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Clade-Specific Alterations within the HIV-1 Capsid Protein with Implications for Nuclear Translocation

Authors: Alexej Dick, Megan E Meuser, Simon Cocklin

Journal: Biomolecules

PubMed ID: 35625621

Doi: 10.3390/biom12050695

Products & Services: Recombinant Antibody Expression

Novel role of the synaptic scaffold protein Dlgap4 in ventricular surface integrity and neuronal migration during cortical development

Authors: Delfina M Romero, Karine Poirier, Richard Belvindrah, Imane Moutkine, Anne Houllier, Anne-Gaëlle LeMoing, Florence Petit, Anne Boland, Stephan C Collins, Mariano Soiza-Reilly, Binnaz Yalcin, Jamel Chelly, Jean-François Deleuze, Nadia Bahi-Buisson, Fiona Francis

Journal: Nat Commun

PubMed ID: 35585091

Doi: 10.1038/s41467-022-30443-z

Products & Services: Mammalian Expression

Efficient suppression of endogenous CFTR nonsense mutations using anticodon-engineered transfer RNAs

Authors: Wooree Ko, Joseph J Porter, Matthew T Sipple, Katherine M Edwards, John D Lueck

Journal: Mol Ther Nucleic Acids

PubMed ID: 35664697

Doi: 10.1016/j.omtn.2022.04.033

Products & Services: PCR Cloning and Subcloning

Fibroblast growth factor homologous factors serve as a molecular rheostat in tuning arrhythmogenic cardiac late sodium current

Authors: Nourdine Chakouri, Sharen Rivas, Daniel Roybal, Lin Yang, Johanna Diaz, Allen Hsu, Ryan Mahling, Bi-Xing Chen, Josiah O Owoyemi, Deborah DiSilvestre, Dario Sirabella, Barbara Corneo, Gordon F Tomaselli, Ivy E Dick, Steven O Marx, Manu Ben-Johny

Journal: Nat Cardiovasc Res

PubMed ID: 35662881

Doi: 10.1038/s44161-022-00060-6

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Gibbin mesodermal regulation patterns epithelial development

Authors: Ann Collier, Angela Liu, Jessica Torkelson, Jillian Pattison, Sadhana Gaddam, Hanson Zhen, Tiffany Patel, Kelly McCarthy, Hana Ghanim, Anthony E Oro

Journal: Nature

PubMed ID: 35585237

Doi: 10.1038/s41586-022-04727-9

Products & Services: Custom DNA/RNA Oligos

Scalable Process for High-Yield Production of CyRPA Using Insect Cells for Inclusion in a Malaria Virosome-Based Vaccine Candidate

Authors: Bárbara Fernandes, Marcos Sousa, Rute Castro, Anja Schäfer, Julia Hauser, Kai Schulze, Mario Amacker, Marco Tamborrini, Gerd Pluschke, Paula M Alves, Sylvain Fleury, António Roldão

Journal: Front Bioeng Biotechnol

PubMed ID: 35669054

Doi: 10.3389/fbioe.2022.879078

Products & Services: Plasmid DNA Preparation

Furin and TMPRSS2 Resistant Spike Induces Robust Humoral and Cellular Immunity Against SARS-CoV-2 Lethal Infection

Authors: Jhe-Jhih Lin, Chih-Feng Tien, Yi-Ping Kuo, En-Ju Lin, Wei-Hsiang Tsai, Ming-Yu Chen, Pei-Ju Tsai, Yu-Wen Su, Nikhil Pathak, Jinn-Moon Yang, Chia-Yi Yu, Zih-Shiuan Chuang, Han-Chieh Wu, Wan-Ting Tsai, Shih-Syong Dai, Hung-Chun Liao, Kit Man Chai, Yu-Siang Su, Tsung-Hsien Chuang, Shih-Jen Liu, Hsin-Wei Chen, Horng-Yunn Dou, Feng-Jui Chen, Chiung-Tong Chen, Chin-Len Liao, Guann-Yi Yu

Journal: Front Immunol

PubMed ID: 35585971

Doi: 10.3389/fimmu.2022.872047

Products & Services: Codon Optimization

PI Kinase-EhGEF2-EhRho5 axis contributes to LPA stimulated macropinocytosis in Entamoeba histolytica

