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Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity

Authors: Dapeng Li, Simon Brackenridge, Lucy C Walters, Olivia Swanson, Karl Harlos, Daniel Rozbesky, Derek W Cain, Kevin Wiehe, Richard M Scearce, Maggie Barr, Zekun Mu, Robert Parks, Max Quastel, Robert J Edwards, Yunfei Wang, Wes Rountree, Kevin O Saunders, Guido Ferrari, Persephone Borrow, E Yvonne Jones, S Munir Alam, Mihai L Azoitei, Geraldine M Gillespie, Andrew J McMichael, Barton F Haynes

Journal: Commun Biol

PubMed ID: 35347236

Doi: 10.1038/s42003-022-03183-5

Products & Services: Mammalian Expression

RPA-Cas12aDS: A visual and fast molecular diagnostics platform based on RPA-CRISPR-Cas12a method for infectious bursal disease virus detection

Authors: Su-Ya Zheng, Li-Li Ma, Xiao-Li Wang, Li-Xin Lu, Sun-Ting Ma, Bin Xu, Wei Ouyang

Journal: J Virol Methods

PubMed ID: 35288230

Doi: 10.1016/j.jviromet.2022.114523

Products & Services: Plasmid DNA Preparation

Targeted Codelivery of Prodigiosin and Simvastatin Using Smart BioMOF: Functionalization by Recombinant Anti-VEGFR1 scFv

Authors: Somayyeh Mirzaeinia, Sedighe Zeinali, Nediljko Budisa, Hamid Reza Karbalaei-Heidari

Journal: Front Bioeng Biotechnol

PubMed ID: 35402395

Doi: 10.3389/fbioe.2022.866275

Products & Services: Gene Synthesis

Production of indole by Corynebacterium glutamicum microbial cell factories for flavor and fragrance applications

Authors: Melanie Mindt, Arman Beyraghdar Kashkooli, Maria Suarez-Diez, Lenny Ferrer, Tatjana Jilg, Dirk Bosch, Vitor Martins Dos Santos, Volker F Wendisch, Katarina Cankar

Journal: Microb Cell Fact

PubMed ID: 35331232

Doi: 10.1186/s12934-022-01771-y

Products & Services: Bacterial Expression

A Single Amino Acid Residue Defines the Difference in NLRP3 Inflammasome Activation between NEK7 and NEK6

Authors: Devon Jeltema, Jihong Wang, Juan Cai, Nathan Kelley, Zhe Yang, Yuan He

Journal: J Immunol

PubMed ID: 35354613

Doi: 10.4049/jimmunol.2101154

Products & Services: Gene Synthesis

Phosphoproteome Analysis Identifies a Synaptotagmin-1-Associated Complex Involved in Ischemic Neuron Injury

Authors: Wei Jiang, Pei Zhang, Peng Yang, Na Kang, Junqiang Liu, Yilixiati Aihemaiti, Haijun Tu

Journal: Mol Cell Proteomics

PubMed ID: 35257887

Doi: 10.1016/j.mcpro.2022.100222

Products & Services: Peptide Synthesis

Computational Design and Biological Evaluation of Analogs of Lupin Peptide P5 Endowed with Dual PCSK9/HMG-CoAR Inhibiting Activity

Authors: Carmen Lammi, Enrico M A Fassi, Jianqiang Li, Martina Bartolomei, Giulia Benigno, Gabriella Roda, Anna Arnoldi, Giovanni Grazioso

Journal: Pharmaceutics

PubMed ID: 35336039

Doi: 10.3390/pharmaceutics14030665

Products & Services: Protein and Antibody Isolation

Development of spirulina for the manufacture and oral delivery of protein therapeutics

