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Differential DNA Methylation and Expression of miRNAs in Adipose Tissue From Twin Pairs Discordant for Type 2 Diabetes
Authors: Emma Nilsson, Magdalena Vavakova, Alexander Perfilyev, Johanna Säll, Per-Anders Jansson, Pernille Poulsen, Jonathan Lou S Esguerra, Lena Eliasson, Allan Vaag, Olga Göransson, Charlotte Ling
Journal: Diabetes
PubMed ID: 34315727
Doi: 10.2337/db20-0324
Products & Services: DNA Sequencing   
TRPC3 promotes tumorigenesis of gastric cancer via the CNB2/GSK3β/NFATc2 signaling pathway
Authors: Da-Cen Lin, Si-Yi Zheng, Zhi-Guang Zhang, Jian-Hua Luo, Zhuang-Li Zhu, Li Li, Lu-Shan Chen, Xinjian Lin, James S K Sham, Mo-Jun Lin, Rui-Xiang Zhou
Journal: Cancer Lett
PubMed ID: 34311033
Doi: 10.1016/j.canlet.2021.07.038
Products & Services: DNA Sequencing   
PARP-1 inhibition attenuates the inflammatory response in the cartilage of a rat model of osteoarthritis
Authors: Zili Liu, Honglin Wang, Shaoqian Wang, Jie Gao, Lei Niu
Journal: Bone Joint Res
PubMed ID: 34254815
Doi: 10.1302/2046-3758.107.BJR-2020-0200.R2
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CRISPR-/Cas12a-Mediated Liposome-Amplified Strategy for the Surface-Enhanced Raman Scattering and Naked-Eye Detection of Nucleic Acid and Application to Food Authenticity Screening
Authors: Jianghua Liu, Jiahui Chen, Di Wu, Mingquan Huang, Jian Chen, Ruiyuan Pan, Yongning Wu, Guoliang Li
Journal: Anal Chem
PubMed ID: 34278781
Doi: 10.1021/acs.analchem.1c01163
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Dual Targeting of Endoplasmic Reticulum by Redox-Deubiquitination Regulation for Cancer Therapy
Authors: Biao Cai, Mengfei Hou, Shijun Zhang, Zhixiang Xin, Jiwei Huang, Jingxing Yang, Yueming Wang, Xingyun Cai, Shaowei Xie, Chunfu Zhang, Yiran Huang
Journal: Int J Nanomedicine
PubMed ID: 34354353
Doi: 10.2147/IJN.S321612
Overexpressed MPS-1 contributes to endometrioma development through the NF-κB signaling pathway
Authors: Yang Liu, Junyan Ma, Liqi Zhang, Jun Lin, Xiaohua Liu
Journal: Reprod Biol Endocrinol
PubMed ID: 34266426
Doi: 10.1186/s12958-021-00796-z
Latent tuberculosis co-infection is associated with heightened levels of humoral, cytokine and acute phase responses in seropositive SARS-CoV-2 infection
Authors: Anuradha Rajamanickam, Nathella Pavan Kumar, Chandrasekaran Padmapriyadarsini, Arul Nancy, Nandhini Selvaraj, Kushiyasri Karunanithi, Saravanan Munisankar, Shrinivasa Bm, Rachel Mariam Renji, T C Ambu, Vijayalakshmi Venkataramani, Subash Babu
Journal: J Infect
PubMed ID: 34329676
Doi: 10.1016/j.jinf.2021.07.029
Structure of a mammalian sperm cation channel complex
Authors: Shiyi Lin, Meng Ke, Yuqi Zhang, Zhen Yan, Jianping Wu
Journal: Nature
PubMed ID: 34225353
Doi: 10.1038/s41586-021-03742-6
Epitope-Paratope Interaction of a Neutralizing Human Anti-Hepatitis B Virus PreS1 Antibody That Recognizes the Receptor-Binding Motif
Authors: Jisu Hong, Youngjin Choi, Yoonjoo Choi, Jiwoo Lee, Hyo Jeong Hong
Journal: Vaccines (Basel)
PubMed ID: 34358170
Doi: 10.3390/vaccines9070754
Adult-born proopiomelanocortin neurons derived from Rax-expressing precursors mitigate the metabolic effects of congenital hypothalamic proopiomelanocortin deficiency
