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Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis
Authors: Brandon M Lane, Megan Chryst-Stangl, Guanghong Wu, Mohamed Shalaby, Sherif El Desoky, Claire C Middleton, Kinsie Huggins, Amika Sood, Alejandro Ochoa, Andrew F Malone, Ricardo Vancini, Sara E Miller, Gentzon Hall, So Young Kim, David N Howell, Jameela A Kari, Rasheed Gbadegesin
Journal: JCI Insight
PubMed ID: 34874915
Doi: 10.1172/jci.insight.152102
Products & Services: Gene Synthesis   
The large nonstructural protein (NS1) of the human bocavirus 1 (HBoV1) directly interacts with Ku70, which plays an important role in virus replication in human airway epithelia
Authors: Liting Shao, Kang Ning, Jianke Wang, Fang Cheng, Shengqi Wang, Jianming Qiu
Journal: J Virol
PubMed ID: 34878919
Doi: 10.1128/JVI.01840-21
Identification of HLA-A2 restricted CD8+ T cell epitopes in SARS-CoV-2 structural proteins
Authors: Jieping Deng , Junping Pan, Minghui Qiu, Lipeng Mao , Zhigang Wang , Guodong Zhu , Lijuan Gao , Jun Su , Yutian Hu , Oscar Junhong Luo , Guobing Chen , Pengcheng Wang
Journal: J Leukoc Biol
PubMed ID: 34231935
Doi: 10.1002/JLB.4MA0621-020R
Products & Services: Peptide Synthesis   
Heterologous prime-boost with AdC68- and mRNA-based COVID-19 vaccines elicit potent immune responses in mice
Authors: Wenjuan Li , Xingxing Li , Danhua Zhao , Jingjing Liu , Ling Wang , Miao Li , Xinyu Liu , Jia Li , Xiaohong Wu , Yuhua Li
Journal: Signal Transduct Target Ther
PubMed ID: 34903732
Doi: 10.1038/s41392-021-00843-6
Products & Services: Peptide Library Services   
Nano-immobilization of PETase enzyme for enhanced polyethylene terephthalate biodegradation
Authors: Yunpu Jia , Nadia A. Samak , Xuemi Hao , Zheng Chen , Gama Yang , Xuhao Zhao , Tingzhen Mu , Maohua Yang , Jianmin Xing
Journal: Biochemical Engineering Journal
Doi: 10.1016/j.bej.2021.108205
Products & Services: DNA Sequencing   
Cell-Penetrating Antimicrobial Peptides Derived from an Atypical Staphylococcal δ-Toxin
Authors: Kathyana Deeyagahage, Antonio Ruzzini
Journal: Microbiol Spectr
PubMed ID: 34937169
Doi: 10.1128/spectrum.01584-21
Products & Services: Peptide Synthesis   
SARS-CoV-2 prevalence and immunity: a hospital-based study from Malawi
Authors: C Meinus, R Singer, B Nandi, O Jagot, B Becker-Ziaja, B Karo, B Mvula, A Jansen, J Baumann, A Schultz
Journal: Int J Infect Dis
PubMed ID: 34929356
Doi: 10.1016/j.ijid.2021.12.336
Products & Services: Protein Reagents and Products   
Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine (CoronaVac) in inadvertently vaccinated healthy children
Authors: Eder Gatti Fernandes, Giselle Ibette Silva López-Lopes, Valeria Oliveira Silva, Rosemeire Yamashiro, Karen Cristina Rolim Madureira, Juliana Failde Gallo, José Angelo Lindoso, Helena Keico Sato, Núbia Virginia D'Avila Limeira de Araujo, Maria Ligia Bacciotte Ramos Nerger, Luis Fernando Macedo Brigido
Journal: Rev Inst Med Trop Sao Paulo
PubMed ID: 34878041
Doi: 10.1590/S1678-9946202163083
Products & Services: Protein Reagents and Products   
Inhibition of micro RNA miR-122-5p prevents lipopolysaccharide-induced myocardial injury by inhibiting oxidative stress, inflammation and apoptosis via targeting GIT1