Authors: Benjamin W Jester, Hui Zhao, Mesfin Gewe, Thomas Adame, Lisa Perruzza, David T Bolick, Jan Agosti, Nhi Khuong, Rolf Kuestner, Caitlin Gamble, Kendra Cruickshank, Jeremy Ferrara, Rachelle Lim, Troy Paddock, Colin Brady, Stacey Ertel, Miaohua Zhang, Alex Pollock, Jamie Lee, Jian Xiong, Michael Tasch, Tracy Saveria, David Doughty, Jacob Marshall, Damian Carrieri, Lauren Goetsch, Jason Dang, Nathaniel Sanjaya, David Fletcher, Anissa Martinez, Bryce Kadis, Kristjan Sigmar, Esha Afreen, Tammy Nguyen, Amanda Randolph, Alexandria Taber, Ashley Krzeszowski, Brittney Robinett, David B Volkin, Fabio Grassi, Richard Guerrant, Ryo Takeuchi, Brian Finrow, Craig Behnke, James Roberts

Journal: Nat Biotechnol

PubMed ID: 35314813

Doi: 10.1038/s41587-022-01249-7

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Efficacy and Safety of Heterologous Booster Vaccination after Ad5-nCoV (CanSino Biologics) Vaccine: A Preliminary Descriptive Study

Authors: José Francisco Muñoz-Valle, Gabriela Athziri Sánchez-Zuno, Mónica Guadalupe Matuz-Flores, Cristian Oswaldo Hernández-Ramírez, Saúl Alberto Díaz-Pérez, Christian Johana Baños-Hernández, Francisco Javier Turrubiates-Hernández, Alejandra Natali Vega-Magaña, Jorge Hernández-Bello

Journal: Vaccines (Basel)

PubMed ID: 35335032

Doi: 10.3390/vaccines10030400

Spectrum of Phenotypic, Genetic, and Functional Characteristics in Patients With Epilepsy With Pathogenic Variants

Authors: Niklas Schwarz, Simone Seiffert, Manuela Pendziwiat, Annika Verena Rademacher, Tobias Brünger, Ulrike B S Hedrich, Paul B Augustijn, Hartmut Baier, Allan Bayat, Francesca Bisulli, Russell J Buono, Ben Zeev Bruria, Michael G Doyle, Renzo Guerrini, Gali Heimer, Michele Iacomino, Hugh Kearney, Karl Martin Klein, Ioanna Kousiappa, Wolfram S Kunz, Holger Lerche, Laura Licchetta, Ebba Lohmann, Raffaella Minardi, Marie McDonald, Sarah Montgomery, Lejla Mulahasanovic, Renske Oegema, Barel Ortal, Savvas S Papacostas, Francesca Ragona, Tiziana Granata, Phillip S Reif, Felix Rosenow, Annick Rothschild, Paolo Scudieri, Pasquale Striano, Paolo Tinuper, George A Tanteles, Annalisa Vetro, Felix Zahnert, Ethan M Goldberg, Federico Zara, Dennis Lal, Patrick May, Hiltrud Muhle, Ingo Helbig, Yvonne Weber

Journal: Neurology

PubMed ID: 35314505

Doi: 10.1212/WNL.0000000000200660

Products & Services: Protein and Antibody Isolation

Site-specific nanobody-oligonucleotide conjugation for super-resolution imaging

Authors: Laura Teodori, Marjan Omer, Anders Märcher, Mads K Skaanning, Veronica L Andersen, Jesper S Nielsen, Emil Oldenburg, Yuchen Lin, Kurt V Gothelf, Jørgen Kjems

Journal: J Biol Methods

PubMed ID: 35510035

Doi: 10.14440/jbm.2022.381

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Imprinted SARS-CoV-2-specific memory lymphocytes define hybrid immunity

Authors: Lauren B Rodda, Peter A Morawski, Kurt B Pruner, Mitchell L Fahning, Christian A Howard, Nicholas Franko, Jennifer Logue, Julie Eggenberger, Caleb Stokes, Inah Golez, Malika Hale, Michael Gale, Helen Y Chu, Daniel J Campbell, Marion Pepper