Authors: Gábor Wittmann, Malcolm J Low, Ronald M Lechan
Journal: Mol Metab
PubMed ID: 34329773
Doi: 10.1016/j.molmet.2021.101312
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Cytosolic GDH1 degradation restricts protein synthesis to sustain tumor cell survival following amino acid deprivation
Authors: Jialiang Shao, Tiezhu Shi, Hua Yu, Yufeng Ding, Liping Li, Xiang Wang, Xiongjun Wang
Journal: EMBO J
PubMed ID: 34269483
Doi: 10.15252/embj.2020107480
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Clinical utility of a serum biomarker panel in distinguishing prostate cancer from benign prostate hyperplasia
Authors: Michael A Kiebish, Poornima Tekumalla, Shobha Ravipaty, Albert Dobi, Shiv Srivastava, Wenfang Wu, Saurabh Patil, Tracey Friss, Allison Klotz, Alagarsamy Srinivasan, Jennifer Cullen, Inger L Rosner, Amina Ali, Sandra Laszlo, Michele Petrovic, Neil Fleshner, Jeonifer Garren, Greg Miller, Nischal Mahaveer Chand, Leonardo O Rodrigues, Elder Granger, Mark D Kellogg, Shen Luan, Eleftherios Diamandis, Viatcheslav R Akmaev, Rangaprasad Sarangarajan, Chas Bountra, Stephen J Freedland, David G McLeod, Niven R Narain
Journal: Sci Rep
PubMed ID: 34302010
Doi: 10.1038/s41598-021-94438-4
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Hepta-Histidine Inhibits Tau Aggregation
Authors: Kanoh Kondo, Teikichi Ikura, Hikari Tanaka, Kyota Fujita, Sumire Takayama, Yuki Yoshioka, Kazuhiko Tagawa, Hidenori Homma, Su Liu, Ryosuke Kawasaki, Yong Huang, Nobutoshi Ito, Shin-Ichi Tate, Hitoshi Okazawa
Journal: ACS Chem Neurosci
PubMed ID: 34319089
Doi: 10.1021/acschemneuro.1c00164
Products & Services: Peptide Library Services   
The importance of vitellogenin receptors in the oviposition of the pond wolf spider, Pardosa pseudoannulata
Authors: Zhi-Ming Yang, Tian-Yu Lu, Yong Wu, Na Yu, Guang-Ming Xu, Qian-Qian Han, Ze-Wen Liu
Journal: Insect Sci
PubMed ID: 34237799
Doi: 10.1111/1744-7917.12933
Products & Services: PCR and Cloning   
High density lipoproteins mediate in vivo protection against staphylococcal phenol-soluble modulins
Authors: Josefien W Hommes, Rachel M Kratofil, Sigrid Wahlen, Carla J C de Haas, Reeni B Hildebrand, G Kees Hovingh, Micheal Otto, Miranda van Eck, Menno Hoekstra, Suzanne J A Korporaal, Bas G J Surewaard
Journal: Sci Rep
PubMed ID: 34321507
Doi: 10.1038/s41598-021-94651-1
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An octopamine receptor confers selective toxicity of amitraz on honeybees and mites
Authors: Lei Guo, Xin-Yu Fan, Xiaomu Qiao, Craig Montell, Jia Huang
Journal: Elife
PubMed ID: 34263722
Doi: 10.7554/eLife.68268
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Can commercial automated immunoassays be utilized to predict neutralizing antibodies after SARS-CoV-2 infection? A comparative study between three different assays
Authors: Ahmed Ismail, Farah M Shurrab, Hadeel T Al-Jighefee, Duaa W Al-Sadeq, Hamda Qotba, Ibrahim Abdu Al-Shaar, Hadi M Yassine, Laith J Abu-Raddad, Gheyath K Nasrallah
Journal: Front Biosci (Landmark Ed)
PubMed ID: 34340267
Doi: 10.52586/4934
