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Modified pegRNAs mitigate scaffold-derived prime editing by-products

Authors: Panagiotis Antoniou, Louis Dacquay, Hanna Mårtensson, Katja Madeyski-Bengtson, Anna-Lena Loyd, Anna Shiriaeva, Euan Gordon, Salman Mustfa, George Thom, Pei-Pei Hsieh, Saša Šviković, Mike Firth, Nina Akrap, Marcello Maresca & Martin Peterka

Journal: Nature Communications

PubMed ID: 40204736

Doi: 10.1038/s41467-025-58653-1

Products & Services: Gene Synthesis

Structural basis for allosteric modulation of M. tuberculosis proteasome core particle

Authors: Madison Turner, Adwaith B. Uday, Algirdas Velyvis, Enrico Rennella, Natalie Zeytuni & Siavash Vahidi

Journal: Nature Communications

PubMed ID: 40169579

Doi: 10.1038/s41467-025-58430-0

Products & Services: Peptide Synthesis

CodonTransformer: a multispecies codon optimizer using context-aware neural networks

Authors: Adibvafa Fallahpour, Vincent Gureghian, Guillaume J. Filion, Ariel B. Lindner & Amir Pandi

Journal: Nature Communications

PubMed ID: 40180930

Doi: 10.1038/s41467-025-58588-7

Products & Services: Molecular Biology Tools

Vibrio MARTX toxin binding of biantennary N-glycans at host cell surfaces

Authors: Jiexi Chen, Felix Goerdeler, Thapakorn Jaroentomeechai, Francisco X S Hernandez, Xiaozhong Wang, Henrik Clausen, Yoshiki Narimatsu, Karla J F Satchell

Journal: SCIENCE ADVANCES

PubMed ID: 40203092

Doi: 10.1126/sciadv.adt0063

Products & Services: Catalog Antibodies

Using Regular Porous Membrane-Based Blood−Brain Barrier Model to Screen Brain-Targeted Drugs with Nanochannel Electrochemistry

Authors: Yafeng Wu，Zixuan Chen，Fengxiang Chen，Juan Su，Jianyu Han，Songqin Liu

Journal: Anal Chem

PubMed ID: 40183921

Doi: 10.1021/acs.analchem.5c00365

Products & Services: Peptide Synthesis

Molecular mechanisms of the viral encoded chaperone 100K in capsid folding and assembly of adenovirus

Authors: Haining Li , Luyuan Shao , Zhe Liu , Qi Liu , Ye Xiang

Journal: Nat Commun

PubMed ID: 40301360

Doi: 10.1038/s41467-025-59301-4

Products & Services: Protein and Antibody Isolation

Molecular determinants for the association of human hormone-sensitive lipase with lipid droplets

Authors: Han Peng, Qikui Xu, Ting Zhang, Jiakai Zhu, Jinheng Pan, Xiaoyu Guan, Shan Feng, Jianping Wu, Qi Hu

Journal: nature COMMUNICATION

PubMed ID: 40221426

Doi: 10.1038/s41467-025-58887-z

Products & Services: Protein and Antibody Isolation

Self-oxygenating nanoplatform integrating CRISPR/Cas9 gene editing and immune activation for highly efficient photodynamic therapy

Authors: Shi-Cheng Tian, Xun-Huan Song, Ke-Ke Feng, Cheng-Lei Li, Yi-Fan Tu, Yong-Shan Hu, Jing-Wei Shao

Journal: Journal of colloid and interface science

PubMed ID: 40262200

Doi: 10.1016/j.jcis.2025.137632

Products & Services: Synthetic Guide RNA

Shigella effector IpaH1.4 subverts host E3 ligase RNF213 to evade antibacterial immunity

Authors: Xindi Zhou, Huijing Zhang, Yaru Wang, Danni Wang, Zhiqiao Lin, Yuchao Zhang, Yubin Tang, Jianping Liu, Yu-Feng Yao, Yixiao Zhang & Lifeng Pan

Journal: Nature Communications

PubMed ID: 40164614

Doi: 10.1038/s41467-025-58432-y

Products & Services: Protein Electrophoresis and Western

Intranasal influenza virus-vectored vaccine offers protection against clade 2.3.4.4b H5N1 infection in small animal models

Authors: Ying Liu, Shaofeng Deng, Shuang Ren, Rachel Chun-Yee Tam, Siwen Liu, Anna Jinxia Zhang, Kelvin Kai-Wang To, Kwok-Yung Yuen, Honglin Chen & Pui Wang

Journal: Nature Communications

PubMed ID: 40169649

Doi: 10.1038/s41467-025-58504-z

Products & Services: Peptide Synthesis