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页码: 143/5356 每页显示数量

PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins

Authors: Christopher R Horne, Toby A Dite, Samuel N Young, Lucy J Mather, Laura F Dagley, Jared L Johnson, Tomer M Yaron-Barir, Emily M Huntsman, Leonard A Daly, Dominic P Byrne, Antonia L Cadell, Boaz H Ng, Jumana Yousef, Dylan H Multari, Lianju Shen, Luke M McAloon, Gerard Manning, Mark A Febbraio, Anthony R Means, Lewis C Cantley, Maria C Tanzer, David R Croucher, Claire E Eyers, Patrick A Eyers, John W Scott, James M Murphy

Journal: Proc Natl Acad Sci U S A

PubMed ID: 39964718

Doi: 10.1073/pnas.2420961122

Products & Services: Peptide Synthesis

Enhancing mRNA translation efficiency by introducing sequence optimized AU-rich elements in 3′ UTR via HuR anchorage

Authors: Xinghuan Ma , Sujia Liu , Bangda Fan , Danni Jin , Lei Miao , Lin Liu , Shubo Du , Jiaqi Lin

Journal: Mol Ther Nucleic Acids

PubMed ID: 40125272

Doi: doi.org/10.1016/j.omtn.2025.102485

Products & Services: Gene Synthesis

Controllable intein splicing and N-terminal cleavage at mesophilic temperatures

Authors: Taylor A McNeal, Joel Weinberger, Geraldy L S Liman, Tia M Ariagno, David W Wood, Thomas J Santangelo, Christopher W Lennon

Journal: Front Bioeng Biotechnol

PubMed ID: 39991137

Doi: 10.3389/fbioe.2025.1543573

Products & Services: Gene Synthesis Mutagenesis Services

ABC transporter activity is affected by the size of lipid nanodiscs

Authors: Annabella Nouel Barreto, Luis G Cuello, Maria E Zoghbi

Journal: FEBS Letters

PubMed ID: 39748569

Doi: 10.1002/1873-3468.15096

Products & Services: Gene Synthesis Custom Vector Construction

Molecular mechanisms of drug resistance and compensation in SARS-CoV-2 main protease: the interplay between E166 and L50

Authors: Sarah N. Zvornicanin; Ala M. Shaqra; Julia Flynn; Heidi Carias Martinez; Weiping Jia; Stephanie Moquin; Dustin Dovala; Daniel N. Bolon; Nese Kurt Yilmaz; Celia A. Schiffer

Journal: MBio

PubMed ID: 40183562

Doi: 10.1128/mbio.04068-24

Products & Services: Peptide Synthesis

The serine protease DPP9 and the redox sensor KEAP1 form a mutually inhibitory complex

Authors: Lydia P. Tsamouri; Jeffrey C. Hsiao; Daniel A. Bachovchin

Journal: The Journal of Biological Chemistry

PubMed ID: 39615677

Doi: 10.1016/j.jbc.2024.108034

The serine protease DPP9 and the redox sensor KEAP1 form a mutually inhibitory complex

Authors: Lydia P. Tsamouri; Jeffrey C. Hsiao; Daniel A. Bachovchin

Journal: The Journal of Biological Chemistry

PubMed ID: 39615677

Doi: 10.1016/j.jbc.2024.108034

Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies

Authors: Yan-Ruide Li, Ying Fang, Siyue Niu, Yichen Zhu, Yuning Chen, Zibai Lyu, Enbo Zhu, Yanxin Tian, Jie Huang, Valerie Rezek, Scott Kitchen, Tzung Hsiai, Jin J Zhou, Pin Wang, Wanxing Chai-Ho, Sunmin Park, Christopher S Seet, Caspian Oliai, Lili Yang

Journal: Nature Communications

PubMed ID: 39893165

Doi: 10.1038/s41467-025-56270-6

Products & Services: Gene Fragments

Massively parallel variant-to-function mapping determines functional regulatory variants of non-small cell lung cancer

Authors: Congcong Chen, Yang Li, Yayun Gu, Qiqi Zhai, Songwei Guo, Jun Xiang, Yuan Xie, Mingxing An, Chenmeijie Li, Na Qin, Yanan Shi, Liu Yang, Jun Zhou, Xianfeng Xu, Ziye Xu, Kai Wang, Meng Zhu, Yue Jiang, Yuanlin He, Jing Xu, Rong Yin, Liang Chen, Lin Xu, Juncheng Dai, Guangfu Jin, Zhibin Hu, Cheng Wang, Hongxia Ma, Hongbing Shen

Journal: Nature Communications

PubMed ID: 39910069

Doi: 10.1038/s41467-025-56725-w

Products & Services: Gene Synthesis

Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses

Authors: Cheng-Bao Ma, Chen Liu, Young-Jun Park, Jingjing Tang, Jing Chen, Qing Xiong, Jimin Lee, Cameron Stewart, Daniel Asarnow, Jack Brown, M Alejandra Tortorici, Xiao Yang, Ye-Hui Sun, Yuan-Mei Chen, Xiao Yu, Jun-Yu Si, Peng Liu, Fei Tong, Mei-Ling Huang, Jing Li, Zheng-Li Shi, Zengqin Deng, David Veesler, Huan Yan

Journal: Cell

PubMed ID: 39922191

Doi: 10.1016/j.cell.2024.12.031

Products & Services: Codon Optimization