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Regulating the N-oxidation selectivity of P450BM3 monooxygenases for N-heterocycles through computer-assisted structure-guided design
Authors: Liu Yang, Zhongji Pu, Jianping Wu, Xiaofeng Liu, Zhe Wang, Haoran Yu, Liuwei Wang, Yan Meng, Gang Xu, Lirong Yang, Wenlong Zheng
Journal: Nature Communications
PubMed ID: 40659637
Doi: 10.1038/s41467-025-61773-3
Products & Services: Protein Electrophoresis and Western   
Localized Delivery of the mRNAs Encoding CD47 Inhibitor and Interleukins 12, 15, and 21 Elicits Robust Antitumor Immunity
Authors: Tao Jiang, Shuaiyang Jing, Haojun Li, Bao Xiao, Jiahui Jin, Xiu Sun, Juan Wang, Jing Liang, Tongze Cai, Huili Hu, Meilan Wei, Xuanrui Zhong, Yang Ji, Peng George Wang, Jianlong Zhou
Journal: Advanced Science
PubMed ID: 40652522
Doi: 10.1002/advs.202417205
Products & Services: PCR Cloning and Subcloning   
Divergent Delivery and Expression Kinetics of Lipid and Polymeric Nanoparticles across mRNA Modalities
Authors: Irafasha C Casmil, Josh J Friesen, Nuthan V Bathula, Anneke Strumpel, Chia Hao Ho, Ilana Guez, Kristen Y S Kong, Andrew J Varley, Shigeki J Miyake-Stoner, Parinaz Aliahmad, Nathaniel S Wang, Andrew J Geall, Anna K Blakney
Journal: Advanced Science
PubMed ID: 40650657
Doi: 10.1002/advs.202508907
Products & Services: Circular RNA synthesis   
Single-dose avian influenza A(H5N1) Clade 2.3.4.4b hemagglutinin-Matrix-M® nanoparticle vaccine induces neutralizing responses in nonhuman primates
Authors: Nita Patel, Asma Rehman, Jessica F Trost, Rhonda Flores, Zach Longacre, Mimi Guebre-Xabier, Haixia Zhou, Bin Zhou, Kelsey Jacobson, Desheng Jiang, Xiaoyun Bai, Rafia Khatoon, Thomas Kort, James Norton, M Madhangi, Melinda Hersey, Ann M Greene, Filip Dubovsky, Gale Smith
Journal: Nature Communications
PubMed ID: 40681543
Doi: 10.1038/s41467-025-61964-y
Products & Services: Gene Synthesis   
Potentiating the Efficacy of mRNA Vaccines through NIR-II Imaging-Guided Precise Vaccination
Authors: Mengfei Li, Xue Zheng, Xinyang Yu, Shaolong Qi, Shoujun Zhu, Guocan Yu, Songling Zhang
Journal: Advanced Science
PubMed ID: 40681479
Doi: 10.1002/advs.202413014
Products & Services: Peptide Synthesis   
API5 Phosphorylation Promotes Antiviral Immunity by Inhibiting Degradation of Cytosolic RNA Sensor RLRs
Authors: Tingjuan Deng, Jianan Xu, Linglong Qin, Xingbo Wang, Chenhe Lu, Yanming Huang, Da Liu, Yan Yan, Weiren Dong, Pinglong Xu, Jiyong Zhou
Journal: Advanced Science
PubMed ID: 40641422
Doi: 10.1002/advs.202505479
Products & Services: Protein and Antibody Isolation   
Regulation of inflammatory responses by pH-dependent transcriptional condensates
Authors: Zhongyang Wu, Scott D Pope, Nasiha S Ahmed, Diana L Leung, Yu Hong, Stephanie Hajjar, Cathleen Krabak, Zhe Zhong, Krishnan Raghunathan, Qiuyu Yue, Diya M Anand, Elizabeth B Kopp, Daniel Okin, Weiyi Ma, Ivan Zanoni, Jonathan C Kagan, Jay R Thiagarajah, Diana C Hargreaves, Ruslan Medzhitov, Xu Zhou
Journal: Cell
PubMed ID: 40680734
Doi: 10.1016/j.cell.2025.06.033
Products & Services: Gene Synthesis   
Structures of the measles virus polymerase complex with non-nucleoside inhibitors and mechanism of inhibition
Authors: Yiru Wang, Lixia Zhao, Yi Zhang, Xiuxia Gao, Yannan Wang, Wenping Shi, Roger D Kornberg, Heqiao Zhang
Journal: Cell
PubMed ID: 40628260
Doi: 10.1016/j.cell.2025.06.017
Products & Services: Codon Optimization   
Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics
Authors: M Alejandra Tortorici, Annette Choi, Cecily A Gibson, Jimin Lee, Jack T Brown, Cameron Stewart, Anshu Joshi, Sheri Harari, Isabelle Willoughby, Catherine Treichel, Elizabeth M Leaf, Jesse D Bloom, Neil P King, Christine Tait-Burkard, Gary R Whittaker, David Veesler
Journal: Nature
PubMed ID: 40634609
Doi: 10.1038/s41586-025-09155-z
Products & Services: Gene Synthesis   
Biohybrid-based pyroelectric bio-denitrification driven by temperature fluctuations
Authors: Jie Ye, Shuhui Wang, Chaohui Yang, Zhenhao Zuo, Wenzhi Gu, Baogang Zhang, Shungui Zhou
Journal: Nature Communications
PubMed ID: 40595581
Doi: 10.1038/s41467-025-60908-w
Products & Services: Protein Electrophoresis and Western   
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