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Proteasomes accumulate in the plant apoplast where they participate in microbe-associated molecular pattern (MAMP)-triggered pathogen defense

Authors: Hana Zand Karimi, Kuo-En Chen, Marilee Karinshak, Xilin Gu, Jason K Sello, Richard D Vierstra

Journal: Nature Communications

PubMed ID: 39952938

Doi: 10.1038/s41467-025-56594-3

Products & Services: Peptide Synthesis

Antibody prophylaxis may mask subclinical SIV infections in macaques

Authors: Christopher A Gonelli, Hannah A D King, SungYoul Ko, Christine M Fennessey, Nami Iwamoto, Rosemarie D Mason, Ashley Heimann, Dillon R Flebbe, John-Paul Todd, Kathryn E Foulds, Brandon F Keele, Jeffrey D Lifson, Richard A Koup, Mario Roederer.

Journal: Nature

PubMed ID: 39910294

Doi: 10.1038/s41586-024-08500-y

Products & Services: Gene Synthesis

Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I

Authors: Bryan Neumann, Stephen McCarthy, Shane Gonen

Journal: Nature Communications

PubMed ID: 39920100

Doi: 10.1038/s41467-024-55764-z

Products & Services: Codon Optimization

GMRSP encoded by lncRNA H19 regulates metabolic reprogramming and alleviates aortic dissection

Authors: Jizhong Wang, Jitao Liu, Fan Yang, Yinghao Sun, Jiaohua Chen, Jie Liu, Tucheng Sun, Ruixin Fan, Fang Pei, Songyuan Luo, Jie Li, Jianfang Luo

Journal: Nature Communications

PubMed ID: 39966416

Doi: 10.1038/s41467-025-57011-5

The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma

Authors: Shahid Banday, Alok K Mishra, Romana Rashid, Tianyi Ye, Amjad Ali, Junhui Li, Jason T Yustein, Michelle A Kelliher, Lihua Julie Zhu, Sara K Deibler, Sunil K Malonia, Michael R Green

Journal: Nature Communications

PubMed ID: 39894896

Doi: 10.1038/s41467-025-56632-0

Products & Services: Plasmid DNA Preparation

Synthetic lethality of mRNA quality control complexes in cancer

Authors: Vivian Prindle, Adam E Richardson, Kimberly R Sher, Sarah Kongpachith, Kaitlin Kentala, Sakina Petiwala, Dong Cheng, Deborah Widomski, Phuong Le, Maricel Torrent, Anlu Chen, Stephen Walker, Marianne B Palczewski, Diya Mitra, Vlasios Manaves, Xu Shi, Charles Lu, Stephanie Sandoval, Zoltan Dezso, F Gregory Buchanan, Daniel Verduzco, Brian Bierie, Jonathan A Meulbroek, William N Pappano, Joshua P Plotnik

Journal: Nature

PubMed ID: 39910291

Doi: 10.1038/s41586-024-08398-6

Products & Services: Custom Vector Construction

Structural basis of SIRT7 nucleosome engagement and substrate specificity

Authors: Carlos Moreno-Yruela, Babatunde E Ekundayo, Polina N Foteva, Dongchun Ni, Esther Calvino-Sanles, Henning Stahlberg, Beat Fierz

Journal: Nature Communications

PubMed ID: 39900593

Doi: 10.1038/s41467-025-56529-y

Products & Services: Protein Electrophoresis and Western

Perturbing Organelle-Level K+/Ca2+ Homeostasis by Nanotherapeutics for Enhancing Ion-Mediated Cancer Immunotherapy

Authors: Jun-Long Liang , Qian-Xiao Huang , Qi-Wen Chen , Xiao-Kang Jin , Zi-Yi Han 1, Ping Ji , Si-Xue Cheng , Wei-Hai Chen , Xian-Zheng Zhang

Journal: Adv Mater

PubMed ID: 39955648

Doi: 10.1002/adma.202416574

Products & Services: Recombinant Proteins

Elastin-like polypeptide: A novel titanification biomacromolecule for green and ultrafast synthesis of biotitania nanoparticles via biomimetic mineralization

Authors: Lixi Cai, Jinlin Zheng, Lixing Liu, Guangya Zhang, Yuanqing Lin

Journal: Int J Biol Macromol

PubMed ID: 40015400

Doi: 10.1016/j.ijbiomac.2025.141449

Products & Services: Gene Synthesis

A Granzyme B‑Cleavable T Cell-Targeted Bispecific Cell Vesicle Connector for Reversing New-Onset Type 1 Diabetes

Authors: Yanfang Wang, Yanping Sun, Xiuwen Zhang, Shenqiang Wang, Xuehui Huang, Kairui Xu, Yun Liu, Yingqi Huang, Jianchang Xu, Xinwei Wei, Hao Cheng, Liqiang Pan, Jinqiang Wang, Zhen Gu

Journal: Journal of the American Chemical Society

PubMed ID: 39869523

Doi: 10.1021/jacs.4c13644

Products & Services: Gene Synthesis