Authors: Achala Apte, Maria Manich, Elisabeth Labruyère, Sunando Datta

Journal: PLoS Pathog

PubMed ID: 35594320

Doi: 10.1371/journal.ppat.1010550

Products & Services: Bacterial Expression

The E3 ubiquitin ligase RNF216/TRIAD3 is a key coordinator of the hypothalamic-pituitary-gonadal axis

Authors: Arlene J George, Bin Dong, Hannah Lail, Morgan Gomez, Yarely C Hoffiz, Christopher B Ware, Ning Fang, Anne Z Murphy, Erik Hrabovszky, Desiree Wanders, Angela M Mabb

Journal: iScience

PubMed ID: 35620441

Doi: 10.1016/j.isci.2022.104386

Products & Services: Gene Synthesis

Structural Insights on the Conversion of Cytochrome P450 to P420

Authors: Jessica A Gable, Sarvind Tripathi, Thomas L Poulos

Journal: ACS Omega

PubMed ID: 35694512

Doi: 10.1021/acsomega.2c00960

Products & Services: Mutant Libraries

Naringenin upregulates GTPCH1/eNOS to ameliorate high glucose-induced retinal endothelial cell injury

Authors: Bing Xue, Yu Wang

Journal: Exp Ther Med

PubMed ID: 35607381

Doi: 10.3892/etm.2022.11355

Products & Services: Gene Synthesis

Gain-of-function pF28S variant in disrupts neuronal differentiation, migration and axonogenesis during cortical development, leading to neurodevelopmental disorder

Authors: Masashi Nishikawa, Marcello Scala, Muhammad Umair, Hidenori Ito, Ahmed Waqas, Pasquale Striano, Federico Zara, Gregory Costain, Valeria Capra, Koh-Ichi Nagata

Journal: J Med Genet

PubMed ID: 35595279

Doi: 10.1136/jmedgenet-2022-108483

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Curcumol alleviates liver fibrosis by inducing endoplasmic reticulum stress-mediated necroptosis of hepatic stellate cells through Sirt1/NICD pathway

Authors: Sumin Sun, Sheng Huan, Zhanghao Li, Yue Yao, Ying Su, Siwei Xia, Shijun Wang, Xuefen Xu, Jiangjuan Shao, Zili Zhang, Feng Zhang, Jinbo Fu, Shizhong Zheng

Journal: PeerJ

PubMed ID: 35582617

Doi: 10.7717/peerj.13376

Products & Services: Gene Synthesis

Immunogenicity and reactogenicity after booster dose with AZD1222 via intradermal route among adult who had received CoronaVac

Authors: Rapisa Nantanee, Puneyavee Aikphaibul, Peera Jaru-Ampornpan, Pimpayao Sodsai, Orawan Himananto, Tuangtip Theerawit, Jiratchaya Sophonphan, Punyot Tovichayathamrong, Kasama Manothummetha, Tysdi Laohasereekul, Narin Hiransuthikul, Nattiya Hirankarn, Thanyawee Puthanakit

Journal: Vaccine

PubMed ID: 35513961

Doi: 10.1016/j.vaccine.2022.04.067

Products & Services: Mammalian Expression

6-Valent Virus-Like Particle-Based Vaccine Induced Potent and Sustained Immunity Against Noroviruses in Mice

Authors: Wenli Hou, Lihui Lv, Yihan Wang, Man Xing, Yingying Guo, Di Xie, Xin Wei, Xiuyue Zhang, Hui Liu, Jiling Ren, Dongming Zhou

Journal: Front Immunol

PubMed ID: 35711416

Doi: 10.3389/fimmu.2022.906275

Products & Services: Monoclonal Antibody Services

Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia

Authors: Zhi Ruan, Kayo Takamatsu-Yukawa, Yuzhi Wang, Margaret L Ushman, Adam Thomas Labadorf, Maria Ericsson, Seiko Ikezu, Tsuneya Ikezu

