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Synthetic Matrix Scaffolds Engineer the In Vivo Tumor Immune Microenvironment for Immunotherapy Screening

Authors: Meghan J O'Melia, Adriana Mulero-Russe, Jihoon Kim, Alyssa Pybus, Deborah DeRyckere, Levi Wood, Douglas K Graham, Edward Botchwey, Andrés J García, Susan N Thomas

Journal: Adv Mater

PubMed ID: 34989049

Doi: 10.1002/adma.202108084

Products & Services: Stable Cell Lines

Single-conformation spectroscopy of cold, protonated PG-containing peptides: switching β-turn types and formation of a sequential type II/II' double β-turn

Authors: John T Lawler, Christopher P Harrilal, Andrew F DeBlase, Edwin L Sibert, Scott A McLuckey, Timothy S Zwier

Journal: Phys Chem Chem Phys

PubMed ID: 35019911

Doi: 10.1039/d1cp04852j

Products & Services: Proteins, Expression, Isolation and Analysis

GRIM-19 is a target of mycobacterial Zn metalloprotease 1 and indispensable for NLRP3 inflammasome activation

Authors: Tomomi Kurane, Tetsuro Matsunaga, Tomoaki Ida, Kazuko Sawada, Akira Nishimura, Masayuki Fukui, Masayuki Umemura, Masaaki Nakayama, Naoya Ohara, Sohkichi Matsumoto, Takaaki Akaike, Goro Matsuzaki, Giichi Takaesu

Journal: FASEB J

PubMed ID: 34907600

Doi: 10.1096/fj.202101074RR

Products & Services: Codon Optimization

Efficacy of Convalescent Plasma to Treat Mild to Moderate COVID-19 in Kidney Transplant Patients: A Propensity Score Matching Analysis

Authors: Marina Pontello Cristelli, Dante Mário Langhi Junior, Laila Almeida Viana, Luis Gustavo Modelli de Andrade, Suelen Bianca Stopa Martins, Yasmim Cardoso Dreige, José Orlando Bordim, Helio Tedesco-Silva, José Medina-Pestana

Journal: Transplantation

PubMed ID: 34581314

Doi: 10.1097/TP.0000000000003962

Nucleic acid biomarkers to assess graft injury after liver transplantation

Authors: Elissa Bardhi, Jennifer McDaniels, Thomas Rousselle, Daniel G Maluf, Valeria R Mas

Journal: JHEP Rep

PubMed ID: 35243279

Doi: 10.1016/j.jhepr.2022.100439

Products & Services: Catalog Peptides

IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma

Authors: Suraya Elfrink, Martin Ter Beest, Luuk Janssen, Marijke Baltissen, Pascal Jansen, Angelique N Kenyon, Raymond Steen, Daynelys de Windt, Philipp Michael Hagemann, Corine Hess, Dick-Johan van Spronsen, Brigiet Hoevenaars, Ellen van der Spek, Zijun Y Xu-Monette, Ken H Young, Charlotte Kaffa, Sander Bervoets, Jolien van Heek, Eva Hesius, Charlotte M de Winde, Michiel Vermeulen, Michiel van den Brand, Blanca Scheijen, Annemiek van Spriel

Journal: Blood Adv

PubMed ID: 35086136

Doi: 10.1182/bloodadvances.2021004366

Products & Services: Plasmid DNA Preparation

The Role of Variants in Neurodevelopmental Diseases: Genotype-Phenotype Association

Authors: Li Shu, Neng Xiao, Jiong Qin, Qi Tian, Yanghui Zhang, Haoxian Li, Jing Liu, Qinrui Li, Weiyue Gu, Pengchao Wang, Hua Wang, Xiao Mao

Journal: Front Mol Neurosci

PubMed ID: 35095415

Doi: 10.3389/fnmol.2021.775479

Products & Services: Mammalian Expression

The protective effects of S14G-humanin (HNG) against mono-sodium urate (MSU) crystals- induced gouty arthritis

