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The concentration of brain homogenates with the Amicon Ultra Centrifugal filters

Authors: Joshua Yang, Rachita K Sumbria

Journal: MethodsX

PubMed ID: 35004217

Doi: 10.1016/j.mex.2021.101584

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Conservation and Divergence of the Genes Related to Flowering and Circadian Rhythm in

Authors: Yuxi Chen, Rijin Zhou, Qiong Hu, Wenliang Wei, Jia Liu

Journal: Front Plant Sci

PubMed ID: 34880887

Doi: 10.3389/fpls.2021.760379

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Cancer cells under immune attack acquire CD47-mediated adaptive immune resistance independent of the myeloid CD47-SIRPα axis

Authors: Mark A J M Hendriks, Isabel Britsch, Xiurong Ke, Anne P van Wijngarden, Douwe F Samplonius, Emily M Ploeg, Wijnand Helfrich

Journal: Oncoimmunology

PubMed ID: 34858730

Doi: 10.1080/2162402X.2021.2005344

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WRKY2 and WRKY10 regulate the circadian expression of during the day through interactions with CCA1/LHY and phyB

Authors: Shulei Wang, Qingbin Sun, Min Zhang, Chengzhu Yin, Min Ni

Journal: Plant Commun

PubMed ID: 35529947

Doi: 10.1016/j.xplc.2021.100265

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Mitochondrial Localization Signal of Porcine Circovirus Type 2 Capsid Protein Plays a Critical Role in Cap-Induced Apoptosis

Authors: Wanting Yu, Yuao Sun, Qing He, Chaoying Sun, Tian Dong, Luhua Zhang, Yang Zhan, Naidong Wang, Yi Yang, Yujie Sun

Journal: Vet Sci

PubMed ID: 34822645

Doi: 10.3390/vetsci8110272

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Optimized biosynthesis of santalenes and santalols in Saccharomyces cerevisiae

Authors: Yuchen Wang, Xiaowei Gong, Fan Li, Shasha Zuo, Minggang Li, Jiangyuan Zhao, Xiulin Han, Mengliang Wen

Journal: Appl Microbiol Biotechnol

PubMed ID: 34738171

Doi: 10.1007/s00253-021-11661-9

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Programmable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides

Authors: Ibraheem Alshareedah, Mahdi Muhammad Moosa, Matthew Pham, Davit A Potoyan, Priya R Banerjee

Journal: Nat Commun

PubMed ID: 34785657

Doi: 10.1038/s41467-021-26733-7

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Branched ubiquitin chain binding and deubiquitination by UCH37 facilitate proteasome clearance of stress-induced inclusions

Authors: Aixin Song, Zachary Hazlett, Dulith Abeykoon, Jeremy Dortch, Andrew Dillon, Justin Curtiss, Sarah Bollinger Martinez, Christopher P Hill, Clinton Yu, Lan Huang, David Fushman, Robert E Cohen, Tingting Yao

Journal: Elife

PubMed ID: 34761751

Doi: 10.7554/eLife.72798

Products & Services: Proteins, Expression, Isolation and Analysis

Characterization of a lytic polysaccharide monooxygenase from Aspergillus fumigatus shows functional variation among family AA11 fungal LPMOs

Authors: Fredrik Gjerstad Støpamo, Åsmund Kjendseth Røhr, Sophanit Mekasha, Dejan M Petrović, Anikó Várnai, Vincent G H Eijsink

Journal: J Biol Chem

PubMed ID: 34798071

Doi: 10.1016/j.jbc.2021.101421

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Recombinant Human HPS Protects Mice and Nonhuman Primates from Acute Liver Injury

Authors: Yang Yang, Huali Zhai, Yue Wan, Xiaofang Wang, Hui Chen, Lihou Dong, Taoyun Liu, Guifang Dou, Chutse Wu, Miao Yu

Journal: Int J Mol Sci

PubMed ID: 34884691

Doi: 10.3390/ijms222312886

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Expression and purification of a native Thy1-single-chain variable fragment for use in molecular imaging

Authors: Natacha Jugniot, Rakesh Bam, Ramasamy Paulmurugan

Journal: Sci Rep

PubMed ID: 34845270

Doi: 10.1038/s41598-021-02445-2

Products & Services: Proteins, Expression, Isolation and Analysis

Diacylglycerol kinase A is essential for polymyxin resistance provided by EptA, MCR-1 and other lipid A phosphoethanolamine transferases

