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Immunological comparison of recombinant shrimp allergen Pen m 4, produced in Pichia pastoris and Escherichia coli

Authors: Juta Rainyte, Gintautas Zvirblis, Mindaugas Zaveckas, Indre Kucinskaite-Kodze, Laimis Silimavicius, Rasa Petraityte-Burneikiene

Journal: J Biotechnol

PubMed ID: 37164269

Doi: 10.1016/j.jbiotec.2023.05.002

Products & Services: Molecular Biology Reagents

Immune checkpoint B7-H3 is a therapeutic vulnerability in prostate cancer harboring PTEN and TP53 deficiencies

Authors: Wei Shi, Yin Wang, Yuehui Zhao, Justin Jimin Kim, Haoyan Li, Chenling Meng, Feiyu Chen, Jie Zhang, Duncan H Mak, Vivien Van, Javier Leo, Brad St Croix, Ana Aparicio, Di Zhao

Journal: Sci Transl Med

PubMed ID: 37163614

Doi: 10.1126/scitranslmed.adf6724

Products & Services: Molecular Biology Reagents

Encapsulated Allografts Preclude Host Sensitization and Promote Ovarian Endocrine Function in Ovariectomized Young Rhesus Monkeys and Sensitized Mice

Authors: James R Day, Colleen L Flanagan, Anu David, Dennis J Hartigan-O'Connor, Mayara Garcia de Mattos Barbosa, Michele L Martinez, Charles Lee, Jenna Barnes, Evan Farkash, Mary Zelinski, Alice Tarantal, Marilia Cascalho, Ariella Shikanov

Journal: Bioengineering (Basel)

PubMed ID: 37237620

Doi: 10.3390/bioengineering10050550

Products & Services: Molecular Biology Reagents

Phenotypic, Physiological, and Molecular Response of var under Different Light Quality Treatments Based on Leaf Color Changes

Authors: Yifan Zhang, Yang Liu, Lin Ling, Wenwen Huo, Yang Li, Lu Xu, Lili Xiang, Yujie Yang, Xingyao Xiong, Donglin Zhang, Xiaoying Yu, Yanlin Li

Journal: Plants (Basel)

PubMed ID: 37299148

Doi: 10.3390/plants12112169

Products & Services: Molecular Biology Reagents

DPY30 Promotes Proliferation and Cell Cycle Progression of Colorectal Cancer Cells via Mediating H3K4 Trimethylation

Authors: Wei-Chao Su, Xiao-Mei Mao, Si-Yang Li, Chun-Ying Luo, Rui Fan, Hai-Feng Jiang, Lin-Jun Zhang, Ya-Tao Wang, Guo-Qiang Su, Dong-Yan Shen

Journal: Int J Med Sci

PubMed ID: 37324189

Doi: 10.7150/ijms.80073

Products & Services: Protein Electrophoresis and Western

The global regulator SpoVG regulates Listeria monocytogenes biofilm formation

Authors: Changzheng Shi, Liping Zheng, Zhaoxin Lu, Xinyi Zhang, Xiaomei Bie

Journal: Microb Pathog

PubMed ID: 37148923

Doi: 10.1016/j.micpath.2023.106144

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High light triggers flavonoid and polysaccharide synthesis through DoHY5-dependent signaling in Dendrobium officinale

Authors: Dongxiao Li, Guangying Ye, Jie Li, Zhenqin Lai, Siyou Ruan, Qi Qi, Zaihua Wang, Sujuan Duan, Hong-Lei Jin, Hong-Bin Wang

Journal: Plant J

PubMed ID: 37177908

Doi: 10.1111/tpj.16284

Products & Services: Protein and Antibody Isolation

Optimal Expression, Function, and Immunogenicity of an HIV-1 Vaccine Derived from the Approved Ebola Vaccine, rVSV-ZEBOV

Authors: Hiva Azizi, Jason P Knapp, Yue Li, Alice Berger, Marc-Alexandre Lafrance, Jannie Pedersen, Marc-Antoine de la Vega, Trina Racine, Chil-Yong Kang, Jamie F S Mann, Jimmy D Dikeakos, Gary Kobinger, Eric J Arts

