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页码: 358/5154 每页显示数量
Deep sampling of gRNA in the human genome and deep-learning-informed prediction of gRNA activities
Authors: Heng Zhang, Jianfeng Yan, Zhike Lu, Yangfan Zhou, Qingfeng Zhang, Tingting Cui, Yini Li, Hui Chen, Lijia Ma
Journal: Cell Discov
PubMed ID: 37193681
Doi: 10.1038/s41421-023-00549-9
Products & Services: Gene Synthesis   
Conserved cardiolipin-mitochondrial ADP/ATP carrier interactions assume distinct structural and functional roles that are clinically relevant
Authors: Nanami Senoo, Dinesh K Chinthapalli, Matthew G Baile, Vinaya K Golla, Bodhisattwa Saha, Oluwaseun B Ogunbona, James A Saba, Teona Munteanu, Yllka Valdez, Kevin Whited, Dror Chorev, Nathan N Alder, Eric R May, Carol V Robinson, Steven M Claypool
Journal: biorxiv
PubMed ID: 37205478
Doi: 10.1101/2023.05.05.539595
Products & Services: Molecular Biology Reagents   
Inflammation Modifies miR-21 Expression Within Neuronal Extracellular Vesicles to Regulate Remyelination Following Spinal Cord Injury
Authors: Tianyu Han, Peiwen Song, Zuomeng Wu, Yunlei Liu, Wang Ying, Cailiang Shen
Journal: Stem Cell Rev Rep
PubMed ID: 37256514
Doi: 10.1007/s12015-023-10560-y
Products & Services: Gene Synthesis   
GSK3 phosphorylates and regulates the Green Revolution protein Rht-B1b to reduce plant height in wheat
Authors: Huixue Dong, Danping Li, Ruizhen Yang, Lichao Zhang, Yunwei Zhang, Xu Liu, Xiuying Kong, Jiaqiang Sun
Journal: Plant Cell
PubMed ID: 36945740
Doi: 10.1093/plcell/koad090
Products & Services: Recombinant Proteins   
Deep learning models to predict the editing efficiencies and outcomes of diverse base editors
Authors: Nahye Kim, Sungchul Choi, Sungjae Kim, Myungjae Song, Jung Hwa Seo, Seonwoo Min, Jinman Park, Sung-Rae Cho, Hyongbum Henry Kim
Journal: Nat Biotechnol
PubMed ID: 37188916
Doi: 10.1038/s41587-023-01792-x
Products & Services: Gene Synthesis   
A highly efficient transgene knock-in technology in clinically relevant cell types
Authors: Alexander G Allen, Samia Q Khan, Carrie M Margulies, Ramya Viswanathan, Swarali Lele, Laura Blaha, Sean N Scott, Kaitlyn M Izzo, Alexandra Gerew, Rithu Pattali, Nadire R Cochran, Carl S Holland, Amy H Zhao, Stephen E Sherman, Michael C Jaskolka, Meng Wu, Aaron C Wilson, Xiaoqi Sun, Dawn M Ciulla, Deric Zhang, Jacqueline D Nelson, Peisheng Zhang, Patrizia Mazzucato, Yan Huang, Georgia Giannoukos, Eugenio Marco, Michael Nehil, John A Follit, Kai-Hsin Chang, Mark S Shearman, Christopher J Wilson, John A Zuris
Journal: Nat Biotechnol
PubMed ID: 37127662
Doi: 10.1038/s41587-023-01779-8
Products & Services: Gene Synthesis   
Structure of a 10-23 Deoxyribozyme Exhibiting a Homodimer Conformation
Authors: Evan Cramer, Sarah Starcovic, Rebekah Avey, Ali Kaya, Aaron Robart
Journal: Res Sq
PubMed ID: 37398199
Doi: 10.21203/rs.3.rs-2252941/v1
Products & Services: Gene Synthesis   
Functionalized Metal–Organic Framework-Modified Hydrogel That Breaks the Vicious Cycle of Inflammation and ROS for Repairing of Diabetic Bone Defects
Authors: An Lao, Jiaqing Wu, Dejian Li, Aili Shen, Yaxin Li, Yu Zhuang, Kaili Lin, Jianyong Wu, Jiaqiang Liu
Journal: Small
PubMed ID: 37183293
Doi: smll.202206919
Products & Services: Protein and Antibody Isolation   
Co-delivery of Cas9 mRNA and guide RNAs edits hepatitis B virus episomal and integration DNA in mouse and tree shrew models
Authors: Junzhu Yi, Xinlin Lei, Fangteng Guo, Qiubing Chen, Xueyong Chen, Kaitao Zhao, Chengliang Zhu, Xiaoming Cheng, Jiangwei Lin, Hao Yin, Yuchen Xia
Journal: Antiviral research
PubMed ID: 37142191
Doi: 10.1016/j.antiviral.2023.105618
Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)   
Immunogenic SARS-CoV-2 S and N Protein Peptide and Cytokine Combinations as Biomarkers for Early Prediction of Fatal COVID-19
Authors: Ekaterina Martynova , Shaimaa Hamza , Maria Markelova , Ekaterina Garanina , Yuriy Davidyuk , Venera Shakirova , Neha Kaushal , Manoj Baranwal , Robert J Stott-Marshall , Toshana L Foster , Albert Rizvanov , Svetlana Khaiboullina
Journal: Front Immunol .
PubMed ID: 35386707
Doi: 10.3389/fimmu.2022.830715
Products & Services: Peptide Synthesis   
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