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Decline in neutralising antibody responses, but sustained T-cell immunity, in COVID-19 patients at 7 months post-infection
Authors: Jun Chen, Xiaomin Liu, Xinyu Zhang, Yixiao Lin, Danping Liu, Jingna Xun, Zhenyan Wang, Ling Gu, Qian Li, Dan Yin, Junyang Yang, Hongzhou Lu
Journal: Clin Transl Immunology
PubMed ID: 34336207
Doi: 10.1002/cti2.1319
Products & Services: Molecular Biology Reagents   
Polymersomes Decorated with the SARS-CoV-2 Spike Protein Receptor-Binding Domain Elicit Robust Humoral and Cellular Immunity
Authors: Lisa R Volpatti, Rachel P Wallace, Shijie Cao, Michal M Raczy, Ruyi Wang, Laura T Gray, Aaron T Alpar, Priscilla S Briquez, Nikolaos Mitrousis, Tiffany M Marchell, Maria Stella Sasso, Mindy Nguyen, Aslan Mansurov, Erica Budina, Ani Solanki, Elyse A Watkins, Mathew R Schnorenberg, Andrew C Tremain, Joseph W Reda, Vlad Nicolaescu, Kevin Furlong, Steve Dvorkin, Shann S Yu, Balaji Manicassamy, James L LaBelle, Matthew V Tirrell, Glenn Randall, Marcin Kwissa, Melody A Swartz, Jeffrey A Hubbell
Journal: ACS Cent Sci
PubMed ID: 34466656
Doi: 10.1021/acscentsci.1c00596
Products & Services: Molecular Biology Reagents   
Poor humoral and T-cell response to two-dose SARS-CoV-2 messenger RNA vaccine BNT162b2 in cardiothoracic transplant recipients
Authors: René Schramm, Angelika Costard-Jäckle, Rasmus Rivinius, Bastian Fischer, Benjamin Müller, Udo Boeken, Assad Haneya, Zdenek Provaznik, Cornelius Knabbe, Jan Gummert
Journal: Clin Res Cardiol
PubMed ID: 34241676
Doi: 10.1007/s00392-021-01880-5
Products & Services: Immunoassay Development Services   
A highly efficient identification of mutants generated by CRISPR/Cas9 using the non‑functional DsRed assisted selection in Aspergillus oryzae
Authors: Yuzhen Li, Huanxin Zhang, Junxia Fan, Ziming Chen, Tianming Chen, Bin Zeng, Zhe Zhang
Journal: World J Microbiol Biotechnol
PubMed ID: 34240255
Doi: 10.1007/s11274-021-03100-8
Products & Services: Gene Synthesis   
Rapid and cost-effective process based on insect larvae for scale-up production of SARS-COV-2 spike protein for serological COVID-19 testing
Authors: Ignacio Smith, Gregorio Juan Mc Callum, Adriana Victoria Sabljic, Juan Ignacio Marfia, Silvina Sonia Bombicino, Aldana Trabucchi, Ruben Francisco Iacono, Joaquín Manuel Birenbaum, Susana Claudia Vazquez, Juan Mauricio Minoia, Osvaldo Cascone, María Gabriela López, Oscar Taboga, Alexandra Marisa Targovnik, Federico Javier Wolman, Matías Fingermann, Leonardo Gabriel Alonso, Silvina Noemí Valdez, María Victoria Miranda
Journal: Biotechnol Bioeng
PubMed ID: 34264519
Doi: 10.1002/bit.27889
Products & Services: DNA Sequencing   
Absence of SARS-CoV-2 Antibodies in Natural Environment Exposure in Sheep in Close Contact with Humans
Authors: Sergio Villanueva-Saz, Jacobo Giner, Antonio Fernández, Delia Lacasta, Aurora Ortín, Juan José Ramos, Luis Miguel Ferrer, Marta Ruiz de Arcaute, Ana Pilar Tobajas, María Dolores Pérez, Maite Verde, Diana Marteles, Ramón Hurtado-Guerrero, Julián Pardo, Llipsy Santiago, Andrés Manuel González-Ramírez, Javier Macías-León, Ana García-García, Víctor Taleb, Erandi Lira-Navarrete, José Ramón Paño-Pardo, Héctor Ruíz