Authors: Jihui Zhang, Hongwei Lei, Xiu Li

Journal: Bioengineered

PubMed ID: 34965184

Doi: 10.1080/21655979.2021.2001911

Products & Services: Gene Synthesis

Ultrasound-Guided Microbubble-Mediated Locoregional Delivery of Multiple MicroRNAs Improves Chemotherapy in Hepatocellular Carcinoma

Authors: Huaijun Wang, Zhongqian Hu, Uday Kumar Sukumar, Rajendran Jc Bose, Arsenii Telichko, Jeremy J Dahl, Ramasamy Paulmurugan

Journal: Nanotheranostics

PubMed ID: 34976581

Doi: 10.7150/ntno.63320

Products & Services: Gene Synthesis

A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands

Authors: Micah Steffek, Elizabeth Helgason, Nataliya Popovych, Lionel Rougé, John M Bruning, Ke Sherry Li, Daniel J Burdick, Jianping Cai, Terry Crawford, Jing Xue, Willy Decurtins, Chunlin Fang, Felix Grubers, Michael J Holliday, Allyson Langley, Ann Petersen, Alexander Lee Satz, Aimin Song, Daniel Stoffler, Quentin Strebel, Jeffrey Y K Tom, Nicholas Skelton, Steven T Staben, Moreno Wichert, Melinda M Mulvihill, Erin C Dueber

Journal: Biochemistry

PubMed ID: 34985287

Doi: 10.1021/acs.biochem.1c00682

Products & Services: Gene Synthesis

Functional characterization of melanocortin-3 receptor in rainbow trout (Oncorhynchus mykiss)

Authors: Hui-Xia Yu, Yang Li, Wei-Jia Song, Hui Wang, Hao-Lin Mo, Qiao Liu, Xin-Miao Zhang, Ze-Bin Jiang, Li-Xin Wang

Journal: Fish Physiol Biochem

PubMed ID: 35098384

Doi: 10.1007/s10695-021-01033-5

Products & Services: Gene Synthesis

A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy

Authors: Audrey Champagne, Pallavi Jain, Lauriane Vélot, Julie Riopel, Véronique Lefebvre, Bertrand Neveu, Frédéric Pouliot

Journal: Theranostics

PubMed ID: 34976196

Doi: 10.7150/thno.63744

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Comparison of the immunogenicity of ChAdOx1 nCoV-19 vaccine against the wild-type and delta variants in kidney transplant recipients and healthy volunteers

Authors: Siriorn P Watcharananan, Peera Jaru-Ampornpan, Suree Sahawongcharoen, Nattakan Naitook, Orawan Himananto, Anan Jongkaewwattana, Chavachol Setthaudom, Sasivimol Rattanasiri, Angsana Phuphuakrat, Ammarin Thakkinstian, Viroon Mavichak

Journal: Am J Transplant

PubMed ID: 35090091

Doi: 10.1111/ajt.16966

Products & Services: Recombinant Antibody Expression

Comparison of the immunogenicity of ChAdOx1 nCoV-19 vaccine against the wild-type and delta variants in kidney transplant recipients and healthy volunteers

Journal: Am J Transplant

PubMed ID: 35090091

Doi: 10.1111/ajt.16966

Products & Services: Recombinant Antibody Expression

K-edge anomalous SAXS for protein solution structure modeling

Authors: Karman Virk, Kento Yonezawa, Komal Choukate, Lucky Singh, Nobutaka Shimizu, Barnali Chaudhuri

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35102886

Doi: 10.1107/S205979832101247X

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High level production of stable human serum albumin in Pichia pastoris and characterization of the recombinant product

Authors: Nitu Maity, Avijeet S Jaswal, Ashwani Gautam, Vikram Sahai, Saroj Mishra

Journal: Bioprocess Biosyst Eng

PubMed ID: 34999948

Doi: 10.1007/s00449-021-02670-z

Products & Services: PCR Cloning and Subcloning

Antibody response following SARS-CoV-2 vaccination among patients with type 2 diabetes mellitus: A systematic review

Authors: Nanny Natalia M Soetedjo, Maria Riastuti Iryaningrum, Sherly Lawrensia, Hikmat Permana