Authors: Wenliang Song, Tiening Zhang, Ni Yang, Tao Zhang, Ri Wen, Chunfeng Liu
Journal: Bioengineered
PubMed ID: 34002676
Doi: 10.1080/21655979.2021.1926201
Products & Services: Mutagenesis Services   
Association between physical activity and immunogenicity of an inactivated virus vaccine against SARS-CoV-2 in patients with autoimmune rheumatic diseases
Authors: Bruno Gualano, Italo Ribeiro Lemes, Rafael Pires da Silva, Ana J Pinto, Bruna C Mazzolani, Fabiana I Smaira, Sofia M Sieczkowska, Nadia E Aikawa, Sandra G Pasoto, Ana C Medeiros-Ribeiro, Carla G S Saad, Emily F N Yuk, Clovis A Silva, Paul Swinton, Pedro C Hallal, Hamilton Roschel, Eloisa Bonfa
Journal: Brain Behav Immun
PubMed ID: 34954325
Doi: 10.1016/j.bbi.2021.12.016
Products & Services: Protein Reagents and Products   
ATP2, The essential P4-ATPase of malaria parasites, catalyzes lipid-stimulated ATP hydrolysis in complex with a Cdc50 β-subunit
Authors: Anaïs Lamy, Ewerton Macarini-Bruzaferro, Thibaud Dieudonné, Alex Perálvarez-Marín, Guillaume Lenoir, Cédric Montigny, Marc le Maire, José Luis Vázquez-Ibar
Journal: Emerg Microbes Infect
PubMed ID: 33372863
Doi: 10.1080/22221751.2020.1870413
Products & Services: Recombinant Proteins   
Antibody response to second dose of the BNT162b2 mRNA vaccine in the first 12 weeks in South Korea: A prospective longitudinal study
Authors: Hyun Jin Kim, Heon Jeong Yun, Jungok Kim, Sungmin Kym, Qute Choi
Journal: Vaccine
PubMed ID: 34953606
Doi: 10.1016/j.vaccine.2021.12.012
Products & Services: Protein Reagents and Products   
Mucosal immune response in BNT162b2 COVID-19 vaccine recipients
Authors: Lorenzo Azzi, Daniela Dalla Gasperina, Giovanni Veronesi, Mariam Shallak, Giuseppe Ietto, Domenico Iovino, Andreina Baj, Francesco Gianfagna, Vittorio Maurino, Daniele Focosi, Fabrizio Maggi, Marco Mario Ferrario, Francesco Dentali, Giulio Carcano, Angelo Tagliabue, Lorenzo Stefano Maffioli, Roberto Sergio Accolla, Greta Forlani
Journal: EBioMedicine
PubMed ID: 34954658
Doi: 10.1016/j.ebiom.2021.103788
Products & Services: Protein Reagents and Products   
Efficient discovery of potential inhibitors for SARS-CoV-2 3C-like protease from herbal extracts using a native MS-based affinity-selection method
Authors: Dafu Zhu, Haixia Su, Changqiang Ke, Chunping Tang, Matthias Witt, Ronald J Quinn, Yechun Xu, Jia Liu, Yang Ye
Journal: J Pharm Biomed Anal
PubMed ID: 34929567
Doi: 10.1016/j.jpba.2021.114538
Products & Services: Protein Reagents and Products   
Gene-specific quantification of nascent transcription following targeted degradation of endogenous proteins in cultured cells
Authors: Alissa D Guarnaccia, April M Weissmiller, William P Tansey
Journal: STAR Protoc
PubMed ID: 34917979
Doi: 10.1016/j.xpro.2021.101000
Products & Services: Codon Optimization   
Identification and validation of potential mRNA- microRNA- long-noncoding RNA (mRNA-miRNA-lncRNA) prognostic signature for cervical cancer
Authors: Jie Wang, Chen Zhang
Journal: Bioengineered
PubMed ID: 33682613
Doi: 10.1080/21655979.2021.1890377
Products & Services: Polyclonal Antibody Services   