Journal: Animals (Basel)
PubMed ID: 34359111
Doi: 10.3390/ani11071984
Products & Services: DNA Sequencing   
The Knockdown of Inhibits the Papillary Thyroid Cancer Development by Promoting Ferroptosis Upon Downregulation
Authors: Lidong Wang, Ying Zhang, Jiapeng Yang, Lei Liu, Baiyu Yao, Zhong Tian, Jingni He
Journal: DNA Cell Biol
PubMed ID: 34283663
Doi: 10.1089/dna.2021.0216
Products & Services: DNA Sequencing   
m(6)A Modification of lncRNA NEAT1 Regulates Chronic Myelocytic Leukemia Progression miR-766-5p/CDKN1A Axis
Authors: Fang-Yi Yao, Cui Zhao, Fang-Min Zhong, Ting-Yu Qin, Fang Wen, Mei-Yong Li, Jing Liu, Bo Huang, Xiao-Zhong Wang
Journal: Front Oncol
PubMed ID: 34354942
Doi: 10.3389/fonc.2021.679634
Products & Services: DNA Sequencing   
Structure of respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation
Authors: Piotr Kolata, Rouslan G Efremov
Journal: Elife
PubMed ID: 34308841
Doi: 10.7554/eLife.68710
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Depolymerization of biorefinery lignin by improved laccases of the white-rot fungus Obba rivulosa
Authors: Janne Wallenius, Jussi Kontro, Christina Lyra, Jaana Kuuskeri, Xing Wan, Mika A Kähkönen, Irshad Baig, Paul C J Kamer, Jussi Sipilä, Miia R Mäkelä, Paula Nousiainen, Kristiina Hildén
Journal: Microb Biotechnol
PubMed ID: 34310858
Doi: 10.1111/1751-7915.13896
Products & Services: Custom Vector Construction   
Psoralen inhibits the inflammatory response and mucus production in allergic rhinitis by inhibiting the activator protein 1 pathway and the downstream expression of cystatin‑SN
Authors: Wenying Gao, Zhenglong Jin, Yanxia Zheng, Youjia Xu
Journal: Mol Med Rep
PubMed ID: 34278468
Doi: 10.3892/mmr.2021.12291
Products & Services: Custom DNA/RNA Oligos   
Multiple neuronal networks coordinate mechanosensory behavior
Authors: Krishna N Badhiwala, Abby S Primack, Celina E Juliano, Jacob T Robinson
Journal: Elife
PubMed ID: 34328079
Doi: 10.7554/eLife.64108
Products & Services: Codon Optimization   
Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture
Authors: Julia Nörpel, Simone Cavadini, Andreas D Schenk, Alexandra Graff-Meyer, Daniel Hess, Jan Seebacher, Jeffrey A Chao, Varun Bhaskar
Journal: PLoS Biol
PubMed ID: 34297726
Doi: 10.1371/journal.pbio.3001344
Products & Services: Codon Optimization   
Observing reorientation dynamics with Time-Resolved fluorescence and molecular dynamics in varying periodic boundary conditions
Authors: Gouri S Jas, Ed W Childs, C Russell Middaugh, Krzysztof Kuczera
Journal: J Biomol Struct Dyn
PubMed ID: 34308794
Doi: 10.1080/07391102.2021.1947894
Products & Services: Catalog Peptides   
Screening of potent neutralizing antibodies against SARS-CoV-2 using convalescent patients-derived phage-display libraries
