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页码: 1/5149 每页显示数量

Cynarin as a potent anti‑osteolytic agent: Targeting MAPK and Nrf2‑Keap1 pathways for osteoclast inhibition and bone protection

Authors: Rui Chao, Yexin Wang, Zhan Liu, Tianhao Wan, Yi Mao, Xinru Xie, Lei Sun, Weifeng Xu, Xuzhuo Chen, Shanyong Zhang

Journal: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

PubMed ID: PMC12488209

Doi: 10.3892/ijmm.2025.5647

Products & Services: Proteins, Expression, Isolation and Analysis

Engineered ipilimumab variants that bind human and mouse CTLA-4

Authors: Brett Robison 1, S J Diong 1, Anusha Kumar 1, Thomas M Moon , Olin Chang , Bryant Chau , Christine Bee , Ishita Barman , Arvind Rajpal , Alan J Korman , Sean West , Pavel Strop , Peter S Lee

Journal: MAbs

PubMed ID: 39849917

Doi: 10.1080/19420862.2025.2451296

Products & Services: Combinatorial DNA Libraries

A novel low-cost and sensitive electrochemical biosensor based on Yb-protein/GO/SPE for rare earth element detection

Authors: Ting Zhang, Danni Ma, Jiaxing Gong, Bolun Sun, Fuman Cai

Journal: Sustainable Chemistry and Pharmacy

Doi: doi.org/10.1016/j.scp.2025.102248

Products & Services: Molecular Biology Reagents

De novo designed voltage-gated anion channels suppress neuron firing

Authors: Chen Zhou, Huican Li, Jiaxing Wang, Cheng Qian, Hui Xiong, Zhilin Chu, Qiming Shao, Xuan Li, Shijin Sun, Ke Sun, Aiqin Zhu, Jiawei Wang, Xueqin Jin, Fan Yang, Tamer M Gamal El-Din, Bo Li, Jing Huang, Kun Wu, Peilong Lu

Journal: Cell

PubMed ID: 41106381

Doi: 10.1016/j.cell.2025.09.023

Products & Services: Proteins, Expression, Isolation and Analysis

Journal of Controlled Release

Authors: Fei Li, Quan Wang, Tingting Wang, Chen Xiong, Ziling Chen, Hanzhi Ouyang, Xiaoding Lou, Fan Xia, Shixuan Wang, Meng Wu, Jun Dai

Journal: Journal of controlled release

Doi: 10.1016/j.jconrel.2025.114337

Products & Services: Plasmid DNA Preparation

Discovery of a Serine-Directed Chemical Reaction for Site-Specific Protein Modification via Phage Display Screening

Authors: Yingjie Lei, Kai Zhao, Mengzhun Guo, Liang Guo, Jinfeng Chen, Mengjiao Li, Dandan Liu, Kai Chen, Jiahao Mei, Tian Li, Bing Yang, Jing Huang, Bobo Dang

Journal: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PubMed ID: 41108661

Doi: doi.org/10.1002/anie.202514412

Products & Services: Proteins, Expression, Isolation and Analysis

Metabolic Hijacking by Engineered Probiotics Reprograms Tumor Metabolism and Immune Microenvironment for Self-Reinforcing Photodynamic Immunotherapy

Authors: Shurong Qin, Qi Wang, Zhuangwei Zhang, Junhui Gu, Guanzhong He, Fei Zeng, Ruiyue Chen, Bangshun He, Yuzhen Wang, Meng Wang, Yujun Song

Journal: Journal of the American Chemical Society

PubMed ID: 41059938

Doi: 10.1021/jacs.5c10242

Products & Services: Recombinant Proteins

ZBP1 pathway promotes tumor immunogenicity in thecombinationofanti-HER2therapyandepigenetic therapy

Authors: Qishan Wang, Zhihao Wu, Yuanqin Yang, Chao Yang, Haoran Deng, Xingyue Zhou, Shuting Xu, Lingling Wu, Xiaochuan Hong, Xueni Yu, Lu Lu, Liufu Deng

Journal: Cell Reports

Doi: 10.1016/j.celrep.2025.116314

Products & Services: Proteins, Expression, Isolation and Analysis

Integration of humanized ROBO1 CAR in PD-1 locus in natural killer cells delivers synergistic tumor-killing effect against nonsmall cell lung cancer

Authors: Jia-Hao Tao, Jun Zhang, Chun-Yan Tang, Jia-Xi Duan, Wen-Jing Zhong, Chen-Yu Zhang, Yu-Biao Liu, Jin Ling, Hua-Shun Li, Yong Zhou, Cha-Xiang Guan

Journal: Cancer gene therapy

PubMed ID: 40913086

Doi: 10.1038/s41417-025-00957-x

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

The EP300-Targeting Drug CCS1477 Inhibits the Growth and Development of Diffuse Large B-Cell Lymphoma by Promoting Apoptosis and Mitophagy to Reduce Drug Resistance

Authors: Rujia Si, Yihan Zhang, Bowen Hu, Yuxin Du, Dan Zou, Shaodi Wen, Xiaoyue Du, Xin Chen, Chen Peng, Shulei Fu, Shiying Zhu, Fan Du, Xiaofeng Sha, Ning Ding, Cong Xu, Bo Shen

Journal: Anti-Cancer Agents in Medicinal Chemistry

Doi: 10.2174/0118715206430859250915050817

Products & Services: Proteins, Expression, Isolation and Analysis

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