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Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein

Authors: Qi Yang, Bao Xue, Fengjiang Liu, Yongzhi Lu, Jielin Tang, Mengrong Yan, Qiong Wu, Ruyi Chen, Anqi Zhou, Lijie Liu, Junjun Liu, Changbin Qu, Qingxin Wu, Muqing Fu, Jiayi Zhong, Jianwei Dong, Sijie Chen, Fan Wang, Yuan Zhou, Jie Zheng, Wei Peng, Jinsai Shang, Xinwen Chen

Journal: Signal Transduct Target Ther

PubMed ID: 38853183

Doi: 10.1038/s41392-024-01858-5

Products & Services: Catalog Peptides

Library-Assisted Evolution in Eukaryotic Cells Yield Adenine Base Editors with Enhanced Editing Specificity

Authors: Shenlin Hsiao, Shuanghong Chen, Yanhong Jiang, Qiudao Wang, Yang Yang, Yongrong Lai, Tao Zhong, Jiaoyang Liao, Yuxuan Wu

Journal: Adv Sci (Weinh)

PubMed ID: 38874509

Doi: 10.1002/advs.202309004

Products & Services: Molecular Biology Reagents

Microglia undergo sex-dimorphic transcriptional and metabolic rewiring during aging

Authors: Seokjo Kang, Emily Y Ko, Amelia E Andrews, Juliana E Shin, Karina J Nance, Pijus K Barman, Peter S Heeger, Willard M Freeman, Bérénice A Benayoun, Helen S Goodridge

Journal: J Neuroinflammation

PubMed ID: 38840206

Doi: 10.1186/s12974-024-03130-7

Products & Services: Protein Electrophoresis and Western

Discovery of RXFP2 genetic association in resistant hypertensive men and RXFP2 antagonists for the treatment of resistant hypertension

Authors: Shan-Shan Zhang, Lance Larrabee, Andrew H Chang, Sapna Desai, Lisa Sloan, Xin Wang, Yixuan Wu, Nazia Parvez, Karen Amaratunga, Allison C Hartman, Abby Whitnall, Joseph Mason, Nicholas P Barton, Audrey Y Chu, Jonathan M Davitte, Adam J Csakai, Caitlin Vestal Tibbetts, Audrey E Tolbert, Heather O'Keefe, Jessie Polanco, Joseph Foley, Casey Kmett, Jonathan Kehler, Gabriela Kozejova, Feng Wang, Andrew P Mayer, Patrick Koenig, Davide Foletti, Steven J Pitts, Christine G Schnackenberg

Journal: Sci Rep

PubMed ID: 38851835

Doi: 10.1038/s41598-024-62804-7

Products & Services: Molecular Biology Reagents

A phage nucleus-associated protein from the jumbophage Churi inhibits bacterial growth through protein translation interference

Authors: Wichanan Wannasrichan, Sucheewin Krobthong, Chase J Morgan, Emily G Armbruster, Milan Gerovac, Yodying Yingchutrakul, Patompon Wongtrakoongate, Jörg Vogel, Chanat Aonbangkhen, Poochit Nonejuie, Joe Pogliano, Vorrapon Chaikeeratisak

Journal: biorxiv

PubMed ID: 38915640

Doi: 10.1101/2024.06.15.599175

Products & Services: Molecular Biology Reagents

PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics

Authors: Sundaram Acharya, Asgar Hussain Ansari, Prosad Kumar Das, Seiichi Hirano, Meghali Aich, Riya Rauthan, Sudipta Mahato, Savitri Maddileti, Sajal Sarkar, Manoj Kumar, Rhythm Phutela, Sneha Gulati, Abdul Rahman, Arushi Goel, C Afzal, Deepanjan Paul, Trupti Agrawal, Vinay Kumar Pulimamidi, Subhadra Jalali, Hiroshi Nishimasu, Indumathi Mariappan, Osamu Nureki, Souvik Maiti, Debojyoti Chakraborty

Journal: Nat Commun

PubMed ID: 38942756

Doi: 10.1038/s41467-024-49233-w

Products & Services: Gene Synthesis

Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity

Authors: Siddhi Omkar, Courtney Shrader, Joel R Hoskins, Jake T Kline, Megan M Mitchem, Luca Fornelli, Sue Wickner, Andrew W Truman

Journal: biorxiv

PubMed ID: 38915721

Doi: 10.1101/2024.06.13.598777

Products & Services: Molecular Biology Reagents

miR-520e and its promoter region DNA methylation as potential biomarkers in atherosclerosis

Authors: Mimi Mu, Gao Liu, Xiaoyu Ding, Lijun Xue, Dandan Li, Yunhua Zhu, Nan Zhang, Jia Wu, Junjun Wang

Journal: Biochem Cell Biol

PubMed ID: 38917487

Doi: 10.1139/bcb-2023-0326

Products & Services: Molecular Biology Reagents

Experimental inoculation of pigs with monkeypox virus results in productive infection and transmission to sentinels

Authors: Emily Mantlo, Jessie D Trujillo, Natasha N Gaudreault, Igor Morozov, Charles E Lewis, Franco Matias-Ferreyra, Chester McDowell, Dashzeveg Bold, Taeyong Kwon, Konner Cool, Velmurugan Balaraman, Daniel Madden, Bianca Artiaga, Jayme Souza-Neto, Jeffrey B Doty, Mariano Carossino, Udeni Balasuriya, William C Wilson, Nikolaus Osterrieder, Lisa Hensley, Juergen A Richt

Journal: Emerg Microbes Infect

PubMed ID: 38712637

Doi: 10.1080/22221751.2024.2352434

Products & Services: PCR Cloning and Subcloning

Effect of TIMPs and Their Minimally Engineered Variants in Blocking Invasion and Migration of Brain Cancer Cells

Authors: Elham Taheri, Maryam Raeeszadeh-Sarmazdeh

Journal: biorxiv

PubMed ID: 38895489

Doi: 10.1101/2024.06.05.597644

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