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Dual functional POGases from bacteria encompassing broader O-glycanase and adhesin activities

Authors: Linjiao Zhou, Uriel Ortega-Rodriguez, Matthew J Flores, Yasuyuki Matsumoto, John Q Bettinger, Wells W Wu, Yaqin Zhang, Su-Ryun Kim, Thomas G Biel, Jordan D Pritts, Rong-Fong Shen, V Ashutosh Rao, Tongzhong Ju.

Journal: Nature Communications

PubMed ID: 40000644

Doi: 10.1038/s41467-025-57143-8

Products & Services: Codon Optimization

A ribosome-interacting jumbophage protein associates with the phage nucleus to facilitate efficient propagation

Authors: Wichanan Wannasrichan; Sucheewin Krobthong; Chase J. Morgan; Emily G. Armbruster; Milan Gerovac; Yodying Yingchutrakul; Patompon Wongtrakoongate; J rg Vogel; Chanat Aonbangkhen; Poochit Nonejuie; Joe Pogliano; Vorrapon Chaikeeratisak

Journal: PLOS Pathogens

PubMed ID: 39992933

Doi: 10.1371/journal.ppat.1012936

Structural Plasticity of RRE Stem-Loop II Modulates Nuclear Export of HIV-1 RNA

Authors: Manju Ojha; Lucia Hudson; Amanda Photenhauer; Trinity Zang; Lauren Lerew; len Ekesan; Jason Daniels; Megan Nguyen; Hardik Paudyal; Darrin M. York; Melanie D. Ohi; Jan Marchant; Paul D. Bieniasz; Deepak Koirala

Journal: biorxiv

PubMed ID: 40060702

Doi: 10.1101/2025.02.20.639096

Molecular mechanisms of drug resistance and compensation in SARS-CoV-2 main protease: the interplay between E166 and L50

Authors: Sarah N. Zvornicanin; Ala M. Shaqra; Julia Flynn; Heidi Carias Martinez; Weiping Jia; Stephanie Moquin; Dustin Dovala; Daniel N. Bolon; Nese Kurt Yilmaz; Celia A. Schiffer

Journal: MBio

PubMed ID: 40183562

Doi: 10.1128/mbio.04068-24

Products & Services: Peptide Synthesis

Squeeze pumping of lipids and insecticides by ABCH transporter

Authors: Jinli Chen, Yanwei Duan, Yuanyuan Zhou, Qing Yang

Journal: Cell

PubMed ID: 39721587

Doi: 10.1016/j.cell.2024.11.033

Products & Services: Catalog Antibodies

Expression, purification and characterization of a novel triple fusion protein developed for the immunotherapy of survivin positive cancers

Authors: Ambreen Rashid, Mohammad Azad, Anuja Krishnan, Jagdish C Gupta, G P Talwar

Journal: Protein Expression and Purification

PubMed ID: 39396748

Doi: 10.1016/j.pep.2024.106614

Products & Services: Gene Synthesis

The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma

Authors: Shahid Banday, Alok K Mishra, Romana Rashid, Tianyi Ye, Amjad Ali, Junhui Li, Jason T Yustein, Michelle A Kelliher, Lihua Julie Zhu, Sara K Deibler, Sunil K Malonia, Michael R Green

Journal: Nature Communications

PubMed ID: 39894896

Doi: 10.1038/s41467-025-56632-0

Products & Services: Plasmid DNA Preparation

Structural basis of SIRT7 nucleosome engagement and substrate specificity

Authors: Carlos Moreno-Yruela, Babatunde E Ekundayo, Polina N Foteva, Dongchun Ni, Esther Calvino-Sanles, Henning Stahlberg, Beat Fierz

Journal: Nature Communications

PubMed ID: 39900593

Doi: 10.1038/s41467-025-56529-y

Products & Services: Protein Electrophoresis and Western

Synthetic lethality of mRNA quality control complexes in cancer

Authors: Vivian Prindle, Adam E Richardson, Kimberly R Sher, Sarah Kongpachith, Kaitlin Kentala, Sakina Petiwala, Dong Cheng, Deborah Widomski, Phuong Le, Maricel Torrent, Anlu Chen, Stephen Walker, Marianne B Palczewski, Diya Mitra, Vlasios Manaves, Xu Shi, Charles Lu, Stephanie Sandoval, Zoltan Dezso, F Gregory Buchanan, Daniel Verduzco, Brian Bierie, Jonathan A Meulbroek, William N Pappano, Joshua P Plotnik

Journal: Nature

PubMed ID: 39910291

Doi: 10.1038/s41586-024-08398-6

Products & Services: Custom Vector Construction

Antibody prophylaxis may mask subclinical SIV infections in macaques

Authors: Christopher A Gonelli, Hannah A D King, SungYoul Ko, Christine M Fennessey, Nami Iwamoto, Rosemarie D Mason, Ashley Heimann, Dillon R Flebbe, John-Paul Todd, Kathryn E Foulds, Brandon F Keele, Jeffrey D Lifson, Richard A Koup, Mario Roederer.

Journal: Nature

PubMed ID: 39910294

Doi: 10.1038/s41586-024-08500-y

Products & Services: Gene Synthesis