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Transcription remodeling and stalling by cisplatin-induced interstrand crosslinks

Authors: Liulian Zhu, Weiqi Zhao, Lei Ye, Yankai Liu, Wenjing Deng, Bingshuo Qian, Xin Yang, Jun Xu

Journal: Nature Chemical Biology

PubMed ID: 42827153

Doi: 10.1038/s41589-026-02338-3

Products & Services: Custom DNA/RNA Oligos

Chemoreceptor TRPγ coordinates locomotor activity via regulating intracellular Ca2+ homeostasis in Drosophila

Authors: Peiyuan Pang, Bomin Gao, Xiaoyi Mo, Xuteng Lu, Xiang Li, Peiyu Wang, Qiong Shi, Keyu Xia, Panhao Xiao, Hongcun Gai, Chang Xie, Dongdong Li, Demeng Sun, Changlin Tian, Jing Yao

Journal: Nature Communications

Doi: 10.1038/s41467-026-78915-w

Products & Services: Protein and Antibody Isolation

Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic cancer: the randomized phase 2 AMPLIFY-7P trial

Authors: Ben George, Harshabad Singh, Craig E. Devoe, Vincent Chung, Peter J. Hosein, Andrew Hendifar, Dae Won Kim, Jennifer B. Valerin, Tanios Bekaii-Saab, Dana B. Cardin, Manuel Hidalgo, Pashtoon M. Kasi, Alexis D. Leal, Meredith Pelster, Naomi Fei, Colin D. Weekes, Mark H. O’Hara, Thomas J. George, Syed M. Kazmi, Jonathan D. Mizrahi, Suresh Nair, Martin Maiers, Thian Kheoh, Gianni Amato, Jino Xavier, Julia P. Snyder, Madison H. Milaszewski, Xavier Cabana-Puig, James R. Perry, Lisa K. McNeil, Esther Welkowsky, Peter C. DeMuth, Christopher M. Haqq, Shubham Pant, Zev A. Wainberg, Eileen M. O’Reilly

Journal: nature medicine

PubMed ID: 42919966

Doi: 10.1038/s41591-026-04734-7

Products & Services: Peptide Synthesis

Macrophage- or neutrophil-expressed UPP1 drives tumor growth and immune suppression in the tumor microenvironment

Authors: Yin Li, Qin Ran, Anying Xiong, Manling Jiang, Fengkai Xu, Yongqi Wei, Jie Gu, Guoping Li, Di Ge, Chunlai Lu

Journal: Science advences

PubMed ID: 42873856

Doi: 10.1126/sciadv.aea8798

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Thioredoxin-2 Alleviates Osteoporosis by Restraining FOXO3a Nuclear Translocation

Authors: Chi Zhan, Zhaocai Zhou, Yue Ding, Rong Lian, Xinyu Li, Xintong Zhang, Jie Cao, Zhonghui Tang, Zhengmei Lin, Zhi Song, Feng He

Journal: Advanced Science

PubMed ID: 42893445

Doi: 10.1002/advs.78304

Products & Services: Gene Synthesis

CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells

Authors: Zhuoshuo Xu, Xinyu Zhang, Fang Dong, Nenghao Shen, Jun Zhou, Zihan Xi, Zhenghao Wu

Journal: Advanced Science

PubMed ID: 42829916

Doi: 10.1002/advs.78088

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Human-specific morphoregulatory signatures in basal radial glia characterise neocortex evolution

Authors: Theresa M Schütze, Annika Kolodziejczyk, Nora Ditzer, Silvia Vangelisti, Emanuele Capra, Jeong-Eun Lee, Ilaria Chiaradia, Vida Kufrin, Seiya Yamada, Jula Peters, Maximilian Krause, Christina Eugster Oegema, Razvan P Derihaci, Cahit Birdir, Takashi Namba, Alexander A Wurm, Ulrich Martin, Pauline Wimberger, Katherine R Long, Madeline A Lancaster, Nereo Kalebic, Boyan Bonev, Mareike Albert

Journal: Nature Communications

PubMed ID: 42855494

Doi: 10.1038/s41467-026-78474-0

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Global and specific mechanisms stimulate mistranslation in cancer

Authors: Demi Wernaart, Amos Fumagalli, Mrittika Adhikary, Xiaodong Feng, Olaf Geintzer, Edwin S Kyei-Baffour, Onno B Bleijerveld, Liesbeth Hoekman, Ceri Zwart, Alexander Fish, Lisanne Giebel, Artur Burylo, Natalie Proost, Pierre-René Körner, Ferhat Alkan, Chao Yang, Janne Brouwer, Cecilia Anna Henriksen, Eric Westhof, Julien Champagne, Olaf van Tellingen, Marina Rodnina, Reuven Agami

Journal: Nature Cell Biology

PubMed ID: 42834166

Doi: 10.1038/s41556-026-02088-3

Products & Services: Peptide Synthesis

Spectral tuning and signaling of diverse and far red–sensitive rhodopsins in mantis shrimp eyes

Authors: Camille Brouillon, Alina Pushkarev, Marjorie A Liénard, Songhwan Hwang, Arno Munhoven, Richard McDowell, Robert J Lucas, Megan Porter, Han Sun, Peter Hegemann

Journal: Science advences

PubMed ID: 42873850

Doi: 10.1126/sciadv.aef5666

Products & Services: Peptide Synthesis

Sensory receptor expansion and neural accommodation in butterfly color vision

Authors: Ke Gao, Julia Ainsworth, Antoine Donati, Yunchong Zhao, Michelle Franc Ragsac, Cara Genduso, Zoie Andre, Andrew Tomlinson, Michael W Perry

Journal: Science advences

PubMed ID: 42842662

Doi: 10.1126/sciadv.aei7570

Products & Services: Polyclonal Antibody Services