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Molecular basis of the hepatobiliary tropism of typhoid toxin promoting Salmonella pathogenicity

Authors: Hwa Young Kim, Gi Young Lee, Andrew J Thompson, Ryan McBride, Dah-Jiun Fu, James C Paulson, Jeongmin Song

Journal: SCIENCE ADVANCES

PubMed ID: 40479051

Doi: 10.1126/sciadv.adt2040

Products & Services: Catalog Antibodies

ATP13A1 engages SEC61 to facilitate substrate-specific translocation

Authors: Xiaoyan Yang, Yi Li, Chengxi Yang, Tingting Li, Zhiyu Fang, Zhigang Feng, Jun Liao, Yan Zou

Journal: SCIENCE ADVANCES

PubMed ID: 40498833

Doi: 10.1126/sciadv.adt1346

Products & Services: Protein and Antibody Isolation

HIV-1 binds dynein directly to hijack microtubule transport machinery

Authors: Somayesadat Badieyan, Drew Lichon, Sevnur Komurlu Keceli, Michael P Andreas, John P Gillies, Wang Peng, Jiong Shi, Morgan E DeSantis, Christopher R Aiken, Till Böcking, Tobias W Giessen, Edward M Campbell, Michael A Cianfrocco

Journal: SCIENCE ADVANCES

PubMed ID: 40532013

Doi: 10.1126/sciadv.adn6796

LPS-enriched interaction drives spectrum conversion in antimicrobial peptides: Design and optimization of AA16 derivatives for targeting gram-negative bacteria

Authors: Wanyang Xiao, Ruize Sun, Jietao Lou, Yanyan Xu, Xiaokun Li, Kaiyun Xin, Weijie Lu, Chenhui Sun, Tianbao Chen, Yitian Gao, Di Wu

Journal: Eur J Med Chem

PubMed ID: 40048797

Doi: 10.1016/j.ejmech.2025.117462

Products & Services: Peptide Synthesis

Chondrocyte fatty acid oxidation drives osteoarthritis via SOX9 degradation and epigenetic regulation

Authors: Zixuan Mei, Kamuran Yilamu, Weiyu Ni, Panyang Shen, Nan Pan, Huasen Chen, Yingfeng Su, Lei Guo, Qunan Sun, Zhaomei Li, Dongdong Huang, Xiangqian Fang, Shunwu Fan, Haitao Zhang, Shuying Shen

Journal: nature COMMUNICATION

PubMed ID: 40425566

Doi: 10.1038/s41467-025-60037-4

Products & Services: Catalog Antibodies Protein and Antibody Isolation

MechanismsofaureobasidinA inhibition and drug resistance in a fungal IPC synthase complex

Authors: Xinyue Wu , Xin Gong , Tian Xie

Journal: nature COMMUNICATION

PubMed ID: 40442105

Doi: doi.org/10.1038/s41467-025-60423-y

Products & Services: Protein and Antibody Isolation

DNA-Engineered Modular Nanovaccines Featuring Precise Topology for Enhanced Immunogenicity

Authors: Yanfei Qu, Dawei Wang, Yunlong Zhang, Fengyun Shen, Binghui Xia, Qin Xu, Qisheng Wang, Huating Kong, Ying Zhu, Lihua Wang, Itamar Willner, Xiurong Yang, Chunhai Fan, Lele Sun

Journal: ADVANCED MATERIALS

PubMed ID: 40371439

Doi: 10.1002/adma.202500577

Products & Services: Protein and Antibody Reagents

Deep Proteomic Profiling of the Intra-Golgi Trafficking Intermediates

Authors: Farhana Taher Sumya , Walter S Aragon-Ramirez , Vladimir V Lupashin

Journal: Molecular biology of the cell

PubMed ID: 40397568

Doi: 10.1091/mbc.E24-12-0556

Products & Services: Gene Synthesis

Programmatically activated DNA hydrogel microcapsules for precision therapy in inflammatory bowel disease

Authors: Peifen Lu, Hongxiu Yuan, Gang Wang, Yixi Dong, Runyu Zhao, Jia Man, Jianwei Jiao, Zhaoyin Wang, Jin Jiao