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页码: 196/1026 每页显示数量

Dissecting Out the Molecular Mechanism of Insecticidal Activity of Ostreolysin A6/Pleurotolysin B Complexes on Western Corn Rootworm

Authors: Matej Milijaš Jotić, Anastasija Panevska, Ioan Iacovache, Rok Kostanjšek, Martina Mravinec, Matej Skočaj, Benoît Zuber, Ana Pavšič, Jaka Razinger, Špela Modic, Francesco Trenti, Graziano Guella, Kristina Sepčić

Journal: Toxins (Basel)

PubMed ID: 34209983

Doi: 10.3390/toxins13070455

Products & Services: Plasmid DNA Preparation

The local anesthetic ropivacaine suppresses progression of breast cancer by regulating miR-27b-3p/YAP axis

Authors: Lu Zhao, Shuang Han, Junde Hou, Wenhui Shi, Yonglei Zhao, Yongxue Chen

Journal: Aging (Albany NY)

PubMed ID: 34126594

Doi: 10.18632/aging.203160

Products & Services: Plasmid DNA Preparation

Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation

Authors: Sandra Torres, Estel Solsona-Vilarrasa, Susana Nuñez, Nuria Matías, Naroa Insausti-Urkia, Fernanda Castro, Mireia Casasempere, Gemma Fabriás, Josefina Casas, Carlos Enrich, José C Fernández-Checa, Carmen Garcia-Ruiz

Journal: Redox Biol

PubMed ID: 34175669

Doi: 10.1016/j.redox.2021.102052

Products & Services: Plasmid DNA Preparation

Allelic diversification after transposable element exaptation promoted as the master sex determining gene of sablefish

Authors: Amaury Herpin, Manfred Schartl, Alexandra Depincé, Yann Guiguen, Julien Bobe, Aurélie Hua-Van, Edward S Hayman, Anna Octavera, Goro Yoshizaki, Krista M Nichols, Giles W Goetz, J Adam Luckenbach

Journal: Genome Res

PubMed ID: 34183453

Doi: 10.1101/gr.274266.120

Products & Services: PCR Cloning and Subcloning

Self-assembled small messenger RNA nanospheres for efficient therapeutic apoptin expression and synergistic Gene-Chemotherapy of breast cancer

Authors: Yuxia Tang, Xiang Liao, Chunyan Wang, Ying Liu, Jing Pan, Ying Tian, Zhaogang Teng, Guangming Lu

Journal: J Colloid Interface Sci

PubMed ID: 34192626

Doi: 10.1016/j.jcis.2021.06.061

Products & Services: PCR Cloning and Subcloning

MiR-513b-5p represses autophagy during the malignant progression of hepatocellular carcinoma by targeting PIK3R3

Authors: Wei Jin, Yilei Liang, Shuyou Li, Guoxiang Lin, Haiying Liang, Zhenni Zhang, Weiming Zhang, Rongjun Nie

Journal: Aging (Albany NY)

PubMed ID: 34120890

Doi: 10.18632/aging.203135

Products & Services: Molecular Biology Reagents

Mulberroside A repairs high fructose diet-induced damage of intestinal epithelial and blood-brain barriers in mice: A potential for preventing hippocampal neuroinflammatory injury

Authors: Yu R,Wen S,Wang Q,Wang C,Zhang L,Wu X,Li J,Kong L

Journal: Journal of neurochemistry

PubMed ID: 33205422

Doi: 10.1111/jnc.15242

Products & Services: Endotoxin Detection & Removal System

Inherent backbone dynamics fine-tune the functional plasticity of Tudor domains

Authors: Ashish A Kawale, Björn M Burmann

Journal: Structure

PubMed ID: 34197736

Doi: 10.1016/j.str.2021.06.007

Products & Services: Custom Vector Construction

Design, synthesis, biological evaluation and structural characterization of novel GEBR library PDE4D inhibitors

Authors: Chiara Brullo, Federica Rapetti, Sara Abbate, Tommaso Prosdocimi, Archimede Torretta, Marta Semrau, Matteo Massa, Silvana Alfei, Paola Storici, Emilio Parisini, Olga Bruno

