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Enhancing mRNA translation efficiency by introducing sequence optimized AU-rich elements in 3′ UTR via HuR anchorage
Authors: Xinghuan Ma , Sujia Liu , Bangda Fan , Danni Jin , Lei Miao , Lin Liu , Shubo Du , Jiaqi Lin
Journal: Mol Ther Nucleic Acids
PubMed ID: 40125272
Doi: doi.org/10.1016/j.omtn.2025.102485
Products & Services: Gene Synthesis   
Controllable intein splicing and N-terminal cleavage at mesophilic temperatures
Authors: Taylor A McNeal, Joel Weinberger, Geraldy L S Liman, Tia M Ariagno, David W Wood, Thomas J Santangelo, Christopher W Lennon
Journal: Front Bioeng Biotechnol
PubMed ID: 39991137
Doi: 10.3389/fbioe.2025.1543573
Products & Services: Gene Synthesis   Mutagenesis Services   
Structural and mechanistic insights into the activation of a short prokaryotic argonaute system from archaeon Sulfolobus islandicus
Authors: Zhikang Dai, Yu Chen, Zeyuan Guan, Xueting Chen, Keyi Tan, Kaiyue Yang, Xuhui Yan, Yidong Liu, Zhou Gong, Wenyuan Han, Tingting Zou
Journal: Nucleic Acids Res
PubMed ID: 39898546
Doi: 10.1093/nar/gkaf059
Products & Services: Gene Synthesis   
Molecular determinants of cross-strain influenza A virus recognition by αβ T cell receptors
Authors: Sergio M Quiñones-Parra, Stephanie Gras, Thi H O Nguyen, Carine Farenc, Christopher Szeto, Louise C Rowntree, Priyanka Chaurasia, Sneha Sant, Adrianus C M Boon, Dhilshan Jayasinghe, Guus F Rimmelzwaan, Jan Petersen, Peter C Doherty, Adam P Uldrich, Dene R Littler, Jamie Rossjohn, Katherine Kedzierska
Journal: Science immunology
PubMed ID: 39919196
Doi: 10.1126/sciimmunol.adn3805
Products & Services: Peptide Synthesis   
Structure of the tilapia lake virus nucleoprotein bound to RNA
Authors: Benoît Arragain, Martin Pelosse, Karine Huard, Stephen Cusack
Journal: Nucleic Acids Res
PubMed ID: 39995042
Doi: 10.1093/nar/gkaf112
Products & Services: Codon Optimization   
Bacteria encode post-mortem protein catabolism that enables altruistic nutrient recycling
Authors: Savannah E R Gibson, Isabella Frost, Stephen J Hierons, Tessa Moses, Wilson C K Poon, Stuart A West, Martin J Cann
Journal: Nature Communications
PubMed ID: 39948360
Doi: 10.1038/s41467-025-56761-6
Products & Services: Gene Synthesis   
Genetic regulation of TERT splicing affects cancer risk by altering cellular longevity and replicative potential
Authors: Oscar Florez-Vargas, Michelle Ho, Maxwell H Hogshead, Brenen W Papenberg, Chia-Han Lee, Kaitlin Forsythe, Kristine Jones, Wen Luo, Kedest Teshome, Cornelis Blauwendraat, Kimberly J Billingsley, Mikhail Kolmogorov, Melissa Meredith, Benedict Paten, Raj Chari, Chi Zhang, John S Schneekloth, Mitchell J Machiela, Stephen J Chanock, Shahinaz M Gadalla, Sharon A Savage, Sam M Mbulaiteye, Ludmila Prokunina-Olsson
Journal: Nature Communications
PubMed ID: 39956830
Doi: 10.1038/s41467-025-56947-y
Products & Services: Custom Vector Construction   
CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair
Authors: Feng Li, Tianpeng Zhang, Aleem Syed, Amira Elbakry, Noella Holmer, Huy Nguyen, Sirisha Mukkavalli, Roger A Greenberg, Alan D D'Andrea
Journal: Nature Communications
PubMed ID: 39962076
Doi: 10.1038/s41467-025-56834-6
Products & Services: CRISPR Plasmids   
RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer
Authors: Zachary Sethna, Pablo Guasp, Charlotte Reiche, Martina Milighetti, Nicholas Ceglia, Erin Patterson,on Jay Lihm, George Payne, Olga Lyudovyk, Luis A Rojas, Nan Pang, Akihiro Ohmoto, Masataka Amisaki, Abderezak Zebboudj, Zagaa Odgerel, Emmanuel M Bruno, Siqi Linsey Zhang, Charlotte Cheng, Yuval Elhanati, Evelyna Derhovanessian, Luisa Manning, Felicitas Müller, Ina Rhee, Mahesh Yad,av Taha Merghoub, Jedd D Wolchok, Olca Basturk, Mithat Gönen, Andrew S Epstein, Parisa Momtaz, Wungki Park, Ryan Sugarman, Anna M Varghese, Elizabeth Won, Avni Desai, Alice C Wei, Michael I D'Angelica, T Peter Kingham, Kevin C Soares, William R Jarnagin, Jeffrey Drebin, Eileen M O'Reilly, Ira Mellman, Ugur Sahin, Özlem Türeci, Benjamin D Greenbaum, Vinod P Balachandran
Journal: Nature
PubMed ID: 39972124
Doi: 10.1038/s41586-024-08508-4
Products & Services: Peptide Synthesis   
Cooperative nutrient scavenging is an evolutionary advantage in cancer
Authors: Gizem Guzelsoy, Setiembre D Elorza, Manon Ros, Logan T Schachtner, Makiko Hayashi, Spencer Hobson-Gutierrez, Parker Rundstrom, Julia S Brunner, Ray Pillai, William E Walkowicz, Lydia W S Finley, Maxime Deforet, Thales Papagiannakopoulos, Carlos Carmona-Fontaine
Journal: Nature
PubMed ID: 39972131
Doi: 10.1038/s41586-025-08588-w
Products & Services: Peptide Synthesis   
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