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Cholesterol analogs modulate lipid nanoparticle performance for mRNA delivery after lyophilization and enable ocular disease therapy

Authors: Ting Wang, Wanqi Li, Jianyang Chen, Sitian Cheng, Min Gao, Chengyu Jiang, Chengyu Jiang, Bingyi Hu, Tzu-Cheng Sung, Akon Higuchi

Journal: Materials Today Bio

Doi: 10.1016/j.mtbio.2026.103044

Products & Services: Custom mRNA synthesis

Genome-Wide Identification, Characterization, and Functional Analysis of the GSK3/Shaggy-like Gene Family in Melon (Cucumis melo L.)

Authors: Peng Tian, Bing Li, Jingjing Zhang, Xiurui Gao, Wei Liu, Bowen Liu, Zhaowei Li, Jing Yang, Mengyuan Su, Jige Dang, Yanrong Wu

Journal: Horticulturae

Doi: 10.3390

Products & Services: Gene Synthesis

Diverse binding poses of agonistic neurotoxins on human Nav 1.6

Authors: Xiao Fan, Jian Huang, Lin Yang, Jiaofeng Chen, Huan Wang, Xiaoshuang Huang, Jinli Geng, Qinglin Wu, Yuzhen Xie, Fangzhou Lu, Qinmeng Guo, Zilin Shen, Xueqin Jin, Nieng Yan

Journal: Nature

Doi: 10.1038/s41586-026-10661-x

Gut microbiota-modulated glutamic acid rejuvenates the quality of oocytes deteriorated by advanced reproductive age

Authors: Feixue Wang, Wenjun Zeng, Zihao Zhang, Na Li, Zhaokang Cui, Jie Bai, Jiner Yan, Yu Zhang, Yilong Miao, Ling Gu, Bo Xiong

Journal: EMBO Molecular Medicine

PubMed ID: 42103932

Doi: 10.1038/s44321-026-00443-3

Products & Services: Protein Electrophoresis and Western

Sustained-Release Ulcer-Protective Microarray Patch With Dihydrocapsaicin for Diabetic Wound Regeneration

Authors: Yuxu Wu, Kan Jiang, Xiao Wen, Chihao Jin, Kai Zhang, Jiakai Zhang, Jiale Jin, Jiaqian Wang, Huiyu Hu, Zonghan Xu, Xianzhu Zhang, Yihe Hu

Journal: Exploration

Doi: 10.1002/exp.20250129

Products & Services: Protein Electrophoresis and Western

Genuine Directed Evolution In Test Tube (GENie)

Authors: Lilin Feng; Maochao Mao; Ulrich Schwaneberg

Journal: biorxiv

PubMed ID: 42146629

Doi: 10.64898/2026.05.04.722721

Polypeptides synthesized by common bacteria in the human gut improve rodent metabolism

Authors: Yong Fan; Liwei Lyu; Ruben Vazquez-Uribe; Wanliang Zhang; Mareike Bongers; Andreas Koulouktsis; Mengliu Yang; Vita Sereika-Bejder; Tulika Arora; Evelina Stankevic; Jeremy Armetta; Franziska Zosel; Charlotta D. de la Cour; Lotte Simonsen; Alina Kulakova; Michael Wierer; Pernille Harris; Joachim G de; Peter Rossing; Filip K. Knop; Tune H. Pers; Tue Haldor Hansen; Trine Nielsen; Ling Li; Kristian Str mgaard; Gangyi Yang; Morten Otto Alexander Sommer; Oluf Pedersen

Journal: Nature Microbiology

PubMed ID: 40745048

Doi: 10.1038/s41564-025-02064-x

Polypeptides synthesized by common bacteria in the human gut improve rodent metabolism

Journal: Nature Microbiology

PubMed ID: 40745048

Doi: 10.1038/s41564-025-02064-x

Engineered haptoglobin β fusion protein targets myoglobin and ameliorates rhabdomyolysisassociated acute kidney injury

Authors: Ning Li, Yuru Wang, Lu Han, Ou Qiao, Xinyue Wang, Herui Hao, Xin Chen, Pengtao Wang, Sania Saeed, Jing Wang, Fengjiao Bao, Yingjie Hou, Li Zhang, Xiaohong Duan, Shuquan Rao, Yanhua Gong

Journal: EMBO Molecular Medicine

PubMed ID: 42185634

Doi: 10.1038/s44321-026-00454-0

Products & Services: Synthetic Guide RNA

Stimuli-triggered formation of de novo -designed protein biomaterials

Authors: Nicole E. Gregorio; Zhe Li; Jack W. Hoye; David Baker; Cole A. DeForest

Journal: Cell Biomaterials

PubMed ID: 41909827

Doi: 10.1016/j.celbio.2025.100239