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Gadolinium-labeled affibody-XTEN recombinant vector for detection of HER2+ lesions of ovarian cancer lung metastasis using quantitative MRI
Authors: Alireza Nomani, Geng Li, Siavash Yousefi, Shawn Wu, Obeid M Malekshah, Shahryar K Nikkhoi, Mehrdad Pourfathi, Rahim Rizi, Arash Hatefi
Journal: J Control Release
PubMed ID: 34284047
Doi: 10.1016/j.jconrel.2021.07.022
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Assays for studying normal suppressive ERAD-associated retrotranslocation pathways in yeast
Authors: Satarupa Bhaduri, Sonya E Neal
Journal: STAR Protoc
PubMed ID: 34278330
Doi: 10.1016/j.xpro.2021.100640
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Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry
Authors: Alessandra Luchini, Samantha Micciulla, Giacomo Corucci, Krishna Chaithanya Batchu, Andreas Santamaria, Valerie Laux, Tamim Darwish, Robert A Russell, Michel Thepaut, Isabelle Bally, Franck Fieschi, Giovanna Fragneto
Journal: Sci Rep
PubMed ID: 34290262
Doi: 10.1038/s41598-021-93996-x
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AstraZeneca (AZD1222) Covid 19 vaccine-associated adverse drug event: a case report
Authors: Capassoni Marco, Ketabchi Sheyda, Cassisa Angelo, Caramelli Riccardo, Molinu Antonietta Anna, Galluccio Felice, Guiducci Serena
Journal: J Med Virol
PubMed ID: 34214206
Doi: 10.1002/jmv.27175
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miR-29c-3p regulates TET2 expression and inhibits autophagy process in Parkinson's disease models
Authors: Ruili Wang, Jie Yao, Fuhua Gong, Songsheng Chen, Ya He, Chunting Hu, Chen Li
Journal: Genes Cells
PubMed ID: 34086379
Doi: 10.1111/gtc.12877
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Development of a Bioluminescent Human Osteosarcoma Model in Humanized NSG Mice: A Pilot Study
Authors: Yunmi Ko, Yeon Ho Jeong, Jin-Hee Seo, Jun Ah Lee
Journal: In Vivo
PubMed ID: 34182491
Doi: 10.21873/invivo.12485
Loss of MIC60 Aggravates Neuronal Death by Inducing Mitochondrial Dysfunction in a Rat Model of Intracerebral Hemorrhage
Authors: Ruming Deng, Wenjie Wang, Xiang Xu, Jiasheng Ding, Jiahe Wang, Siyuan Yang, Haiying Li, Haitao Shen, Xiang Li, Gang Chen
Journal: Mol Neurobiol
PubMed ID: 34232477
Doi: 10.1007/s12035-021-02468-w
Products & Services: Gene Synthesis   
PTEN regulates adipose progenitor cell growth, differentiation, and replicative aging
Authors: Anna S Kirstein, Stephanie Kehr, Michèle Nebe, Martha Hanschkow, Lisa A G Barth, Judith Lorenz, Melanie Penke, Jana Breitfeld, Diana Le Duc, Kathrin Landgraf, Antje Körner, Peter Kovacs, Peter F Stadler, Wieland Kiess, Antje Garten
Journal: J Biol Chem
PubMed ID: 34273354
Doi: 10.1016/j.jbc.2021.100968
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Longitudinal variation in SARS-CoV-2 antibody levels and emergence of viral variants: implications for the ability of serological assays to predict immunity
Authors: Frauke Muecksch, Helen Wise, Kate Templeton, Becky Batchelor, Maria Squires, Kirsty McCance, Lisa Jarvis, Kristen Malloy, Elizabeth Furrie, Claire Richardson, Jacqueline MacGuire, Ian Godber, Alana Burns, Sally Mavin, Fengwen Zhang, Fabian Schmidt, Paul Bieniasz, Sara Jenks, Theodora Hatziioannou
Journal: medrxiv