Authors: Yongbing Pan, Jianhui Du, Jia Liu, Hai Wu, Fang Gui, Nan Zhang, Xiaojie Deng, Gang Song, Yufeng Li, Jia Lu, Xiaoli Wu, ShanShan Zhan, Zhaofei Jing, Jiong Wang, Yimin Yang, Jianbang Liu, Ying Chen, Qin Chen, Huanyu Zhang, Hengrui Hu, Kai Duan, Manli Wang, Qisheng Wang, Xiaoming Yang
Journal: Cell Discov
PubMed ID: 34315862
Doi: 10.1038/s41421-021-00295-w
Products & Services: Catalog Antibody   
Multiple regulatory intrinsically disordered motifs control FOXO4 transcription factor binding and function
Authors: Benjamin Bourgeois, Tianshu Gui, Diana Hoogeboom, Henry G Hocking, Gesa Richter, Emil Spreitzer, Martin Viertler, Klaus Richter, Tobias Madl, Boudewijn M T Burgering
Journal: Cell Rep
PubMed ID: 34320339
Doi: 10.1016/j.celrep.2021.109446
Products & Services: Gene Synthesis   
Protocol for interfering peptide injection into adult mouse hippocampus and spatial memory testing
Authors: Shanshan Cheng, Yuqian Shen, Zi Chao Zhang, Junhai Han
Journal: STAR Protoc
PubMed ID: 34337444
Doi: 10.1016/j.xpro.2021.100679
Products & Services: Peptide Synthesis   
A novel larval diet interacts with nutritional stress to modify juvenile behaviors and glucocorticoid responses
Authors: Cristina C Ledón-Rettig, Sarah R Lagon
Journal: Ecol Evol
PubMed ID: 34429887
Doi: 10.1002/ece3.7860
Structural Investigation of Orf Virus Bcl-2 Homolog ORFV125 Interactions with BH3-Motifs from BH3-Only Proteins Puma and Hrk
Authors: Chathura D Suraweera , Mark G Hinds , Marc Kvansakul
Journal: Viruses
PubMed ID: 34372579
Doi: 10.3390/v13071374
Products & Services: Gene Synthesis   
Chromosome-level genome of Himalayan yew provides insights into the origin and evolution of the paclitaxel biosynthetic pathway
Authors: Jian Cheng , Xiao Wang, Xiaonan Liu , Xiaoxi Zhu , Zihe Li , Huanyu Chu , Qian Wang , QianQian Lou , Bijun Cai , Yiqun Yang , Xiaoyun Lu , Kai Peng , Dingyu Liu , Yuwan Liu , Lina Lu , Huan Liu , Ting Yang , Qijin Ge , Chengcheng Shi , Guichun Liu , Zhiwei Dong , Xun Xu , Wen Wang , Huifeng Jiang , Yanhe Ma
Journal: Mol Plant
PubMed ID: 33951484
Doi: 10.1016/j.molp.2021.04.015
Products & Services: Gene Synthesis   
Immunomodulatory, trypanocide, and antioxidant properties of essential oil fractions of Lippia alba (Verbenaceae)
Authors: Wendy Lorena Quintero, Erika Marcela Moreno, Sandra Milena Leal Pinto, Sandra Milena Sanabria, Elena Stashenko, Liliana Torcoroma García
Journal: BMC Complement Med Ther
PubMed ID: 34215249
Doi: 10.1186/s12906-021-03347-6
Products & Services: PCR Cloning and Subcloning   
Evidence for a chromosome origin unwinding system broadly conserved in bacteria
Authors: Simone Pelliciari, Mei-Jing Dong, Feng Gao, Heath Murray
Journal: Nucleic Acids Res
PubMed ID: 34197592
Doi: 10.1093/nar/gkab560
Products & Services: Gene Synthesis   
Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine
Authors: Kelly L Hawley, Jairo M Montezuma-Rusca, Kristina N Delgado, Navreeta Singh, Vladimir N Uversky, Melissa J Caimano, Justin D Radolf, Amit Luthra
Journal: J Bacteriol
PubMed ID: 33972353
Doi: 10.1128/JB.00082-21
Products & Services: Codon Optimization   
Genetic Code Expansion: A Brief History and Perspective
