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Hyperoxia exposure upregulates Dvl-1 and activates Wnt/β-catenin signaling pathway in newborn rat lung

Authors: Yuting Zhu, Yawen Li, Weilai Jin, Zhengying Li, Le Zhang, Yuanyuan Fang, Yanyu Zhang

Journal: BMC Mol Cell Biol

PubMed ID: 36726071

Doi: 10.1186/s12860-023-00465-6

Products & Services: Catalog Peptides

Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM

Authors: Airah Javorsky, Janesha C Maddumage, Emily R R Mackie, Tatiana P Soares da Costa, Patrick O Humbert, Marc Kvansakul

Journal: The FEBS journal

PubMed ID: 36029163

Doi: 10.1111/febs.16607

Products & Services: Peptide Synthesis

Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination

Authors: Huasong Ai, Zebin Tong, Zhiheng Deng, Jiakun Tian, Liying Zhang, Maoshen Sun, Yunxiang Du, Ziyu Xu, Qiang Shi, Lujun Liang, Qingyun Zheng, Jia-Bin Li, Man Pan, and Lei Liu

Journal: Chem

Doi: 10.1016/j.chempr.2023.01.012

Products & Services: Gene Synthesis

Novel csuC-DNA nanovaccine based on chitosan candidate vaccine against infection with Acinetobacter baumannii

Authors: Eskandar Hosseinnezhad-Lazarjani, Abbas Doosti, Ali Sharifzadeh

Journal: Vaccine

PubMed ID: 36841724

Doi: 10.1016/j.vaccine.2023.02.046

Products & Services: Proteins, Expression, Isolation and Analysis

Cell-autonomous requirement for ACE2 across organs in lethal mouse SARS-CoV-2 infection

Authors: Alan T Tang, David W Buchholz, Katherine M Szigety, Brian Imbiakha, Siqi Gao, Maxwell Frankfurter, Min Wang, Jisheng Yang, Peter Hewins, Patricia Mericko-Ishizuka, N Adrian Leu, Stephanie Sterling, Isaac A Monreal, Julie Sahler, Avery August, Xuming Zhu, Kellie A Jurado, Mingang Xu, Edward E Morrisey, Sarah E Millar, Hector C Aguilar, Mark L Kahn

Journal: PLoS Biol

PubMed ID: 36745682

Doi: 10.1371/journal.pbio.3001989

Products & Services: Proteins, Expression, Isolation and Analysis

DNA aptamer-based affinity chromatography system for purification of recombinant proteins tagged with lysine tag

Authors: Klaudia Arciszewska, Ewa Kowalska, Filip Bartnicki, Piotr Bonarek, Agnieszka Katarzyna Banaś, Wojciech Strzałka

Journal: J Chromatogr A

PubMed ID: 36780846

Doi: 10.1016/j.chroma.2023.463846

Products & Services: Proteins, Expression, Isolation and Analysis

Transcriptional dynamics of maize leaves, pollens and ovules to gain insights into heat stress-related responses

Authors: Ashok Babadev Jagtap, Inderjit Singh Yadav, Yogesh Vikal, Umesh Preethi Praba, Navneet Kaur, Adeshpal Singh Gill, Gurmukh S Johal

Journal: Front Plant Sci

PubMed ID: 36875566

Doi: 10.3389/fpls.2023.1117136

Products & Services: PCR Cloning and Subcloning

Multicopy suppressor screens reveal convergent evolution of single-gene lysis proteins

Authors: Benjamin A Adler, Karthik Chamakura, Heloise Carion, Jonathan Krog, Adam M Deutschbauer, Ry Young, Vivek K Mutalik, Adam P Arkin

Journal: Nat Chem Biol

PubMed ID: 36805702

Doi: 10.1038/s41589-023-01269-7

Products & Services: Plasmid DNA Preparation

The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase

Authors: Carlo Rinaldi, Paolo Pizzul, Erika Casari, Marco Mangiagalli, Renata Tisi, Maria Pia Longhese

Journal: Nucleic Acids Res

PubMed ID: 36762474

Doi: 10.1093/nar/gkad062

Products & Services: Gene Synthesis

Ultrasensitive and point-of-care detection of plasma phosphorylated tau in Alzheimer's disease using colorimetric and surface-enhanced Raman scattering dual-readout lateral flow assay