Journal: Eur J Med Chem

PubMed ID: 34171658

Doi: 10.1016/j.ejmech.2021.113638

Products & Services: Codon Optimization

A stealth antigen SPESP1, which is epigenetically silenced in tumors, is a suitable target for cancer immunotherapy

Authors: Akemi Kosaka, Yuki Yajima, Mayumi Hatayama, Katsuya Ikuta, Takaaki Sasaki, Noriko Hirai, Syunsuke Yasuda, Marino Nagata, Ryusuke Hayashi, Shohei Harabuchi, Kenzo Ohara, Mizuho Ohara, Takumi Kumai, Kei Ishibashi, Yui Hirata-Nozaki, Toshihiro Nagato, Kensuke Oikawa, Yasuaki Harabuchi, Esteban Celis, Toshikatsu Okumura, Yoshinobu Ohsaki, Hiroya Kobayashi, Takayuki Ohkuri

Journal: Cancer Sci

PubMed ID: 34009705

Doi: 10.1111/cas.14973

Products & Services: Catalog Peptides

Pharmacokinetics, Immunogenicity and Safety Study for SHR-1309 Injection and Perjeta® in Healthy Chinese Male Volunteers

Authors: Yingzi Cui, Dongyang Cui, Xinran Ren, Xuesong Chen, Guangwen Liu, Zhengzhi Liu, Yanli Wang, Xinyao Qu, Yicheng Zhao, Haimiao Yang

Journal: Front Pharmacol

PubMed ID: 34149414

Doi: 10.3389/fphar.2021.660541

Products & Services: Catalog Antibody

Unbiased profiling of CRISPR RNA-guided transposition products by long-read sequencing

Authors: Phuc Leo H Vo, Christopher Acree, Melissa L Smith, Samuel H Sternberg

Journal: Mob DNA

PubMed ID: 34103093

Doi: 10.1186/s13100-021-00242-2

Products & Services: Gene Synthesis

Cellulosome Localization Patterns Vary across Life Stages of Anaerobic Fungi

Authors: Stephen P Lillington, William Chrisler, Charles H Haitjema, Sean P Gilmore, Chuck R Smallwood, Vaithiyalingam Shutthanandan, James E Evans, Michelle A O'Malley

Journal: MBio

PubMed ID: 34061594

Doi: 10.1128/mBio.00832-21

Products & Services: Gene Synthesis

Nuclear factor kappa B inhibitor suppresses experimental autoimmune neuritis in mice via declining macrophages polarization to M1 type

Authors: Donghui Shen, Fengna Chu, Yue Lang, Chao Zheng, Chunrong Li, Kangding Liu, Jie Zhu

Journal: Clin Exp Immunol

PubMed ID: 34118070

Doi: 10.1111/cei.13637

Products & Services: Peptide Synthesis

Identification of testicular Foxq1 as a critical modulator of lactate metabolism in mouse Sertoli cells

Authors: Zetao Liu, Mingyou Yuan, Xiangxiang Meng, Haiwen Bie, Shaobo Yao

Journal: Histochem Cell Biol

PubMed ID: 34091745

Doi: 10.1007/s00418-021-01994-x

Products & Services: Gene Synthesis

Mummichog gill and operculum exhibit functionally consistent claudin-10 paralog profiles and Claudin-10c hypersaline response

Authors: Chun Chih Chen, William S Marshall, George N Robertson, Regina R F Cozzi, Scott P Kelly

Journal: Biol Open

PubMed ID: 34156063

Doi: 10.1242/bio.058868

Products & Services: Polyclonal Antibody Services

Multi-locus sequence typing analysis of Mycoplasma synoviae isolates reveals unique sequence types in China

Authors: Xiaorong Zhang, Yang Chen, Di Xie, Mengjiao Guo, Shuang Ma, Mengyao Chen, Dianfeng Chu, Yantao Wu

Journal: Vet Microbiol

PubMed ID: 34166888

Doi: 10.1016/j.vetmic.2021.109101

Products & Services: Gene Synthesis

The Rac-GAP alpha2-chimaerin signals via CRMP2 and stathmins in the development of the ocular motor system