Authors: Alexandria B Purcell, Bradley J Voss, M Stephen Trent

Journal: J Bacteriol

PubMed ID: 34843376

Doi: 10.1128/JB.00498-21

Products & Services: Proteins, Expression, Isolation and Analysis

Comparative proteomics reveals Cryptosporidium parvum manipulation of the host cell molecular expression and immune response

Authors: Teng Li, Hua Liu, Nan Jiang, Yiluo Wang, Ying Wang, Jing Zhang, Yujuan Shen, Jianping Cao

Journal: PLoS Negl Trop Dis

PubMed ID: 34818332

Doi: 10.1371/journal.pntd.0009949

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Nde1 is a Rab9 effector for loading late endosomes to cytoplasmic dynein motor complex

Authors: Yifan Zhang, Ziyue Chen, Fang Wang, Honghua Sun, Xueliang Zhu, Jianping Ding, Tianlong Zhang

Journal: Structure

PubMed ID: 34793709

Doi: 10.1016/j.str.2021.10.013

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Gasdermin D inhibition confers antineutrophil mediated cardioprotection in acute myocardial infarction

Authors: Kai Jiang, Zizhuo Tu, Kun Chen, Yue Xu, Feng Chen, Sheng Xu, Tingting Shi, Jie Qian, Lan Shen, John Hwa, Dandan Wang, Yaozu Xiang

Journal: J Clin Invest

PubMed ID: 34752417

Doi: 10.1172/JCI151268

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Highly portable quantitative screening test for prostate-specific antigen at point of care

Authors: Balaji Srinivasan, David M Nanus, David Erickson, Saurabh Mehta

Journal: Curr Res Biotechnol

PubMed ID: 35083431

Doi: 10.1016/j.crbiot.2021.11.003

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Performance Characteristics of High-Throughput Serologic Assays for Severe Acute Respiratory Syndrome Coronavirus 2 with Food and Drug Administration Emergency Use Authorization: A Review

Authors:

Journal: Clin Lab Med

PubMed ID: 35153046

Doi: 10.1016/j.cll.2021.10.006

Piezo2 mechanosensitive ion channel is located to sensory neurons and nonneuronal cells in rat peripheral sensory pathway: implications in pain

Authors: Seung Min Shin, Francie Moehring, Brandon Itson-Zoske, Fan Fan, Cheryl L Stucky, Quinn H Hogan, Hongwei Yu

Journal: Pain

PubMed ID: 34285153

Doi: 10.1097/j.pain.0000000000002356

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Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses

Authors: Mohamad-Gabriel Alameh, István Tombácz, Emily Bettini, Katlyn Lederer, Chutamath Sittplangkoon, Joel R Wilmore, Brian T Gaudette, Ousamah Y Soliman, Matthew Pine, Philip Hicks, Tomaz B Manzoni, James J Knox, John L Johnson, Dorottya Laczkó, Hiromi Muramatsu, Benjamin Davis, Wenzhao Meng, Aaron M Rosenfeld, Shirin Strohmeier, Paulo J C Lin, Barbara L Mui, Ying K Tam, Katalin Karikó, Alain Jacquet, Florian Krammer, Paul Bates, Michael P Cancro, Drew Weissman, Eline T Luning Prak, David Allman, Michela Locci, Norbert Pardi

Journal: Immunity

PubMed ID: 34852217

Doi: 10.1016/j.immuni.2021.11.001

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Refinement and Neutralization Evaluation of the F(ab') Type of Antivenom against the Deadly Jellyfish Toxins

Authors: Rongfeng Li, Huahua Yu, Aoyu Li, Chunlin Yu, Pengcheng Li

Journal: Int J Mol Sci

PubMed ID: 34884477

Doi: 10.3390/ijms222312672

Products & Services: Proteins, Expression, Isolation and Analysis

Role of cytochrome P450 2C8 genetic polymorphism and epoxygenase uncoupling in periodontal remodelling affecting orthodontic treatment

Authors: Sabrina Yamoune, Katharina Wintz, Christian Niederau, Rogerio B Craveiro, Michael Wolf, Julia Stingl