Journal: Diabetes Metab Syndr

PubMed ID: 35104750

Doi: 10.1016/j.dsx.2022.102406

Products & Services: Protein Reagents and Products

Exogenous Chemical Exposure Increased Transcription Levels of the Host Virus Receptor Involving Coronavirus Infection

Authors: Xiaoting Jin, Jingxu Zhang, Yanting Li, Ze Zhang, Tenglong Cui, Yuanyuan Wang, Linlin Yao, Xiaoxi Yang, Guangbo Qu, Yuxin Zheng, Guibin Jiang

Journal: Environ Sci Technol

PubMed ID: 35049283

Doi: 10.1021/acs.est.1c07172

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a Salmonella-based oral vaccine to control intestinal colonization of Shiga-toxin-producing Escherichia coli (STEC) in animals

Authors: Florencia Iannino, Paula J Uriza, Cecilia M Duarte, María V Pepe, Mara S Roset, Gabriel Briones

Journal: Vaccine

PubMed ID: 35086742

Doi: 10.1016/j.vaccine.2022.01.032

Products & Services: GenParts™ DNA Fragments

Lewis fucose is a key moiety for the recognition of histo-blood group antigens by GI9 norovirus, as revealed by structural analysis

Authors: Tomomi Kimura-Someya, Miyuki Kato-Murayama, Kazushige Katsura, Naoki Sakai, Kazutaka Murayama, Kazuharu Hanada, Mikako Shirouzu, Yuichi Someya

Journal: FEBS Open Bio

PubMed ID: 35038379

Doi: 10.1002/2211-5463.13370

Products & Services: GenParts™ DNA Fragments

Hybridization chain reaction circuit-based electrochemiluminescent biosensor for SARS-cov-2 RdRp gene assay

Authors: Kai Zhang, Zhenqiang Fan, Yue Huang, Yuedi Ding, Minhao Xie, Minghe Wang

Journal: Talanta

PubMed ID: 34998144

Doi: 10.1016/j.talanta.2022.123207

Products & Services: Gene Synthesis

Formation of Calprotectin-Derived Peptides in the Airways of Children with Cystic Fibrosis

Authors: Teagan S Edwards, Nina Dickerhof, Nicholas J Magon, Louise N Paton, Peter D Sly, Anthony J Kettle

Journal: J Immunol

PubMed ID: 35046105

Doi: 10.4049/jimmunol.2001017

Products & Services: Peptide Modifications

Characterization of male-biased fatty acid desaturase in the jewel wasp Nasonia vitripennis and its role in pheromone production

Authors: Jian-Qiu Cheng, Yu-Mei Tao, Jing Li, Yong-Zhuo Chen, Hao-Yuan Hu

Journal: J Exp Zool B Mol Dev Evol

PubMed ID: 34995007

Doi: 10.1002/jez.b.23120

Products & Services: Polyclonal Antibody Services

Identification, purification, and pharmacological activity analysis of Desmodus rotundus salivary plasminogen activator alpha1 (DSPAα1) expressed in transgenic rabbit mammary glands

Authors: Ting Zhang, Minya Zhou, Heqing Cai, Kunning Yan, Yiwen Zha, Wenwen Zhuang, Jingyan Liang, Yong Cheng

Journal: Transgenic Res

PubMed ID: 35034272

Doi: 10.1007/s11248-021-00292-5

Products & Services: Gene Synthesis

Production and application of mouse monoclonal antibodies targeting linear epitopes in pB602L of African swine fever virus

Authors: Pengfei Wang, Chunguo Liu, Shida Wang, Lili Wen, Zhibin Shi, Yue Chi, Ming Wang, Zaisi Liu, Zhenzhao Sun, Lili Wei, Decheng Yang, Xijun He, Jingfei Wang

Journal: Arch Virol

PubMed ID: 34984562

Doi: 10.1007/s00705-021-05335-0

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Survey of SARS-CoV-2 in dogs and cats in high-risk areas during the second wave of COVID-19 outbreak, Thailand

Authors: Waleemas Jairak, Kamonpan Charoenkul, Ekkapat Chamsai, Kitikhun Udom, Supassama Chaiyawong, Aphinya Hangsawek, Suchart Waenkaew, Anek Mungaomklang, Ratanaporn Tangwangvivat, Alongkorn Amonsin