Journal: Cell

PubMed ID: 35413241

Doi: 10.1016/j.cell.2022.03.018

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Complement C3a Enhances the Phagocytic Activity of B Cells Through C3aR in a Fish

Authors: Zi-You Ma, Jia-Xin Liang, Wen-Shuo Li, Yuan Sun, Chang-Song Wu, Ya-Zhen Hu, Jun Li, Yong-An Zhang, Xu-Jie Zhang

Journal: Front Immunol

PubMed ID: 35386704

Doi: 10.3389/fimmu.2022.873982

Products & Services: Protein and Antibody Isolation

Therapeutic Effect of Melittin-dKLA Targeting Tumor-Associated Macrophages in Melanoma

Authors: Ik-Hwan Han, Chanmi Jeong, Juwon Yang, Seung-Hyeok Park, Deok-Sang Hwang, Hyunsu Bae

Journal: Int J Mol Sci

PubMed ID: 35328518

Doi: 10.3390/ijms23063094

Products & Services: Chemicals

Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling

Authors: Kim van Kuijk, Jasper A F Demandt, Javier Perales-Patón, Thomas L Theelen, Christoph Kuppe, Elke Marsch, Jenny de Bruijn, Han Jin, Marion J Gijbels, Ljubica Matic, Barend M E Mees, Chris P M Reutelingsperger, Ulf Hedin, Erik A L Biessen, Peter Carmeliet, Andrew H Baker, Rafael K Kramann, Leon J Schurgers, Julio Saez-Rodriguez, Judith C Sluimer

Journal: Cardiovasc Res

PubMed ID: 33913468

Doi: 10.1093/cvr/cvab152

Products & Services: Protein and Antibody Isolation

Injectable Slow-Release Hydrogel Formulation of a Plant Virus-Based COVID-19 Vaccine Candidate

Authors: Christian Isalomboto Nkanga, Oscar A Ortega-Rivera, Matthew D Shin, Miguel A Moreno-Gonzalez, Nicole F Steinmetz

Journal: Biomacromolecules

PubMed ID: 35344365

Doi: 10.1021/acs.biomac.2c00112

Products & Services: Recombinant Proteins

MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity

Authors: Thilini S Munasinghe, Megan R Edwards, Sofiya Tsimbalyuk, Olivia A Vogel, Kate M Smith, Murray Stewart, Justin K Foster, Loretta A Bosence, David Aragão, Justin A Roby, Christopher F Basler, Jade K Forwood

Journal: Nat Commun

PubMed ID: 35338144

Doi: 10.1038/s41467-022-28851-2

Products & Services: Bacterial Expression

Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer

Authors: Andrea Lopez, Denis E Reyna, Nadege Gitego, Felix Kopp, Hua Zhou, Miguel A Miranda-Roman, Lars Ulrik Nordstrøm, Swathi-Rao Narayanagari, Ping Chi, Eduardo Vilar, Aristotelis Tsirigos, Evripidis Gavathiotis

Journal: Nat Commun

PubMed ID: 35256598

Doi: 10.1038/s41467-022-28741-7

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The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal β-hairpin and induces neutrophil migration as a selective CXCR2 agonist

Authors: Christian Berg, Michael J Wedemeyer, Motiejus Melynis, Roman R Schlimgen, Lasse H Hansen, Jon Våbenø, Francis C Peterson, Brian F Volkman, Mette M Rosenkilde, Hans R Lüttichau

Journal: PLoS Pathog

PubMed ID: 35271688

Doi: 10.1371/journal.ppat.1010355

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Diagnostic Host Gene Expression Analysis by Quantitative Reverse Transcription Loop-Mediated Isothermal Amplification to Discriminate between Bacterial and Viral Infections

Authors: Melissa C Remmel, Sabrina M Coyle, Mark W Eshoo, Timothy E Sweeney, David C Rawling