Authors: Liding Zhang, Ying Su, Xiaohan Liang, Kai Cao, Qingming Luo, Haiming Luo

Journal: Nano Res

PubMed ID: 37223429

Doi: 10.1007/s12274-022-5354-4

Products & Services: Recombinant Proteins

The antibacterial activity and antibacterial mechanism analyses of an LRR-IG protein in the Chinese mitten crab, Eriocheir sinensis

Authors: Yi Zhang, Yunhui Bai, Qiao Shi, Bin Zhou, Mengqi Ni, Jinbin Zheng, Zhaoxia Cui

Journal: Int J Biol Macromol

PubMed ID: 36801302

Doi: 10.1016/j.ijbiomac.2023.123732

Products & Services: Proteins, Expression, Isolation and Analysis

The endogenous repertoire harbors self-reactive CD4 T cell clones that adopt a follicular helper T cell-like phenotype at steady state

Authors: Victoria Lee, Donald M Rodriguez, Nicole K Ganci, Sharon Zeng, Junting Ai, Jaime L Chao, Matthew T Walker, Christine H Miller, David E J Klawon, Mary H Schoenbach, Domenick E Kennedy, Mark Maienschein-Cline, Nicholas D Socci, Marcus R Clark, Peter A Savage

Journal: Nat Immunol

PubMed ID: 36759711

Doi: 10.1038/s41590-023-01425-0

Products & Services: Molecular Biology Reagents

Elephant TP53-RETROGENE 9 induces transcription-independent apoptosis at the mitochondria

Authors: Aidan J Preston, Aaron Rogers, Miranda Sharp, Gareth Mitchell, Cristhian Toruno, Brayden B Barney, Lauren N Donovan, Journey Bly, Ryan Kennington, Emily Payne, Anthony Iovino, Gabriela Furukawa, Rosann Robinson, Bahar Shamloo, Matthew Buccilli, Rachel Anders, Sarah Eckstein, Elizabeth A Fedak, Tanner Wright, Carlo C Maley, Wendy K Kiso, Dennis Schmitt, David Malkin, Joshua D Schiffman, Lisa M Abegglen

Journal: Cell Death Discov

PubMed ID: 36797268

Doi: 10.1038/s41420-023-01348-7

Products & Services: Molecular Biology Reagents

Soluble adenylyl cyclase coordinates intracellular pH homeostasis and biomineralization in calcifying cells of a marine animal

Authors: William Weijen Chang, Angus B Thies, Martin Tresguerres, Marian Y Hu

Journal: Am J Physiol Cell Physiol

PubMed ID: 36779665

Doi: 10.1152/ajpcell.00524.2022

Products & Services: Peptide Synthesis

DUX4 double whammy: The transcription factor that causes a rare muscular dystrophy also kills the precursors of the human nose

Authors: Kaoru Inoue, Hamed Bostan, MaKenna R Browne, Owen F Bevis, Carl D Bortner, Steven A Moore, Aaron A Stence, Negin P Martin, Shih-Heng Chen, Adam B Burkholder, Jian-Liang Li, Natalie D Shaw

Journal: Sci Adv

PubMed ID: 36800423

Doi: 10.1126/sciadv.abq7744

Products & Services: Monoclonal Antibody Services

A PEG-lipid-free COVID-19 mRNA vaccine triggers robust immune responses in mice

Authors: Min Li , Yixuan Huang , Jiacai Wu , Sanpeng Li , Miao Mei , Haixia Chen , Ning Wang , Weigang Wu , Boping Zhou , Xu Tan , Bin Li

Journal: Materials Horizons

PubMed ID: 36468425

Doi: 10.1039/D2MH01260J

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PERK recruits E-Syt1 at ER-mitochondria contacts for mitochondrial lipid transport and respiration

