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页码: 57/5357 每页显示数量

Elucidating the Substrate Envelope of Enterovirus 68-3C Protease: Structural Basis of Specificity and Potential Resistance

Authors: Vincent N. Azzolino; Ala M. Shaqra; Akbar Ali; Nese Kurt Yilmaz; Celia A. Schiffer

Journal: Viruses

PubMed ID: 39339895

Doi: 10.3390/v16091419

Products & Services: Peptide Synthesis

Development of Pyrimido Pyridazine Analogs through Increased Whole Cell Target Engagement of the Dihydropteroate Synthase Pterin Binding Site in Gram-Negative Bacteria

Authors: Hannah E. Snoke; Stephanie M. Reeve; Suresh Dharuman; Miranda J. Wallace; Victoria C. Loudon; Ying Zhao; John J. Bowling; Patricia A. Murphy; Brett Waddell; Robin B. Lee; J rgen B. Bulitta; Richard E. Lee

Journal: ACS Infectious Diseases

PubMed ID: 41116192

Doi: 10.1021/acsinfecdis.5c00635

Development of Pyrimido Pyridazine Analogs through Increased Whole Cell Target Engagement of the Dihydropteroate Synthase Pterin Binding Site in Gram-Negative Bacteria

Journal: ACS Infectious Diseases

PubMed ID: 41116192

Doi: 10.1021/acsinfecdis.5c00635

Development of Pyrimido Pyridazine Analogs through Increased Whole Cell Target Engagement of the Dihydropteroate Synthase Pterin Binding Site in Gram-Negative Bacteria

Journal: ACS Infectious Diseases

PubMed ID: 41116192

Doi: 10.1021/acsinfecdis.5c00635

The fibroblast-driven melanoma/Treg vitiligo mouse model is effectively suppressed by IFN blocking antibody

Authors: Yuhua Xie; Jun Cui; Yanhua Lu; Yingxue Du; Jianmin Chang

Journal: Frontiers in Medicine

PubMed ID: 41080931

Doi: 10.3389/fmed.2025.1677626

Products & Services: Monoclonal Antibody Services

Browning white adipose tissue using adipose stromal cell-targeted resveratrol-loaded nanoparticles for combating obesity

Authors: Yujiao Zu; Ling Zhao; Lei Hao; Yehia Mechref; Masoud Zabet-Moghaddam; Peter A. Keyel; Mehrnaz Abbasi; Dayong Wu; John A. Dawson; Ruiwen Zhang; Shufang Nie; Naima Moustaid-Moussa; Mikhail G. Kolonin; Alexes C. Daquinag; Luis Brandi; Irfan Warraich; Susan K. San Francisco; Xiaocun Sun; Zhaoyang Fan; Shu Wang

Journal: Journal of controlled release : official journal of the Controlled Release Society

PubMed ID: 33766692

Doi: 10.1016/j.jconrel.2021.03.022

Products & Services: Peptide Synthesis

Browning white adipose tissue using adipose stromal cell-targeted resveratrol-loaded nanoparticles for combating obesity

Journal: Journal of controlled release : official journal of the Controlled Release Society

PubMed ID: 33766692

Doi: 10.1016/j.jconrel.2021.03.022

Products & Services: Peptide Synthesis

AI-assisted design of ligands for lipocalin-2

Authors: Jacopo Sgrignani; Sara Buscarini; Patrizia Locatelli; Concetta Guerra; Alberto Furlan; Yingyi Chen; Giada Zoppi; Andrea Cavalli

Journal: Frontiers in Immunology

PubMed ID: 41019093

Doi: 10.3389/fimmu.2025.1631868

Integration of humanized ROBO1 CAR in PD-1 locus in natural killer cells delivers synergistic tumor-killing effect against nonsmall cell lung cancer

Authors: Jia-Hao Tao, Jun Zhang, Chun-Yan Tang, Jia-Xi Duan, Wen-Jing Zhong, Chen-Yu Zhang, Yu-Biao Liu, Jin Ling, Hua-Shun Li, Yong Zhou, Cha-Xiang Guan

Journal: Cancer gene therapy

PubMed ID: 40913086

Doi: 10.1038/s41417-025-00957-x

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Reinforced plant-derived lipid nanoparticles for oral precise epigenome editing in colonic diseases

Authors: Qiang Gao, Yunxia Gao, Yingui Cao, Haiting Xu, Ya Ma, Menghang Zu, Qiang Yang, Kun Yang, Zhenhua Zhu, Chao Liu, Xiaoxiao Shi, Rui L Reis, Subhas C Kundu, Shengyun Ma, Hesong Han, Bo Xiao

Journal: SCIENCE ADVANCES

PubMed ID: 41004579

Doi: 10.1126/sciadv.adw9275

Products & Services: Catalog Gene Editing