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页码: 161/1028 每页显示数量

3D biomimetic platform reveals the first interactions of the embryo and the maternal blood vessels

Authors: Niraimathi Govindasamy, Hongyan Long, Hyun-Woo Jeong, Ratish Raman, Burak Özcifci, Simone Probst, Sebastian J Arnold, Kristina Riehemann, Adrian Ranga, Ralf H Adams, Britta Trappmann, Ivan Bedzhov

Journal: Dev Cell

PubMed ID: 34741805

Doi: 10.1016/j.devcel.2021.10.014

Products & Services: Proteins, Expression, Isolation and Analysis

Capillary electrophoresis-based functional genomics screening to discover novel archaeal DNA modifying enzymes

Authors: Kelly M Zatopek, Samantha L Fossa, Katharina Bilotti, Paul J Caffrey, Léa Chuzel, Alexandra M Gehring, Gregory J S Lohman, Christopher H Taron, Andrew F Gardner

Journal: Appl Environ Microbiol

PubMed ID: 34788065

Doi: 10.1128/AEM.02137-21

Products & Services: Plasmid DNA Preparation

New highly antigenic linear B cell epitope peptides from PvAMA-1 as potential vaccine candidates

Authors: Raianna F Fantin, Vanessa G Fraga, Camila A Lopes, Isabella C de Azevedo, João L Reis-Cunha, Dhelio B Pereira, Francisco P Lobo, Marcela M de Oliveira, Anderson C Dos Santos, Daniela C Bartholomeu, Ricardo T Fujiwara, Lilian L Bueno

Journal: PLoS ONE

PubMed ID: 34727117

Doi: 10.1371/journal.pone.0258637

Products & Services: Plasmid DNA Preparation

The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1

Authors: Beatriz Sanchez-Solana, Dunrui Wang, Xiaolan Qian, Parthibane Velayoudame, Dhirendra K Simanshu, Jairaj K Acharya, Douglas R Lowy

Journal: Mol Cancer

PubMed ID: 34727930

Doi: 10.1186/s12943-021-01439-y

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The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses

Authors: David M Picton, Yvette A Luyten, Richard D Morgan, Andrew Nelson, Darren L Smith, David T F Dryden, Jay C D Hinton, Tim R Blower

Journal: Nucleic Acids Res

PubMed ID: 34657954

Doi: 10.1093/nar/gkab906

Products & Services: Mutant Libraries

Effector-mediated membrane disruption controls cell death in CBASS antiphage defense

Authors: Brianna Duncan-Lowey, Nora K McNamara-Bordewick, Nitzan Tal, Rotem Sorek, Philip J Kranzusch

Journal: Mol Cell

PubMed ID: 34784509

Doi: 10.1016/j.molcel.2021.10.020

Products & Services: Mutant Libraries

Stress Induced Transcription Factors Transactivate the Herpes Simplex Virus 1 Infected Cell Protein 27 (ICP27) Transcriptional Enhancer

Authors: Jeffery B Ostler, Clinton Jones

Journal: Viruses

PubMed ID: 34835102

Doi: 10.3390/v13112296

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A mosquito AgTRIO monoclonal antibody reduces early infection of mice

Authors: Yu-Min Chuang, Xu-Dong Tang, Erol Fikrig

Journal: Infect Immun

PubMed ID: 34724388

Doi: 10.1128/IAI.00359-21

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Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization

Authors: Nikolas Friedrich, Emanuel Stiegeler, Matthias Glögl, Thomas Lemmin, Simon Hansen, Claus Kadelka, Yufan Wu, Patrick Ernst, Liridona Maliqi, Caio Foulkes, Mylène Morin, Mustafa Eroglu, Thomas Liechti, Branislav Ivan, Thomas Reinberg, Jonas V Schaefer, Umut Karakus, Stephan Ursprung, Axel Mann, Peter Rusert, Roger D Kouyos, John A Robinson, Huldrych F Günthard, Andreas Plückthun, Alexandra Trkola

Journal: Nat Commun

PubMed ID: 34795280

Doi: 10.1038/s41467-021-27075-0

Products & Services: GenParts™ DNA Fragments

Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation

Authors: Hengjun Cui, Andreas U Müller, Marc Leibundgut, Jiawen Tian, Nenad Ban, Eilika Weber-Ban

Journal: Nat Commun

PubMed ID: 34789727

Doi: 10.1038/s41467-021-26848-x

Products & Services: GenParts™ DNA Fragments

Tryptophan Side-Chain Oxidase Enzyme Suppresses Hepatocellular Carcinoma Growth through Degradation of Tryptophan