Journal: Vaccines (Basel)

PubMed ID: 37243081

Doi: 10.3390/vaccines11050977

Products & Services: Protein and Antibody Isolation

The Adjuvant Combination of dmLT and Monophosphoryl Lipid A Activates the Canonical, Nonpyroptotic NLRP3 Inflammasome in Dendritic Cells and Significantly Interacts to Expand Antigen-Specific CD4 T Cells

Authors: David L Bauer, Louay Bachnak, Vanessa M Limbert, Rebecca M Horowitz, Robin L Baudier, Shaina J D'Souza, Victoria E Immethun, Jonathan R Kurtz, Samuel B Grant, James B McLachlan

Journal: J Immunol

PubMed ID: 37023458

Doi: 10.4049/jimmunol.2200221

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African Swine Fever Virus HLJ/18 CD2v Suppresses Type I IFN Production and IFN-Stimulated Genes Expression through Negatively Regulating cGMP-AMP Synthase-STING and IFN Signaling Pathways

Authors: Li Huang, Weiye Chen, Hongyang Liu, Mengdi Xue, Siqi Dong, Xiaohong Liu, Chunying Feng, Shinuo Cao, Guangqiang Ye, Qiongqiong Zhou, Zhaoxia Zhang, Jun Zheng, Jiangnan Li, Dongming Zhao, Zilong Wang, Encheng Sun, Hefeng Chen, Shuai Zhang, Xue Wang, Xianfeng Zhang, Xijun He, Yuntao Guan, Zhigao Bu, Changjiang Weng

Journal: J Immunol

PubMed ID: 36971697

Doi: 10.4049/jimmunol.2200813

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Divergent expression of aristaless1 and aristaless2 during embryonic appendage and pupal wing development in butterflies

Authors: Erick X Bayala, Isabella Cisneros, Darli Massardo, Nicholas W VanKuren, Marcus R Kronforst

Journal: BMC Biol

PubMed ID: 37170114

Doi: 10.1186/s12915-023-01602-5

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Eight-Month Follow-up After the Third Dose of BNT162b2 Vaccine in Healthcare Workers: The Question of a Fourth Dose

Authors: Sung Hee Lim, Seong Hyeok Choi, Ji Youn Kim, Bora Kim, Han Jo Kim, Se Hyung Kim, Chan Kyu Kim, Seong Kyu Park, Jina Yun

Journal: J Korean Med Sci

PubMed ID: 37158775

Doi: 10.3346/jkms.2023.38.e139

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Adenoviral-vectored epigraph vaccine elicits robust, durable, and protective immunity against H3 influenza A virus in swine

Authors: Erika Petro-Turnquist, Matthew Pekarek, Nicholas Jeanjaquet, Cedric Wooledge, David Steffen, Hiep Vu, Eric A Weaver

Journal: Front Immunol

PubMed ID: 37256131

Doi: 10.3389/fimmu.2023.1143451

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Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex

Authors: Cassandra K Hayne, Kevin John U Butay, Zachary D Stewart, Juno M Krahn, Lalith Perera, Jason G Williams, Robert M Petrovitch, Leesa J Deterding, A Gregory Matera, Mario J Borgnia, Robin E Stanley

Journal: Nat Struct Mol Biol

PubMed ID: 37231153

Doi: 10.1038/s41594-023-00991-z

Products & Services: Gene Synthesis

An Aurora B-RPA signaling axis secures chromosome segregation fidelity

Authors: Poonam Roshan, Sahiti Kuppa, Jenna R Mattice, Vikas Kaushik, Rahul Chadda, Nilisha Pokhrel, Brunda R Tumala, Aparna Biswas, Brian Bothner, Edwin Antony, Sofia Origanti

Journal: Nat Commun

PubMed ID: 37230964

Doi: 10.1038/s41467-023-38711-2

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Chronic intermittent hypobaric hypoxia ameliorates osteoporosis after spinal cord injury through balancing osteoblast and osteoclast activities in rats

