kolenko, Jan Stránský, Leona Švecová, Jarmila Dušková, Tomáš Koval', Tereza Skálová, Mária Trundová, Kristýna Adámková, Jiří Černý, Paulína Božíková, Jan Dohnálek
Journal: Acta Crystallogr F Struct Biol Commun
PubMed ID: 37405486
Doi: 10.1107/S2053230X23005381
PSW1, an LRR receptor kinase, regulates pod size in peanut
Authors: Kunkun Zhao, Long Wang, Ding Qiu, Zenghui Cao, Kuopeng Wang, Zhan Li, Xiaoxuan Wang, Jinzhi Wang, Qian Ma, Di Cao, Yinyao Qi, Kai Zhao, Fangping Gong, Zhongfeng Li, Rui Ren, Xingli Ma, Xingguo Zhang, Feng Yu, Dongmei Yin
Journal: Plant Biotechnol J
PubMed ID: 37431286
Doi: 10.1111/pbi.14117
Aflatoxin B1 Exacerbates Genomic Instability and Apoptosis in the BTBR Autism Mouse Model via Dysregulating DNA Repair Pathway
Authors: Ali A Alshamrani, Mohammad Y Alwetaid, Mohammed A Al-Hamamah, Mohamed S M Attia, Sheikh F Ahmad, Majed A Algonaiah, Ahmed Nadeem, Mushtaq A Ansari, Saleh A Bakheet, Sabry M Attia
Journal: Toxics
PubMed ID: 37505601
Doi: 10.3390/toxics11070636
Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice
Authors: Liming Yu, Lin Xu, Haiyan Chu, Jun Peng, Anastasia Sacharidou, Hsi-Hsien Hsieh, Ada Weinstock, Sohaib Khan, Liqian Ma, José Gabriel Barcia Durán, Jeffrey McDonald, Erik R Nelson, Sunghee Park, Donald P McDonnell, Kathryn J Moore, Lily Jun-Shen Huang, Edward A Fisher, Chieko Mineo, Linzhang Huang, Philip W Shaul
Journal: Nat Commun
PubMed ID: 37491347
Doi: 10.1038/s41467-023-39586-z
gene knockdown induces insect cell lines death and level increases of intracellular calcium ions
Authors: Jiqiang Song, Yanping Yu, Zhichao Yan, Shan Xiao, Xianxin Zhao, Fang Wang, Qi Fang, Gongyin Ye
Journal: Front Physiol
PubMed ID: 37485065
Doi: 10.3389/fphys.2023.1217954

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