Authors: Yang Ai, Ben Wang, Shuai Xiao, Sang Luo, Yefu Wang

Journal: Int J Mol Sci

PubMed ID: 34830310

Doi: 10.3390/ijms222212428

Products & Services: Endotoxin Detection & Removal System

Germinal centre-driven maturation of B cell response to SARS-CoV-2 vaccination

Authors: Wooseob Kim, Julian Q Zhou, Alexandria J Sturtz, Stephen C Horvath, Aaron J Schmitz, Tingting Lei, Elizaveta Kalaidina, Mahima Thapa, Wafaa B Alsoussi, Alem Haile, Michael K Klebert, Teresa Suessen, Luis Parra-Rodriguez, Philip A Mudd, William D Middleton, Sharlene A Teefey, Iskra Pusic, Jane A O'Halloran, Rachel M Presti, Jackson S Turner, Ali H Ellebedy

Journal: biorxiv

PubMed ID: 34751268

Doi: 10.1101/2021.10.31.466651

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MiR-702-3p inhibits the inflammatory injury in septic H9c2 cells by regulating NOD1

Authors: Chun Liu, Yang Yang, Guiwen Liang, Aixian Zhang, Feng Xu

Journal: Transpl Immunol

PubMed ID: 34774740

Doi: 10.1016/j.trim.2021.101493

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T cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomas

Authors: Michael Kilian, Mirco Friedrich, Khwab Sanghvi, Edward Green, Stefan Pusch, Daisuke Kawauchi, Martin Löwer, Jana K Sonner, Christopher Krämer, Julia Zaman, Stefanie Jung, Michael O Breckwoldt, Gerald Willimksy, Stefan B Eichmüller, Andreas von Deimling, Wolfgang Wick, Felix Sahm, Michael Platten, Lukas Bunse

Journal: Clin Cancer Res

PubMed ID: 34782365

Doi: 10.1158/1078-0432.CCR-21-1881

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Structural insights into bifunctional thaumarchaeal crotonyl-CoA hydratase and 3-hydroxypropionyl-CoA dehydratase from Nitrosopumilus maritimus

Authors: Ebru Destan, Busra Yuksel, Bradley B Tolar, Esra Ayan, Sam Deutsch, Yasuo Yoshikuni, Soichi Wakatsuki, Christopher A Francis, Hasan DeMirci

Journal: Sci Rep

PubMed ID: 34819551

Doi: 10.1038/s41598-021-02180-8

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Proteolytic processing of plant proteins by potyvirus NIa proteases

Authors: Huogen Xiao, Etienne Lord, Hélène Sanfaçon

Journal: J Virol

PubMed ID: 34757836

Doi: 10.1128/JVI.01444-21

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Structure of native HIV-1 cores and their interactions with IP6 and CypA

Authors: Tao Ni, Yanan Zhu, Zhengyi Yang, Chaoyi Xu, Yuriy Chaban, Tanya Nesterova, Jiying Ning, Till Böcking, Michael W Parker, Christina Monnie, Jinwoo Ahn, Juan R Perilla, Peijun Zhang

Journal: Sci Adv

PubMed ID: 34797722

Doi: 10.1126/sciadv.abj5715

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Allelic variants of full-length VAR2CSA, the placental malaria vaccine candidate, differ in antigenicity and receptor binding affinity

Authors: Jonathan P Renn, Justin Y A Doritchamou, Bergeline C Nguemwo Tentokam, Robert D Morrison, Matthew V Cowles, Martin Burkhardt, Rui Ma, Niraj H Tolia, Michal Fried, Patrick E Duffy

Journal: Commun Biol

PubMed ID: 34799664

Doi: 10.1038/s42003-021-02787-7

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Multi-Antigen Outer Membrane Vesicle Engineering to Develop Polyvalent Vaccines: The Case

Authors: Enrico König, Assunta Gagliardi, Ilary Riedmiller, Chiara Andretta, Michele Tomasi, Carmela Irene, Luca Frattini, Ilaria Zanella, Francesco Berti, Alberto Grandi, Elena Caproni, Laura Fantappiè, Guido Grandi

Journal: Front Immunol

PubMed ID: 34819933

Doi: 10.3389/fimmu.2021.752168

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Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy

Authors: Jun Zheng, Xi Chen, Qiang Liu, Guisheng Zhong, Min Zhuang

Journal: J Cell Biol

PubMed ID: 34747980

Doi: 10.1083/jcb.202103156

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Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice

Authors: Cherng-Shyang Chang, Yi-Chu Liao, Chih-Ting Huang, Chiao-Mei Lin, Chantal Hoi Yin Cheung, Jhen-Wei Ruan, Wen-Hsuan Yu, Yi-Ting Tsai, I-Jung Lin, Chien-Hsun Huang, Jong-Shian Liou, Ya-Hsien Chou, Hung-Jen Chien, Hsiao-Li Chuang, Hsueh-Fen Juan, Hsuan-Cheng Huang, Hong-Lin Chan, Yu-Chieh Liao, Shiue-Cheng Tang, Yu-Wen Su, Tse-Hua Tan, Andreas J Bäumler, Cheng-Yuan Kao

Journal: Cell Rep

PubMed ID: 34818535

Doi: 10.1016/j.celrep.2021.110016

Products & Services: Recombinant Proteins

Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains*

Authors: Karen T Elvers, Magdalena Lipka-Lloyd, Rebecca C Trueman, Benjamin D Bax, Youcef Mehellou

Journal: Chembiochem

PubMed ID: 34726826

Doi: 10.1002/cbic.202100441

Products & Services: Gene Synthesis

Pharmacological modulation of the cAMP signaling of two isoforms of melanocortin-3 receptor by melanocortin receptor accessory proteins in the tetrapod Xenopus laevis

Authors: Ying Xu, Lei Li, Jihong Zheng, Meng Wang, Bopei Jiang, Yue Zhai, Liumei Lu, Cong Zhang, Zhe Kuang, Xiaomei Yang, Li-Na Jin, Gufa Lin, Chao Zhang

Journal: Endocr Connect

PubMed ID: 34678757

Doi: 10.1530/EC-21-0179

Products & Services: Recombinant Proteins

Structure of Rift Valley fever virus RNA-dependent RNA polymerase

Authors: Xue Wang, Cuixia Hu, Wei Ye, Jia Wang, Xiaofei Dong, Jie Xu, Xiaorong Li, Manfeng Zhang, Hongyun Lu, Fanglin Zhang, Wei Wu, Shaodong Dai, Hong-Wei Wang, Zhongzhou Chen

Journal: J Virol

PubMed ID: 34787453

Doi: 10.1128/JVI.01713-21

Products & Services: Proteins, Expression, Isolation and Analysis

Alpha adaptins show isoform-specific association with neurofibrillary tangles in Alzheimer's disease

Authors: Sukanya Srinivasan, Jozsef Gal, Adam Bachstetter, Peter T Nelson

Journal: Neuropathol Appl Neurobiol

PubMed ID: 34820873

Doi: 10.1111/nan.12776

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ABCC2 is a functional receptor of Bacillus thuringiensis Cry1Ca in Spodoptera litura

Authors: Xue Yao, Chen Liu, Yunpeng Duan, Shiheng An, Jizhen Wei, Gemei Liang

Journal: Int J Biol Macromol

PubMed ID: 34861271

Doi: 10.1016/j.ijbiomac.2021.11.174

Products & Services: Recombinant Proteins

Overcome Chemoresistance: Biophysical and Structural Analysis of Synthetic FHIT-Derived Peptides

Authors: Maria Carmina Scala, Simone Di Micco, Delia Lanzillotta, Simona Musella, Veronica Di Sarno, Barbara Parrino, Stella Maria Casciofierro, Giuseppe Bifulco, Francesco Trapasso, Pietro Campiglia, Marina Sala

Journal: Front Mol Biosci

PubMed ID: 34901149

Doi: 10.3389/fmolb.2021.715263

Products & Services: Recombinant Proteins

Molecular characterization of substrate-induced ubiquitin transfer by UBR7-PHD finger, a newly identified histone H2BK120 ubiquitin ligase

Authors: Anirban Dasgupta, Payel Mondal, Sambit Dalui, Chandrima Das, Siddhartha Roy

Journal: FEBS J

PubMed ID: 34739193

Doi: 10.1111/febs.16262

Products & Services: Recombinant Proteins

Gamma delta TCR anti-CD3 bispecific molecules (GABs) as novel immunotherapeutic compounds

Authors: Eline van Diest, Patricia Hernández López, Angelo D Meringa, Anna Vyborova, Froso Karaiskaki, Sabine Heijhuurs, Jan Gumathi Bormin, Sanne van Dooremalen, Mara J T Nicolasen, Lucrezia C D E Gatti, Inez Johanna, Trudy Straetemans, Zsolt Sebestyén, Dennis X Beringer, Jürgen Kuball

Journal: J Immunother Cancer

PubMed ID: 34815357

Doi: 10.1136/jitc-2021-003850

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The impact of reductants on the catalytic efficiency of a lytic polysaccharide monooxygenase and the special role of dehydroascorbic acid

