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Production of the antidepressant orcinol glucoside in Yarrowia lipolytica with yields over 6,400-fold higher than plant extraction
Authors: Bihuan Chen , Xiaonan Liu , Yina Wang , Jie Bai , Xiangyu Liu , Guisheng Xiang , Wei Liu , Xiaoxi Zhu , Jian Cheng , Lina Lu , Guanghui Zhang , Ge Zhang, Zongjie Dai, Shuhui Zi , Shengchao Yang, Huifeng Jiang
Journal: PLoS Biol .
PubMed ID: 37279234
Doi: 10.1371/journal.pbio.3002131
Products & Services: Codon Optimization   
Discovery of deaminase functions by structure-based protein clustering
Authors: Jiaying Huang , Qiupeng Lin , Hongyuan Fei , Zixin He , Hu Xu , Yunjia Li , Kunli Qu , Peng Han , Qiang Gao , Boshu Li , Guanwen Liu , Lixiao Zhang , Jiacheng Hu , Rui Zhang , Erwei Zuo , Yonglun Luo , Yidong Ran , Jin-Long Qiu , Kevin Tianmeng Zhao , Caixia Gao
Journal: Cell .
PubMed ID: 37379837
Doi: 10.1016/j.cell.2023.05.041
Products & Services: Gene Synthesis   
Mutations F352A and Y528A in human HSP90α reduce fibronectin association and fibrillogenesis in cell-derived matrices
Authors: Abir Chakraborty, Ronald Tonui, Adrienne Lesley Edkins
Journal: Cell Stress Chaperones
PubMed ID: 37353709
Doi: 10.1007/s12192-023-01362-9
ATXN3 controls DNA replication and transcription by regulating chromatin structure
Authors: Esperanza Hernández-Carralero, Elisa Cabrera, Gara Rodríguez-Torres, Yeray Hernández-Reyes, Abhay N Singh, Cristina Santa-María, José Miguel Fernández-Justel, Roel C Janssens, Jurgen A Marteijn, Bernd O Evert, Niels Mailand, María Gómez, Kristijan Ramadan, Veronique A J Smits, Raimundo Freire
Journal: Nucleic Acids Res
PubMed ID: 36971114
Doi: 10.1093/nar/gkad212
Products & Services: Monoclonal Antibody Services   
Erythroid lineage chromatin accessibility maps facilitate identification and validation of NFIX as a fetal hemoglobin repressor
Authors: Mudit Chaand, Chris Fiore, Brian Johnston, Anthony D'Ippolito, Diane H Moon, John P Carulli, Jeffrey R Shearstone
Journal: Commun Biol
PubMed ID: 37316562
Doi: 10.1038/s42003-023-05025-4
Products & Services: PCR Cloning and Subcloning   
Electrochemical biosensor strategy combining DNA entropy-driven technology to activate CRISPR-Cas13a activity and triple-stranded nucleic acids to detect SARS-CoV-2 RdRp gene
Authors: Chenyi Zhuo, Zichun Song, Jiuying Cui, Yuanxun Gong, Qianli Tang, Kai Zhang, Xinlei Song, Xianjiu Liao
Journal: Mikrochim Acta
PubMed ID: 37351704
Doi: 10.1007/s00604-023-05848-2
Products & Services: Synthetic sgRNA and crRNA Service   
miR‑124 inhibits cardiomyocyte apoptosis in myocardial ischaemia‑reperfusion injury by activating mitochondrial calcium uniporter regulator 1
Authors: Linlin Guo, Chaoying Liu, Chunyan Jiang, Yanhan Dong, Lynn Htet Htet Aung, Han Ding, Yanyan Gao
Journal: Mol Med Rep
PubMed ID: 37326122
Doi: 10.3892/mmr.2023.13031
Products & Services: Molecular Biology Reagents   
Optimization of mammalian expression vector by cis-regulatory element combinations
Authors: Lu-Yu Zhou, Shuang Zhang, Li-Yun Li, Guo-Yu Yang, Lei Zeng
Journal: Mol Genet Genomics
PubMed ID: 37318628
Doi: 10.1007/s00438-023-02042-0
Products & Services: Gene Synthesis   
Enzyme assembly on nanoparticle scaffolds enhances cofactor recycling and improves coupled reaction kinetics
Authors: Joyce C Breger, Ellen R Goldman, Kimihiro Susumu, Eunkeu Oh, Christopher M Green, Shelby L Hooe, Meghna Thakur, Igor L Medintz, Gregory A Ellis
Journal: Nanoscale
PubMed ID: 37272342
Doi: 10.1039/d3nr00729d
In Vitro and In Vivo Efficacy of a Stroma-Targeted, Tumor Microenvironment Responsive Oncolytic Adenovirus in Different Preclinical Models of Cancer
Authors: Ana Alfano, Eduardo G A Cafferata, Mariela Gangemi, Alejandro Nicola Candia, Cristian M Malnero, Ismael Bermudez, Mauricio Vargas Lopez, Gregorio David Ríos, Cecilia Rotondaro, Nicasio Cuneo, David T Curiel, Osvaldo L Podhajcer, Maria Veronica Lopez
Journal: Int J Mol Sci
PubMed ID: 37373140
Doi: 10.3390/ijms24129992

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