Journal: Clin Chem

PubMed ID: 35134876

Doi: 10.1093/clinchem/hvab275

Products & Services: Mammalian Expression

Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization

Authors: Edward A Partlow, Kevin S Cannon, Gunther Hollopeter, Richard W Baker

Journal: Nat Struct Mol Biol

PubMed ID: 35347313

Doi: 10.1038/s41594-022-00749-z

Products & Services: Peptide Synthesis

Zymomonas mobilis ZM4 Utilizes an NADP-Dependent Acetaldehyde Dehydrogenase To Produce Acetate

Authors: Magdalena M Felczak, Michaela A TerAvest

Journal: J Bacteriol

PubMed ID: 35258321

Doi: 10.1128/jb.00563-21

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A simple reverse genetics method to generate recombinant coronaviruses

Authors: Julien Mélade, Géraldine Piorkowski, Franck Touret, Toscane Fourié, Jean-Sélim Driouich, Maxime Cochin, Hawa Sophia Bouzidi, Bruno Coutard, Antoine Nougairède, Xavier de Lamballerie

Journal: EMBO Rep

PubMed ID: 35239997

Doi: 10.15252/embr.202153820

Products & Services: Gene Fragments

Regulation of paternal 5mC oxidation and H3K9me2 asymmetry by ERK1/2 in mouse zygotes

Authors: Baobao Chen, Mingtian Deng, Meng-Hao Pan, Shao-Chen Sun, Honglin Liu

Journal: Cell Biosci

PubMed ID: 35255956

Doi: 10.1186/s13578-022-00758-x

Products & Services: Protein and Antibody Isolation

RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin

Authors: Tal Keren-Kaplan, Amra Sarić, Saikat Ghosh, Chad D Williamson, Rui Jia, Yan Li, Juan S Bonifacino

Journal: Nat Commun

PubMed ID: 35314674

Doi: 10.1038/s41467-022-28952-y

Products & Services: Plasmid DNA Preparation

Circ_0060531 knockdown ameliorates IL-22-induced keratinocyte damage by binding to miR-330-5p to decrease GAB1 expression

Authors: Quan Shi, Jing Luo, Weiming Chen, Qi He, Jianwen Long, Bo Zhang

Journal: Autoimmunity

PubMed ID: 35293807

Doi: 10.1080/08916934.2022.2037127

Products & Services: Mutant Libraries

A peroxisomal heterodimeric enzyme is involved in benzaldehyde synthesis in plants

Authors: Xing-Qi Huang, Renqiuguo Li, Jianxin Fu, Natalia Dudareva

Journal: Nat Commun

PubMed ID: 35292635

Doi: 10.1038/s41467-022-28978-2

Products & Services: Codon Optimization

Age-dependent formation of TMEM106B amyloid filaments in human brains

Authors: Manuel Schweighauser, Diana Arseni, Mehtap Bacioglu, Melissa Huang, Sofia Lövestam, Yang Shi, Yang Yang, Wenjuan Zhang, Abhay Kotecha, Holly J Garringer, Ruben Vidal, Grace I Hallinan, Kathy L Newell, Airi Tarutani, Shigeo Murayama, Masayuki Miyazaki, Yuko Saito, Mari Yoshida, Kazuko Hasegawa, Tammaryn Lashley, Tamas Revesz, Gabor G Kovacs, John van Swieten, Masaki Takao, Masato Hasegawa, Bernardino Ghetti, Maria Grazia Spillantini, Benjamin Ryskeldi-Falcon, Alexey G Murzin, Michel Goedert, Sjors H W Scheres

Journal: Nature

PubMed ID: 35344985

Doi: 10.1038/s41586-022-04650-z

Products & Services: Gene Fragments

Degenerate sequence-based CRISPR diagnostic for Crimean-Congo hemorrhagic fever virus

Authors: Hongzhao Li, Alexander Bello, Greg Smith, Dominic M S Kielich, James E Strong, Bradley S Pickering

