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A biomimetic nanodisc system selectively activates type I interferons by nonclassical STING pathway for cancer immunotherapy

Authors: Qianwen Mu, Haolan Deng, Shuo Li, Xiaoyu An, Xuan Liu, Yue Xi, Hao Liang, Di Sun, Xiaojun Wang, Xue Liu, Gang Liu, Chao Liu

Journal: Nature Communications

PubMed ID: 41917023

Doi: 10.1038/s41467-026-71363-6

Products & Services: Peptide Synthesis Protein Electrophoresis and Western

High-Entropy Alloy Synergized with Gene Editing for Cocktail-Sensitized Radioimmunotherapy of Lung Metastases

Authors: Qianglan Lu, Chengwei Ye, Ruiyue Chen, Zhanqi Xing, Zhiyong Liu, Fei Zeng, Jinglang Gong, Yanfeng Gao, Xiaolian Sun, Shaochun Tang, Yujun Song

Journal: ADVANCED MATERIALS

PubMed ID: 41914367

Doi: 10.1002/adma.202522618

Products & Services: Synthetic Guide RNA

A Oligomer Dissociation Is Catalyzed by Fibril Surfaces

Authors: Alexander J. Dear; Dev Thacker; Stefan Wennmalm; Lei Ortigosa-Pascual; Ewa A. Andrzejewska; Georg Meisl; Sara Linse; Tuomas P. J. Knowles

Journal: ACS Chemical Neuroscience

PubMed ID: 38785363

Doi: 10.1021/acschemneuro.4c00127

A Oligomer Dissociation Is Catalyzed by Fibril Surfaces

Authors: Alexander J. Dear; Dev Thacker; Stefan Wennmalm; Lei Ortigosa-Pascual; Ewa A. Andrzejewska; Georg Meisl; Sara Linse; Tuomas P. J. Knowles

Journal: ACS Chemical Neuroscience

PubMed ID: 38785363

Doi: 10.1021/acschemneuro.4c00127

Structural insights into lipid membrane binding by human ferlins

Authors: Constantin Cretu; Aleksandar Chernev; Csaba Zolt n Kib di Szab ; Vladimir Pena; Henning Urlaub; Tobias Moser; Julia Preobraschenski

Journal: The EMBO Journal

PubMed ID: 40437073

Doi: 10.1038/s44318-025-00463-8

Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis

Authors: Andrew I Wong; Tiago Beites; Kyle A Planck; Rachael A Fieweger; Kathryn A Eckartt; Shuqi Li; Nicholas C Poulton; Brian C VanderVen; Kyu Y Rhee; Dirk Schnappinger; Sabine Ehrt; Jeremy Rock; Bavesh D Kana

Journal: Elife

PubMed ID: 36810158

Doi: 10.7554/eLife.81177

Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis

Journal: Elife

PubMed ID: 36810158

Doi: 10.7554/eLife.81177

Mechanistic insights into the small-molecule inhibition of influenza A virus entry

Authors: Yan Xu; Varada Anirudhan; Irina N. Gaisina; Haijuan Du; Saad Alqarni; Terry W. Moore; Michael Caffrey; Balaji Manicassamy; Tongqing Zhou; Lijun Rong; Kai Xu

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 40802690

Doi: 10.1073/pnas.2503899122

Screening of a novel VHH pair targeting different epitopes of D-dimer and development of a sandwich luminex immunoassay for plasma D-dimer detection

Authors: Congcong Jia, Min Zhu, Yingtung Lo, Meixiang Yu, Xinyi Xia, Weiwei Ji, Xiang Cao, Yakun Wan, Jianzhong Lu, Hai Zhang

Journal: Analytica Chimica Acta

PubMed ID: 41903976

Doi: 10.1016/j.aca.2026.345368

Products & Services: Custom Vector Construction

mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy

Authors: Jiayan Fu, Yaoqi Liu, Zhenyu Zhong, Benyuan Cao, Luna Ran, Zijia Guo, Haiyang Dong, Nengcheng Bao, Rongqing Pan, Jinqiang Wang, Yuanhui Mao, Yongfeng Jin

Journal: Cell Reports Medicine

PubMed ID: 41916290

Doi: 10.1016/j.xcrm.2026.102706

Products & Services: Peptide Synthesis