Generation and utility of a single-chain fragment variable monoclonal antibody platform against a baculovirus expressed recombinant receptor binding domain of SARS-CoV-2 spike protein
Authors: Reda Salem, Alaa A El-Kholy, Fatma R Waly, Dalia Ayman, Aya Sakr, Mai Hussein
Journal: Mol Immunol
PubMed ID: 34915268
Doi: 10.1016/j.molimm.2021.12.006
Products & Services: Codon Optimization   
Deep mutational scanning for therapeutic antibody engineering
Authors: Kyrin R Hanning, Mason Minot, Annmaree K Warrender, William Kelton, Sai T Reddy
Journal: Trends Pharmacol Sci
PubMed ID: 34895944
Doi: 10.1016/j.tips.2021.11.010
Products & Services: Codon Optimization   
Sequential dynamics of virological and serological changes in the serum of SARS-CoV-2 infected patients
Authors: Serge Ouoba, Mafumi Okimoto, Shintaro Nagashima, Yoshihiro Kitahara, Kei Miwata, Ko Ko, Bunthen E, Aya Sugiyama, Kazuaki Takahashi, Takemasa Sakaguchi, Toshiro Takafuta, Junko Tanaka
Journal: J Med Virol
PubMed ID: 34897741
Doi: 10.1002/jmv.27518
Products & Services: Protein Reagents and Products   
A Pathogen-Inducible Rice NAC Transcription Factor ONAC096 Contributes to Immunity Against and pv by Direct Binding to the Promoters of , Magnaprothe oryzae, and Xanthomonas oryzaeoryzae OsRap26 OsWRKY62 OsPAL1
Authors: Hui Wang, Yan Bi, Yizhou Gao, Yuqing Yan, Xi Yuan, Xiaohui Xiong, Jiajing Wang, Jiayu Liang, Dayong Li, Fengming Song
Journal: Front Plant Sci
PubMed ID: 34956298
Doi: 10.3389/fpls.2021.802758
Products & Services: Catalog Peptides   
Novel sequential immunocapture microflow LC/MS/MS approach to measuring PTH-Fc protein in human serum
Authors: Haixing Wang, Jiang Wu, Peng Pan, Thuy Nguyen, Michael Cwik, Ling Morgan
Journal: Bioanalysis
PubMed ID: 34894717
Doi: 10.4155/bio-2021-0233
Products & Services: Codon Optimization   
Gastrin producing syngeneic mesenchymal stem cells protect non-obese diabetic mice from type 1 diabetes
Authors: Marie-Claude Gaudreau, Radhika R Gudi, Gongbo Li, Benjamin M Johnson, Chenthamarakshan Vasu
Journal: Autoimmunity
PubMed ID: 34882054
Doi: 10.1080/08916934.2021.2012165
Products & Services: Gene Synthesis   
Cryopreservation of network bioactivity and multi-lineage stromal cell differentiation potential within three-dimensional synthetic hydrogels
Authors:
Journal: Cryobiology
PubMed ID: 34922883
Doi: 10.1016/j.cryobiol.2021.12.003
Products & Services: Molecular Biology Reagents   
Structural Insight into the Mechanism of PALB2 Interaction with MRG15
Authors: Jennifer Redington, Jaigeeth Deveryshetty, Lakshmi Kanikkannan, Ian Miller, Sergey Korolev
Journal: Genes (Basel)
PubMed ID: 34946951
Doi: 10.3390/genes12122002
Products & Services: Mutant Libraries   
MiR-31 targets HSD17B14 and FSHR, and miR-20b targets HSD17B14 to affect apoptosis and steroid hormone metabolism of porcine ovarian granulosa cells
Authors: Siyuan Gao, Jing Zhao, Qinglei Xu, Yanli Guo, Mingzheng Liu, Chunlei Zhang, Allan P Schinckel, Bo Zhou
Journal: Theriogenology
PubMed ID: 34959084
Doi: 10.1016/j.theriogenology.2021.12.014
The impact of benzo[a]pyrene on murine allergic airway inflammation via epigenetic remodeling
