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页码: 1/5152 每页显示数量

Cynarin as a potent anti‑osteolytic agent: Targeting MAPK and Nrf2‑Keap1 pathways for osteoclast inhibition and bone protection

Authors: Rui Chao, Yexin Wang, Zhan Liu, Tianhao Wan, Yi Mao, Xinru Xie, Lei Sun, Weifeng Xu, Xuzhuo Chen, Shanyong Zhang

Journal: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

PubMed ID: PMC12488209

Doi: 10.3892/ijmm.2025.5647

Products & Services: Proteins, Expression, Isolation and Analysis

Engineered ipilimumab variants that bind human and mouse CTLA-4

Authors: Brett Robison 1, S J Diong 1, Anusha Kumar 1, Thomas M Moon , Olin Chang , Bryant Chau , Christine Bee , Ishita Barman , Arvind Rajpal , Alan J Korman , Sean West , Pavel Strop , Peter S Lee

Journal: MAbs

PubMed ID: 39849917

Doi: 10.1080/19420862.2025.2451296

Products & Services: Combinatorial DNA Libraries

Human Substance P Interactions with G Protein-Coupled Receptor NK1R Observed by NMR in Solution

Authors: Haoyi Ge, Lingyun Yang, Changran Chen, Yuxin Xu, Dongsheng Liu, Kurt Wüthrich

Journal: Journal of the American Chemical Society

PubMed ID: 41264783

Doi: doi.org/10.1021/jacs.5c12553

Products & Services: Peptide Synthesis

Early CD4+ T-cell immune reconstitution as a biomarker for Epstein-Barr virus control following allogeneic transplantation

Authors: Kexin Lin, Wenwen Yang, Jiaxiu Yin, Jing Luo, Hao Zhou, Lanxiang Liu, Li Yang, Jie Luo, Lin Liu, Junli Mou

Journal: Blood research

PubMed ID: 41186900

Doi: 10.1007/s44313-025-00106-1

Products & Services: Molecular Biology Reagents

Glutathionylated DNA adducts accumulate in mitochondrial DNA and are regulated by AP endonuclease 1 and tyrosyl-DNA phosphodiesterase 1

Authors: Yu Hsuan Chen, Martin Esparza Sanchez, Ta I Hung, Jin Tang, Wenyan Xu, Jiekai Yin, Yinsheng Wang, Chia-En A Chang, Huimin Zhang, Junjie Chen, Linlin Zhao

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 41259143

Doi: doi.org/10.1073/pnas.2509312122

Products & Services: Catalog Antibody

Engineering Multicellular Inter-communication Systems Using a Synthetic Homodimer-inducible Kinase Receptor

Authors: Quan Zhang, Miao Zhang, Yao Zhang, Fenglin Wang, Jian-Hui Jiang

Journal: Angewandte Chemie (International ed. in English)

PubMed ID: 41267507

Doi: 10.1002/anie.202513254

Products & Services: PCR Cloning and Subcloning DNA Sequencing

Double-stranded DNA deaminase DddAE1347A can increase the efficiency and targeting range of cytidine base editors

Authors: Yuqiang Qian, Fengjiao Hui, Wenchao Niu, Di Wang, Yang Hao, Qingying Meng, Siyu Ren, Deqiang Kong, Heng Gong, Jiayu Wu, Kexin Chen, Muna Alariqi, Junping Gao, Zhanjun Li, Shuangxia Jin

Journal: GENOME BIOLOGY

PubMed ID: 41250247

Doi: 10.1186/s13059-025-03849-3

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Genome-Wide Identification of GW5-LIKE Family Revealed the Function of ClGL1 Involved in Fruit and Seed Shape by Mediating Brassinosteroid Signaling in Watermelon

Authors: Peng Tian, Lei Zhang, Jingjing Zhang, Bowen Liu, Wei Liu, Bing Li, Xiurui Gao, Jie Zhang, Yanrong Wu, Yong Xu

Journal: Horticulturae

Doi: 10.3390

Products & Services: Custom DNA/RNA Oligos

TNC-targeted CAR-macrophage therapy alleviates liver fibrosis in mice

Authors: Kai-Zhao Chen, Zi-Yang Lin, Long-Jun Chen, You-Xi Zhou, Wei Zhang, Hao-Yang Wan, Yong-Kun Huo, Qi Fu, Zi-Qing Gao, Hong-Wei Cheng, Xiao-Dong Ma, Shuai-Shuai Zhang

Journal: Military Medical Research

PubMed ID: 41214839

Doi: 10.1186/s40779-025-00667-3

Products & Services: Proteins, Expression, Isolation and Analysis

Glycosaminoglycans activate peptidylarginine deiminase 4 by enhancing calcium affinity

Authors: Grzegorz P. Bereta， Ewa Bielecka， Karolina Marzec， Łukasz Pijanowski， Artur P. Biela， Piotr Wilk， Marta Kamińska， Jakub Nowak， Elżbieta Wątor-Wilk， Przemysław Grudnik， Dominik Kowalczyk， Joanna Kozieł， Piotr Mydel， Marcin Poręba， Tomasz Kantyka

Journal: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PubMed ID: 41166417

Doi: doi.org/10.1073/pnas.2508369122

Products & Services: Gene Synthesis

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