Journal: Zoonoses Public Health

PubMed ID: 34981900

Doi: 10.1111/zph.12907

Comparative Immunogenicity of the Recombinant Receptor-Binding Domain of Protein S SARS-CoV-2 Obtained in Prokaryotic and Mammalian Expression Systems

Authors: Iuliia A Merkuleva, Dmitry N Shcherbakov, Mariya B Borgoyakova, Daniil V Shanshin, Andrey P Rudometov, Larisa I Karpenko, Svetlana V Belenkaya, Anastasiya A Isaeva, Valentina S Nesmeyanova, Elena I Kazachinskaia, Ekaterina A Volosnikova, Tatiana I Esina, Anna V Zaykovskaya, Oleg V Pyankov, Sophia S Borisevich, Arseniya A Shelemba, Anton N Chikaev, Alexander A Ilyichev

Journal: Vaccines (Basel)

PubMed ID: 35062757

Doi: 10.3390/vaccines10010096

Products & Services: Mammalian Expression

SMARCA4 biology in alveolar rhabdomyosarcoma

Authors: Narendra Bharathy, Megan M Cleary, Jin-Ah Kim, Kiyo Nagamori, Kenneth A Crawford, Eric Wang, Debarya Saha, Teagan P Settelmeyer, Reshma Purohit, Damianos Skopelitis, Kenneth Chang, Jessica A Doran, C Ward Kirschbaum, Suriya Bharathy, Davis W Crews, Matthew E Randolph, Anthony N Karnezis, Lisa Hudson-Price, Jyotsna Dhawan, Joel E Michalek, Alessio Ciulli, Christopher R Vakoc, Charles Keller

Journal: Oncogene

PubMed ID: 35094009

Doi: 10.1038/s41388-022-02205-0

Products & Services: Gene Synthesis

Immunogenic Properties of MVs Containing Structural Hantaviral Proteins: An Original Study

Authors: Layaly Shkair, Ekaterina Evgenevna Garanina, Ekaterina Vladimirovna Martynova, Alena Igorevna Kolesnikova, Svetlana Sergeevna Arkhipova, Angelina Andreevna Titova, Albert Anatolevich Rizvanov, Svetlana Francevna Khaiboullina

Journal: Pharmaceutics

PubMed ID: 35056989

Doi: 10.3390/pharmaceutics14010093

Products & Services: Plasmid DNA Preparation PCR Cloning and Subcloning

Horizontal gene transfer as a mechanism for the promiscuous acquisition of distinct classes of IRES by avian caliciviruses

Authors: Yani Arhab, Anna Miścicka, Tatyana V Pestova, Christopher U T Hellen

Journal: Nucleic Acids Res

PubMed ID: 34928389

Doi: 10.1093/nar/gkab1243

Products & Services: Gene Synthesis

A glutathione-independent DJ-1/PfpI domain-containing tomato glyoxalaseIII2, SlGLYIII2, confers enhanced tolerance under salt and osmotic stresses

Authors: Priya Gambhir, Vijendra Singh, Utkarsh Raghuvanshi, Adwaita Prasad Parida, Amit Pareek, Abhishek Roychowdhury, Sudhir K Sopory, Rahul Kumar, Arun Kumar Sharma

Journal: Plant Cell Environ

PubMed ID: 36377315

Doi: 10.1111/pce.14493

Products & Services: Proteins, Expression, Isolation and Analysis

Inhibition of the transcription factor ZNF281 by SUFU to suppress tumor cell migration

Authors: Yanran Deng, Dezhen Peng, Jing Xiao, Yunhe Zhao, Wenhao Ding, Shengtao Yuan, Li Sun, Jian Ding, Zizhang Zhou, Meixiao Zhan

Journal: Cell Death Differ

PubMed ID: 36220888

Doi: 10.1038/s41418-022-01073-1

Products & Services: Codon Optimization

Development of peptide affinity ligands for the purification of polyclonal and monoclonal Fabs from recombinant fluids

Authors: Ryan Kilgore, Wenning Chu, Dipendra Bhandari, David Fischler, Ruben G Carbonell, Michael Crapanzano, Stefano Menegatti

