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Terminal-Overhang-Restricted CRISPR Logic Nanodevice for Precision Cancer Therapy

Authors: Jingge Zhang, Yuhe Yang, Yonghua Wu, Mengyuan Shi, Xinyu Tan, Chengzhi Zhang, Qianqian Ni, Jinjin Wang, Zhenzhong Zhang, Yanan Li, Kaixiang Zhang

Journal: Journal of Controlled Release

PubMed ID: 42833528

Doi: 10.1016/j.jconrel.2026.115433

Products & Services: Protein Electrophoresis and Western

Near-infrared light-ignited hybrid membrane-camouflaged bacterial bombs for bioorthogonal catalysis-boosted tumor pyroptosis

Authors: Uiyue Chen, Qianglan Lu, Zhiyong Liu, Su Zhou, Fei Zeng, Shurong Qin, Yi Yin, Yanfeng Gao, Yuzhen Wang, Meng Wang, Yujun Song

Journal: Acta Pharmaceutica Sinica B

Doi: 10.1016/j.apsb.2026.10.002

Products & Services: Recombinant Proteins

Mapping of pikachurin heparan sulfate modification to a region dispensable for synaptic localization in photoreceptors

Authors: Robyn V McGowan, Faiyaz A K Abid, Melina A Agosto

Journal: f Biological Chemistry Received

PubMed ID: 42906679

Doi: doi.org/10.1016/j.jbc.2026.113632

Products & Services: Protein and Antibody Isolation

Sensory neuron-derived CGRP ameliorates kidney injury and fibrosis via monocytes and macrophages

Authors: Lei Wang, Huaikang Li, Ji Feng, Jianwen Chen, Tongyu Jia, Tailai Zhou, Li Wang, Lu Tang, Xu Zhang, Xin Ma

Journal: Cell Research

PubMed ID: 42918818

Doi: 10.1038/s41422-026-01308-7

Products & Services: Catalog Peptides

Genome-wide analysis of common structural variants in Alzheimer’s disease identifies a risk-associated regulatory CCG repeat in FAM193B

Authors: Han Cao, Yifan Fu, Xiaopu Zhou, Yangyang Duan, Fanny C F Ip, Yu Chen, Shenyuan Hu, Si Chai Liu, Timothy C Y Kwok, Kin Y Mok, Tom H Cheung, John Hardy, Amy K Y Fu, Nancy Y Ip

Journal: Nature neuroscience

PubMed ID: 42864446

Doi: 10.1038/s41593-026-02481-z

Recognition and mechanism of M. tuberculosis cell wall galactan transport

Authors: Chuancun Wei, Katherine A Abrahams, Violetta Krisilia, Jian Li, Sudagar S Gurcha, Eveline Derr, Milena Hänisch, Rainer Kalscheuer, Gurdyal S Besra, Zihe Rao, Lu Zhang

Journal: Nature Communications

PubMed ID: 42850284

Doi: 10.1038/s41467-026-78496-8

Products & Services: Protein and Antibody Isolation

A co-evolved peptide-GPCR system senses host entry to drive fungal infection

Authors: Gabriel Mendoza-Rojas, Philip Nakonz, Min Lu, Nora Marie Kühne, Johannes Postma, Naomi Shtakser, Max Heinen, Manav Patel, Orlando Arguello-Miranda, Kai Heimel, Sonja Billerbeck, Florian Altegoer

Journal: Nature Communications

PubMed ID: 42855465

Doi: 10.1038/s41467-026-78428-6

Products & Services: Chemicals

HECTD1 Directs HIF-1α to Facilitate Intestinal Inflammation and Carcinogenesis via Promoting Th17 Differentiation and Glycolysis

Authors: Shuiyu Xu, Qiaoqiao Han, Feixiang Wang, Yuerong Zhang, Haoran Feng, Kun Liu, Fang Xiu Luo, Fei Yuan, Xuesong Zhao, Xiaoyan Yu, Haiyan Huang, Qiang Zou, Ren Zhao

Journal: Advanced Science

PubMed ID: 42893454

Doi: 10.1002/advs.78339.

Products & Services: Synthetic Guide RNA

Citron kinase activity controls alternative splicing events that drive prostate cancer growth

Authors: Chitra Rawat, Nidhi Singh, Ujjwal R Dahiya, Qiang Hu, Sarah Ng, Dingxiao Zhang, Shaun R Stauffer, Amina Zoubeidi, Eva Corey, Jesse McKenney, Christopher J Weight, Samuel C Haywood, Song Liu, Tao Liu, Hannelore V Heemers

Journal: Science advences

PubMed ID: 42853943

Doi: 10.1126/sciadv.aee5257

Products & Services: Gene Synthesis

Carbonic anhydrase VIII regulates IP3R1-dependent Ca2+ signaling to coordinate insulin secretion and hepatic glucose production

Authors: Muhammad Fauzi, Takaaki Murakami, Ryota Usui, Ainur Botagarova, Daisuke Otani, Kentarou Sakaki, Shinsuke Tokumoto, Toshinori Imaizumi, Hisato Tatsuoka, Masahito Ogura, Jonathan Campbell, Nobuya Inagaki, Daisuke Yabe

Journal: Science advences

PubMed ID: 42853932

Doi: 10.1126/sciadv.aeh4948