Authors: Li Zhang, Yingchao Yin, Jialiang Guo, Lin Jin, Zhiyong Hou

Journal: Front Endocrinol (Lausanne)

PubMed ID: 37229453

Doi: 10.3389/fendo.2023.1035186

Products & Services: PCR Cloning and Subcloning

Rapid Quantitation of Various Therapeutic Monoclonal Antibodies Using Membranes with Fc-Specific Ligands

Authors: Junyan Yang, Raluca Ostafe, Christopher J Welch, Brandy Verhalen, Ivan L Budyak, Merlin L Bruening

Journal: Anal Chem

PubMed ID: 37216615

Doi: 10.1021/acs.analchem.3c00531

Products & Services: Peptide Synthesis

Hemophore-like proteins produced by periodontopathogens are recognized by the host immune system and react differentially with IgG antibodies

Authors: Michał Śmiga, Klaudia Siemińska, Soraya C Trindade, Isaac S Gomes-Filho, Ellen K Nobre Dos Santos, Teresa Olczak

Journal: J Oral Microbiol

PubMed ID: 37213663

Doi: 10.1080/20002297.2023.2214455

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Synthesis and Evaluation of Clinically Translatable Targeted Microbubbles Using a Microfluidic Device for In Vivo Ultrasound Molecular Imaging

Authors: Rakesh Bam, Arutselvan Natarajan, Farbod Tabesh, Ramasamy Paulmurugan, Jeremy J Dahl

Journal: Int J Mol Sci

PubMed ID: 37240396

Doi: 10.3390/ijms24109048

Products & Services: Recombinant Proteins

Soluble monomeric human programmed cell death-ligand 1 inhibits the functions of activated T cells

Authors: Zhaoduan Liang, Wenfang Chen, Yunzhuo Guo, Yuefei Ren, Ye Tian, Wenxuan Cai, Yifeng Bao, Qi Liu, Peng Ding, Yi Li

Journal: Front Immunol

PubMed ID: 37266424

Doi: 10.3389/fimmu.2023.1133883

Products & Services: Stable Cell Lines

GNAQ-Regulated ZO-1 and ZO-2 Act as Tumor Suppressors by Modulating EMT Potential and Tumor-Repressive Microenvironment in Lung Cancer

Authors: Hyung Seok Kim, Su In Lee, Yu Rim Choi, Jiyun Kim, Jung Woo Eun, Kyoung Seob Song, Jee-Yeong Jeong

Journal: Int J Mol Sci

PubMed ID: 37240145

Doi: 10.3390/ijms24108801

Products & Services: Recombinant Proteins

Hijacking of Host Plasminogen by () via GAPDH: an Important Virulence Mechanism To Promote Adhesion and Extracellular Matrix Degradation

Authors: Jiying Wang, Shiyang Li, Junhong Chen, Lanxi Gan, Jia Wang, Qiyan Xiong, Zhixin Feng, Quan Li, Zhibang Deng, Xiaomin Yuan, Yanfei Yu

Journal: Microbiol Spectr

PubMed ID: 37199643

Doi: 10.1128/spectrum.00218-23

Products & Services: Molecular Biology Reagents

Identification of new conserved linear B-cell epitopes in the 3AB and 3C protein of Senecavirus A

Authors: Jian Li, Junfang Yan, Yanni Gao, Xing Liu, Haifeng Sun, Juan Bai, Ping Jiang

Journal: Vet Microbiol

PubMed ID: 37263042

Doi: 10.1016/j.vetmic.2023.109780

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MASP3 Deficiency in Mice Reduces but Does Not Abrogate Alternative Pathway Complement Activity Due to Intrinsic Profactor D Activity

Authors: Damodar Gullipalli, Takashi Miwa, Madhu Golla, Sayaka Sato, Sree Angampalli, Wen-Chao Song