Authors: Anton A Stepnov, Idd A Christensen, Zarah Forsberg, Finn L Aachmann, Gaston Courtade, Vincent G H Eijsink

Journal: FEBS Lett

PubMed ID: 34845720

Doi: 10.1002/1873-3468.14246

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Structural characterization of the porcine adeno-associated virus Po1 capsid protein binding to the nuclear trafficking protein importin alpha

Authors: Mikayla Hoad, Justin A Roby, Jade K Forwood

Journal: FEBS Lett

PubMed ID: 34661283

Doi: 10.1002/1873-3468.14209

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A simple PCR-RFLP method for identification and detection of medicinal toad and its crude drug even with serious degradation of DNA

Authors: Jiao Liu, Xinyi Shao, Ziying Zhou, Miao Lei, Mingyu Xia, Dong Wang

Journal: J Pharm Biomed Anal

PubMed ID: 34864355

Doi: 10.1016/j.jpba.2021.114495

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1,800 MHz Radiofrequency Electromagnetic Irradiation Impairs Neurite Outgrowth With a Decrease in Rap1-GTP in Primary Mouse Hippocampal Neurons and Neuro2a Cells

Authors: Yanqi Li, Ping Deng, Chunhai Chen, Qinlong Ma, Huifeng Pi, Mindi He, Yonghui Lu, Peng Gao, Chao Zhou, Zhixin He, Yanwen Zhang, Zhengping Yu, Lei Zhang

Journal: Front Public Health

PubMed ID: 34881219

Doi: 10.3389/fpubh.2021.771508

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Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy

Authors: Cristina Gil-Cruz, Christian Perez-Shibayama, Angelina De Martin, Francesca Ronchi, Katrien van der Borght, Rebekka Niederer, Lucas Onder, Mechthild Lütge, Mario Novkovic, Veronika Nindl, Gustavo Ramos, Markus Arnoldini, Emma M C Slack, Valérie Boivin-Jahns, Roland Jahns, Madeleine Wyss, Catherine Mooser, Bart N Lambrecht, Micha T Maeder, Hans Rickli, Lukas Flatz, Urs Eriksson, Markus B Geuking, Kathy D McCoy, Burkhard Ludewig

Journal: Science

PubMed ID: 31727837

Doi: 10.1126/science.aav3487

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Two energy barriers and a transient intermediate state determine the unfolding and folding dynamics of cold shock protein

Authors: Haiyan Hong, Zilong Guo, Hao Sun , Ping Yu , Huanhuan Su , Xuening Ma & Hu Chen

Journal: Communications Chemistry

Doi: doi.org/10.1038/s42004-021-00592-1

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Performance Evaluation of the BZ COVID-19 Neutralizing Antibody Test for the Culture-Free and Rapid Detection of SARS-CoV-2 Neutralizing Antibodies

Authors: Bo Kyeung Jung, Jung Yoon, Joon-Yong Bae, Jeonghun Kim, Man-Seong Park, Suk Yong Lee, Chae Seung Lim

Journal: Diagnostics (Basel)

PubMed ID: 34943430

Doi: 10.3390/diagnostics11122193

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Picomolar inhibition of SARS-CoV-2 variants of concern by an engineered ACE2-IgG4-Fc fusion protein

Authors: Hristo L Svilenov, Julia Sacherl, Alwin Reiter, Lisa S Wolff, Cho-Chin Cheng, Marcel Stern, Vincent Grass, Martin Feuerherd, Frank-Peter Wachs, Nicole Simonavicius, Susanne Pippig, Florian Wolschin, Oliver T Keppler, Johannes Buchner, Carsten Brockmeyer, Ulrike Protzer

Journal: Antiviral Res

PubMed ID: 34774603

Doi: 10.1016/j.antiviral.2021.105197

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Kinetics of anti-SARS-CoV-2 neutralizing antibodies development after BNT162b2 vaccination in patients with amyloidosis and the impact of therapy

Authors: Efstathios Kastritis, Evangelos Terpos, Zoi Evangelakou, Foteini Theodorakakou, Despina Fotiou, Maria S Manola, Despoina D Gianniou, Tina Bagratuni, Nikolaos Kanellias, Magdalini Migkou, Maria Gavriatopoulou, Ioannis P Trougakos, Meletios A Dimopoulos

Journal: Am J Hematol

PubMed ID: 34778995

Doi: 10.1002/ajh.26406

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Backbone H, N, and C resonance assignments of the non-structural protein NS2B of Zika virus

Authors: Beatriz Rosa Penna, Danielle Maria P de Oliveira, Cristiane Dinis Anobom, Ana Paula Valente