Authors: Luis Carretero-Rodriguez, Ragnheiður Guðjónsdóttir, Ivana Poparic, Madeline Louise Reilly, Mary Chol, Isaac H Bianco, Marco Chiapello, Renata Feret, Michael J Deery, Sarah Guthrie

Journal: J Neurosci

PubMed ID: 34168008

Doi: 10.1523/JNEUROSCI.0983-19.2021

Products & Services: Gene Synthesis

Human platelet lysate biotherapy for traumatic brain injury: preclinical assessment

Authors: Ouada Nebie, Kevin Carvalho, Lassina Barro, Liling Delila, Emilie Faivre, Ting-Yi Renn, Ming-Li Chou, Yu-Wen Wu, Ariunjargal Niem-Redene, Szu-Yi Chou, Luc Buée, Chaur-Jong Hu, Chih-Wei Peng, David Devos, David Blum, Thierry Burnouf

Journal: Brain

PubMed ID: 34086871

Doi: 10.1093/brain/awab205

Products & Services: Polyclonal Antibody Services

MiR-379-5p targets microsomal glutathione transferase 1 (MGST1) to regulate human glioma in cell proliferation, migration and invasion and epithelial-mesenchymal transition (EMT)

Authors: Baoyi Yang, Shitao Xia, Xiangmei Ye, Wei Jing, Beifeng Wu

Journal: Biochem Biophys Res Commun

PubMed ID: 34171541

Doi: 10.1016/j.bbrc.2021.05.099

Products & Services: Recombinant Proteins

Immune and experimental infection responses of dairy cows vaccinated with the combination of six Staphylococcus aureus proteins that are expressed during bovine intramammary infection and a triple adjuvant

Authors: Céline Ster, Marianne Allard, Julie Côté-Gravel, Simon Boulanger, Pierre Lacasse, François Malouin

Journal: Vet Immunol Immunopathol

PubMed ID: 34217108

Doi: 10.1016/j.vetimm.2021.110290

Products & Services: Catalog Antibody

Oral Delivery of Expressing Chicken NK-2 Peptide Protects Against Infection in Broiler Chickens

Authors: Samiru S Wickramasuriya, Inkyung Park, Youngsub Lee, Woo H Kim, Chris Przybyszewski, Cyril G Gay, Jolieke G van Oosterwijk, Hyun S Lillehoj

Journal: Front Vet Sci

PubMed ID: 34150899

Doi: 10.3389/fvets.2021.684818

Products & Services: Recombinant Proteins

Development and Validation of a Simoa Assay for Determination of Recombinant Batroxobin in Human Serum

Authors: Bian-Zhen Wang, Meng-Jia Wang, Min-Rui Wang, Lun Ou, Li-Hou Dong, Kelly Dong, Hai-Feng Song

Journal: Curr Med Sci

PubMed ID: 34169424

Doi: 10.1007/s11596-021-2382-6

Products & Services: Monoclonal Antibody Services

Improved diagnosis of SARS-CoV-2 by using nucleoprotein and spike protein fragment 2 in quantitative dual ELISA tests

Authors: Carolina De Marco Verissimo, Carol O'Brien, Jesús López Corrales, Amber Dorey, Krystyna Cwiklinski, Richard Lalor, Jack M Doyle, Stephen Field, Claire Masterson, Eduardo Ribes Martinez, Gerry Hughes, Colm Bergin, Kieran Walshe, Bairbre McNicholas, John G Laffey, John P Dalton, Colm Kerr, Sean Doyle

Journal: Epidemiol Infect

PubMed ID: 34099081

Doi: 10.1017/S0950268821001308

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Phospho-β-catenin expression in primary and metastatic melanomas and in tumor-free visceral tissues, and associations with expression of PD-L1 and PD-L2

Authors: Joel Pinczewski, Rebecca C Obeng, Craig L Slingluff, Victor H Engelhard

Journal: Pathol Res Pract

PubMed ID: 34167064

Doi: 10.1016/j.prp.2021.153527

Products & Services: Peptide Synthesis

Synthetic conjugate peptide Fba-Met6 (MP12) induces complement-mediated resistance against disseminated Candida albicans