Journal: Cell Rep

PubMed ID: 35545052

Doi: 10.1016/j.celrep.2022.110791

Products & Services: Mammalian Expression

Immune recall improves antibody durability and breadth to SARS-CoV-2 variants

Authors: Yuezhou Chen, Pei Tong, Noah Whiteman, Ali Sanjari Moghaddam, Mehrdad Zarghami, Adam Zuiani, Shaghayegh Habibi, Avneesh Gautam, F Keerti, Caihong Bi, Tianshu Xiao, Yongfei Cai, Bing Chen, Donna Neuberg, Duane R Wesemann

Journal: Sci Immunol

PubMed ID: 35549298

Doi: 10.1126/sciimmunol.abp8328

Products & Services: Proteins, Expression, Isolation and Analysis

Longitudinal variation in SARS-CoV-2 antibody levels and emergence of viral variants: a serological analysis

Authors: Frauke Muecksch, Helen Wise, Kate Templeton, Becky Batchelor, Maria Squires, Kirsty McCance, Lisa Jarvis, Kristen Malloy, Elizabeth Furrie, Claire Richardson, Jacqueline MacGuire, Ian Godber, Alana Burns, Sally Mavin, Fengwen Zhang, Fabian Schmidt, Paul D Bieniasz, Sara Jenks, Theodora Hatziioannou

Journal: Lancet Microbe

PubMed ID: 35636436

Doi: 10.1016/S2666-5247(22)00090-8

The dopamine transporter antiports potassium to increase the uptake of dopamine

Authors: Solveig G Schmidt, Mette Galsgaard Malle, Anne Kathrine Nielsen, Søren S-R Bohr, Ciara F Pugh, Jeppe C Nielsen, Ida H Poulsen, Kasper D Rand, Nikos S Hatzakis, Claus J Loland

Journal: Nat Commun

PubMed ID: 35508541

Doi: 10.1038/s41467-022-30154-5

Products & Services: Catalog Antibody

Exploring Calbindin-IMPase fusion proteins structure and activity

Authors: James W Noble, John R Atack

Journal: Biochem Biophys Rep

PubMed ID: 35540435

Doi: 10.1016/j.bbrep.2022.101266

Products & Services: Proteins, Expression, Isolation and Analysis

Knockout Alleviates DSS-Induced Colitis Regulating the Immune Function of Dendritic Cells

Authors: Wei Wei, Sucheng Mu, Yi Han, Yao Chen, Zhongshu Kuang, Xingyue Wu, Yue Luo, Chaoyang Tong, Yiqun Zhang, Yilin Yang, Zhenju Song

Journal: Front Immunol

PubMed ID: 35669778

Doi: 10.3389/fimmu.2022.841254

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Extracellular fructooligosaccharide degradation in Anaerostipes hadrus for co-metabolism with non-fructooligosaccharide utilizers

Authors: Akihito Endo, Hiroki Tanno, Ren Kadowaki, Tadashi Fujii, Takumi Tochio

Journal: Biochem Biophys Res Commun

PubMed ID: 35537289

Doi: 10.1016/j.bbrc.2022.04.134

Products & Services: Plasmid DNA Preparation

Electron transfer activity of the nanodisc-bound mitochondrial outer membrane protein mitoNEET

Authors: Homyra Tasnim, Huangen Ding

Journal: Free Radic Biol Med

PubMed ID: 35609862

Doi: 10.1016/j.freeradbiomed.2022.05.011

Products & Services: Custom Vector Construction

Role of Glutaminase 2 in Promoting CD4+ T Cell Production of Interleukin-2 by Supporting Antioxidant Defense in Systemic Lupus Erythematosus

Authors: Ryo Hisada, Nobuya Yoshida, Seo Yeon K Orite, Masataka Umeda, Catalina Burbano, Marc Scherlinger, Michihito Kono, Suzanne Krishfield, George C Tsokos

Journal: Arthritis Rheumatol

PubMed ID: 35254008

Doi: 10.1002/art.42112

Products & Services: Mammalian Expression

Development of an LNP-Encapsulated mRNA-RBD Vaccine against SARS-CoV-2 and Its Variants

Authors: Cong Liu, Nino Rcheulishvili, Zhigao Shen, Dimitri Papukashvili, Fengfei Xie, Ziqian Wang, Xingyun Wang, Yunjiao He, Peng George Wang