Journal: J Chromatogr A

PubMed ID: 36502645

Doi: 10.1016/j.chroma.2022.463701

Products & Services: Proteins, Expression, Isolation and Analysis

Modification of soy protein isolate using dielectric barrier discharge cold plasma assisted by modified atmosphere packaging

Authors: Qi Li, Fei Shen, Xueming He, Changrui Xing, Wenjing Yan, Yong Fang, Qiuhui Hu

Journal: Food Chem

PubMed ID: 36099827

Doi: 10.1016/j.foodchem.2022.134158

Products & Services: Proteins, Expression, Isolation and Analysis

Gel-Forming of Self-Assembling Peptides Functionalized with Food Bioactive Motifs Modulate DPP-IV and ACE Inhibitory Activity in Human Intestinal Caco-2 Cells

Authors: Raffaele Pugliese, Martina Bartolomei, Carlotta Bollati, Giovanna Boschin, Anna Arnoldi, Carmen Lammi

Journal: Biomedicines

PubMed ID: 35203539

Doi: 10.3390/biomedicines10020330

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A Bursaphelenchus xylophilus pathogenic protein Bx-FAR-1, as potential control target, mediates the jasmonic acid pathway in pines

Authors: Tong-Yue Wen, Xiao-Qin Wu, Jian-Ren Ye, Yi-Jun Qiu, Lin Rui, Yan Zhang

Journal: Pest Manag Sci

PubMed ID: 35060311

Doi: 10.1002/ps.6805

Products & Services: Recombinant Antibody Expression

The Role of CD147 in Pathological Cardiac Hypertrophy Is Regulated by Glycosylation

Authors: Fang-Yuan Zhong, Yi-Chao Zhao, Chen-Xu Zhao, Zhi-Chun Gu, Xi-Yuan Lu, Wen-Long Jiang, Ling-Chen Gao, Wen-Li Li, Zi-Han Qin, Heng Ge, Jun Pu

Journal: Oxid Med Cell Longev

PubMed ID: 35096272

Doi: 10.1155/2022/6603296

Products & Services: Proteins, Expression, Isolation and Analysis

Exploring the underlying mechanisms on NaCl-induced reduction in digestibility of myoglobin

Authors: Hui Liu, Qian Li, Shuai Jiang, Miao Zhang, Di Zhao, Kai Shan, Chunbao Li

Journal: Food Chem

PubMed ID: 35077987

Doi: 10.1016/j.foodchem.2022.132183

Products & Services: Proteins, Expression, Isolation and Analysis

Introducing an Artificial Deazaflavin Cofactor in and

Authors: Misun Lee, Jeroen Drenth, Milos Trajkovic, René M de Jong, Marco W Fraaije

Journal: ACS Synth Biol

PubMed ID: 35044755

Doi: 10.1021/acssynbio.1c00552

Products & Services: Bacterial Expression

Expression, Purification, and Biophysical Characterization of Klebsiella Pneumoniae Nicotinate Nucleotide Adenylyltransferase

Authors: Tasvi Daya, Olamide Jeje, Reabetswe Maake, Chinyere Aloke, Thandeka Khoza, Ikechukwu Achilonu

Journal: Protein J

PubMed ID: 35083643

Doi: 10.1007/s10930-021-10037-2

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The H, N and C resonance assignments of the low-complexity domain from the oncogenic fusion protein EWS-FLI1

Authors: Courtney N Johnson, Xiaoping Xu, Stephen P Holloway, David S Libich

Journal: Biomol NMR Assign

PubMed ID: 34994941

Doi: 10.1007/s12104-021-10061-4

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Hemagglutinin-based DNA vaccines containing trimeric self-assembling nanoparticles confer protection against influenza

Authors: Yongbo Qiao, Shenghui Jin, Jiaojiao Nie, Yaotian Chang, Bo Wang, Shanshan Guan, Qinghan Li, Yuhua Shi, Wei Kong, Yaming Shan