Authors: Abby L Adams, Karen Eberle, Jonothan Rosario Colón, Evan Courville, Hong Xin

Journal: Vaccine

PubMed ID: 34127293

Doi: 10.1016/j.vaccine.2021.06.001

Products & Services: Mammalian Expression

Spatial distribution of immune checkpoint proteins in histological subtypes of lung adenocarcinoma

Authors: Sarah Müller, Stefanie Mayer, Peter Möller, Thomas F E Barth, Ralf Marienfeld

Journal: Neoplasia

PubMed ID: 34102454

Doi: 10.1016/j.neo.2021.05.005

Products & Services: Gene Synthesis

Identification and validation of T-cell receptors targeting RAS hot-spot mutations in human cancers for use in cell-based immunotherapy

Authors: Noam Levin, Biman C Paria, Nolan R Vale, Rami Yoseph, Frank J Lowery, Maria R Parkhurst, Zhiya Yu, Maria Florentin, Gal Cafri, Jared J Gartner, Mackenzie L Shindorf, Lien T Ngo, Satyajit Ray, Sanghyun P Kim, Amy R Copeland, Paul F Robbins, Steven A Rosenberg

Journal: Clin Cancer Res

PubMed ID: 34168045

Doi: 10.1158/1078-0432.CCR-21-0849

Products & Services: Gene Synthesis

Identification of a protein unique to the genus Plasmodium that contains a WD40 repeat domain and extensive low-complexity sequence

Authors: Gladys T Cortés, Martha Margarita Gonzalez Beltran, Claudio J Gómez-Alegría, Mark F Wiser

Journal: Parasitol Res

PubMed ID: 34142223

Doi: 10.1007/s00436-021-07190-z

Products & Services: DNA Sequencing

CyDisCo production of functional recombinant SARS-CoV-2 spike receptor binding domain

Authors: Janani Prahlad, Lucas R Struble, William E Lutz, Savanna A Wallin, Surender Khurana, Andy Schnaubelt, Mara J Broadhurst, Kenneth W Bayles, Gloria E O Borgstahl

Journal: Protein Sci

PubMed ID: 34191362

Doi: 10.1002/pro.4152

Products & Services: Nucleic Acid Purification & Analysis

mTORC2 regulates ribonucleotide reductase to promote DNA replication and gemcitabine resistance in non-small cell lung cancer

Authors: Ling Tian, Congcong Chen, Yanguan Guo, Fan Zhang, Jinye Mi, Qi Feng, Shengbin Lin, Naite Xi, Jiaxin Tian, Li Yu, Yan Chen, Mingrong Cao, Caiyong Lai, Jun Fan, Yongchang Zhang, Guo Chen

Journal: Neoplasia

PubMed ID: 34126361

Doi: 10.1016/j.neo.2021.05.007

Products & Services: Plasmid DNA Preparation

An updated RT-qPCR assay for the simultaneous detection and quantification of chikungunya, dengue and zika viruses

Authors: Diego Alejandro Álvarez-Díaz, Emmanuel Valencia-Álvarez, Jorge Alonso Rivera, Aura Caterine Rengifo, José Aldemar Usme-Ciro, Dioselina Peláez-Carvajal, Yenny Yolanda Lozano-Jiménez, Orlando Torres-Fernández

Journal: Infect Genet Evol

PubMed ID: 34116240

Doi: 10.1016/j.meegid.2021.104967

Products & Services: Gene Synthesis

Novel neuroprotective peptides in the venom of the solitary scoliid wasp

Authors: Carlos Alberto-Silva, Fernanda Calheta Vieira Portaro, Roberto Tadashi Kodama, Halyne Queiroz Pantaleão, Marisa Rangel, Ken-Ichi Nihei, Katsuhiro Konno

Journal: J Venom Anim Toxins Incl Trop Dis

PubMed ID: 34194483

Doi: 10.1590/1678-9199-JVATITD-2020-0171

Products & Services: Peptide Synthesis

Improvement in extracellular secretion of recombinant L-asparaginase II by Escherichia coli BL21 (DE3) using glycine and n-dodecane