Authors: Xihua Wang, Shuyuan Guan, Lingbin Sun, Zhongliang Dai
Journal: Environ Toxicol Pharmacol
PubMed ID: 34883242
Doi: 10.1016/j.etap.2021.103782
Adenovirus-mediated RNA interference against herpes simplex virus infection in vitro
Authors: Lin Chen, Zhi-Qiang Pan, Chang-Bin Zhai
Journal: Folia Histochem Cytobiol
PubMed ID: 34905214
Doi: 10.5603/FHC.a2021.0031
Products & Services: GenParts™ DNA Fragments   
Widely heterogeneous humoral and cellular immunity after mild SARS-CoV-2 infection in a homogeneous population of healthy young men
Authors: Nina Le Bert, Wan Ni Chia, Wei Yee Wan, Alvin Kuo Jing Teo, Samuel Zeng-Rong Chong, Nicole Tan, Doreen Soek Chin Tan, Adeline Chia, Iain Beehuat Tan, Kamini Kunasegaran, Qin Xuan Chua, Mohammad Yazid Abdad, Aven Shan Hua Ng, Shawn Vasoo, Julian Xiao-Li Ang, Mao Sheng Lee, Louisa Sun, Jinyan Fang, Feng Zhu, Alex R Cook, Tar Choon Aw, Jingxiang Huang, Clarence Tam, Fong Sin Lee, Hannah Clapham, Enan Jun-Kang Goh, Monica Socheata Suor Peou, Shiow Pin Tan, Siew Kim Ong, Lin-Fa Wang, Antonio Bertoletti, Li Yang Hsu, Biauw Chi Ong
Journal: Emerg Microbes Infect
PubMed ID: 34709140
Doi: 10.1080/22221751.2021.1999777
Convergent phenotypic evolution of rhodopsin for dim-light sensing across deep-diving vertebrates
Authors: Yu Xia , Yimeng Cui , Aishan Wang , Fangnan Liu , Hai Chi , Joshua H T Potter , Joseph Williamson , Xiaolan Chen , Stephen J Rossiter , Yang Liu
Journal: Mol Biol Evol
PubMed ID: 34463769
Doi: 10.1093/molbev/msab262
Products & Services: Catalog Peptides   
Nanopore-based measurement of the interaction of P450cam monooxygenase and putidaredoxin at the single-molecule level
Authors: Hui Chen, Yao Lin, Yi-Tao Long, Shelley D Minteer, Yi-Lun Ying
Journal: Faraday Discuss
PubMed ID: 34889330
Doi: 10.1039/d1fd00042j
Products & Services: Plasmid DNA Preparation   
Functional Characterization of Spinocerebellar Ataxia Associated Dynorphin A Mutant Peptides
Authors: Andreas Lieb, Germana Thaler, Barbara Fogli, Olga Trovato, Mitja Amon Posch, Teresa Kaserer, Luca Zangrandi
Journal: Biomedicines
PubMed ID: 34944698
Doi: 10.3390/biomedicines9121882
Products & Services: Catalog Peptides   
Synergistic enzyme cocktail between levansucrase and inulosucrase for superb levan-type fructooligosaccharide synthesis
Authors: Karan Wangpaiboon, Methus Klaewkla, Thanapon Charoenwongpaiboon, Napas Vongkusolkit, Pawinee Panpetch, Kamontip Kuttiyawong, Wonnop Visessanguan, Rath Pichyangkura
Journal: Enzyme Microb Technol
PubMed ID: 34923315
Doi: 10.1016/j.enzmictec.2021.109960
Modifications of IL-6 by Hypochlorous Acids: Effects on Receptor Binding
Authors: Lori I Robins, Erika K Keim, Deborah B Robins, John S Edgar, John S Meschke, Philip R Gafken, Jeffrey F Williams
Journal: ACS Omega
PubMed ID: 34984290
Doi: 10.1021/acsomega.1c05297
Products & Services: Gene Synthesis   
Rapid kinetics of calcium dissociation from plant calmodulin and calmodulin-like proteins and effect of target peptides
Authors: Francesca Troilo, Marco Pedretti, Carlo Travaglini-Allocatelli, Alessandra Astegno, Adele Di Matteo
Journal: Biochem Biophys Res Commun
PubMed ID: 34974297
Doi: 10.1016/j.bbrc.2021.12.077
