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MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity

Authors: Thilini S Munasinghe, Megan R Edwards, Sofiya Tsimbalyuk, Olivia A Vogel, Kate M Smith, Murray Stewart, Justin K Foster, Loretta A Bosence, David Aragão, Justin A Roby, Christopher F Basler, Jade K Forwood

Journal: Nat Commun

PubMed ID: 35338144

Doi: 10.1038/s41467-022-28851-2

Products & Services: Bacterial Expression

Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer

Authors: Andrea Lopez, Denis E Reyna, Nadege Gitego, Felix Kopp, Hua Zhou, Miguel A Miranda-Roman, Lars Ulrik Nordstrøm, Swathi-Rao Narayanagari, Ping Chi, Eduardo Vilar, Aristotelis Tsirigos, Evripidis Gavathiotis

Journal: Nat Commun

PubMed ID: 35256598

Doi: 10.1038/s41467-022-28741-7

Products & Services: Catalog Peptides

The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal β-hairpin and induces neutrophil migration as a selective CXCR2 agonist

Authors: Christian Berg, Michael J Wedemeyer, Motiejus Melynis, Roman R Schlimgen, Lasse H Hansen, Jon Våbenø, Francis C Peterson, Brian F Volkman, Mette M Rosenkilde, Hans R Lüttichau

Journal: PLoS Pathog

PubMed ID: 35271688

Doi: 10.1371/journal.ppat.1010355

Products & Services: Custom Vector Construction

Diagnostic Host Gene Expression Analysis by Quantitative Reverse Transcription Loop-Mediated Isothermal Amplification to Discriminate between Bacterial and Viral Infections

Authors: Melissa C Remmel, Sabrina M Coyle, Mark W Eshoo, Timothy E Sweeney, David C Rawling

Journal: Clin Chem

PubMed ID: 35134876

Doi: 10.1093/clinchem/hvab275

Products & Services: Mammalian Expression

A novel series of putative Brugia malayi histone demethylase inhibitors as potential anti-filarial drugs

Authors: Tamara Kreiss, Tyler Eck, Brittany Hart, Sreedhar Tummalapalli, David Rotella, John Siekierka

Journal: PLoS Negl Trop Dis

PubMed ID: 35294431

Doi: 10.1371/journal.pntd.0010216

Products & Services: Custom Vector Construction

Performance of Chimeric Antigens in Serological Screening for Chagas Disease in Blood Banks

Authors: Emily Ferreira Dos Santos, Ângelo Antônio Oliveira Silva, Natália Erdens Maron Freitas, Leonardo Maia Leony, Ramona Tavares Daltro, Carlos Antônio de Souza Teles Santos, Maria da Conceição Chagas de Almeida, Fernando Luiz Vieira de Araújo, Paola Alejandra Fiorani Celedon, Marco Aurélio Krieger, Nilson Ivo Tonin Zanchin, Mitermayer Galvão Dos Reis, Fred Luciano Neves Santos

Journal: Front Med (Lausanne)

PubMed ID: 35330587

Doi: 10.3389/fmed.2022.852864

Products & Services: Custom Vector Construction

Sequence-specific destabilization of azurin by tetramethylguanidinium-dipeptide ionic liquids

Authors: Roshani Patel, Austin K Clark, Gabriella DeStefano, Isabella DeStefano, Hunter Gogoj, Erin Gray, Aashka Y Patel, Joshua T Hauner, Gregory A Caputo, Timothy D Vaden

Journal: Biochem Biophys Rep

PubMed ID: 35280523

Doi: 10.1016/j.bbrep.2022.101242

Products & Services: Bacterial Expression

The protective effects of butorphanol tartrate against homocysteine-induced blood-brain barrier dysfunction

Authors: Sufeng Shen, Jiandong Wang, Qingyuan Zhao, Qiangfu Hu

Journal: Bioengineered

PubMed ID: 35245993

Doi: 10.1080/21655979.2022.2037953

Products & Services: Gene Synthesis

Pull-Down Into Active Inclusion Bodies and Their Application in the Detection of (Poly)-Phosphates and Metal-Ions

Authors: Eva Hrabarova, Martina Belkova, Romana Koszagova, Jozef Nahalka

Journal: Front Bioeng Biotechnol

PubMed ID: 35299638

Doi: 10.3389/fbioe.2022.833192

Products & Services: Gene Synthesis

TFPIisacoloniccryptreceptorforTcdBfromhypervirulentclade2C.difficile

Authors: Jianhua Luo , Qi Yang , Xiaofeng Zhang , Yuanyuan Zhang , Li Wan , Xiechao Zhan , Yao Zhou , Liuqing He , Danyang Li , Dazhi Jin , Ying Zhen , Jing Huang , Yanyan Li , Liang Tao

Journal: Cell

PubMed ID: 35303428

Doi: 10.1016/j.cell.2022.02.010

Products & Services: Codon Optimization