Authors: Juan Carlos Flores-Santos, Ignacio S Moguel, Gisele Monteiro, Adalberto Pessoa, Michele Vitolo

Journal: Braz J Microbiol

PubMed ID: 34100260

Doi: 10.1007/s42770-021-00534-y

Products & Services: Gene Synthesis

H, C, N backbone and side-chain NMR assignments of the C-terminal domain of Mycobacterium Tuberculosis ribosome maturation factor RimM

Authors: Haoran Zhang, Chenyun Guo, Donghai Lin

Journal: Biomol NMR Assign

PubMed ID: 34101143

Doi: 10.1007/s12104-021-10032-9

Products & Services: Gene Synthesis

Structural and biochemical characterization of a novel ZntB (CmaX) transporter protein from Pseudomonas aeruginosa

Authors: Artem Stetsenko, Pavlo Stehantsev, Natalia O Dranenko, Mikhail S Gelfand, Albert Guskov

Journal: Int J Biol Macromol

PubMed ID: 34175341

Doi: 10.1016/j.ijbiomac.2021.06.130

Products & Services: Gene Synthesis

Bergamottin Induces DNA Damage and Inhibits Malignant Progression in Melanoma by Modulating miR-145/Cyclin D1 Axis

Authors: Zhongfang Zhao, Nong Liao

Journal: Onco Targets Ther

PubMed ID: 34168462

Doi: 10.2147/OTT.S275322

Products & Services: Gene Synthesis

SARS-CoV-2 Serologic Assays Dependent on Dual-Antigen Binding Demonstrate Diverging Kinetics Relative to Other Antibody Detection Methods

Authors: Elitza S Theel, Patrick W Johnson, Katie L Kunze, Liang Wu, Amy P Gorsh, Dane Granger, Matthew M Roforth, Calvin R Jerde, Michael Lasho, Kylie J Andersen, Brenna M Murphy, Julie Harring, Douglas F Lake, Sergei A Svarovsky, Jonathon W Senefeld, Rickey E Carter, Michael J Joyner, Nikola A Baumann, John R Mills

Journal: J Clin Microbiol

PubMed ID: 34166066

Doi: 10.1128/JCM.01231-21

Products & Services: Protein Reagents and Products

Phage vB_PaeS-PAJD-1 Rescues Murine Mastitis Infected With Multidrug-Resistant

Authors: Zhaofei Wang, Yibing Xue, Ya Gao, Mengting Guo, Yuanping Liu, Xinwei Zou, Yuqiang Cheng, Jingjiao Ma, Hengan Wang, Jianhe Sun, Yaxian Yan

Journal: Front Cell Infect Microbiol

PubMed ID: 34178726

Doi: 10.3389/fcimb.2021.689770

Products & Services: Polyclonal Antibody Services

Castration-Induced Downregulation of SPARC in Stromal Cells Drives Neuroendocrine Differentiation of Prostate Cancer

Authors: Claudia Enriquez, Valeria Cancila, Renata Ferri, Roberta Sulsenti, Irene Fischetti, Matteo Milani, Paola Ostano, Ilaria Gregnanin, Maurizia Mello-Grand, Enrico Berrino, Marco Bregni, Giuseppe Renne, Claudio Tripodo, Mario P Colombo, Elena Jachetti

Journal: Cancer Res

PubMed ID: 34185677

Doi: 10.1158/0008-5472.CAN-21-0163

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Cell-Surface-Specific Monoclonal Antibodies Protect Mice against Invasive Infection

Authors: Jonothan Rosario-Colon, Karen Eberle, Abby Adams, Evan Courville, Hong Xin

Journal: Int J Mol Sci

PubMed ID: 34200478

Doi: 10.3390/ijms22116162

Products & Services: ORF cDNA Clones/MolecularCloud

Distinct responses of human peripheral blood cells to different misfolded protein oligomers

Authors: Magdalena Leal-Lasarte, Benedetta Mannini, Fabrizio Chiti, Michele Vendruscolo, Christopher M Dobson, Cintia Roodveldt, David Pozo