Authors: Maria Livia Sassano, Alexander R van Vliet, Ellen Vervoort, Sofie Van Eygen, Chris Van den Haute, Benjamin Pavie, Joris Roels, Johannes V Swinnen, Marco Spinazzi, Leen Moens, Kristina Casteels, Isabelle Meyts, Paolo Pinton, Saverio Marchi, Leila Rochin, Francesca Giordano, Blanca Felipe-Abrio, Patrizia Agostinis

Journal: J Cell Biol

PubMed ID: 36821088

Doi: 10.1083/jcb.202206008

Products & Services: Molecular Biology Reagents

Discovery of Novel Transketolase Epitopes and the Development of IgG-Based Tuberculosis Serodiagnostics

Authors: Jaya Talreja , Changya Peng , Tuan-Minh Nguyen , Sorin Draghici , Lobelia Samavati

Journal: Microbiology Spectrum

PubMed ID: 36651770

Doi: 10.1128/spectrum.03377-22

Products & Services: Peptide Synthesis Polyclonal Antibody Services

Planthopper salivary sheath protein LsSP1 contributes to manipulation of rice plant defenses

Authors: Hai-Jian Huang, Yi-Zhe Wang , Li-Li Li , Hai-Bin Lu, Jia-Bao Lu, Xin Wang , Zhuang-Xin Ye , Ze-Long Zhang, Yu-Juan He, Gang Lu , Ji-Chong Zhuo , Qian-Zhuo Mao , Zong-Tao Sun , Jian-Ping Chen, Jun-Min Li , Chuan-Xi Zhang

Journal: Nat Commun .

PubMed ID: 36759625

Doi: 10.1038/s41467-023-36403-5

Products & Services: Antibody Services

NRXN1 depletion in the medial prefrontal cortex induces anxiety-like behaviors and abnormal social phenotypes along with impaired neurite outgrowth in rat

Authors: Di Wu, Jiansheng Zhu, Lianghui You, Jingyu Wang, Sufen Zhang, Zhonghui Liu, Qu Xu, Xiaojie Yuan, Lei Yang, Wei Wang, Meiling Tong, Qin Hong, Xia Chi

Journal: J Neurodev Disord

PubMed ID: 36737720

Doi: 10.1186/s11689-022-09471-9

Products & Services: Molecular Biology Reagents

Novel fusion protein PK5-RL-Gal-3C inhibits hepatocellular carcinoma via anti-angiogenesis and cytotoxicity

Authors: Xiaoge Gao, Pin Jiang, Xiaohuan Wei, Wei Zhang, Jiwei Zheng, Shishuo Sun, Hong Yao, Xiangye Liu, Qing Zhang

Journal: BMC Cancer

PubMed ID: 36793021

Doi: 10.1186/s12885-023-10608-9

Products & Services: Molecular Biology Reagents

Inhibiting the transcription and replication of Ebola viruses by disrupting the nucleoprotein and VP30 protein interaction with small molecules

Authors: Yan-Hong Ma, Xu Hong, Fang Wu, Xin-Feng Xu, Rui Li, Jin Zhong, Yao-Qi Zhou, Shu-Wen Liu, Jian Zhan, Wei Xu

Journal: Acta Pharmacol Sin

PubMed ID: 36759643

Doi: 10.1038/s41401-023-01055-0

Products & Services: PCR Cloning and Subcloning

A bio-orthogonal linear ubiquitin probe identifies STAT3 as a direct substrate of OTULIN in glioblastoma

Authors: Xianli Du, Jing Pang, Bin Gu, Tian Si, Yan Chang, Tianqi Li, Min Wu, Zicheng Wang, Yuxia Wang, Jiannan Feng, Ning Wu, Jianghong Man, Huiyan Li, Ailing Li, Tong Zhang, Bo Wang, Xiaotao Duan

Journal: Nucleic Acids Res

PubMed ID: 36660824

Doi: 10.1093/nar/gkad002

Products & Services: Proteins, Expression, Isolation and Analysis

Transferrin Receptor Protein 1 Is an Entry Factor for Rabies Virus

Authors: Xinxin Wang, Zhiyuan Wen, Huizhen Cao, Jie Luo, Lei Shuai, Chong Wang, Jinying Ge, Xijun Wang, Zhigao Bu, Jinliang Wang