Journal: Biomol NMR Assign

PubMed ID: 34817802

Doi: 10.1007/s12104-021-10055-2

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JNK/Itch Axis Mediates the Lipopolysaccharide-Induced Ubiquitin-Proteasome-Dependent Degradation of Ferritin Light Chain in Murine Macrophage Cells

Authors: Shufen He, Jianqi Xue, Pengxiu Cao, Jianyuan Hou, Yan Cui, Jing Chang, Liying Huang, Yu Han, Xianglin Duan, Ke Tan, Yumei Fan

Journal: Inflammation

PubMed ID: 34837126

Doi: 10.1007/s10753-021-01603-y

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The concentration of brain homogenates with the Amicon Ultra Centrifugal filters

Authors: Joshua Yang, Rachita K Sumbria

Journal: MethodsX

PubMed ID: 35004217

Doi: 10.1016/j.mex.2021.101584

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Characterization of Anti-Ana o 3 Monoclonal Antibodies and Their Application in Comparing Brazilian Cashew Cultivars

Authors: Christopher P Mattison, Barry Vant-Hull, Ana Cecilia Ribeiro de Castro, Heidi J Chial, Yvette Bren-Mattison, Peter J Bechtel, Edy Sousa de Brito

Journal: Antibodies (Basel)

PubMed ID: 34939998

Doi: 10.3390/antib10040046

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Endotoxin contamination in commercially available Cas9 proteins potentially induces T-cell mediated responses

Authors: Vijaya L Simhadri, Joseph R McGill, Zuben E Sauna

Journal: Gene Ther

PubMed ID: 34744169

Doi: 10.1038/s41434-021-00301-6

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Cholecystokinin-B Receptor-Targeted Nanoparticle for Imaging and Detection of Precancerous Lesions in the Pancreas

Authors: Jill P Smith, Hong Cao, Elijah F Edmondson, Siva Sai Krishna Dasa, Stephan T Stern

Journal: Biomolecules

PubMed ID: 34944412

Doi: 10.3390/biom11121766

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Biochemical basis for an interaction between SNX27 and the flexible SNX1 N-terminus

Authors: Mintu Chandra, Brett M Collins, Lauren P Jackson

Journal: Adv Biol Regul

PubMed ID: 34866035

Doi: 10.1016/j.jbior.2021.100842

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Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy

Authors: Sheng-Li Ming , Shuang Zhang , Qi Wang , Lei Zeng , Lu-Yu Zhou , Meng-Di Wang , Ying-Xian Ma , Li-Qiang Han , Kai Zhong , He-Shui Zhu , Yi-Lin Bai , Guo-Yu Yang , Jiang Wang , Bei-Bei Chu

Journal: Autophagy

PubMed ID: 34822318

Doi: 10.1080/15548627.2021.2002101

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Novel xylan-degrading enzymes from polysaccharide utilizing loci of Prevotella copri DSM18205

Authors: Javier A Linares-Pastén , Johan Sebastian Hero , José Horacio Pisa , Cristina Teixeira , Margareta Nyman , Patrick Adlercreutz , M Alejandra Martinez , Eva Nordberg Karlsson

Journal: Glycobiology

PubMed ID: 34142143

Doi: 10.1093/glycob/cwab056

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Wilavidin - a novel member of the avidin family that forms unique biotin-binding hexamers

Authors: Orly Avraham, Edward A Bayer, Oded Livnah

Journal: FEBS J

PubMed ID: 34726340

Doi: 10.1111/febs.16259

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Phylogenetic Analysis of the Plant U2 snRNP Auxiliary Factor Large Subunit A Gene Family in Response to Developmental Cues and Environmental Stimuli

Authors: Shuai Lu, Cong Gao, Yongzhou Wang, Yingying He, Junrong Du, Moxian Chen, Hua Zhao, Hui Fang, Baohua Wang, Yunying Cao

Journal: Front Plant Sci

PubMed ID: 34868124

Doi: 10.3389/fpls.2021.739671

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Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants

Authors: Matthew McCallum, Alexandra C Walls, Kaitlin R Sprouse, John E Bowen, Laura E Rosen, Ha V Dang, Anna De Marco, Nicholas Franko, Sasha W Tilles, Jennifer Logue, Marcos C Miranda, Margaret Ahlrichs, Lauren Carter, Gyorgy Snell, Matteo Samuele Pizzuto, Helen Y Chu, Wesley C Van Voorhis, Davide Corti, David Veesler

Journal: Science

PubMed ID: 34751595

Doi: 10.1126/science.abl8506

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