PubMed ID: 34268524
Doi: 10.1101/2021.07.02.21259939
Single-chain Fragment variable antibody targeting cholecystokinin-B receptor for pain reduction
Authors: K N Westlund, M A Montera, A E Goins, S R A Alles, M Afaghpour-Becklund, R Bartel, R Durvasula, A Kunamneni
Journal: Neurobiol Pain
PubMed ID: 34458647
Doi: 10.1016/j.ynpai.2021.100067
Products & Services: Monoclonal Antibody Services   
The RNase MCPIP3 promotes skin inflammation by orchestrating myeloid cytokine response
Authors: Bo Liu, Jiancheng Huang, Amina Ashraf, Oindrila Rahaman, Jing Lou, Ling Wang, Peiliang Cai, Jinping Wen, Shoaib Anwaar, Xiaoli Liu, Hai Ni, Dipyaman Ganguly, Jijun Zhao, Cliff Y Yang
Journal: Nat Commun
PubMed ID: 34215755
Doi: 10.1038/s41467-021-24352-w
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Genome-wide identification of candidate aquaporins involved in water accumulation of pomegranate outer seed coat
Authors: Jianjian Liu, Gaihua Qin, Chunyan Liu, Xiuli Liu, Jie Zhou, Jiyu Li, Bingxin Lu, Jianrong Zhao
Journal: PeerJ
PubMed ID: 34316414
Doi: 10.7717/peerj.11810
Products & Services: Protein Tools   
Screening New Xylanase Biocatalysts from the Mangrove Soil Diversity
Authors: Corinne Ivaldi, Mariane Daou, Laurent Vallon, Alexandra Bisotto, Mireille Haon, Sona Garajova, Emmanuel Bertrand, Craig B Faulds, Giuliano Sciara, Adrien Jacotot, Cyril Marchand, Mylène Hugoni, Harivony Rakotoarivonina, Marie-Noëlle Rosso, Caroline Rémond, Patricia Luis, Eric Record
Journal: Microorganisms
PubMed ID: 34361919
Doi: 10.3390/microorganisms9071484
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Tobacco BY2 cells expressing recombinant cardosin B as an alternative for production of active milk clotting enzymes
Authors: André Folgado, Rita Abranches
Journal: Sci Rep
PubMed ID: 34262119
Doi: 10.1038/s41598-021-93882-6
Products & Services: Mammalian Expression   
Heat-dependent opening of TRPV1 in the presence of capsaicin
Authors: Do Hoon Kwon, Feng Zhang, Yang Suo, Jonathan Bouvette, Mario J Borgnia, Seok-Yong Lee
Journal: Nat Struct Mol Biol
PubMed ID: 34239123
Doi: 10.1038/s41594-021-00616-3
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The upstream 5' splice site remains associated to the transcription machinery during intron synthesis
Authors: Yodfat Leader, Galit Lev Maor, Matan Sorek, Ronna Shayevitch, Maram Hussein, Ofir Hameiri, Luna Tammer, Jonathan Zonszain, Ifat Keydar, Dror Hollander, Eran Meshorer, Gil Ast
Journal: Nat Commun
PubMed ID: 34315864
Doi: 10.1038/s41467-021-24774-6
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Low neutralizing antibody responses in WM, CLL and NHL patients after the first dose of the BNT162b2 and AZD1222 vaccine
Authors: Maria Gavriatopoulou, Evangelos Terpos, Efstathios Kastritis, Alexandros Briasoulis, Sentiljana Gumeni, Ioannis Ntanasis-Stathopoulos, Aimilia D Sklirou, Panagiotis Malandrakis, Evangelos Eleutherakis-Papaiakovou, Magdalini Migkou, Ioannis P Trougakos, Meletios A Dimopoulos
Journal: Clin Exp Med
PubMed ID: 34283338
Doi: 10.1007/s10238-021-00746-4
Overexpression of Douglas-Fir () in Induces Embryonic Programs and Embryo-like Structures in the Mutant but Not in Wild Type Plants