Journal: J Immunol

PubMed ID: 36988282

Doi: 10.4049/jimmunol.2200932

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Development and characterization of nanobodies that specifically target the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3) and impact its interaction with a known binding partner, CNNM3

Authors: Caroline N Smith, Kyle Kihn, Zachary A Williamson, K Martin Chow, Louis B Hersh, Konstantin V Korotkov, Daniel Deredge, Jessica S Blackburn

Journal: PLoS ONE

PubMed ID: 37220097

Doi: 10.1371/journal.pone.0285964

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Bioluminescence resonance energy transfer biosensor for measuring activity of a protease secreted by Pseudomonas fluorescens growing in milk

Authors: H Dacres, F Weihs, J Wang, A Anderson, S C Trowell

Journal: Anal Chim Acta

PubMed ID: 37311608

Doi: 10.1016/j.aca.2023.341401

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Ligand and G-protein selectivity in the κ-opioid receptor

Authors: Jianming Han, Jingying Zhang, Antonina L Nazarova, Sarah M Bernhard, Brian E Krumm, Lei Zhao, Jordy Homing Lam, Vipin A Rangari, Susruta Majumdar, David E Nichols, Vsevolod Katritch, Peng Yuan, Jonathan F Fay, Tao Che

Journal: Nature

PubMed ID: 37138078

Doi: 10.1038/s41586-023-06030-7

Products & Services: Protein and Antibody Isolation

Diversity and Genetic Reassortment of Keystone Virus in Mosquito Populations in Florida

Authors: Maha A Elbadry, Caroline A Efstathion, Whitney A Qualls, Massimiliano S Tagliamonte, Md Mahbubul Alam, Md Siddiqur Rahman Khan, Sadie J Ryan, Rui-de Xue, Remi N Charrel, Lea Bangonan, Marco Salemi, Nazli Ayhan, John A Lednicky, J Glenn Morris

Journal: Am J Trop Med Hyg

PubMed ID: 37127267

Doi: 10.4269/ajtmh.22-0594

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Photobiomodulation therapy at 632 nm wavelength ameliorates intrauterine adhesion via activation of cAMP/PKA/CREB pathway

Authors: Hongjie Zheng, Caixia Wang, Shan Wu, Qing Pei, Min Yao

Journal: Photochem Photobiol

PubMed ID: 37212452

Doi: 10.1111/php.13813

Products & Services: Protein and Antibody Isolation

Site-specific gene knock-in and bacterial phytase gene expression in Cas9 RNP-mediated HDR

Authors: Hassan Zadabbas Shahabadi, Arash Akbarzadeh, Hamideh Ofoghi, Saeid Kadkhodaei

Journal: Front Plant Sci

PubMed ID: 37275253

Doi: 10.3389/fpls.2023.1150436

Products & Services: Protein and Antibody Isolation

Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma

Authors: Damon A Hofman, Jorge Ruiz-Orera, Ian Yannuzzi, Rakesh Murugesan, Adam Brown, Karl R Clauser, Alexandra L Condurat, Jip T van Dinter, Sem A G Engels, Amy Goodale, Jasper van der Lugt, Tanaz Abid, Li Wang, Kevin N Zhou, Jayne Vogelzang, Keith L Ligon, Timothy N Phoenix, Jennifer A Roth, David E Root, Norbert Hubner, Todd R Golub, Pratiti Bandopadhayay, Sebastiaan van Heesch, John R Prensner

Journal: biorxiv

PubMed ID: 37205492

Doi: 10.1101/2023.05.04.539399

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Ovarian juvenile granulosa cell tumors with Ollier's disease in children with IDH1 gene somatic mutation

Authors: Jin Zhang, Renwu Hua, Lishuang Ma, Chao Liu, Yanxia Zhang, Xuemin Lü, Tianren Wang, Naijun Wan

Journal: Front Endocrinol (Lausanne)

PubMed ID: 37324278

Doi: 10.3389/fendo.2023.1093273

Products & Services: Protein and Antibody Isolation

Characterisation of IL-23 receptor antagonists and disease relevant mutants using fluorescent probes

