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Distinct immunogenicity outcomes of DNA vaccines encoding malaria transmission-blocking vaccine target antigens Pfs230D1M and Pvs230D1

Authors: Yi Cao , Maisa da Silva Araujo , Cynthia G Lorang , Najara Akira Costa Dos Santos , Abhai Tripathi , Joseph Vinetz , Nirbhay Kumar

Journal: Vaccine

PubMed ID: 39787798

Doi: 10.1016/j.vaccine.2024.126696

Products & Services: Gene Synthesis Plasmid DNA Preparation

Establishment of an indirect ELISA method for detecting bovine coronavirus antibodies based on N protein

Authors: Qiang Liu , Xiaoxia Niu , Lingling Jiang , Gang Zhang , Pu Wang , Sinong Zhang , Weifeng Gao , Huichen Guo, Yujiong Wang and Yong Li

Journal: Frontiers in Veterinary Science

Doi: 10.3389/fvets.2025.1530870

Products & Services: Plasmid DNA Preparation

In vitro reconstitution of meiotic DNA double-strand-break formation

Authors: Xinzhe Tang , Zetao Hu , Jian Ding , Meixia Wu , Pin Guan , Yawei Song , Yue Yin , Wei Wu , Jinbiao Ma , Ying Huang , Ming-Han Tong

Journal: Nature

PubMed ID: 39972125

Doi: doi.org/10.1038/s41586-024-08551-1

Products & Services: Custom DNA/RNA Oligos

Identifying Exifone as a Dual-Target Agent Targeting Both SARS-CoV-2 3CL Protease and the ACE2/S-RBD Interaction Among Clinical Polyphenolic Compounds

Authors: Jiani Lu、Yan Tang、Hongtao Li、Xixiang Chen、Pengcheng Qin、Jianrong Xu、Weihua Li 和 Lili Chen

Journal: International Journal of Molecular Sciences

Doi: doi.org/10.3390/ijms26052243

Products & Services: Plasmid DNA Preparation

Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers

Authors: Kai Li, Xuan Yu, Yanteng Xu, Haixia Wang, Zheng Liu, Chong Wu, Xing Luo, Jiancheng Xu, Youqiang Fang, Enguo Ju, Shixian Lv, Hon Fai Chan, Yeh-Hsing Lao, Weiling He, Yu Tao, Mingqiang Li

Journal: Nature Communications

PubMed ID: 39952937

Doi: 10.1038/s41467-025-56407-7

Products & Services: Recombinant Proteins

The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma

Authors: Shahid Banday, Alok K Mishra, Romana Rashid, Tianyi Ye, Amjad Ali, Junhui Li, Jason T Yustein, Michelle A Kelliher, Lihua Julie Zhu, Sara K Deibler, Sunil K Malonia, Michael R Green

Journal: Nature Communications

PubMed ID: 39894896

Doi: 10.1038/s41467-025-56632-0

Products & Services: Plasmid DNA Preparation

Synthetic lethality of mRNA quality control complexes in cancer

Authors: Vivian Prindle, Adam E Richardson, Kimberly R Sher, Sarah Kongpachith, Kaitlin Kentala, Sakina Petiwala, Dong Cheng, Deborah Widomski, Phuong Le, Maricel Torrent, Anlu Chen, Stephen Walker, Marianne B Palczewski, Diya Mitra, Vlasios Manaves, Xu Shi, Charles Lu, Stephanie Sandoval, Zoltan Dezso, F Gregory Buchanan, Daniel Verduzco, Brian Bierie, Jonathan A Meulbroek, William N Pappano, Joshua P Plotnik

Journal: Nature

PubMed ID: 39910291

Doi: 10.1038/s41586-024-08398-6

Products & Services: Custom Vector Construction

Co-translational protein aggregation and ribosome stalling as a broad-spectrum antibacterial mechanism

Authors: Laleh Khodaparast, Ladan Khodaparast, Ramon Duran-Romaña, Guiqin Wu, Bert Houben, Wouter Duverger, Matthias De Vleeschouwer, Katerina Konstantoulea, Fleur Nysen, Thomas Schalck, Daniel J Curwen, Lisandra L Martin, Sebastien Carpentier, Bernard Scorneaux, Jan Michiels, Joost Schymkowitz, Frederic Rousseau

Journal: Nature Communications

PubMed ID: 39939597

Doi: 10.1038/s41467-025-56873-z

Products & Services: Peptide Synthesis

Structural basis of SIRT7 nucleosome engagement and substrate specificity

Authors: Carlos Moreno-Yruela, Babatunde E Ekundayo, Polina N Foteva, Dongchun Ni, Esther Calvino-Sanles, Henning Stahlberg, Beat Fierz

Journal: Nature Communications

PubMed ID: 39900593

Doi: 10.1038/s41467-025-56529-y

Products & Services: Protein Electrophoresis and Western

Proteasomes accumulate in the plant apoplast where they participate in microbe-associated molecular pattern (MAMP)-triggered pathogen defense

Authors: Hana Zand Karimi, Kuo-En Chen, Marilee Karinshak, Xilin Gu, Jason K Sello, Richard D Vierstra

Journal: Nature Communications

PubMed ID: 39952938

Doi: 10.1038/s41467-025-56594-3

Products & Services: Peptide Synthesis