Journal: Basic Clin Pharmacol Toxicol

PubMed ID: 34740282

Doi: 10.1111/bcpt.13681

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Endotoxin Acts Synergistically With Clostridioides difficile Toxin B to Increase Interleukin 1β Production: A Potential Role for the Intestinal Biome in Modifying the Severity of C difficile Colitis

Authors: Pyae Htwe, Htay Aung, Bohm Kywe, Phyu T Niang, Thar Sann Oo, Sindhu Monhandas, Libusha Kelly, David L Goldman

Journal: J Infect Dis

PubMed ID: 33780547

Doi: 10.1093/infdis/jiab165

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Modified cyclodextrin-based nanoparticles mediated delivery of siRNA for huntingtin gene silencing across an in vitro BBB model

Authors: Monique C P Mendonça, Michael F Cronin, John F Cryan, Caitriona M O'Driscoll

Journal: Eur J Pharm Biopharm

PubMed ID: 34793942

Doi: 10.1016/j.ejpb.2021.11.003

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Potential role of BAY11-7082, a NF-κB blocker inhibiting experimental autoimmune encephalomyelitis in C57BL/6J mice via declining NLRP3 inflammasomes

Authors: Yue Lang, Fengna Chu, Lingling Liu, Chao Zheng, Chunrong Li, Donghui Shen, Shan Liu, Weiguanliu Zhang, Li Cui, Jie Zhu

Journal: Clin Exp Immunol

PubMed ID: 35020839

Doi: 10.1093/cei/uxab022

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TGF-β1-overexpressing mesenchymal stem cells reciprocally regulate Th17/Treg cells by regulating the expression of IFN-γ

Authors: Ruixue Li, Renyong Wang, Shijie Zhong, Farhan Asghar, Tiehan Li, Lei Zhu, Hong Zhu

Journal: Open Life Sci

PubMed ID: 34761110

Doi: 10.1515/biol-2021-0118

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Structure-based engineering of an antiangiogenic scFv antibody for soluble production in E coli without loss of activity

Authors: Melis Denizci Öncü, Bertan Koray Balcıoğlu, Beytullah Özgür, Hasan Ümit Öztürk, Müge Serhatlı, Şeyma Işık, Berrin Erdağ, Gizem Dinler Doğanay, Aylin Özdemir Bahadır

Journal: Biotechnol Appl Biochem

PubMed ID: 34694021

Doi: 10.1002/bab.2273

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Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling

Authors: Anna Spier, Michael G Connor, Thomas Steiner, Filipe Carvalho, Pascale Cossart, Wolfgang Eisenreich, Timothy Wai, Fabrizia Stavru

Journal: Cell Rep

PubMed ID: 34758302

Doi: 10.1016/j.celrep.2021.109989

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Quantitative contributions of TNF receptor superfamily members to CD8 T-cell responses

Authors: John Nguyen, Johannes Pettmann, Philipp Kruger, Omer Dushek

Journal: Mol Syst Biol

PubMed ID: 34806839

Doi: 10.15252/msb.202110560

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Accelerated discovery of novel glycoside hydrolases using targeted functional profiling and selective pressure on the rumen microbiome

Authors: André L A Neves, Jiangkun Yu, Yutaka Suzuki, Marisol Baez-Magana, Elena Arutyunova, Eóin O'Hara, Tim McAllister, Kim H Ominski, M Joanne Lemieux, Le Luo Guan

Journal: Microbiome

PubMed ID: 34814938

Doi: 10.1186/s40168-021-01147-1

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CD4+ effector T cells accelerate Alzheimer's disease in mice

Authors: Jatin Machhi, Pravin Yeapuri, Yaman Lu, Emma Foster, Rupesh Chikhale, Jonathan Herskovitz, Krista L Namminga, Katherine E Olson, Mai Mohamed Abdelmoaty, Ju Gao, Rolen M Quadros, Tomomi Kiyota, Liang Jingjing, Bhavesh D Kevadiya, Xinglong Wang, Yutong Liu, Larisa Y Poluektova, Channabasavaiah B Gurumurthy, R Lee Mosley, Howard E Gendelman

Journal: J Neuroinflammation

PubMed ID: 34798897

Doi: 10.1186/s12974-021-02308-7

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Long noncoding RNA CRART16 confers 5-FU resistance in colorectal cancer cells by sponging miR-193b-5p

