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GPR183 potentiates CAR-T cell infiltration and antitumor immunity through a positive feedback loop involving the oxysterol 7α,25-OHC

Authors: Rui Guo, Chang Guo, Sen Qin, Zhiwen Lin, Jinlian Tong, Yiran Wang, Zixuan Zhao, Wen Zuo, Qing Gao, Qin Tan, Jie Ma

Journal: Molecular cancer

PubMed ID: 41840629

Doi: 10.1186/s12943-026-02642-5

Products & Services: Synthetic Guide RNA Custom DNA/RNA Oligos

CellCousin2: an optimized system for partial ablation and tracing of regenerative lineages

Authors: Gabriel Garnik Hovhannisyan, Tawba Akhourbi, Sema Elif Eski, Isabelle Pirson, Esteban N Gurzov, Sumeet Pal Singh

Journal: NPJ Regenerative medicine

PubMed ID: 41912583

Doi: 10.1038/s41536-026-00473-y

Products & Services: Gene Fragments

Dihydrotanshinone as a Natural Product-Based CYP17A1 Lyase Inhibitor for Hyperandrogenic Disorders

Authors: Kaige Li; Jibira Yakubu; Flemming Steen J rgensen; Amit V. Pandey

Journal: Biomolecules

PubMed ID: 41594684

Doi: 10.3390/biom16010144

Cell type dependent stability and virulence of a recombinant SARS-CoV-2, and engineering of a propagation deficient RNA replicon to analyze virus RNA synthesis

Authors: Li Wang; Mar a Guzman; Diego Mu oz-Santos; Jose Manuel Honrubia; Jorge Ripoll-Gomez; Rafael Delgado; Isabel Sola; Luis Enjuanes; Sonia Zu iga

Journal: Frontiers in cellular and infection microbiology

PubMed ID: 37942479

Doi: 10.3389/fcimb.2023.1268227

Epistasis in the receptor-binding domain of contemporary H3N2 viruses that reverted to bind sialylated di-LacNAc repeats

Authors: Ruonan Liang; Francesca Peccati; Niels L.D. Ponse; Elif Uslu; Annelies J.H. de Rooij; Alvin X. Han; Geert-Jan Boons; Luca Unione; Robert P. de Vries

Journal: Cell Reports

PubMed ID: 40679911

Doi: 10.1016/j.celrep.2025.116007

Mechanistic insights into the small-molecule inhibition of influenza A virus entry

Authors: Yan Xu; Varada Anirudhan; Irina N. Gaisina; Haijuan Du; Saad Alqarni; Terry W. Moore; Michael Caffrey; Balaji Manicassamy; Tongqing Zhou; Lijun Rong; Kai Xu

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 40802690

Doi: 10.1073/pnas.2503899122

89Zr/177Lu-Labeled Radioimmunoconjugates Targeting SORT1 for Cancer Theranostics

Authors: Jingyue Gao, Tianyi Cen, Junyi Chen, Xinwei Li, Xiaowei Fan, Mengxin Xu, Feng Gao, Zhibo Liu

Journal: Journal of Medicinal Chemistry

PubMed ID: 41773941

Doi: 10.1021/acs.jmedchem.6c00007

Products & Services: Custom Vector Construction

CRISPR/Cas9-Based Vanadium MXene-Free Radical Spatiotemporally Controlled Nanoreactor for Photothermal-Induced Multi-Effect Synergistic Antitumor Therapy

Authors: Zi-Jian Huang, Feng-Ming Li, Yi-Fan Tu, Ke-Ke Feng, Cheng-Lei Li, Shi-Cheng Tian, Yong-Shan Hu, Jing-Wei Shao, Zhen-Hua Liu

Journal: Advanced Science

PubMed ID: 41818620

Doi: 10.1002/advs.202522535

Products & Services: Peptide Synthesis

Cyclic guanosine monophosphate-protein kinase G signaling attenuates aortic valve calcification through ULK1-mediated autophagy

Authors: Yan Wang, Fei Xu, Chengxiang Song, Xi Wang, Hao Zhou, Tianyi Qu, Hongde Li, Qiang Luo, Wenhua Lei, Yue Yin, Fangyang Huang, Mao Chen

Journal: Signal transduction and targeted therapy

PubMed ID: 41820291

Doi: 10.1038/s41392-026-02624-5

Products & Services: Custom mRNA synthesis

The mechanism of ribosomal recruitment during translation initiation on the Type 2 encephalomyocarditis virus IRES

Authors: Sayan Bhattacharjee, Irina S Abaeva, Zuben P Brown, Yani Arhab, Hengameh Fallah, Christopher U T Hellen, Joachim Frank, Tatyana V Pestova

Journal: The EMBO Journal

PubMed ID: 41851500

Doi: 10.1038/s44318-026-00735-x

Products & Services: Protein Electrophoresis and Western Mutagenesis Services