Authors: Mia A Shandell, Zhongping Tan, Virginia W Cornish
Journal: Biochemistry
PubMed ID: 34196546
Doi: 10.1021/acs.biochem.1c00286
Products & Services: Molecular Biology Tools   
Signal-transducing adaptor protein-2 has a nonredundant role for IL-33-triggered mast cell activation
Authors: Jun-Ichi Kashiwakura, Nao Koizumi, Kodai Saitoh, Kota Kagohashi, Yuto Sasaki, Fuki Kobayashi, Shoya Kawahara, Yukie Yamauchi, Yuichi Kitai, Ryuta Muromoto, Kenji Oritani, Tadashi Matsuda
Journal: Biochem Biophys Res Commun
PubMed ID: 34358967
Doi: 10.1016/j.bbrc.2021.07.098
Optimizing the Expression and Solubilization of an E coli-Produced Leukemia Inhibitory Factor for Anti-LIF Antibody Production and Use Thereof for Contraception in Mice
Authors: Nahid Mehri, Abbas Jamshidizad, Zahra Ghanei, Ali-Asghar Karkhane, Mehdi Shamsara
Journal: Mol Biotechnol
PubMed ID: 34272681
Doi: 10.1007/s12033-021-00369-w
Products & Services: Codon Optimization   
Characterization of gH/gL/pUL128-131 pentameric complex, gH/gL/gO trimeric complex, gB and gM/gN glycoproteins in a human cytomegalovirus using automated capillary western blots
Authors: Richard R Rustandi, John W Loughney, Liang Shang, Shiyi Wang, Cindy J Pauley, Sianny Christanti, Adam Kristopeit, Timothy D Culp
Journal: Vaccine
PubMed ID: 34229890
Doi: 10.1016/j.vaccine.2021.06.033
Products & Services: Mammalian Expression   
Altered chromatin architecture and gene expression during polyploidization and domestication of soybean
Authors: Longfei Wang, Guanghong Jia, Xinyu Jiang, Shuai Cao, Z Jeffrey Chen, Qingxin Song
Journal: Plant Cell
PubMed ID: 33730165
Doi: 10.1093/plcell/koab081
The Neurotrophin Receptor TrkC as a Novel Molecular Target of the Antineuroblastoma Action of Valproic Acid
Authors: Simona Dedoni, Luisa Marras, Maria C Olianas, Angela Ingianni, Pierluigi Onali
Journal: Int J Mol Sci
PubMed ID: 34360553
Doi: 10.3390/ijms22157790
Products & Services: Mammalian Expression   
Cellular 5'-3' mRNA Exoribonuclease XRN1 Inhibits Interferon Beta Activation and Facilitates Influenza A Virus Replication
Authors: Yen-Chin Liu, Bobo Wing-Yee Mok, Pui Wang, Rei-Lin Kuo, Honglin Chen, Shin-Ru Shih
Journal: MBio
PubMed ID: 34311580
Doi: 10.1128/mBio.00945-21
Products & Services: Plasmid DNA Preparation   
Functional expression of the eukaryotic proton pump rhodopsin OmR2 in Escherichia coli and its photochemical characterization
Authors: Masuzu Kikuchi, Keiichi Kojima, Shin Nakao, Susumu Yoshizawa, Shiho Kawanishi, Atsushi Shibukawa, Takashi Kikukawa, Yuki Sudo
Journal: Sci Rep
PubMed ID: 34285294
Doi: 10.1038/s41598-021-94181-w
Products & Services: Mammalian Expression   
CTP and coordinate ParB partition complex dynamics and ParA-ATPase activation for ParABS-mediated DNA partitioning
Authors: James A Taylor, Yeonee Seol, Jagat Budhathoki, Keir C Neuman, Kiyoshi Mizuuchi
Journal: Elife
PubMed ID: 34286695
Doi: 10.7554/eLife.65651
Products & Services: PCR Cloning and Subcloning   
The circadian clock gates adult emergence by controlling the timecourse of metamorphosis
