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Phage-associated Cas12p nucleases require binding to bacterial thioredoxin for activation and cleavage of target DNA

Authors: Zhipeng Wang, Yujue Wang, Hui Gao, Jiani Dai, Na Tang, Yannan Wang, Quanjiang Ji

Journal: Nature Microbiology

PubMed ID: 41492065

Doi: 10.1038/s41564-025-02224-z

Products & Services: Protein Electrophoresis and Western

Antibody-induced internalization and degradation of PLA2R amplifies CD4+ T cell activation

Authors: Yuning Liu, Yinyin Li, Hui Zhou, Jieli Yu, Pei Deng, Weiwei Xu, Bingqian Pan, Lei Zhang, Hong Zhou, Jing Zhang, Xiaohan Liu, Min Shi, Xianchi Dong, Bei Tong, Enguang Bi, Nannan Guo, Yu Hu

Journal: Theranostics

PubMed ID: 41328348

Doi: 10.7150/thno.123035

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Reversible phase dynamics of PsAF5 regulate mitophagy to balance redox levels in Phytophthora sojae

Authors: Jinzhu Chen, Wenhao Li, Qin Peng, Hongwei Zhu, Tan Dai, Jianqiang Miao, Xili Liu

Journal: SCIENCE ADVANCES

PubMed ID: 41533793

Doi: 10.1126/sciadv.adz2785

Products & Services: Protein and Antibody Isolation

Structural decoding of reversible covalent linkage of odorants in human olfactory receptor OR6A2

Authors: Tian Wang, Yiran Wu, Ling Wang, Shanshan Li, Fei Zhao, Lijie Wu, Yue Liu, Jingzi Qin, Qiwen Tan, Junlin Liu, Liting Zeng, Yilin Chen, Shenyuan Gao, Wenqing Shui, Suwen Zhao, Tian Hua, Zhi-Jie Liu

Journal: Cell

PubMed ID: 41570822

Doi: 10.1016/j.cell.2025.12.017

Products & Services: Protein Electrophoresis and Western

Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains

Authors: Tyler N. Starr; Allison J. Greaney; Cameron M. Stewart; Alexandra C. Walls; William W. Hannon; David Veesler; Jesse D. Bloom; Marco Vignuzzi; Chris Ka Pun Mok; Marco Vignuzzi; Chris Ka Pun Mok; Marco Vignuzzi; Chris Ka Pun Mok

Journal: PLOS Pathogens

PubMed ID: 36399443

Doi: 10.1371/journal.ppat.1010951

Molecular mechanism of ziresovir targeting the fusion glycoprotein of respiratory syncytial virus

Authors: Mengrong Yan; Jingjing Zou; Zhao Gao; Haiqing Yuan; Jim Zhen Wu; Gang Zou; Fengjiang Liu; Wei Peng

Journal: PLOS Pathogens

PubMed ID: 41576151

Doi: 10.1371/journal.ppat.1013864

Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor

Authors: Gang Ye; Fan Bu; Hailey Turner-Hubbard; Morgan Herbst; Lanying Du; Ge Yang; Bin Liu; Fang Li

Journal: Nature

PubMed ID: 41813895

Doi: 10.1038/s41586-026-10240-0

Products & Services: Gene Synthesis

Chemical inhibition of a bacterial immune system

Authors: Zhiyu Zang; Olivia K. Duncan; Dziugas Sabonis; Iana Fedorova; Yun Shi; Gause Miraj; Shuai Le; Jun Deng; Yuhao Zhu; Yanyao Cai; Chengqian Zhang; Garima Arya; Shelley A. H. Dixon; Steven P. Angus; Breck A. Duerkop; Haihua Liang; Robert H. Pepin; Thomas Ve; Joseph Bondy-Denomy; Giedre Tamulaitiene; Joseph P. Gerdt

Journal: Cell Host & Microbe

PubMed ID: 41619738

Doi: 10.1016/j.chom.2026.01.003

Enhanced Production of HCV E1E2 Subunit Vaccine Candidates via Protein-Protein Interaction Identification in Glycoengineered CHO cells

Authors: Mina Ying Min Wu; Frances Rocamora; Caressa M. Robinson; Seunghyeon Shin; Eric A. Toth; Thomas R. Fuerst; Svetlana Maurya; Nathan E. Lewis

Journal: biorxiv

PubMed ID: 40475571

Doi: 10.1101/2025.05.20.655202

Enhanced Production of HCV E1E2 Subunit Vaccine Candidates via Protein-Protein Interaction Identification in Glycoengineered CHO cells

Authors: Mina Ying Min Wu; Frances Rocamora; Caressa M. Robinson; Seunghyeon Shin; Eric A. Toth; Thomas R. Fuerst; Svetlana Maurya; Nathan E. Lewis

Journal: biorxiv

PubMed ID: 40475571

Doi: 10.1101/2025.05.20.655202