Journal: PLoS Negl Trop Dis

PubMed ID: 35271569

Doi: 10.1371/journal.pntd.0010285

Products & Services: PCR Cloning and Subcloning

The vaccinia-based Sementis Copenhagen Vector coronavirus disease 2019 vaccine induces broad and durable cellular and humoral immune responses

Authors: Preethi Eldi, Tamara H Cooper, Natalie A Prow, Liang Liu, Gary K Heinemann, Voueleng J Zhang, Abigail D Trinidad, Ruth Marian Guzman-Genuino, Peter Wulff, Leanne M Hobbs, Kerrilyn R Diener, John D Hayball

Journal: Immunol Cell Biol

PubMed ID: 35188985

Doi: 10.1111/imcb.12539

Products & Services: Protein and Antibody Isolation

Alpha-hydroxytropolones are noncompetitive inhibitors of human RNase H1 that bind to the active site and modulate substrate binding

Authors: Nathan L Ponzar, Razia Tajwar, Nicola Pozzi, John E Tavis

Journal: J Biol Chem

PubMed ID: 35247386

Doi: 10.1016/j.jbc.2022.101790

Products & Services: Mutagenesis Services

YfiB: An Outer Membrane Protein Involved in the Virulence of

Authors: Tanuka Sen, Naresh K Verma

Journal: Microorganisms

PubMed ID: 35336228

Doi: 10.3390/microorganisms10030653

Products & Services: Mutant Libraries

Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold

Authors: Jingjing Chen, Huixin He, Aihuan Wei, Yalei Li, Gang Cheng, Hui Qin, Hanyue Zhong, Hongchun Liu, Meiyu Geng, Aijun Shen, Youhong Hu

Journal: Eur J Med Chem

PubMed ID: 35395439

Doi: 10.1016/j.ejmech.2022.114259

Products & Services: Protein Electrophoresis and Western

Convergent epitope specificities, V gene usage and public clones elicited by primary exposure to SARS-CoV-2 variants

Authors: Noemia S Lima, Maryam Mukhamedova, Timothy S Johnston, Danielle A Wagner, Amy R Henry, Lingshu Wang, Eun Sung Yang, Yi Zhang, Kevina Birungi, Walker P Black, Sijy O'Dell, Stephen D Schmidt, Damee Moon, Cynthia G Lorang, Bingchun Zhao, Man Chen, Kristin L Boswell, Jesmine Roberts-Torres, Rachel L Davis, Lowrey Peyton, Sandeep R Narpala, Sarah O'Connell, Jennifer Wang, Alexander Schrager, Chloe Adrienna Talana, Kwanyee Leung, Wei Shi, Rawan Khashab, Asaf Biber, Tal Zilberman, Joshua Rhein, Sara Vetter, Afeefa Ahmed, Laura Novik, Alicia Widge, Ingelise Gordon, Mercy Guech, I-Ting Teng, Emily Phung, Tracy J Ruckwardt, Amarendra Pegu, John Misasi, Nicole A Doria-Rose, Martin Gaudinski, Richard A Koup, Peter D Kwong, Adrian B McDermott, Sharon Amit, Timothy W Schacker, Itzchak Levy, John R Mascola, Nancy J Sullivan, Chaim A Schramm, Daniel C Douek

Journal: biorxiv

PubMed ID: 35378757

Doi: 10.1101/2022.03.28.486152

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Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate

Authors: Ruixue Wang, Saori Suzuki, Johnathan D Guest, Brigitte Heller, Maricar Almeda, Alexander K Andrianov, Alexander Marin, Roy A Mariuzza, Zhen-Yong Keck, Steven K H Foung, Abdul S Yunus, Brian G Pierce, Eric A Toth, Alexander Ploss, Thomas R Fuerst

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35263223

Doi: 10.1073/pnas.2112008119

Products & Services: PCR Cloning and Subcloning

Rapid Exchange of Stably Bound Protein and DNA Cargo on a DNA Origami Receptor

Authors: James W P Brown, Rokiah G Alford, James C Walsh, Richard E Spinney, Stephanie Y Xu, Sophie Hertel, Jonathan F Berengut, Lisanne M Spenkelink, Antoine M van Oijen, Till Böcking, Richard G Morris, Lawrence K Lee