Journal: J Virol

PubMed ID: 36779762

Doi: 10.1128/jvi.01612-22

Products & Services: Proteins, Expression, Isolation and Analysis

Application of an electro elution system for direct purification of linear covalently closed DNA fragments

Authors: F Talebnia, D Pushparajah, S Chandrasekaran, S J Hersch, N Nafissi, R Slavcev

Journal: J Chromatogr B Analyt Technol Biomed Life Sci

PubMed ID: 36842293

Doi: 10.1016/j.jchromb.2023.123622

Products & Services: Molecular Biology Reagents

De novo assembled transcriptomics assisted label-free quantitative proteomics analysis reveals sex-specific proteins in the intestinal tissue of Haemaphysalis qinghaiensis

Authors: Hejia Ma, Eloiza May Galon, Yanjun Lao, Ming Kang, Xuenan Xuan, Jixu Li, Yali Sun

Journal: Infect Genet Evol

PubMed ID: 36773671

Doi: 10.1016/j.meegid.2023.105409

Products & Services: PCR Cloning and Subcloning

Reaction intensification for biocatalytic production of polyphenolic natural product di-C-β-glucosides

Authors: Tuo Li, Annika J E Borg, Leo Krammer, Rolf Breinbauer, Bernd Nidetzky

Journal: Biotechnol Bioeng

PubMed ID: 36787984

Doi: 10.1002/bit.28354

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The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex

Authors: Zeyuan Guan, Juan Chen, Ruiwen Liu, Yanke Chen, Qiong Xing, Zhangmeng Du, Meng Cheng, Jianjian Hu, Wenhui Zhang, Wencong Mei, Beijing Wan, Qiang Wang, Jie Zhang, Peng Cheng, Huanyu Cai, Jianbo Cao, Delin Zhang, Junjie Yan, Ping Yin, Michael Hothorn, Zhu Liu

Journal: Nat Commun

PubMed ID: 36759618

Doi: 10.1038/s41467-023-36466-4

Products & Services: Peptide Synthesis

Chromium exposure altered metabolome and microbiome-associated with neurotoxicity in zebrafish

Authors: Tongtong Yan, Yawen Xu, Yuqi Zhu, Ping Jiang, Zhan Zhang, Lei Li, Qian Wu

Journal: J Appl Toxicol

PubMed ID: 36727205

Doi: 10.1002/jat.4440

Products & Services: Gene Synthesis

Delivery of spike-RBD by bacterial type three secretion system for SARS-CoV-2 vaccine development

Authors: Yuchen Zhou, Jing Qu, Xiaomeng Sun, Zhuo Yue, Yingzi Liu, Keli Zhao, Fan Yang, Jie Feng, Xiaolei Pan, Yongxin Jin, Zhihui Cheng, Liang Yang, Un-Hwan Ha, Weihui Wu, Liang Li, Fang Bai

Journal: Front Immunol

PubMed ID: 36895557

Doi: 10.3389/fimmu.2023.1129705

Products & Services: Recombinant Proteins

Fragment-Based Phasing of Peptidic Nanocrystals by MicroED

Authors: Logan S Richards, Maria D Flores, Claudia Millán, Calina Glynn, Chih-Te Zee, Michael R Sawaya, Marcus Gallagher-Jones, Rafael J Borges, Isabel Usón, Jose A Rodriguez

Journal: ACS Bio Med Chem Au

PubMed ID: 37096030

Doi: 10.1021/acsbiomedchemau.2c00082

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The cytomegalovirus gB/MF59 vaccine candidate induces antibodies against an antigenic domain controlling cell-to-cell spread

Authors: A C Gomes, I A Baraniak, A Lankina, Z Moulder, P Holenya, C Atkinson, G Tang, T Mahungu, F Kern, P D Griffiths, M B Reeves

Journal: Nat Commun

PubMed ID: 36823200

Doi: 10.1038/s41467-023-36683-x

Products & Services: Gene Synthesis

Analysis of Bacterial Microcompartments and Shell Protein Superstructures by Confocal Microscopy

Authors: Daniel S Trettel, Wade C Winkler

Journal: Microbiol Spectr

PubMed ID: 36786617

Doi: 10.1128/spectrum.03357-22

Products & Services: Peptide Synthesis

Mindin Activates Autophagy for Lipid Utilization and Facilitates White Spot Syndrome Virus Infection in Shrimp