Authors: Charles S Lay, Albert Isidro-Llobet, Laura E Kilpatrick, Peter D Craggs, Stephen J Hill

Journal: Nat Commun

PubMed ID: 37208328

Doi: 10.1038/s41467-023-38541-2

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The secretory IgA (sIgA) response in human milk against the SARS-CoV-2 Spike is highly durable and neutralizing for at least 1 year of lactation post-infection

Authors: Xiaoqi Yang, Alisa Fox, Claire DeCarlo, Nicole Pineda, Rebecca L R Powell

Journal: medrxiv

PubMed ID: 37293109

Doi: 10.1101/2023.05.19.23290192

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Prognostic impact of kallikrein-related peptidase transcript levels in prostate cancer

Authors: Timo-Pekka K Lehto, Ruusu-Maaria Kovanen, Susanna Lintula, Adrian Malén, Carolin Stürenberg, Andrew Erickson, Olli-Pekka Pulkka, Ulf-Håkan Stenman, Eleftherios P Diamandis, Antti Rannikko, Tuomas Mirtti, Hannu Koistinen

Journal: Int J Cancer

PubMed ID: 37139608

Doi: 10.1002/ijc.34551

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Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma

Authors: Chengcheng Zhang, Linling Wang, Qianzhen Zhang, Junjie Shen, Xia Huang, Meiling Wang, Yi Huang, Jun Chen, Yanmin Xu, Wenxu Zhao, Yanan Qi, Yunyan Li, Yanjiao Ou, Zhi Yang, Cheng Qian

Journal: Front Immunol

PubMed ID: 37304295

Doi: 10.3389/fimmu.2023.1182409

Products & Services: Insect Expression

Molecular cloning and in silico analysis of chalcone isomerase from Polygonum minus

Authors: Fatin Lyana Azman Shah, Syarul Nataqain Baharum, Hoe-Han Goh, Thean Chor Leow, Ahmad Bazli Ramzi, Siti Nurbaya Oslan, Suriana Sabri

Journal: Mol Biol Rep

PubMed ID: 37148413

Doi: 10.1007/s11033-023-08417-1

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Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex

Authors: Mandy S M Wan, Reyhan Muhammad, Marios G Koliopoulos, Theodoros I Roumeliotis, Jyoti S Choudhary, Claudio Alfieri

Journal: Nature Communications

PubMed ID: 37137925

Doi: 10.1038/s41467-023-38276-0

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KREH1 RNA helicase activity promotes utilization of initiator gRNAs across multiple mRNAs in trypanosome RNA editing

Authors: Ashutosh P Dubey, Brianna L Tylec, Amartya Mishra, Katherine Sortino, Runpu Chen, Yijun Sun, Laurie K Read

Journal: Nucleic Acids Research

PubMed ID: 37140035

Doi: doi.org/10.1093/nar/gkad292

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BcMYB111 Responds to BcCBF2 and Induces Flavonol Biosynthesis to Enhance Tolerance under Cold Stress in Non-Heading Chinese Cabbage

Authors: Xiaoshan Chen , Ying Wu , Zhanghong Yu , Zhanyuan Gao , Qiang Ding , Sayyed Hamad Ahmad Shah , Wenyuan Lin , Ying Li , Xilin Hou

Journal: Int J Mol Sci .

PubMed ID: 37240015

Doi: 10.3390/ijms24108670

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Engineered ketocarotenoid biosynthesis in the polyextremophilic red microalga Cyanidioschyzon merolae 10D

Authors: Mark Seger , Fakhriyya Mammadova , Melany Villegas-Valencia , Barbara ´ Bastos de Freitas , Clarissa Chang , Iona Isachsen , Haley Hemstreet , Fatimah Abualsaud , Malia Boring , Peter J. Lammers , Kyle J. Lauersen

Journal: Metabolic engineering communications

Doi: 10.1016/j.mec.2023.e00226

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Safety and Efficacy of Intravenous and Intrathecal Delivery of AAV9-Mediated ARSA in Minipigs

Authors: Aysilu Mullagulova , Alisa Shaimardanova , Valeriya Solovyeva , Yana Mukhamedshina , Daria Chulpanova , Alexander Kostennikov, Shaza Issa, Albert Rizvanov

Journal: Int J Mol Sci .