Authors: Mariana A Vetrici, Dmytro P Yevtushenko, Santosh Misra
Journal: Plants (Basel)
PubMed ID: 34451571
Doi: 10.3390/plants10081526
Integrated workflow for urinary prostate specific antigen N-glycosylation analysis using sdAb partitioning and downstream capillary electrophoresis separation
Authors: Balazs Reider, Eszter Gacsi, Hajnalka Jankovics, Ferenc Vonderviszt, Tibor Szarvas, Andras Guttman, Gabor Jarvas
Journal: Anal Chim Acta
PubMed ID: 34625256
Doi: 10.1016/j.aca.2021.338892
Products & Services: PCR Cloning and Subcloning   
Impact of temperature on the affinity of SARS-CoV-2 Spike for ACE2
Authors: Jérémie Prévost, Jonathan Richard, Romain Gasser, Shilei Ding, Clément Fage, Sai Priya Anand, Damien Adam, Natasha Gupta Vergara, Alexandra Tauzin, Mehdi Benlarbi, Shang Yu Gong, Guillaume Goyette, Anik Privé, Sandrine Moreira, Hugues Charest, Michel Roger, Walther Mothes, Marzena Pazgier, Emmanuelle Brochiero, Guy Boivin, Cameron F Abrams, Arne Schön, Andrés Finzi
Journal: biorxiv
PubMed ID: 34268505
Doi: 10.1101/2021.07.09.451812
Products & Services: Mutant Libraries   
Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration
Authors: Hao Huang, Alexander Gont, Lynn Kee, Ruben Dries, Kathrin Pfeifer, Bandana Sharma, David N Debruyne, Matthew Harlow, Satyaki Sengupta, Jikui Guan, Caleb M Yeung, Wenchao Wang, Bengt Hallberg, Ruth H Palmer, Meredith S Irwin, Rani E George
Journal: Cell Rep
PubMed ID: 34260934
Doi: 10.1016/j.celrep.2021.109363
Products & Services: Gene Synthesis   
LncRNA HOXA11-AS promotes cell growth by sponging miR-24-3p to regulate JPT1 in prostate cancer
Authors: Y Cheng, H-Y Xiong, Y-M Li, H-R Zuo, Y Liu, G-L Liao
Journal: Eur Rev Med Pharmacol Sci
PubMed ID: 34337714
Doi: 10.26355/eurrev_202107_26377
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Association of total and neutralizing SARS-CoV-2 spike -receptor binding domain antibodies with epidemiological and clinical characteristics after immunization with the 1 and 2 doses of the BNT162b2 vaccine
Authors: Athanasios Michos, Elizabeth-Barbara Tatsi, Filippos Filippatos, Charilaos Dellis, Dimitra Koukou, Vasiliki Efthymiou, Evangelia Kastrinelli, Aimilia Mantzou, Vasiliki Syriopoulou
Journal: Vaccine
PubMed ID: 34400017
Doi: 10.1016/j.vaccine.2021.07.067
An increase in VGF expression through a rapid, transcription-independent, autofeedback mechanism improves cognitive function
Authors: Wei-Jye Lin, Yan Zhao, Zhe Li, Shuyu Zheng, Jin-Lin Zou, Noël A Warren, Purva Bali, Jingru Wu, Mengdan Xing, Cheng Jiang, Yamei Tang, Stephen R Salton, Xiaojing Ye
Journal: Transl Psychiatry
PubMed ID: 34238925
Doi: 10.1038/s41398-021-01489-2
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Activation of Adenosine A Receptor in Ischemic Stroke: Neuroprotection by Tetrahydroxy Stilbene Glycoside as an Agonist
Authors: Lingyu Ruan, Guanghui Li, Wenlong Zhao, Huihui Meng, Qi Zheng, Junsong Wang
Journal: Antioxidants (Basel)
PubMed ID: 34356346
Doi: 10.3390/antiox10071112
Products & Services: Plasmid DNA Preparation   
Differential Modulation of Heat-Inducible Genes Across Diverse Genotypes and Molecular Cloning of a sHSP From Pearl Millet [ (L) R Br]
