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页码: 24/5233 每页显示数量

Wild-type KRAS activation drives evasion of interferon-mediated immunity and resistance to immunotherapy in hepatocellular carcinoma

Authors: Martina Mang Leng Lei, Carmen Oi Ning Leung, Rainbow Wing Hei Leung, Xue Qian Wu, Katherine Po Sin Chung, Catherine Yu Jia Gu, Mandy Sze Man Chan, Wing Ki Chau, Quan Hua Mu, Kai Yu Ng, Man Tong, Jing Ping Yun, Jia Ming Nickolas Teo, Guang Sheng Ling, Patrick Pak Chun Wong, Stephen Lam Chan, Zhe Wen Xiong, Alfred Sze Lok Cheng, Jin Ding, Stephanie Ma, Terence Kin Wah Lee

Journal: Nature Communications

PubMed ID: 41219194

Doi: 10.1038/s41467-025-64860-7.

Products & Services: Mutagenesis Services

Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins

Authors: Wenjian Han, Bo Yuan, Xiaojuan Fan, Weike Li, Yiting Yuan, Yuefang Zhang, Shu Wang, Shifang Shan, Markus Hafner, Zefeng Wang, Zilong Qiu

Journal: Nature Communications

PubMed ID: 41188225

Doi: 10.1038/s41467-025-64748-6.

Products & Services: Gene Synthesis

Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma

Authors: Edward Z Song, Andrea Timpanaro, Michael Meechan, Leonel Elena-Sanchez, Lucy Z Li, Sophie Jamet, Davina S Lau, Lily I Winter, Matthew D Dun, Jessica B Foster, Myron K Evans, Siobhan S Pattwell, Vandana Kalia, Surojit Sarkar, Michael C Jensen, Matthew C Biery, Nicholas A Vitanza

Journal: Nature Communications

PubMed ID: 41219209

Doi: 10.1038/s41467-025-64861-6.

Products & Services: Protein and Antibody Isolation

Control of Mycobacterium tuberculosis protein secretion by ESX-4 and the outer membrane EsxUT-EsxEF complex

Authors: Rashmi Ravindran Nair, Virginia Meikle, Swati Dubey, Mikhail Pavlenok, Anna D Tischler, Michael Niederweis

Journal: Nature Communications

PubMed ID: 41266320

Doi: 10.1038/s41467-025-65061-y.

Products & Services: Polyclonal Antibody Services

Structural snapshots capture nucleotide release at the μ-opioid receptor

Authors: Saif Khan, Aaliyah S Tyson, Mohsen Ranjbar, Zixin Zhang, Jaskaran Singh, Gye Won Han, Cornelius Gati

Journal: Nature

PubMed ID: 41193810

Doi: 10.1038/s41586-025-09677-6.

Products & Services: Catalog Peptides

Glycerol-3-phosphate activates ChREBP, FGF21 transcription and lipogenesis in citrin deficiency

Authors: Vinod Tiwari, Byungchang Jin, Olivia Sun, Edwin D J Lopez Gonzalez, Min-Hsuan Chen, Xiwei Wu, Hardik Shah, Andrew Zhang, Mark A Herman, Cassandra N Spracklen, Russell P Goodman, Charles Brenner

Journal: Nature metabolism

PubMed ID: 41238906

Doi: 10.1038/s42255-025-01399-3.

Comparative analysis of adenovirus, mRNA, and protein vaccines reveals context-dependent immunogenicity and efficacy

Authors: Bakare Awakoaiye, Shiyi Li, Sarah Sanchez, Tanushree Dangi, Nahid Irani, Laura Arroyo, Gabriel Arellano, Shadi Mohammadabadi, Malika Aid, Pablo Penaloza-MacMaster

Journal: JCI Insight

PubMed ID: 41212056

Doi: 10.1172/jci.insight.198069

Products & Services: Custom mRNA synthesis

Potential of ferulic acid as a food-derived cardioprotective agent targeting mitochondrial dysfunction

Authors: Duanrui Cao, Lina Huang, Xiaowei Lu, Junhua Meng, Wenhong Li, Delin Duan, Qianqian Wang, Cuiping Liu, Zidong Qiu, Ni Zhang

Journal: Food Bioscience

Doi: //doi.org/10.1016/j.fbio.2025.107704

Products & Services: Custom DNA/RNA Oligos

Enhanced antigen presentation by macrophages promotes human atherosclerosis progression: therapeutic implications

Authors: Yuhuai Xie, Que Wu, Yunhui Jia, Lianping Cheng, Yaru Tian, Xian Yang, Wei Wang, Wei Xu, Zhen Zhao, Yuanyuan Wei

Journal: European heart journal

PubMed ID: 41217874

Doi: 10.1093/eurheartj/ehaf878

Products & Services: Synthetic Guide RNA

Structural and functional characterization of TgGSK3, a druggable kinase in Toxoplasma gondii

Authors: Silvia Diaz-Martin, Christopher Swale, Valeria Bellini, Irina Dobrescu, Janine Wenker, Marie-Pierre Brenier-Pinchart, Laurence Braun, Alwéna Tollec, Charlotte Corrao, Yohann Couté, Caroline Mas, Fabrice Laurent, Matthew Bowler, Mohamed-Ali Hakimi, Alexandre Bougdour

Journal: Nature Communications

PubMed ID: 41193440

Doi: 10.1038/s41467-025-64701-7.

Products & Services: Gene Synthesis