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Network of hotspot interactions cluster tau amyloid folds

Authors: Vishruth Mullapudi, Jaime Vaquer-Alicea, Vaibhav Bommareddy, Anthony R Vega, Bryan D Ryder, Charles L White, Marc I Diamond, Lukasz A Joachimiak

Journal: Nat Commun

PubMed ID: 36797278

Doi: 10.1038/s41467-023-36572-3

Products & Services: Peptide Synthesis

Engineered biocontainable RNA virus vectors for non-transgenic genome editing across crop species and genotypes

Authors: Qian Liu, Chenglu Zhao, Kai Sun, Yinlu Deng, Zhenghe Li

Journal: Mol Plant

PubMed ID: 36751129

Doi: 10.1016/j.molp.2023.02.003

Products & Services: Peptide Synthesis

Efficient hydroxylation of flavonoids by using whole-cell P450 sca-2 biocatalyst in

Authors: Baodong Hu, Xinrui Zhao, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du

Journal: Front Bioeng Biotechnol

PubMed ID: 36873357

Doi: 10.3389/fbioe.2023.1138376

Products & Services: Gene Synthesis

Fused human paraoxonase 1 as a prophylactic agent against organophosphate poisoning

Authors: Prakashkumar Dobariya, Pratik Adhya, Bhupesh Vaidya, Prakash Y Khandave, Shyam Sunder Sharma, Abhay H Pande

Journal: Enzyme Microb Technol

PubMed ID: 36764031

Doi: 10.1016/j.enzmictec.2023.110209

Products & Services: Molecular Biology Reagents

Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions

Authors: Arun Kumar Somavarapu, Giulia Kleijwegt, Madhu Nagaraj, Parvez Alam, Janni Nielsen, Daniel E Otzen

Journal: Chem Sci

PubMed ID: 36937574

Doi: 10.1039/d2sc05534a

Products & Services: Recombinant Proteins

A rapid nucleic acid detection platform based on phosphorothioate-DNA and sulfur binding domain

Authors: Yuting Shuai, Yi Ju, Yuanhang Li, Dini Ma, Lan Jiang, Jingyu Zhang, Gao-Yi Tan, Xueting Liu, Shenlin Wang, Lixin Zhang, Guang Liu

Journal: Synth Syst Biotechnol

PubMed ID: 36875498

Doi: 10.1016/j.synbio.2023.02.002

Products & Services: Proteins, Expression, Isolation and Analysis

Two pan-SARS-CoV-2 nanobodies and their multivalent derivatives effectively prevent Omicron infections in mice

Authors: Honghui Liu, Lili Wu, Bo Liu, Ke Xu, Wenwen Lei, Jianguo Deng, Xiaoyu Rong, Pei Du, Lebing Wang, Dongbin Wang, Xiaolong Zhang, Chao Su, Yuhai Bi, Hua Chen, William J Liu, Jianxun Qi, Qingwei Cui, Shuhui Qi, Ruiwen Fan, Jingkun Jiang, Guizhen Wu, George F Gao, Qihui Wang

Journal: cell reports. medicine

PubMed ID: 36702124

Doi: 10.1016/j.xcrm

Products & Services: Gene Synthesis

Siglec-9 Restrains Antibody-Dependent Natural Killer Cell Cytotoxicity against SARS-CoV-2

Authors: Pratima Saini, Opeyemi S Adeniji, Devivasha Bordoloi, Jennifer Kinslow, Jeff Martinson, Danielle M Parent, Kai Ying Hong, Jane Koshy, Abhijeet J Kulkarni, Netanel F Zilberstein, Robert A Balk, James N Moy, Leila B Giron, Russell P Tracy, Ali Keshavarzian, Kar Muthumani, Alan Landay, David B Weiner, Mohamed Abdel-Mohsen

Journal: MBio

PubMed ID: 36728420

Doi: 10.1128/mbio.03393-22

Products & Services: Proteins, Expression, Isolation and Analysis

Cathepsin H and cathepsin B of Cynoglossus semilaevis are involved in anti-bacterial immunity against Edwardsiella tarda

Authors: Yilong Wang, Hang Xu, Boguang Sun

Journal: Fish Shellfish Immunol

PubMed ID: 36754156

Doi: 10.1016/j.fsi.2023.108594

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular basis of RADAR anti-phage supramolecular assemblies

Authors: Yina Gao, Xiu Luo, Peipei Li, Zhaolong Li, Feng Ye, Songqing Liu, Pu Gao