Journal: ACS Nano

PubMed ID: 35316035

Doi: 10.1021/acsnano.2c00699

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In situ solid-state NMR study of antimicrobial peptide interactions with erythrocyte membranes

Authors: Kiran Kumar, Mathew Sebastiao, Alexandre A Arnold, Steve Bourgault, Dror E Warschawski, Isabelle Marcotte

Journal: Biophys J

PubMed ID: 35278426

Doi: 10.1016/j.bpj.2022.03.009

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Coupling cell growth and biochemical pathway induction in Saccharomyces cerevisiae for production of (+)-valencene and its chemical conversion to (+)-nootkatone

Authors: Ziling Ye, Yanglei Huang, Bin Shi, Zilei Xiang, Zhu Tian, Man Huang, Liangliang Wu, Zixin Deng, Kun Shen, Tiangang Liu

Journal: Metab Eng

PubMed ID: 35296429

Doi: 10.1016/j.ymben.2022.03.005

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Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH

Authors: Alena Stsiapanava, Chenrui Xu, Shunsuke Nishio, Ling Han, Nao Yamakawa, Marta Carroni, Kathryn Tunyasuvunakool, John Jumper, Daniele de Sanctis, Bin Wu, Luca Jovine

Journal: Nat Struct Mol Biol

PubMed ID: 35273390

Doi: 10.1038/s41594-022-00729-3

Products & Services: Mutant Libraries

Targeting ferroptosis suppresses osteocyte glucolipotoxicity and alleviates diabetic osteoporosis

Authors: Yiqi Yang , Yixuan Lin , Minqi Wang , Kai Yuan , Qishan Wang , Pei Mu , Jingke Du , Zhifeng Yu , Shengbing Yang ， Kai Huang , Yugang Wang , Hanjun Li , Tingting Tang

Journal: Bone Res

PubMed ID: 35260560

Doi: doi.org/10.1038/s41413-022-00198-w

Products & Services: Protein Electrophoresis and Western

DNA immunotherapy targeting BARF1 induces potent anti-tumor responses against Epstein-Barr-virus-associated carcinomas

Authors: Xizhou Zhu, Alfredo Perales-Puchalt, Krzysztof Wojtak, Ziyang Xu, Kun Yun, Pratik S Bhojnagarwala , Devivasha Bordoloi , Daniel H Park, Kevin Liaw, Mamadou A Bah, Paul M Lieberman , Ebony N Gary , Ami Patel , David B Weiner

Journal: Mol Ther Oncolytics

PubMed ID: 35071745

Doi: 10.1016/j.omto.2021.12.017

Products & Services: Plasmid DNA Preparation Peptide Synthesis

RNF115 Inhibits the Post-ER Trafficking ofTLRs and TLRs-Mediated Immune Responses by Catalyzing K11-Linked Ubiquitination ofRAB1A and RAB13

Authors: Zhi-Dong Zhang , Hong-Xu Li , Hu Gan , Zhen Tang , Yu-Yao Guo , Shu-Qi Yao , Tianzi Liuyu , Bo Zhong , Dandan Lin

Journal: Adv Sci (Weinh)

PubMed ID: 35343654

Doi: doi.org/10.1002/advs.202105391

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SARS-CoV-2 variant B.1.1.7 caused HLA-A2 CD8 T cell epitope mutations for impaired cellular immune response.