Journal: J Leukoc Biol

PubMed ID: 35040188

Doi: 10.1002/JLB.6A1021-535R

Products & Services: Mammalian Expression

lnc-MRGPRF-6:1 Promotes M1 Polarization of Macrophage and Inflammatory Response through the TLR4-MyD88-MAPK Pathway

Authors: Dan Hu, Yuzhong Wang, Zhihuan You, Yingfei Lu, Caihong Liang

Journal: Mediators Inflamm

PubMed ID: 35125964

Doi: 10.1155/2022/6979117

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Anti-Coagulant and Antimicrobial Recombinant Heparin-Binding Major Ampullate Spidroin 2 (MaSp2) Silk Protein

Authors: Pranothi Mulinti, Dorina Diekjürgen, Kristen Kurtzeborn, Narayanaganesh Balasubramanian, Shane J Stafslien, David W Grainger, Amanda E Brooks

Journal: Bioengineering (Basel)

PubMed ID: 35200400

Doi: 10.3390/bioengineering9020046

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Anti-Coagulant and Antimicrobial Recombinant Heparin-Binding Major Ampullate Spidroin 2 (MaSp2) Silk Protein

Authors: Pranothi Mulinti, Dorina Diekjürgen, Kristen Kurtzeborn, Narayanaganesh Balasubramanian, Shane J Stafslien, David W Grainger, Amanda E Brooks

Journal: Bioengineering (Basel)

PubMed ID: 35200400

Doi: 10.3390/bioengineering9020046

Products & Services: Gene Synthesis

Alpha-Soluble NSF Attachment Protein Prevents the Cleavage of the SARS-CoV-2 Spike Protein by Functioning as an Interferon-Upregulated Furin Inhibitor

Authors: Jinliang Wang, Jie Luo, Zhiyuan Wen, Xinxin Wang, Lei Shuai, Gongxun Zhong, Chong Wang, Ziruo Sun, Weiye Chen, Jinying Ge, Renqiang Liu, Xijun Wang, Zhigao Bu

Journal: MBio

PubMed ID: 35012335

Doi: 10.1128/mbio.02443-21

Products & Services: Proteins, Expression, Isolation and Analysis

Anti-aquaporin-4 immunoglobulin G colorimetric detection by silver nanoparticles

Authors: Akemi M Higa, Ariana S Moraes, Flávio M Shimizu, Raquel G Bueno, Luís A Peroni, Francisco T Strixino, Nise A C Sousa, Elenice Deffune, Ana Lívia C Bovolato, Osvaldo N Oliveira, Doralina G Brum, Fabio L Leite

Journal: Nanomedicine

PubMed ID: 35114406

Doi: 10.1016/j.nano.2022.102531

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Genome-wide identification and expression pattern analysis of the TCP transcription factor family in

Authors: Li Yu, Qiangwen Chen, Jiarui Zheng, Feng Xu, Jiabao Ye, Weiwei Zhang, Yongling Liao, Xiaoyan Yang

Journal: Plant Signal Behav

PubMed ID: 35068346

Doi: 10.1080/15592324.2021.1994248

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Oral subunit SARS-CoV-2 vaccine induces systemic neutralizing IgG, IgA and cellular immune responses and can boost neutralizing antibody responses primed by an injected vaccine

Authors: Jacob Pitcovski, Nady Gruzdev, Anna Abzach, Chen Katz, Ran Ben-Adiva, Michal Brand-Shwartz, Itamar Yadid, Einav Ratzon-Ashkenazi, Ken Emquies, Hadasa Israeli, Hadar Haviv, Irena Rapoport, Itai Bloch, Roy Shadmon, Zohar Eitan, Dalia Eliahu, Talia Hilel, Morris Laster, Sigal Kremer-Tal, Tamara Byk-Tennenbaum, Ehud Shahar

Journal: Vaccine

PubMed ID: 35078662

Doi: 10.1016/j.vaccine.2022.01.025

Products & Services: Proteins, Expression, Isolation and Analysis

Transport Turnover Rates for Human OCT2 and MATE1 Expressed in Chinese Hamster Ovary Cells

Authors: Xiaohong Zhang, Stephen H Wright

Journal: Int J Mol Sci

PubMed ID: 35163393

Doi: 10.3390/ijms23031472

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