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Rescue of secretion of a rare-disease associated mis-folded mutant glycoprotein in knock-out mammalian cells

Authors: Gábor Tax, Kevin P Guay, Tatiana Soldà, Charlie J Hitchman, Johan C Hill, Snežana Vasiljević, Andrea Lia, Carlos P Modenutti, Kees R Straatman, Angelo Santino, Maurizio Molinari, Nicole Zitzmann, Daniel N Hebert, Pietro Roversi, Marco Trerotola

Journal: biorxiv

PubMed ID: 37398215

Doi: 10.1101/2023.05.30.542711

Products & Services: Protein and Antibody Isolation

The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis

Authors: Jennilee M Davidson, Sharlynn S L Wu, Stephanie L Rayner, Flora Cheng, Kimberley Duncan, Carlo Russo, Michelle Newbery, Kunjie Ding, Natalie M Scherer, Rachelle Balez, Alberto García-Redondo, Alberto Rábano, Livia Rosa-Fernandes, Lezanne Ooi, Kelly L Williams, Marco Morsch, Ian P Blair, Antonio Di Ieva, Shu Yang, Roger S Chung, Albert Lee

Journal: Mol Neurobiol

PubMed ID: 37243816

Doi: 10.1007/s12035-023-03355-2

Products & Services: Protein and Antibody Isolation

Functionalized Metal–Organic Framework-Modified Hydrogel That Breaks the Vicious Cycle of Inflammation and ROS for Repairing of Diabetic Bone Defects

Authors: An Lao, Jiaqing Wu, Dejian Li, Aili Shen, Yaxin Li, Yu Zhuang, Kaili Lin, Jianyong Wu, Jiaqiang Liu

Journal: Small

PubMed ID: 37183293

Doi: smll.202206919

Products & Services: Protein and Antibody Isolation

Co-delivery of Cas9 mRNA and guide RNAs edits hepatitis B virus episomal and integration DNA in mouse and tree shrew models

Authors: Junzhu Yi, Xinlin Lei, Fangteng Guo, Qiubing Chen, Xueyong Chen, Kaitao Zhao, Chengliang Zhu, Xiaoming Cheng, Jiangwei Lin, Hao Yin, Yuchen Xia

Journal: Antiviral research

PubMed ID: 37142191

Doi: 10.1016/j.antiviral.2023.105618

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Immunogenic SARS-CoV-2 S and N Protein Peptide and Cytokine Combinations as Biomarkers for Early Prediction of Fatal COVID-19

Authors: Ekaterina Martynova , Shaimaa Hamza , Maria Markelova , Ekaterina Garanina , Yuriy Davidyuk , Venera Shakirova , Neha Kaushal , Manoj Baranwal , Robert J Stott-Marshall , Toshana L Foster , Albert Rizvanov , Svetlana Khaiboullina

Journal: Front Immunol .

PubMed ID: 35386707

Doi: 10.3389/fimmu.2022.830715

Products & Services: Peptide Synthesis

In vitro reconstitution of SARS-CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g

Authors: Irina S. Abaeva, Yani Arhab, Anna Miscicka, Christopher U.T. Hellen, and Tatyana V. Pestova

Journal: bioRxiv .

PubMed ID: 37292671

Doi: 10.1101/gad.350829.123

Products & Services: Gene Synthesis

Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response

Authors: Shridhar Bale, Lifei Yang, Mehrdad Alirezaei, Richard Wilson, Takayuki Ota, Esmeralda D Doyle, Christopher A Cottrell, Javier Guenaga, Karen Tran, Wenjuan Li, Leonidas Stamatatos, David Nemazee, Andrew B Ward, Richard T Wyatt

Journal: Front Immunol

PubMed ID: 37283743

Doi: 10.3389/fimmu.2023.1180959

Products & Services: Protein and Antibody Isolation

CFTR and dystrophin encoding plasmids carrying both luciferase reporter gene, nuclear import specific sequences and triple helix sites

Authors: Delphine Maze, Caroline Girardin, Nathalie Benz, Tristan Montier, Chantal Pichon, Patrick Midoux

Journal: Plasmid

PubMed ID: 37207938

Doi: 10.1016/j.plasmid.2023.102686

Products & Services: Protein and Antibody Isolation

Antibody blockade of Jagged1 attenuates choroidal neovascularization

Authors: Torleif Tollefsrud Gjølberg, Jonas Aakre Wik, Hanna Johannessen, Stig Krüger, Nicola Bassi, Panagiotis F Christopoulos, Malin Bern, Stian Foss, Goran Petrovski, Morten C Moe, Guttorm Haraldsen, Johanna Hol Fosse, Bjørn Steen Skålhegg, Jan Terje Andersen, Eirik Sundlisæter

Journal: Nat Commun

PubMed ID: 37253747

Doi: 10.1038/s41467-023-38563-w

Products & Services: Protein and Antibody Isolation

Leveraging a Structural Blueprint to Rationally Engineer the Rieske Oxygenase TsaM

Authors: Jiayi Tian, Alejandro Arcadio Garcia, Patrick H Donnan, Jennifer Bridwell-Rabb

Journal: Biochemistry

PubMed ID: 37188334

Doi: 10.1021/acs.biochem.3c00150

Products & Services: Protein and Antibody Isolation