Journal: Pharmaceutics

PubMed ID: 35631687

Doi: 10.3390/pharmaceutics14051101

Products & Services: Proteins, Expression, Isolation and Analysis

The Inclusion Membrane Protein CTL0390 Mediates Host Cell Exit via Lysis through STING Activation

Authors: R Clayton Bishop, Isabelle Derré

Journal: Infect Immun

PubMed ID: 35587198

Doi: 10.1128/iai.00190-22

Products & Services: DNA Sequencing

The B-box1 domain of PML mediates SUMO E2-E3 complex formation through an atypical interaction with UBC9

Authors: Thomas Bregnard, Affrin Ahmed, Irina V Semenova, Sandra K Weller, Irina Bezsonova

Journal: Biophys Chem

PubMed ID: 35667129

Doi: 10.1016/j.bpc.2022.106827

Products & Services: Proteins, Expression, Isolation and Analysis

Specific N-glycans regulate an extracellular adhesion complex during somatosensory dendrite patterning

Authors: Maisha Rahman, Nelson J Ramirez-Suarez, Carlos A Diaz-Balzac, Hannes E Bülow

Journal: EMBO Rep

PubMed ID: 35586945

Doi: 10.15252/embr.202154163

Products & Services: Proteins, Expression, Isolation and Analysis

Influence of Cortisol on the Fibril Formation Kinetics of Aβ42 Peptide: A Multi-Technical Approach

Authors: Alessandro Nucara, Francesca Ripanti, Simona Sennato, Giacomo Nisini, Emiliano De Santis, Mahta Sefat, Marina Carbonaro, Dalila Mango, Velia Minicozzi, Marilena Carbone

Journal: Int J Mol Sci

PubMed ID: 35682687

Doi: 10.3390/ijms23116007

Products & Services: Proteins, Expression, Isolation and Analysis

Optical Fluorescence Imaging of Native Proteins Using a Fluorescent Probe with a Cell-Membrane-Permeable Carboxyl Group

Authors: Jung Min Kim, Young-Mi Kang

Journal: Int J Mol Sci

PubMed ID: 35628651

Doi: 10.3390/ijms23105841

Products & Services: Gene Synthesis

Electrochemical biosensor for rapid detection of fungal contamination in fuel systems

Authors: Osman Radwan, Michael C Brothers, Victoria Coyle, Molly E Chapleau, Richard R Chapleau, Steve S Kim, Oscar N Ruiz

Journal: Biosens Bioelectron

PubMed ID: 35605548

Doi: 10.1016/j.bios.2022.114374

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Rationally engineering santalene synthase to readjust the component ratio of sandalwood oil

Authors: Wenlong Zha, Fan Zhang, Jiaqi Shao, Xingmei Ma, Jianxun Zhu, Pinghua Sun, Ruibo Wu, Jiachen Zi

Journal: Nat Commun

PubMed ID: 35523896

Doi: 10.1038/s41467-022-30294-8

Products & Services: Proteins, Expression, Isolation and Analysis

Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex

Authors: Heidi Gytz Olesen, Iliana Michailidou, Wioleta M Zelek, Jeroen Vreijling, Patrick Ruizendaal, Ferry de Klein, J Arnoud Marquart, Thomas B Kuipers, Hailiang Mei, Yuchun Zhang, Muhammad Ahasan, Krista K Johnson, Yi Wang, B Paul Morgan, Marcus van Dijk, Kees Fluiter, Gregers Rom Andersen, Frank Baas

Journal: J Innate Immun

PubMed ID: 35551129

Doi: 10.1159/000524587

Products & Services: Plasmid DNA Preparation

An Ex Vivo 3D Tumor Microenvironment-Mimicry Culture to Study TAM Modulation of Cancer Immunotherapy

Authors: Yan-Ruide Li, Yanqi Yu, Adam Kramer, Ryan Hon, Matthew Wilson, James Brown, Lili Yang

Journal: Cells

PubMed ID: 35563889

Doi: 10.3390/cells11091583

Products & Services: GenParts™ DNA Fragments

[Not Available]

