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FUS nanoclusters are a distinct state within the dilute phase

Authors: Yingda Ge, Tapas Paul, Margarita Gordiychuk, Nilimesh Das, Yaojun Zhang, Sua Myong

Journal: Nature Communications

PubMed ID: 41224766

Doi: 10.1038/s41467-025-64909-7.

TNC-targeted CAR-macrophage therapy alleviates liver fibrosis in mice

Authors: Kai-Zhao Chen, Zi-Yang Lin, Long-Jun Chen, You-Xi Zhou, Wei Zhang, Hao-Yang Wan, Yong-Kun Huo, Qi Fu, Zi-Qing Gao, Hong-Wei Cheng, Xiao-Dong Ma, Shuai-Shuai Zhang

Journal: Military Medical Research

PubMed ID: 41214839

Doi: 10.1186/s40779-025-00667-3

Products & Services: Protein and Antibody Isolation

Double-stranded DNA deaminase DddAE1347A can increase the efficiency and targeting range of cytidine base editors

Authors: Yuqiang Qian, Fengjiao Hui, Wenchao Niu, Di Wang, Yang Hao, Qingying Meng, Siyu Ren, Deqiang Kong, Heng Gong, Jiayu Wu, Kexin Chen, Muna Alariqi, Junping Gao, Zhanjun Li, Shuangxia Jin

Journal: Genome Biology

PubMed ID: 41250247

Doi: doi.org/10.1186/s13059-025-03849-3

Products & Services: Gene Fragments

RBM39 Contributes to MGMT Maintenance in Response to Temozolomide-Induced DNA Damage

Authors: Vahid Khalaj, Jack T Adams, Solmaz AghaAmiri, Servando Hernandez Vargas, Tyler M Bateman, Sukhen C Ghosh, Majid Momeny, Ali Azhdarinia

Journal: Cancers

PubMed ID: 41300971

Doi: 10.3390/cancers17223604

Products & Services: Protein Electrophoresis and Western

Amplification-free cancer diagnosis based on inhibition of Cas12a activity by site-specific 5mC-modified cfDNA

Authors: Feng Yang, Can Xu, Chunhong Li, Xinni Xiang, Yi Zhao, Cong Hu, Huan Rong, Yu He, Jingyu Li, Yu Wang, Chao Tang, Xiaoyu Liu, Renyan Li, Fei Deng, Tingxiu Xiang

Journal: Nucleic Acids Research

PubMed ID: 41404798

Doi: doi.org/10.1093/nar/gkaf1383

Products & Services: Catalog Gene Editing

Nonexpansive biodegradable matrix promotes blood vessel organoid development for neurovascular repair and functional recovery in ischaemic stroke

Authors: Dongling Xiao, Yue Sun, Guanyuan Yang, Weixi Yan, Meilin Jiang, Zhongliang Qin, Zijun Wang, Yawei Gu, Jingting Zhou, Ju Tan, Gang Li, Yinghao Li, Chuhong Zhu

Journal: Nature biomedical engineering

PubMed ID: 41184604

Doi: 10.1038/s41551-025-01550-1

Products & Services: Peptide Library Services

Intravaginal delivery of mRNA-encoded antibodies with enhanced breadth and potency for SHIV/HIV protection

Authors: Jae Yeon Joo, Peng Xiao, Susan P John, Daryll Vanover, Hannah E Peck, Loren E Sasser, Deepanwita Bose, Younghun Jung, Jaehyeon Hwang, Chiara Zurla, Francois Villinger, Philip J Santangelo

Journal: Nature Communications

PubMed ID: 41290645

Doi: doi.org/10.1038/s41467-025-65456-x

Products & Services: Gene Synthesis Catalog Antibodies

Genome-Wide Identification of GW5-LIKE Family Revealed the Function of ClGL1 Involved in Fruit and Seed Shape by Mediating Brassinosteroid Signaling in Watermelon

Authors: Peng Tian, Lei Zhang, Jingjing Zhang, Bowen Liu, Wei Liu, Bing Li, Xiurui Gao, Jie Zhang, Yanrong Wu, Yong Xu

Journal: Horticulturae

Doi: 10.3390/horticulturae11111326

Products & Services: Custom DNA/RNA Oligos

Wild-type KRAS activation drives evasion of interferon-mediated immunity and resistance to immunotherapy in hepatocellular carcinoma

Authors: Martina Mang Leng Lei, Carmen Oi Ning Leung, Rainbow Wing Hei Leung, Xue Qian Wu, Katherine Po Sin Chung, Catherine Yu Jia Gu, Mandy Sze Man Chan, Wing Ki Chau, Quan Hua Mu, Kai Yu Ng, Man Tong, Jing Ping Yun, Jia Ming Nickolas Teo, Guang Sheng Ling, Patrick Pak Chun Wong, Stephen Lam Chan, Zhe Wen Xiong, Alfred Sze Lok Cheng, Jin Ding, Stephanie Ma, Terence Kin Wah Lee

Journal: Nature Communications

PubMed ID: 41219194

Doi: 10.1038/s41467-025-64860-7.

Products & Services: Mutagenesis Services

High expression of interleukin-18 receptor alpha correlates with severe respiratory viral disease and defines T cells with reduced cytotoxic signatures

Authors: Aira F Cabug, Jeremy Chase Crawford, Hayley A McQuilten, Isabelle J H Foo, Lilith F Allen, Deborah Gebregzabher, Robert C Mettelman, Tanya Novak, Janet Chou, Louise C Rowntree, Ruth R Hagen, Abby J Thomson, Genevieve E Martin, Brad Gilbertson, Michael Nt Souter, Fiona James, Emma Goodall, Simone Rizzetto, Tim Flerlage, Xiaoxiao Jia, Lee-Ann Van de Velde, So Young Chang, Fabio Luciani, Ryan S Thwaites, Jason A Trubiano, Tom C Kotsimbos, Allen C Cheng, Adrienne G Randolph, Paul G Thomas, Jianqing Xu, Zhongfang Wang, Thi H O Nguyen, Brendon Y Chua, Lukasz Kedzierski, Katherine Kedzierska

Journal: Nature Communications

PubMed ID: 41285788

Doi: 10.1038/s41467-025-65262-5.

Products & Services: Peptide Synthesis