Products & Services: Peptide Synthesis   
An engineered oncolytic vaccinia virus encoding a single-chain variable fragment against TIGIT induces effective antitumor immunity and synergizes with PD-1 or LAG-3 blockade
Authors: Shuguang Zuo, Min Wei, Tiancheng Xu, Lingkai Kong, Bohao He, Shiqun Wang, Shibing Wang, Junhua Wu, Jie Dong, Jiwu Wei
Journal: J Immunother Cancer
PubMed ID: 34949694
Doi: 10.1136/jitc-2021-002843
Products & Services: GenParts™ DNA Fragments   
Phosphodiesterase 8A Regulates CFTR Activity in Airway Epithelial Cells
Authors: Mark J Turner, Yukiko Sato, David Y Thomas, Kathy Abbott-Banner, John W Hanrahan
Journal: Cell Physiol Biochem
PubMed ID: 34936285
Doi: 10.33594/000000477
Phosphodiesterase 8A Regulates CFTR Activity in Airway Epithelial Cells
Authors: Mark J Turner, Yukiko Sato, David Y Thomas, Kathy Abbott-Banner, John W Hanrahan
Journal: Cell Physiol Biochem
PubMed ID: 34936285
Doi: 10.33594/000000477
COVID-19 mRNA booster vaccines elicit strong protection against SARS-CoV-2 Omicron variant in patients with cancer
Authors: Cong Zeng, John P Evans, Karthik Chakravarthy, Panke Qu, Sarah Reisinger, No-Joon Song, Mark P Rubinstein, Peter G Shields, Zihai Li, Shan-Lu Liu
Journal: Cancer Cell
PubMed ID: 34986328
Doi: 10.1016/j.ccell.2021.12.014
Products & Services: PCR Cloning and Subcloning   
A metabolic labeling protocol to enrich myristoylated proteins from
Authors: Xin Gong, Yanwen Feng, Hongyun Tang
Journal: STAR Protoc
PubMed ID: 34917984
Doi: 10.1016/j.xpro.2021.101013
BIX-01294 enhances the effect of chemotherapy on colorectal cancer by inhibiting the expression of stemness genes
Authors: Shikang Liu, Yihang Jiang, Hua Yang, Zhongke Hua, Yu Han, Cai Zhou, Shuling Xu, Shenglan Nie, Gaixia Xu, Xingsheng Shu, Xiaomei Wang
Journal: Biochem Biophys Res Commun
PubMed ID: 34979318
Doi: 10.1016/j.bbrc.2021.12.089
Products & Services: Recombinant Proteins   
Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2
Authors: Lihong Liu, Sho Iketani, Yicheng Guo, Jasper F-W Chan, Maple Wang, Liyuan Liu, Yang Luo, Hin Chu, Yiming Huang, Manoj S Nair, Jian Yu, Kenn K-H Chik, Terrence T-T Yuen, Chaemin Yoon, Kelvin K-W To, Honglin Chen, Michael T Yin, Magdalena E Sobieszczyk, Yaoxing Huang, Harris H Wang, Zizhang Sheng, Kwok-Yung Yuen, David D Ho
Journal: Nature
PubMed ID: 35016198
Doi: 10.1038/s41586-021-04388-0
Products & Services: Catalog Antibody   
A unique NLRC4 receptor from echinoderms mediates Vibrio phagocytosis via rearrangement of the cytoskeleton and polymerization of F-actin
Authors: Kaiyu Chen, Siyuan Zhang, Yina Shao, Ming Guo, Weiwei Zhang, Chenghua Li
Journal: PLoS Pathog
PubMed ID: 34898657
Doi: 10.1371/journal.ppat.1010145
Products & Services: Recombinant Antibody Expression   
A unique NLRC4 receptor from echinoderms mediates Vibrio phagocytosis via rearrangement of the cytoskeleton and polymerization of F-actin
Authors: Kaiyu Chen, Siyuan Zhang, Yina Shao, Ming Guo, Weiwei Zhang, Chenghua Li
Journal: PLoS Pathog
PubMed ID: 34898657
Doi: 10.1371/journal.ppat.1010145
Products & Services: Recombinant Antibody Expression   
Safety evaluation of the mouse TCRα - transduced T cell product in preclinical models in vivo and in vitro