Journal: Immunology

PubMed ID: 34043816

Doi: 10.1111/imm.13377

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Inhibition of the 3CL Protease and SARS-CoV-2 Replication by Dalcetrapib

Authors: Eric J Niesor, Guy Boivin, Eric Rhéaume, Rong Shi, Véronique Lavoie, Nathalie Goyette, Marie-Eve Picard, Anne Perez, Fouzia Laghrissi-Thode, Jean-Claude Tardif

Journal: ACS Omega

PubMed ID: 34235330

Doi: 10.1021/acsomega.1c01797

Products & Services: Proteins, Expression, Isolation and Analysis

Characterization of an Atypical Hsp70 Demonstrates Its Cytosolic-Nuclear Localization and Modulation by Quercetin and Methylene Blue

Authors: Adélle Burger, Paula Macucule-Tinga, Stephen John Bentley, Michael Hans Ludewig, Ndumiso Nhlakanipho Mhlongo, Addmore Shonhai, Aileen Boshoff

Journal: Int J Mol Sci

PubMed ID: 34202520

Doi: 10.3390/ijms22136776

Products & Services: Codon Optimization

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

Authors: Taylor R Jamieson, Joanna Poutou, Ricardo Marius, Xiaohong He, Reza Rezaei, Taha Azad, Carolina S Ilkow

Journal: J Vis Exp

PubMed ID: 34152313

Doi: 10.3791/62486

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a Mini-Replicon-Based Reverse-Genetics System for Rice Stripe Tenuivirus

Authors: Mingfeng Feng, Luyao Li, Ruixiang Cheng, Yulong Yuan, Yongxin Dong, Minglong Chen, Rong Guo, Min Yao, Yi Xu, Yijun Zhou, Jianxiang Wu, Xin Shun Ding, Xueping Zhou, Xiaorong Tao

Journal: J Virol

PubMed ID: 33952642

Doi: 10.1128/JVI.00589-21

Products & Services: Codon Optimization

Identification of a dual orange/far-red and blue light photoreceptor from an oceanic green picoplankton

Authors: Yuko Makita, Shigekatsu Suzuki, Keiji Fushimi, Setsuko Shimada, Aya Suehisa, Manami Hirata, Tomoko Kuriyama, Yukio Kurihara, Hidefumi Hamasaki, Emiko Okubo-Kurihara, Kazutoshi Yoshitake, Tsuyoshi Watanabe, Masaaki Sakuta, Takashi Gojobori, Tomoko Sakami, Rei Narikawa, Haruyo Yamaguchi, Masanobu Kawachi, Minami Matsui

Journal: Nat Commun

PubMed ID: 34135337

Doi: 10.1038/s41467-021-23741-5

Products & Services: PCR and Cloning

miR-24 controls the regenerative competence of hair follicle progenitors by targeting Plk3

Authors: Fengzhen Liu, Xia Zhang, You Peng, Liping Zhang, Yao Yu, Peng Hua, Peiying Zhu, Xinyu Yan, Yin Li, Liang Zhang

Journal: Cell Rep

PubMed ID: 34107258

Doi: 10.1016/j.celrep.2021.109225

Products & Services: ORF cDNA Clones/MolecularCloud

HIV-1 sequences in lentiviral vector genomes can be substantially reduced without compromising transduction efficiency

Authors: Helin Sertkaya, Mattia Ficarelli, Nathan P Sweeney, Hannah Parker, Conrad A Vink, Chad M Swanson

Journal: Sci Rep

PubMed ID: 34103612

Doi: 10.1038/s41598-021-91309-w

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Soluble Cytoplasmic Expression and Purification of Immunotoxin HER2(scFv)-PE24B as a Maltose Binding Protein Fusion

Authors: Sangsu Park, Minh Quan Nguyen, Huynh Kim Khanh Ta, Minh Tan Nguyen, Gunsup Lee, Chong Jai Kim, Yeon Jin Jang, Han Choe

Journal: Int J Mol Sci

PubMed ID: 34204265

Doi: 10.3390/ijms22126483

Products & Services: Endotoxin Detection & Removal System

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