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Systematic profiling reveals betaine as an exercise mimetic for geroprotection

Authors: Lingling Geng, Jiale Ping, Ruochen Wu, Haoteng Yan, Hui Zhang, Yuan Zhuang, Taixin Ning, Jun Wang, Chuqian Liang, Jiachen Zhang, Qingqing Chu, Jing Zhang, Yifan Wen, Yaobin Jing, Shuhui Sun, Qin Qiao, Qian Zhao, Qianzhao Ji, Shuai Ma, Yusheng Cai, Yandong Zheng, Zhiran Zou, Zhiqing Diao, Mingheng Li, Hao Zhang, Jianli Hu, Liangzheng Fu, Wang Kang, Ruijun Bai, Hongkai Zhao, Sheng Zhang, Yingjie Ding, Jinghui Lei, Wei Wang, Yun Ji, Bo Gou, Guoqiang Sun, Jian Yin, Pengze Yan, Hao Li, Zehua Wang, Shikun Ma, Zunpeng Liu, Hezhen Shan, Qiaoran Wang, Tianling Cao, Shanshan Yang, Cui Wang, Ping Yang, Yanling Fan, Yanxia Ye, Jinghao Hu, Mengmeng Jiang, Ye Wang, Kan Liu, Yujing Li, Yuanxiang Li, Jingyi Li, Weimin Ci, Zi-Bing Jin, Xiaobing Fu, Xu Zhang, Guoguang Zhao, Juan Carlos Izpisua Belmonte, Si Wang, Moshi Song, Weiqi Zhang, Jing Qu, Guang-Hui Liu

Journal: Cell

PubMed ID: 40570836

Doi: 10.1016/j.cell.2025.06.001

Products & Services: Synthetic Guide RNA

RING-Between-RING-Type E3 Ligase Ariadne-Like Protein 8 Negatively Regulates Plant Virus Infection by Targeting a Viral Movement Protein

Authors: Wenli Li, Chenchen Zhong, Jiangning Duan, Changyi Zhan, Zhaolei Li, Xinyu Zhang, Dingliang Zhang, Deshui Liu, Zhiyan Wen, Xiaofei Zhao, Meng Yang, Dawei Li, Yongliang Zhang

Journal: Advanced Science

PubMed ID: 40908568

Doi: 10.1002/advs.202509942

Functional characterisation of missense ceruloplasmin variants and real-world prevalence assessment of Aceruloplasminemia using population data

Authors: Nicole Ziliotto; Sara Lencioni; Martina Cirinciani; Alan Zanardi; Massimo Alessio; Giulia Sold ; Eleonora Da Pozzo; Rosanna Asselta; Andrea Caricasole

Journal: EBioMedicine

PubMed ID: 40043514

Doi: 10.1016/j.ebiom.2025.105625

Functional characterisation of missense ceruloplasmin variants and real-world prevalence assessment of Aceruloplasminemia using population data

Authors: Nicole Ziliotto; Sara Lencioni; Martina Cirinciani; Alan Zanardi; Massimo Alessio; Giulia Sold ; Eleonora Da Pozzo; Rosanna Asselta; Andrea Caricasole

Journal: EBioMedicine

PubMed ID: 40043514

Doi: 10.1016/j.ebiom.2025.105625

A tick saliva serpin, Ixs S17 inhibits host innate immune system proteases and enhances host colonization by Lyme disease agent

Authors: Thu-Thuy Nguyen; Tae Heung Kim; Emily Bencosme-Cuevas; Jacquie Berry; Alex Samuel Kiarie Gaithuma; Moiz Ashraf Ansari; Tae Kwon Kim; Lucas Tirloni; Zeljko Radulovic; James J. Moresco; John R. Yates; Albert Mulenga

Journal: PLOS Pathogens

PubMed ID: 38394332

Doi: 10.1371/journal.ppat.1012032

Products & Services: Monoclonal Antibody Services

A tick saliva serpin, Ixs S17 inhibits host innate immune system proteases and enhances host colonization by Lyme disease agent

Journal: PLOS Pathogens

PubMed ID: 38394332

Doi: 10.1371/journal.ppat.1012032

Products & Services: Monoclonal Antibody Services

Protein M fusion proteins and uses

Authors: Jay Dela Cruz , Moreno Valley , CA

Journal: U.S. Patent

Doi: US11401309B2

Products & Services: Gene Synthesis Plasmid DNA Preparation Catalog Antibodies Codon Optimization

Multilevel regulation of c-di-GMP biosynthesis by cAMPsignalingincreasesShigellasonneifitnessand pathogenicity in response to bile salts

Authors: Mingfang Wang, Jia Zeng, Binbin Cui, Guangliang Wu, Xiayu Chen, Yikai Fu, Bing Gu, Yinyue Deng

Journal: Cell Rep

PubMed ID: 40966079

Doi: 10.1016/j.celrep.2025.116306

Products & Services: Protein Electrophoresis and Western

Optimized in vivo base editing restores auditory function in a DFNA15 mouse model

Authors: Man Wang, Ziyu Zhang, Xiaohan Wang, Liyan Zhang, Xiangyan Chen, Nianci Li, Qiuhan Sun, Yicheng Lu, Zuhong He, Hongbo Yang, Fangzhi Tan, Jieyu Qi, Renjie Chai

Journal: Nature Communications

PubMed ID: 40968144

Doi: 10.1038/s41467-025-63613-w.

Products & Services: Protein and Antibody Isolation

Multifunctional NAC transcription factor SlJA2L integrates the ethylene pathway to orchestrate thermotolerance and fruit ripening in tomato

Authors: Yunfei Liang, Fang Ma, Shudi Huang, Chao Ma, Hongyan Shi, Fanyi Meng, Yinglu Chen, Han Dong, Rugang Chen, Xiangqiang Zhan

Journal: New Phytologist

PubMed ID: 40963426

Doi: 10.1111/nph.70571

Products & Services: Catalog Antibodies