Authors: Jie Gao, Ye-Jia Song, Hao Wang, Bao-Rui Zhao, Xian-Wei Wang

Journal: MBio

PubMed ID: 36779788

Doi: 10.1128/mbio.02919-22

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N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on α-dystroglycan and prevents muscular dystrophy

Authors: Hidehiko Okuma, Jeffrey M Hord, Ishita Chandel, David Venzke, Mary E Anderson, Ameya S Walimbe, Soumya Joseph, Zeita Gastel, Yuji Hara, Fumiaki Saito, Kiichiro Matsumura, Kevin P Campbell

Journal: Elife

PubMed ID: 36723429

Doi: 10.7554/eLife.82811

Products & Services: Combinatorial DNA Libraries

Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening

Authors: Ling Deng, Li Yang, Shuhan Zhu, Man Li, Yu Wang, Xiaolong Cao, Qiongyao Wang, Linlang Guo

Journal: Cell Death Discov

PubMed ID: 36725843

Doi: 10.1038/s41420-023-01315-2

Products & Services: Molecular Biology Reagents

Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes

Authors: Amanda Fabra-García, Sophia Hailemariam, Roos M de Jong, Kirsten Janssen, Karina Teelen, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Danton Ivanochko, Anthony Semesi, Brandon McLeod, Martijn W Vos, Marloes H C de Bruijni, Judith M Bolscher, Marta Szabat, Stefanie Vogt, Lucas Kraft, Sherie Duncan, Moses R Kamya, Margaret E Feeney, Prasanna Jagannathan, Bryan Greenhouse, Koen J Dechering, Robert W Sauerwein, C Richter King, Randall S MacGill, Teun Bousema, Jean-Philippe Julien, Matthijs M Jore

Journal: Immunity

PubMed ID: 36792574

Doi: 10.1016/j.immuni.2023.01.009

Products & Services: Proteins, Expression, Isolation and Analysis

Cas9-orthologue-mediated cytosine and adenine base editors recognizing NNAAAA PAM sequences

Authors: Min Li, Yuting Zhao, Xiaowen Xue, Jingli Zhong, Jianxiang Lin, Jiankui Zhou, Wenhua Yu, Jun Chen, Yunbo Qiao

Journal: Biotechnol J

PubMed ID: 36800529

Doi: 10.1002/biot.202200533

Products & Services: Proteins, Expression, Isolation and Analysis

Using a modified piggyBac transposon-combined Cre/loxP system to produce selectable reporter-free transgenic bovine mammary epithelial cells for somatic cell nuclear transfer

Authors: Guangdong Hu, Meijun Song, Yan Wang, Kexing Hao, Jing Wang, Yong Zhang

Journal: Genesis

PubMed ID: 36748563

Doi: 10.1002/dvg.23510

Products & Services: Proteins, Expression, Isolation and Analysis

Recombinant vesicular stomatitis virus-vectored vaccine induces long-lasting immunity against Nipah virus disease

Authors: Courtney Woolsey, Viktoriya Borisevich, Alyssa C Fears, Krystle N Agans, Daniel J Deer, Abhishek N Prasad, Rachel O'Toole, Stephanie L Foster, Natalie S Dobias, Joan B Geisbert, Karla A Fenton, Robert W Cross, Thomas W Geisbert

Journal: J Clin Invest

PubMed ID: 36445779

Doi: 10.1172/JCI164946

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Chimeric Hepatitis B core virus-like particles harboring SARS-CoV2 epitope elicit a humoral immune response in mice

Authors: Sima Sazegari, Malihe Akbarzadeh Niaki, Alireza Afsharifar, Ali Niazi, Abdollah Derakhshandeh, Maryam Moradi Vahdat, Farshad Hemmati, Mohammad Hadi Eskandari

Journal: Microb Cell Fact

PubMed ID: 36841778

Doi: 10.1186/s12934-023-02043-z

Products & Services: PCR Cloning and Subcloning

Evaluate the guide RNA effectiveness -mediated transient assays in

Authors: Zhibo Wang, Zachary Shea, Qi Li, Kunru Wang, Kerri Mills, Bo Zhang, Bingyu Zhao