Authors: Anastasiia Kalinina, Alexandra Bruter, Nadezhda Persiyantseva, Yulia Silaeva, Maria Zamkova, Ludmila Khromykh, Dmitry Kazansky
Journal: Biomed Pharmacother
PubMed ID: 34915667
Doi: 10.1016/j.biopha.2021.112480
Products & Services: Molecular Biology Reagents   
Comparison of SARS-CoV-2 Antibody Response 4 Weeks After Homologous vs Heterologous Third Vaccine Dose in Kidney Transplant Recipients: A Randomized Clinical Trial
Authors: Roman Reindl-Schwaighofer, Andreas Heinzel, Manuel Mayrdorfer, Rhea Jabbour, Thomas M Hofbauer, Anne Merrelaar, Michael Eder, Florina Regele, Konstantin Doberer, Paul Spechtl, Constantin Aschauer, Maximilian Koblischke, Christopher Paschen, Farsad Eskandary, Karin Hu, Barbara Öhler, Arshdeep Bhandal, Sabine Kleibenböck, Rahel I Jagoditsch, Bianca Reiskopf, Florian Heger, Gregor Bond, Georg A Böhmig, Robert Strassl, Lukas Weseslindtner, Alexander Indra, Judith H Aberle, Michael Binder, Rainer Oberbauer
Journal: JAMA Intern Med
PubMed ID: 34928302
Doi: 10.1001/jamainternmed.2021.7372
Products & Services: Protein Reagents and Products   
Bio inspired growth factor loaded self assembling peptide nano hydrogel for chronic wound healing
Authors: E Santhini, R Parthasarathy, M Shalini, S Dhivya, L Amalorpava Mary, V Vijaya Padma
Journal: Int J Biol Macromol
PubMed ID: 34920072
Doi: 10.1016/j.ijbiomac.2021.12.026
Products & Services: Catalog Antibody   
Induction of Th1 and Th2 in the protection against SARS-CoV-2 through mucosal delivery of an adenovirus vaccine expressing an engineered spike protein
Authors: Nai-Hsiang Chung, Ying-Chin Chen, Shiu-Ju Yang, Yu-Ching Lin, Horng-Yunn Dou, Lily Hui-Ching Wang, Ching-Len Liao, Yen-Hung Chow
Journal: Vaccine
PubMed ID: 34952759
Doi: 10.1016/j.vaccine.2021.12.024
Products & Services: Insect Expression   
SARS-CoV-2 recombinant proteins stimulate distinct cellular and humoral immune response profiles in samples from COVID-19 convalescent patients
Authors: Laís Teodoro da Silva, Marina Mazzilli Ortega, Bruna Tiaki Tiyo, Isabelle Freire Tabosa Viana, Tayná Evily de Lima, Tania Regina Tozetto-Mendoza, Luanda Mara da Silva Oliveira, Franciane Mouradian Emidio Teixeira, Roberto Dias Lins, Alexandre de Almeida, Maria Cassia Mendes-Correa, Alberto Jose da Silva Duarte, Telma Miyuki Oshiro
Journal: Clinics (Sao Paulo)
PubMed ID: 34878034
Doi: 10.6061/clinics/2021/e3548
Products & Services: Protein Reagents and Products   
Porcine Genome-Wide CRISPR Screen Identifies the Golgi Apparatus Complex Protein COG8 as a Pivotal Regulator of Influenza Virus Infection
Authors: Ao Zhou, Wenhua Zhang, Xia Dong, Bin Tang
Journal: CRISPR J
PubMed ID: 34935491
Doi: 10.1089/crispr.2021.0054
Products & Services: Oligo pool   
Anisotropic Rod-Shaped Particles Influence Injectable Granular Hydrogel Properties and Cell Invasion
Authors: Taimoor H Qazi, Jingyu Wu, Victoria G Muir, Shoshana Weintraub, Sarah E Gullbrand, Daeyeon Lee, David Issadore, Jason A Burdick
Journal: Adv Mater
PubMed ID: 34932833
Doi: 10.1002/adma.202109194
Products & Services: Peptide Synthesis   

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