Authors: Kevin Yau, Christopher T Chan, Kento T Abe, Yidi Jiang, Mohammad Atiquzzaman, Sarah I Mullin, Ellen Shadowitz, Lisa Liu, Ema Kostadinovic, Tatjana Sukovic, Anny Gonzalez, Margaret E McGrath-Chong, Matthew J Oliver, Jeffrey Perl, Jerome A Leis, Shelly Bolotin, Vanessa Tran, Adeera Levin, Peter G Blake, Karen Colwill, Anne-Claude Gingras, Michelle A Hladunewich

Journal: CMAJ

PubMed ID: 35636760

Doi: 10.1503/cmaj.211881-f

Products & Services: Monoclonal Antibody Services

Brassica napus genes Rlm4 and Rlm7, conferring resistance to Leptosphaeria maculans, are alleles of the Rlm9 wall-associated kinase-like resistance locus

Authors: Parham Haddadi, Nicholas J Larkan, Angela Van deWouw, Yueqi Zhang, Ting Xiang Neik, Elena Beynon, Philipp Bayer, Dave Edwards, Jacqueline Batley, Mohammad Hossein Borhan

Journal: Plant Biotechnol J

PubMed ID: 35338565

Doi: 10.1111/pbi.13818

Products & Services: Gene Synthesis

LncRNA OIP5-AS1 modulates the proliferation and apoptosis of Jurkat cells by sponging miR-181c-5p to regulate IL-7 expression in myasthenia gravis

Authors: Xu Wang, Huixue Zhang, Xiaoyu Lu, Shuang Li, Xiaotong Kong, Li Liu, Lifang Li, Si Xu, Tianfeng Wang, Jianjian Wang, Lihua Wang

Journal: PeerJ

PubMed ID: 35602889

Doi: 10.7717/peerj.13454

Products & Services: Gene Synthesis

Binding Properties of RNA Quadruplex of SARS-CoV-2 to Berberine Compared to Telomeric DNA Quadruplex

Authors: Rosario Oliva, Sanjib Mukherjee, Magiliny Manisegaran, Marco Campanile, Pompea Del Vecchio, Luigi Petraccone, Roland Winter

Journal: Int J Mol Sci

PubMed ID: 35628500

Doi: 10.3390/ijms23105690

Products & Services: Gene Synthesis

Homologous or heterogenous vaccination boosters enhance neutralizing activities against SARS-CoV-2 Omicron BA1 variant

Authors: Zhongcheng Zhou, Peng Du, Ning Li, Xinxin Xiong, Shengjun Tang, Qinjin Dai, Taorui Wang, Meixing Yu, Miao Man, Kelvin Lam, Daniel T Baptista-Hon, Wa Hou Tai, Olivia Monteiro, Weng Sam Ng, Un Man Lee, Zhihai Liu, Kang Zhang, Gen Li

Journal: MedComm (2020)

PubMed ID: 35592756

Doi: 10.1002/mco2.143

Products & Services: Plasmid DNA Preparation

Identification of Epitopes on Rhinovirus 89 Capsid Proteins Capable of Inducing Neutralizing Antibodies

Authors: Katarzyna Niespodziana, Clarissa R Cabauatan, Petra Pazderova, Phyllis C Vacal, Judith Wortmann, Walter Keller, Peter Errhalt, Rudolf Valenta

Journal: Int J Mol Sci

PubMed ID: 35563505

Doi: 10.3390/ijms23095113

Products & Services: GenParts™ DNA Fragments

A Facile Method to Produce N-Terminally Truncated α-Synuclein

Authors: Rebecca J Thrush, Devkee M Vadukul, Francesco A Aprile

Journal: Front Neurosci

PubMed ID: 35692420

Doi: 10.3389/fnins.2022.881480

Products & Services: Plasmid DNA Preparation

Cryo-EM structures of the human surfactant lipid transporter ABCA3

Authors: Tian Xie, Zike Zhang, Jian Yue, Qi Fang, Xin Gong

Journal: Sci Adv

PubMed ID: 35394827

Doi: doi/10.1126/sciadv.abn3727

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LC3 subfamily in cardiolipin-mediated mitophagy: a comparison of the LC3A, LC3B and LC3C homologs