PubMed ID: 37298156

Doi: 10.3390/ijms24119204

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Ionic displacement of Ca by Pb in calmodulin is affected by arrhythmia-associated mutations

Authors: Valerio Marino, Giuditta Dal Cortivo, Daniele Dell'Orco

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 37201768

Doi: 10.1016/j.bbamcr.2023.119490

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FOSL2 promotes intertumoral infiltration of T cells and increases pathological complete response rates in locally advanced rectal cancer patients

Authors: Kailun Xu, Xiaoyang Yin, Biting Zhou, Xi Zheng, Hao Wang, Jing Chen, Xue Cai, Huanhuan Gao, Xiaoming Xu, Liuhong Wang, Li Shen, Tiannan Guo, Shu Zheng, Baosheng Li, Yingkuan Shao, Jian Wang

Journal: Cancer Letters

PubMed ID: 36997107

Doi: 10.1016/j.canlet.2023.216145

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Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy

Authors: Stavroula Dionysopoulou, Per Wikstrom, Claudio Bucolo, Giovanni Luca Romano, Vincenzo Micale, Richard Svensson, Dimitris Spyridakos, Niki Mastrodimou, Spiros Georgakis, Panayotis Verginis, Erik Walum, Kyriaki Thermos

Journal: Diabetes

PubMed ID: 36821829

Doi: 10.2337/db22-0515

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The Nucleocapsid Proteins of SARS-CoV-2 and Its Close Relative Bat Coronavirus RaTG13 Are Capable of Inhibiting PKR- and RNase L-Mediated Antiviral Pathways

Authors: Kyle LeBlanc, Jessie Lynch, Christine Layne, Robert Vendramelli, Angela Sloan, Nikesh Tailor, Yvon Deschambault, Fushun Zhang, Darwyn Kobasa, David Safronetz, Yan Xiang, Jingxin Cao

Journal: Microbiol Spectr

PubMed ID: 37154717

Doi: 10.1128/spectrum.00994-23

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Redundant actions of neuropeptides encoded by the dh-pban gene for larval color pattern formation in the oriental armyworm Mythimnaseparata

Authors: Yu Shirai, Hajime Ono, Takaaki Daimon

Journal: Insect Biochem Mol Biol

PubMed ID: 37146697

Doi: 10.1016/j.ibmb.2023.103955

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KRAS mutation-induced TOPK overexpression contributes to tumour progression in non-small cell lung cancer

Authors: Chang Cai, Shuo Yao, Yanmei Zou, Hui Lu, Xiuqiong Chen, Yali Wang, Kun Zheng, Feng Zhu, Yihua Wang, Hua Xiong, Junfei Zhu

Journal: J Cell Mol Med

PubMed ID: 37226642

Doi: 10.1111/jcmm.17640

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Detection of viral RNAs at ambient temperature via reporter proteins produced through the target-splinted ligation of DNA probes

Authors: Elizabeth A Phillips, Adam D Silverman, Aric Joneja, Michael Liu, Carl Brown, Paul Carlson, Christine Coticchia, Kristen Shytle, Alex Larsen, Nadish Goyal, Vincent Cai, Jason Huang, Jennifer E Hickey, Emily Ryan, Joycelynn Acheampong, Pradeep Ramesh, James J Collins, William J Blake

Journal: Nat Biomed Eng

PubMed ID: 37142844

Doi: 10.1038/s41551-023-01028-y

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Design and development of microformulations for rapid release of small molecules and oligonucleotides

Authors: T Brown, M Stanton, F Cros, S Cho, A Kiselyov

Journal: Eur J Pharm Sci

PubMed ID: 37220816

Doi: 10.1016/j.ejps.2023.106472

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