Journal: Front Plant Sci

PubMed ID: 36890894

Doi: 10.3389/fpls.2023.1111683

Products & Services: Proteins, Expression, Isolation and Analysis

Whole genome sequencing of Malaysian colorectal cancer patients reveals specific druggable somatic mutations

Authors: Ryia Illani Mohd Yunos, Nurul-Syakima Ab Mutalib, Jia-Shiun Khoo, Sazuita Saidin, Muhiddin Ishak, Saiful Effendi Syafruddin, Francis Yew Fu Tieng, Najwa Farhah Md Yusof, Mohd Ridhwan Abd Razak, Norshahidah Mahamad Nadzir, Nadiah Abu, Isa Md Rose, Ismail Sagap, Luqman Mazlan, Rahman Jamal

Journal: Front Mol Biosci

PubMed ID: 36866106

Doi: 10.3389/fmolb.2022.997747

Products & Services: Stable Cell Lines

DhFIG_2, a gene of nematode-trapping fungus Dactylellina haptotyla that encodes a component of the low-affinity calcium uptake system, is required for conidiation and knob-trap formation

Authors: Xiaozhou Zhao, Yani Fan, Weiwei Zhang, Meichun Xiang, Seogchan Kang, Shunxian Wang, Xingzhong Liu

Journal: Fungal Genet Biol

PubMed ID: 36849068

Doi: 10.1016/j.fgb.2023.103782

Products & Services: Gene Synthesis

Lipid-induced alteration in retinoic acid signaling leads to mitochondrial dysfunction in HepG2 and Huh7 cells

Authors: Eshani Karmakar, Nabanita Das, Bidisha Mukherjee, Prosenjit Das, Satinath Mukhopadhyay, Sib Sankar Roy

Journal: Biochem Cell Biol

PubMed ID: 36787544

Doi: 10.1139/bcb-2022-0266

Products & Services: PCR Cloning and Subcloning

BioID2 screening identifies KIAA1671 as an EPS8 proximal factor that marks sites of microvillus growth

Authors: Isabella M Gaeta, Matthew J Tyska

Journal: Mol Biol Cell

PubMed ID: 36790915

Doi: 10.1091/mbc.E22-11-0498

Products & Services: Gene Synthesis

Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment

Authors: Robin M Hallett, Ester Bonfill-Teixidor, Raffaella Iurlaro, Alexandra Arias, Swetha Raman, Peter Bayliss, Olga Egorova, Almudena Neva-Alejo, Aj Robert McGray, Esther Lau, Alexandre Bosch, Melissa Beilschmidt, Dorothea Maetzel, Johan Fransson, Isabel Huber-Ruano, Judit Anido, Jean-Philippe Julien, Patricia Giblin, Joan Seoane

Journal: Clin Cancer Res

PubMed ID: 36441800

Doi: 10.1158/1078-0432.CCR-21-1888

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Exocytic machineries differentially control mediator release from allergen-triggered RBL-2H3 cells

Authors: Pratikshya Adhikari, Tolulope E Ayo, John C Vines, Shuzo Sugita, Hao Xu

Journal: Inflamm Res

PubMed ID: 36725743

Doi: 10.1007/s00011-023-01698-z

Products & Services: Proteins, Expression, Isolation and Analysis

Mechanism of inhibition of CRISPR-Cas9 by anti-CRISPR protein AcrIIC1

Authors: Yalan Zhu, Sen Yin, Zhao Li

Journal: Biochem Biophys Res Commun

PubMed ID: 36878037

Doi: 10.1016/j.bbrc.2023.02.065

Products & Services: Molecular Biology Reagents

Non-specific and specific DNA binding modes of bacterial histone, HU, separately regulate distinct physiological processes through different mechanisms

Authors: Subhash C Verma, Adam Harned, Kedar Narayan, Sankar Adhya

Journal: Mol Microbiol

PubMed ID: 36708073

Doi: 10.1111/mmi.15033

Products & Services: Proteins, Expression, Isolation and Analysis

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