Authors: Brandon Mark, Liliana Bustos-González, Guadalupe Cascallares, Felipe Conejera, John Ewer
Journal: Proc Natl Acad Sci U S A
PubMed ID: 34183412
Doi: 10.1073/pnas.2023249118
Reconstitution of human CMG helicase ubiquitylation by CUL2LRR1 and multiple E2 enzymes
Authors: Thanh Thi Le, Johanna Ainsworth, Cristian Polo Rivera, Thomas Macartney, Karim P M Labib
Journal: Biochem J
PubMed ID: 34195792
Doi: 10.1042/BCJ20210315
Products & Services: Mammalian Expression   
KDM1A Promotes Immunosuppression in Hepatocellular Carcinoma by Regulating PD-L1 through Demethylating MEF2D
Authors: Yonglan Wang, Kun Cao
Journal: J Immunol Res
PubMed ID: 34307695
Doi: 10.1155/2021/9965099
Structural and immunological characterization of an epitope within the PAN motif of ectodomain I in apical membrane antigen 1 for vaccine development
Authors: Amarin Rittipornlertrak, Boondarika Nambooppha, Anucha Muenthaisong, Veerasak Punyapornwithaya, Saruda Tiwananthagorn, Yang-Tsung Chung, Bumduuren Tuvshintulga, Thillaiampalam Sivakumar, Naoaki Yokoyama, Nattawooti Sthitmatee
Journal: PeerJ
PubMed ID: 34316404
Doi: 10.7717/peerj.11765
Products & Services: Catalog Peptides   
Identification of Three Clf-Sdr Subfamily Proteins in , and Comparative Genomics Analysis of a Locus Encoding CWA Proteins in Species
Authors: Zhewei Sun, Xueya Zhang, Danying Zhou, Kexin Zhou, Qiaoling Li, Hailong Lin, Wei Lu, Hongmao Liu, Junwan Lu, Xi Lin, Kewei Li, Teng Xu, Mei Zhu, Qiyu Bao, Hailin Zhang
Journal: Front Microbiol
PubMed ID: 34394031
Doi: 10.3389/fmicb.2021.691087
Products & Services: Catalog Peptides   
The enhanced phosphorus use efficiency in phosphate-deficient and mycorrhiza-inoculated barley seedlings involves activation of different sets of PHT1 transporters in roots
Authors: Rajat Srivastava, Parul Sirohi, Harsh Chauhan, Rahul Kumar
Journal: Planta
PubMed ID: 34312721
Doi: 10.1007/s00425-021-03687-0
Products & Services: Protein Tools   
Global Profiling of Phosphorylation Reveals the Barley Roots Response to Phosphorus Starvation and Resupply
Authors: Zengke Ma, Juncheng Wang, Chengdao Li, Panrong Ren, Lirong Yao, Baochun Li, Yaxiong Meng, Xiaole Ma, Erjing Si, Ke Yang, Xunwu Shang, Huajun Wang
Journal: Front Plant Sci
PubMed ID: 34335649
Doi: 10.3389/fpls.2021.676432
Products & Services: Protein Tools   
AP39 ameliorates high fat diet-induced liver injury in young rats via alleviation of oxidative stress and mitochondrial impairment
Authors: Yue Yu, Shu-Ming Ye, De-Yun Liu, Li-Qi Yang
Journal: Exp Anim
PubMed ID: 34305077
Doi: 10.1538/expanim.21-0056
Products & Services: Custom DNA/RNA Oligos   
CABE-RY: A PAM-flexible dual-mutation base editor for reliable modeling of multi-nucleotide variants
Authors: Wanyu Tao, Qing Liu, Shisheng Huang, Xin Wang, Shiyuan Qu, Junfan Guo, Danfeng Ou, Guanglei Li, Yu Zhang, Xiangmin Xu, Xingxu Huang
Journal: Mol Ther Nucleic Acids
PubMed ID: 34513298
Doi: 10.1016/j.omtn.2021.07.016
Products & Services: PCR Cloning and Subcloning   