Authors: Marina N Iriondo , Asier Etxaniz , Yaiza R Varela , Uxue Ballesteros , Javier H Hervás , L Ruth Montes , Félix M Goñi , Alicia Alonso

Journal: Autophagy

PubMed ID: 35414338

Doi: 10.1080/15548627.2022.2062111

Products & Services: PCR Cloning and Subcloning

Amyloid fishing: β-Amyloid adsorption using tailor-made coated titania nanoparticles

Authors: Elad Arad , Raz Jelinek , Hanna Rapaport

Journal: Colloids Surf B Biointerfaces

PubMed ID: 35121429

Doi: 10.1016/j.colsurfb.2022.112374

Products & Services: Peptide Synthesis

Targeting intrinsically disordered regions facilitates discovery of CaV3.2 inhibitory peptides for AAV-mediated peripheral analgesia

Authors: Seung Min Shin , Justas Lauzadis , Brandon Itson-Zoske , Yongsong Cai 1 , Fan Fan , Gayathri Natarajan , Wai-Meng Kwok , Michelino Puopolo , Quinn H Hogan , Hongwei Yu

Journal: Pain

PubMed ID: 35420557

Doi: 10.1097/j.pain.0000000000002650

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Specific knockdown of by CRISPR-CasRx prevents acquired sensorineural hearing loss in mice

Authors: Yang Guo, Lei Han, Shuang Han, Honghai Tang, Shengyi Wang, Chong Cui, Bing Chen, Huawei Li, Yilai Shu

Journal: Mol Ther Nucleic Acids

PubMed ID: 35615000

Doi: 10.1016/j.omtn.2022.04.014

Products & Services: Proteins, Expression, Isolation and Analysis

Immmunoinformatics-based design of a multi-epitope vaccine with CTLA-4 extracellular domain to combat Helicobacter pylori

Authors: Zhenyu Ru, Mingkai Yu, Yuejie Zhu, Zhiqiang Chen, Fengbo Zhang, Zhiqiang Zhang, Jianbing Ding

Journal: FASEB J

PubMed ID: 35294065

Doi: 10.1096/fj.202101538RR

Products & Services: Molecular Biology Tools

p53 alters intracellular Ca signaling through regulation of TRPM4

Authors: Sven Kappel, Daniela Ross-Kaschitza, Barbara Hauert, Karen Rother, Christine Peinelt

Journal: Cell Calcium

PubMed ID: 35500522

Doi: 10.1016/j.ceca.2022.102591

Products & Services: Proteins, Expression, Isolation and Analysis

a New IFN-Inducible Human Member of the Ly6a Subfamily Expressed by Spleen Cells and Associated with Inflammation and Viral Resistance

Authors: Moriya Shmerling, Michael Chalik, Nechama I Smorodinsky, Alan Meeker, Sujayita Roy, Orit Sagi-Assif, Tsipi Meshel, Artem Danilevsky, Noam Shomron, Shmuel Levinger, Bar Nishry, David Baruchi, Avital Shargorodsky, Ravit Ziv, Avital Sarusi-Portuguez, Maoz Lahav, Marcelo Ehrlich, Bryony Braschi, Elspeth Bruford, Isaac P Witz, Daniel H Wreschner

Journal: Immunohorizons

PubMed ID: 35440514

Doi: 10.4049/immunohorizons.2200018

Products & Services: DNA Sequencing

A Bacterially Expressed SARS-CoV-2 Receptor Binding Domain Fused With Cross-Reacting Material 197 A-Domain Elicits High Level of Neutralizing Antibodies in Mice

Authors: Liqin Liu, Tingting Chen, Lizhi Zhou, Jie Sun, Yuqian Li, Meifeng Nie, Hualong Xiong, Yuhe Zhu, Wenhui Xue, Yangtao Wu, Tingting Li, Tianying Zhang, Zhibo Kong, Hai Yu, Jun Zhang, Ying Gu, Qingbing Zheng, Qinjian Zhao, Ningshao Xia, Shaowei Li

Journal: Front Microbiol

PubMed ID: 35558112

Doi: 10.3389/fmicb.2022.854630

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