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Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy

Authors: Stavroula Dionysopoulou, Per Wikstrom, Claudio Bucolo, Giovanni Luca Romano, Vincenzo Micale, Richard Svensson, Dimitris Spyridakos, Niki Mastrodimou, Spiros Georgakis, Panayotis Verginis, Erik Walum, Kyriaki Thermos

Journal: Diabetes

PubMed ID: 36821829

Doi: 10.2337/db22-0515

Products & Services: Protein and Antibody Isolation

The Nucleocapsid Proteins of SARS-CoV-2 and Its Close Relative Bat Coronavirus RaTG13 Are Capable of Inhibiting PKR- and RNase L-Mediated Antiviral Pathways

Authors: Kyle LeBlanc, Jessie Lynch, Christine Layne, Robert Vendramelli, Angela Sloan, Nikesh Tailor, Yvon Deschambault, Fushun Zhang, Darwyn Kobasa, David Safronetz, Yan Xiang, Jingxin Cao

Journal: Microbiol Spectr

PubMed ID: 37154717

Doi: 10.1128/spectrum.00994-23

Products & Services: Protein and Antibody Isolation

Redundant actions of neuropeptides encoded by the dh-pban gene for larval color pattern formation in the oriental armyworm Mythimnaseparata

Authors: Yu Shirai, Hajime Ono, Takaaki Daimon

Journal: Insect Biochem Mol Biol

PubMed ID: 37146697

Doi: 10.1016/j.ibmb.2023.103955

Products & Services: Peptide Synthesis

KRAS mutation-induced TOPK overexpression contributes to tumour progression in non-small cell lung cancer

Authors: Chang Cai, Shuo Yao, Yanmei Zou, Hui Lu, Xiuqiong Chen, Yali Wang, Kun Zheng, Feng Zhu, Yihua Wang, Hua Xiong, Junfei Zhu

Journal: J Cell Mol Med

PubMed ID: 37226642

Doi: 10.1111/jcmm.17640

Products & Services: Protein and Antibody Isolation

Detection of viral RNAs at ambient temperature via reporter proteins produced through the target-splinted ligation of DNA probes

Authors: Elizabeth A Phillips, Adam D Silverman, Aric Joneja, Michael Liu, Carl Brown, Paul Carlson, Christine Coticchia, Kristen Shytle, Alex Larsen, Nadish Goyal, Vincent Cai, Jason Huang, Jennifer E Hickey, Emily Ryan, Joycelynn Acheampong, Pradeep Ramesh, James J Collins, William J Blake

Journal: Nat Biomed Eng

PubMed ID: 37142844

Doi: 10.1038/s41551-023-01028-y

Products & Services: Protein and Antibody Isolation

Design and development of microformulations for rapid release of small molecules and oligonucleotides

Authors: T Brown, M Stanton, F Cros, S Cho, A Kiselyov

Journal: Eur J Pharm Sci

PubMed ID: 37220816

Doi: 10.1016/j.ejps.2023.106472

Products & Services: Protein and Antibody Isolation

Soluble TREM-like Transcript-1 Acts as a Damage-Associated Molecular Pattern through the TLR4/MD2 Pathway Contributing to Immune Dysregulation during Sepsis

Authors: Chia-Ming Chang, Kuang-Hua Cheng, Tsai-Yin Wei, Meng-Ping Lu, Yi-Chen Chen, Yen-Ta Lu

Journal: J Immunol

PubMed ID: 36961438

Doi: 10.4049/jimmunol.2200222

Products & Services: Protein and Antibody Isolation

Modeling cell-mediated immunity in human type 1 diabetes by engineering autoreactive CD8 T cells

Authors: Leeana D Peters, Wen-I Yeh, Juan M Arnoletti, Matthew E Brown, Amanda L Posgai, Clayton E Mathews, Todd M Brusko

Journal: Front Immunol

PubMed ID: 37325626

Doi: 10.3389/fimmu.2023.1142648

Products & Services: Peptide Synthesis

Enhanced stability of the SARS CoV-2 spike glycoprotein following modification of an alanine cavity in the protein core

Authors: Pantelis Poumbourios, Christine Langer, Irene Boo, Tasnim Zakir, Rob J Center, Anouschka Akerman, Vanessa Milogiannakis, Anupriya Aggarwal, Bronte A Johnstone, Jungmin Ha, Fasséli Coulibaly, Stuart G Turville, Heidi E Drummer

Journal: PLoS Pathog

PubMed ID: 37200378

Doi: 10.1371/journal.ppat.1010981

Products & Services: Protein and Antibody Isolation

saRNA vaccine expressing membrane-anchored RBD elicits broad and durable immunity against SARS-CoV-2 variants of concern

Authors: Mai Komori, Takuto Nogimori, Amber L Morey, Takashi Sekida, Keiko Ishimoto, Matthew R Hassett, Yuji Masuta, Hirotaka Ode, Tomokazu Tamura, Rigel Suzuki, Jeff Alexander, Yasutoshi Kido, Kenta Matsuda, Takasuke Fukuhara, Yasumasa Iwatani, Takuya Yamamoto, Jonathan F Smith, Wataru Akahata

Journal: Nat Commun

PubMed ID: 37208330

Doi: 10.1038/s41467-023-38457-x

Products & Services: Protein and Antibody Isolation