Characterization of the Role of the Neoxanthin Synthase Gene in Carotenoid Biosynthesis in Chinese Kale
Authors: Yue Jian, Chenlu Zhang, Yating Wang, Zhiqing Li, Jing Chen, Wenting Zhou, Wenli Huang, Min Jiang, Hao Zheng, Mengyao Li, Huiying Miao, Fen Zhang, Huanxiu Li, Qiaomei Wang, Bo Sun
Journal: Genes (Basel)
PubMed ID: 34440295
Doi: 10.3390/genes12081122
Products & Services: Protein Tools   
K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle
Authors: Yuanyuan Yu, Qingyun Zheng, Satchal K Erramilli, Man Pan, Seongjin Park, Yuan Xie, Jingxian Li, Jingyi Fei, Anthony A Kossiakoff, Lei Liu, Minglei Zhao
Journal: Nat Chem Biol
PubMed ID: 34239127
Doi: 10.1038/s41589-021-00823-5
Products & Services: Catalog Antibody   
Muscone suppresses gastric cancer via regulation of miRNA-145
Authors: Feng Gao, Shihai Yan, Zheng Sun, Jia Wang
Journal: Food Sci Nutr
PubMed ID: 34531985
Doi: 10.1002/fsn3.2269
Products & Services: Gene Synthesis   
The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach
Authors: Sergio Romero-Romero, Miguel Costas, Daniel-Adriano Silva Manzano, Sina Kordes, Erendira Rojas-Ortega, Cinthya Tapia, Yasel Guerra, Sooruban Shanmugaratnam, Adela Rodríguez-Romero, David Baker, Birte Höcker, D Alejandro Fernández-Velasco
Journal: J Mol Biol
PubMed ID: 34271011
Doi: 10.1016/j.jmb.2021.167153
Products & Services: Gene Synthesis   
A Cas12a-based CRISPR interference system for multigene regulation in mycobacteria
Authors: Neil Fleck, Christoph Grundner
Journal: J Biol Chem
PubMed ID: 34298016
Doi: 10.1016/j.jbc.2021.100990
Products & Services: Gene Synthesis   
Longitudinal evaluation of laboratory-based serological assays for SARS-CoV-2 antibody detection
Authors: K A Bond, E Williams, S Nicholson, S Lim, D Johnson, B Cox, M Putland, E Gardiner, E Tippett, M Graham, F Mordant, M Catton, S R Lewin, K Subbarao, B P Howden, D A Williamson
Journal: Pathology
PubMed ID: 34412859
Doi: 10.1016/j.pathol.2021.05.093
Products & Services: Catalog Antibody   
Fast and reliable detection of SARS-CoV-2 antibodies based on surface plasmon resonance
Authors: Caroline Rodrigues Basso, Camila Dantas Malossi, Amanda Haisi, Valber de Albuquerque Pedrosa, Alexandre Naime Barbosa, Rejane Tommasini Grotto, João Pessoa Araujo Junior
Journal: Anal Methods
PubMed ID: 34231576
Doi: 10.1039/d1ay00737h
Products & Services: Recombinant Proteins   
Minute-scale detection of SARS-CoV-2 using a low-cost biosensor composed of pencil graphite electrodes
Authors: Lucas F de Lima, André L Ferreira, Marcelo D T Torres, William R de Araujo, Cesar de la Fuente-Nunez
Journal: Proc Natl Acad Sci U S A
PubMed ID: 34244421
Doi: 10.1073/pnas.2106724118
Products & Services: Mammalian Expression   
Selective Inhibitors of the Inducible Nitric Oxide Synthase as Modulators of Cell Responses in LPS-Stimulated Human Monocytes
Authors: Marialucia Gallorini, Monica Rapino, Helmut Schweikl, Amelia Cataldi, Rosa Amoroso, Cristina Maccallini
Journal: Molecules
PubMed ID: 34361571
Doi: 10.3390/molecules26154419

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