Authors: Chanchan Xiao, Lipeng Mao , Zhigang Wang , Lijuan Gao , Guodong Zhu , Jun Su , Xiongfei Chen , Jun Yuan , Yutian Hu, Zhinan Yin, Jun Xie , Weiqing Ji , Haitao Niu , Feng Gao, Oscar Junhong Luo , Lianbo Xiao , Pengcheng Wang , Guobing Chen

Journal: iScience

PubMed ID: 35194575

Doi: 10.1016/j.isci.2022.103934

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TFPIisacoloniccryptreceptorforTcdBfromhypervirulentclade2C.difficile

Authors: Jianhua Luo , Qi Yang , Xiaofeng Zhang , Yuanyuan Zhang , Li Wan , Xiechao Zhan , Yao Zhou , Liuqing He , Danyang Li , Dazhi Jin , Ying Zhen , Jing Huang , Yanyan Li , Liang Tao

Journal: Cell

PubMed ID: 35303428

Doi: 10.1016/j.cell.2022.02.010

Products & Services: Codon Optimization

Small molecule targeting CELF1 RNA-binding activity to control HSC activation and liver fibrosis

Authors: Yang Tan, Xueqing Sun, Yizhu Xu, Bingjie Tang, Shuaiqi Xu, Dong Lu, Yan Ye, Xiaomin Luo, Xu Diao, Fulong Li, Tianyi Wang, Jiayu Chen, Qiang Xu, Xingxin Wu

Journal: Nucleic Acids Res

PubMed ID: 35234905

Doi: 10.1093/nar/gkac139

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Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors

Authors: Jia Duan , Dan-Dan Shen , Tingting Zhao , Shimeng Guo , Xinheng He , Wanchao Yin , Peiyu Xu , Yujie Ji , Li-Nan Chen , Jinyu Liu , Huibing Zhang , Qiufeng Liu , Yi Shi , Xi Cheng , Hualiang Jiang , H Eric Xu , Yan Zhang , Xin Xie , Yi Jiang

Journal: Nat Commun

PubMed ID: 35292680

Doi: 10.1038/s41467-022-29072-3

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A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination

Authors: Karen Colwill, Yannick Galipeau, Matthew Stuible, Christian Gervais, Corey Arnold, Bhavisha Rathod, Kento T Abe, Jenny H Wang, Adrian Pasculescu, Mariam Maltseva, Lynda Rocheleau, Martin Pelchat, Mahya Fazel-Zarandi, Mariam Iskilova, Miriam Barrios-Rodiles, Linda Bennett, Kevin Yau, François Cholette, Christine Mesa, Angel X Li, Aimee Paterson, Michelle A Hladunewich, Pamela J Goodwin, Jeffrey L Wrana, Steven J Drews, Samira Mubareka, Allison J McGeer, John Kim, Marc-André Langlois, Anne-Claude Gingras, Yves Durocher

Journal: Clin Transl Immunology

PubMed ID: 35356067

Doi: 10.1002/cti2.1380

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Molecular characterization, immunofluorescent localization, and expression levels of two bicarbonate anion transporters in the whitish mantle of the giant clam, Tridacna squamosa, and the implications for light-enhanced shell formation

Authors: Mel V Boo, Caryn Z Pang, Shit F Chew, Yuen K Ip

Journal: Comp Biochem Physiol A Mol Integr Physiol

PubMed ID: 35337976

Doi: 10.1016/j.cbpa.2022.111200

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Dynamic observation of SARS-CoV-2 IgM, IgG, and neutralizing antibodies in the development of population immunity through COVID-19 vaccination

Authors: Ruiwei Jiang, Xiaowen Dou, Min Li, Enyun Wang, Jiwen Hu, Dan Xiong, Xiuming Zhang

Journal: J Clin Lab Anal

PubMed ID: 35235705

Doi: 10.1002/jcla.24325

Fine Mapping of the Region Identified rs7175517 as a Causal Variant Related to BMI in China and the United Kingdom Populations

Authors: Ce Lu, Hai-Jun Wang, Jie-Yun Song, Shuo Wang, Xue-Ying Li, Tao Huang, Hui Wang

Journal: Front Genet

PubMed ID: 35368675

Doi: 10.3389/fgene.2022.838685

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