Authors: S Mukesh Sankar, C Tara Satyavathi, Sharmistha Barthakur, Sumer Pal Singh, C Bharadwaj, S L Soumya
Journal: Front Plant Sci
PubMed ID: 34335644
Doi: 10.3389/fpls.2021.659893
Products & Services: Molecular Biology Tools   
Introduction of the Carotenoid Biosynthesis α-Branch Into sp PCC 6803 for Lutein Production
Authors: Martin Lehmann, Evgenia Vamvaka, Alejandro Torrado, Peter Jahns, Marcel Dann, Lea Rosenhammer, Amel Aziba, Dario Leister, Thilo Rühle
Journal: Front Plant Sci
PubMed ID: 34295345
Doi: 10.3389/fpls.2021.699424
Products & Services: Codon Optimization   
The B-cell Receptor Autoantigen LRPAP1 Can Replace Variable Antibody Regions to Target Mantle Cell Lymphoma Cells
Authors: Moritz Bewarder, Maximilian Kiefer, Helene Will, Kathrin Olesch, Clara Moelle, Stephan Stilgenbauer, Konstantinos Christofyllakis, Dominic Kaddu-Mulindwa, Joerg Thomas Bittenbring, Natalie Fadle, Evi Regitz, Lea Kaschek, Markus Hoth, Frank Neumann, Klaus-Dieter Preuss, Michael Pfreundschuh, Lorenz Thurner
Journal: HemaSphere
PubMed ID: 34263144
Doi: 10.1097/HS9.0000000000000620
Products & Services: Peptide Synthesis   
Persistent symptoms in adult patients one year after COVID-19: a prospective cohort study
Authors: Jessica Seeßle, Tim Waterboer, Theresa Hippchen, Julia Simon, Marietta Kirchner, Adeline Lim, Barbara Müller, Uta Merle
Journal: Clin Infect Dis
PubMed ID: 34223884
Doi: 10.1093/cid/ciab611
Products & Services: PCR and Cloning   
Antibody Response After Initial Vaccination for SARS-CoV-2 in Patients With Amyloidosis
Authors: Efstathios Kastritis, Evangelos Terpos, Aimilia Sklirou, Foteini Theodorakakou, Despina Fotiou, Eleni-Dimitra Papanagnou, Tina Bagratuni, Nikolaos Kanellias, Maria Gavriatopoulou, Ioannis P Trougakos, Meletios A Dimopoulos
Journal: HemaSphere
PubMed ID: 34278231
Doi: 10.1097/HS9.0000000000000614
Human Hyaluronidase PH20 Potentiates the Antitumor Activities of Mesothelin-Specific CAR-T Cells Against Gastric Cancer
Authors: Ruocong Zhao, Yuanbin Cui, Yongfang Zheng, Shanglin Li, Jiang Lv, Qiting Wu, Youguo Long, Suna Wang, Yao Yao, Wei Wei, Jie Yang, Bin-Chao Wang, Zhenfeng Zhang, Hui Zeng, Yangqiu Li, Peng Li
Journal: Front Immunol
PubMed ID: 34326835
Doi: 10.3389/fimmu.2021.660488
Products & Services: Mammalian Expression   
High Prevalence of Anti-PF4 Antibodies Following ChAdOx1 nCov-19 (AZD1222) Vaccination Even in the Absence of Thrombotic Events
Authors: Evangelos Terpos, Marianna Politou, Ioannis Ntanasis-Stathopoulos, Vangelis Karalis, Efrosyni Merkouri, Despina Fotiou, Maria Gavriatopoulou, Panagiotis Malandrakis, Efstathios Kastritis, Ioannis P Trougakos, Meletios A Dimopoulos
Journal: Vaccines (Basel)
PubMed ID: 34358129
Doi: 10.3390/vaccines9070712
Surveillance of Borrelia miyamotoi-carrying ticks and genomic analysis of isolates in Inner Mongolia, China
Authors: Kozue Sato, Dan Liu, Yunhong Cui, Xuhong Yin, Lihua Zhang, Hong Li, Tingfu Wang, Rongxin Liu, Lijing Wu, Saixia Lu, Ting Gao, Zitong Zhang, Minzhi Cao, Guodong Wang, Chunpu Li, Dacheng Yan, Norio Ohashi, Shuji Ando, Hiroki Kawabata
Journal: Parasit Vectors
PubMed ID: 34274015
Doi: 10.1186/s13071-021-04809-z
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