Authors: Jingui Wang, Xiaoqian Zhang, Junling Zhang, Shangwen Chen, Jing Zhu, Xin Wang

Journal: Cancer Cell Int

PubMed ID: 34844630

Doi: 10.1186/s12935-021-02353-5

Products & Services: Proteins, Expression, Isolation and Analysis

Calcium-Responsive Diguanylate Cyclase CasA Drives Cellulose-Dependent Biofilm Formation and Inhibits Motility in Vibrio fischeri

Authors: Alice H Tischler, Michael E Vanek, Natasha Peterson, Karen L Visick

Journal: MBio

PubMed ID: 34749532

Doi: 10.1128/mBio.02573-21

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Malaria Parasite Stress Tolerance Is Regulated by DNMT2-Mediated tRNA Cytosine Methylation

Authors: Elie Hammam, Ameya Sinha, Sebastian Baumgarten, Flore Nardella, Jiaqi Liang, Samia Miled, Frédéric Bonhomme, Diane Erdmann, Benoit Arcangioli, Paola B Arimondo, Peter Dedon, Peter Preiser, Artur Scherf

Journal: MBio

PubMed ID: 34724812

Doi: 10.1128/mBio.02558-21

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MiR-574-5P, miR-1827, and miR-4429 as Potential Biomarkers for Schizophrenia

Authors: Omran Davarinejad, Sajad Najafi, Hossein Zhaleh, Farzaneh Golmohammadi, Farnaz Radmehr, Mostafa Alikhani, Reza Heidari Moghadam, Yazdan Rahmati

Journal: J Mol Neurosci

PubMed ID: 34811713

Doi: 10.1007/s12031-021-01945-0

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Involvement of the Heat Shock Protein HtpG of Typhimurium in Infection and Proliferation in Hosts

Authors: Tao Dong, Weiwei Wang, Minhao Xia, Shujie Liang, Guangzhong Hu, Hui Ye, Qingyun Cao, Zemin Dong, Changming Zhang, Dingyuan Feng, Jianjun Zuo

Journal: Front Cell Infect Microbiol

PubMed ID: 34869065

Doi: 10.3389/fcimb.2021.758898

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Tegument Protein pp150 Sequence-Specific Peptide Blocks Cytomegalovirus Infection

Authors: Dipanwita Mitra, Mohammad H Hasan, John T Bates, Gene L Bidwell, Ritesh Tandon

Journal: Viruses

PubMed ID: 34835083

Doi: 10.3390/v13112277

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Agonist/Antagonist Activity of Oxytocin Variants Obtained from Free Cyclic Peptide Libraries Generated via Amino Acid Substitution

Authors: Remi Kinoshita, Ikko Kozaki, Kazunori Shimizu, Takahiro Shibata, Akihito Ochiai, Hiroyuki Honda

Journal: ACS Omega

PubMed ID: 34841168

Doi: 10.1021/acsomega.1c04982

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Structural and Functional Characterization of a Biliverdin-Binding Near-Infrared Fluorescent Protein From the Serpin Superfamily

Authors: Kyrylo Yu Manoilov, Agnidipta Ghosh, Steven C Almo, Vladislav V Verkhusha

Journal: J Mol Biol

PubMed ID: 34798132

Doi: 10.1016/j.jmb.2021.167359

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Recognition of Variants of Concern by Antibodies and T Cells Induced by a SARS-CoV-2 Inactivated Vaccine

Authors: Felipe Melo-González, Jorge A Soto, Liliana A González, Jorge Fernández, Luisa F Duarte, Bárbara M Schultz, Nicolás M S Gálvez, Gaspar A Pacheco, Mariana Ríos, Yaneisi Vázquez, Daniela Rivera-Pérez, Daniela Moreno-Tapia, Carolina Iturriaga, Omar P Vallejos, Roslye V Berríos-Rojas, Guillermo Hoppe-Elsholz, Marcela Urzúa, Nicole Bruneau, Rodrigo A Fasce, Judith Mora, Alba Grifoni, Alessandro Sette, Daniela Weiskopf, Gang Zeng, Weining Meng, José V González-Aramundiz, Pablo A González, Katia Abarca, Eugenio Ramírez, Alexis M Kalergis, Susan M Bueno

Journal: Front Immunol

PubMed ID: 34858404

Doi: 10.3389/fimmu.2021.747830

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Alternative Methods to Detect Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies

Authors: Rashmi Patel, Siddharth Khare, Vinay S Mahajan

Journal: Clin Lab Med

PubMed ID: 35153048

Doi: 10.1016/j.cll.2021.10.007

A Mycobacteriophage-Based Vaccine Platform: SARS-CoV-2 Antigen Expression and Display

Authors: Krista G Freeman, Katherine S Wetzel, Yu Zhang, Kira M Zack, Deborah Jacobs-Sera, Sara M Walters, Dominique J Barbeau, Anita K McElroy, John V Williams, Graham F Hatfull

Journal: Microorganisms

PubMed ID: 34946016

Doi: 10.3390/microorganisms9122414

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Nanoparticular CpG-adjuvanted SARS-CoV-2 S1 protein elicits broadly neutralizing and Th1-biased immunoreactivity in mice

Authors: Hui-Tsu Lin, Cheng-Cheung Chen, Der-Jiang Chiao, Tein-Yao Chang, Xin-An Chen, Jenn-Jong Young, Szu-Cheng Kuo

Journal: Int J Biol Macromol

PubMed ID: 34774590

Doi: 10.1016/j.ijbiomac.2021.11.020

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Nanovaccines Mediated Subcutis-to-Intestine Cascade for Improved Protection against Intestinal Infections

Authors: Xiaofang Zhong, Guangsheng Du, Xuanyu Wang, Yangsen Ou, Hairui Wang, Yining Zhu, Xinyan Hao, Zhiqiang Xie, Yuandong Zhang, Tao Gong, Zhirong Zhang, Xun Sun

Journal: Small

PubMed ID: 34825482

Doi: 10.1002/smll.202105530

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Baculovirus Vectors Induce the Production of Interferons in Swine: Their Potential in the Development of Antiviral Strategies

Authors: Guido Nicolás Molina, Sabrina Amalfi, Ignacio Otero, Oscar Taboga, María Paula Molinari

Journal: Vet Sci

PubMed ID: 34822651

Doi: 10.3390/vetsci8110278

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Metallothionein 3-Zinc Axis Suppresses Caspase-11 Inflammasome Activation and Impairs Antibacterial Immunity

Authors: Debabrata Chowdhury, Jason C Gardner, Abhijit Satpati, Suba Nookala, Santhosh Mukundan, Aleksey Porollo, Julio A Landero Figueroa, Kavitha Subramanian Vignesh

Journal: Front Immunol

PubMed ID: 34867993

Doi: 10.3389/fimmu.2021.755961

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Long Non-Coding RNA Regulates Neuronal Differentiation of Neural Stem Cells During Brain Development

Authors: Elpinickie Ninou, Artemis Michail, Panagiotis K Politis

Journal: Front Cell Dev Biol

PubMed ID: 34900989

Doi: 10.3389/fcell.2021.726857

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Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos

Authors: Raghuvir Viswanatha, Enzo Mameli, Jonathan Rodiger, Pierre Merckaert, Fabiana Feitosa-Suntheimer, Tonya M Colpitts, Stephanie E Mohr, Yanhui Hu, Norbert Perrimon

Journal: Nat Commun

PubMed ID: 34819517

Doi: 10.1038/s41467-021-27129-3

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An Efficient Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)/CRISPR-Associated Protein 9 Mutagenesis System for Oil Palm ()

Authors: Wan-Chin Yeap, Muhammad Rashdan Muad, David Ross Appleton

Journal: Front Plant Sci

PubMed ID: 34880893

Doi: 10.3389/fpls.2021.773656

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SARS-CoV-2 Spike Protein and Its Receptor Binding Domain Promote a Proinflammatory Activation Profile on Human Dendritic Cells

Authors: Dante Barreda, César Santiago, Juan R Rodríguez, José F Rodríguez, José M Casasnovas, Isabel Mérida, Antonia Ávila-Flores

Journal: Cells

PubMed ID: 34943787

Doi: 10.3390/cells10123279

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Increase in Ischemia-Modified Albumin and Pregnancy-Associated Plasma Protein-A in COVID-19 Patients

Authors: Belén G Sanchez, Jose M Gasalla, Manuel Sánchez-Chapado, Alicia Bort, Inés Diaz-Laviada

Journal: J Clin Med

PubMed ID: 34884175

Doi: 10.3390/jcm10235474

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