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SmallTalk: a novel small-sized fusion tag for peptide expression and purification

Authors: Atika Tariq, Nestor G Casillas-Vega, Alma Gomez-Loredo, Xristo Zarate

Journal: FEBS Open Bio

PubMed ID: 41220226

Doi: 10.1002/2211-5463.70147

Products & Services: Gene Synthesis

Structural insights into antagonist recognition by the vasopressin V2 receptor

Authors: Tianwei Zhang, Hongli Liu, Chongzhao You, Yixiao Zhang, Youwei Xu, Benxun Pan, Canrong Wu, Sanshan Jin, Yu-Ling Yin, Kai Wu, Yue Chen, Hong Sun, Yuan Si, Yangxia Tan, Wanchao Yin, H Eric Xu, Dong Guo, Yi Jiang

Journal: Nature Communications

PubMed ID: 41188237

Doi: 10.1038/s41467-025-64735-x

Products & Services: Protein and Antibody Isolation

GSH-activable and cytolytic iPep-coupled immune nanoagonist for cancer synergetic therapy

Authors: Shuangshuang Ji, Xiangxiang Xu, Ang Li, Hanjie Liu, Jiang Zhu, Hao Fei

Journal: Biomaterials

PubMed ID: 40373515

Doi: 10.1016/j.biomaterials.2025.123402

Products & Services: Peptide Synthesis

De N ovo -Designed Miniprotein Inhibits the Enzymatic Activity of the SARS-CoV 2 Main Protease

Authors: Tayn E. Lima; Emerson G. Moreira; Danilo F. Co lho; Carlos H. B. Cruz; Rafael Dhalia; Bruno H. S. Leite; L cya S. Xavier; Marta Perez Illana; Gabriel L. Wallau; Isabelle F. T. Viana; Roberto D. Lins

Journal: Journal of chemical information and modeling

PubMed ID: 41060276

Doi: 10.1021/acs.jcim.5c01708

The Sobering Sting: Oleoyl Serotonin Is a Novel Stephanoconus Snail Venom-Derived Antagonist of Cannabinoid Receptors That Counteracts Learning and Memory Deficits

Authors: Dongchen An; Guilherme Salgado Carrazoni; Ben-Hur Souto das Neves; Rudi D Hooge; Steve Peigneur; Jan Tytgat

Journal: Biomedicines

PubMed ID: 38398056

Doi: 10.3390/biomedicines12020454

Products & Services: Custom Vector Construction

In vitro characterization of the catalytic domain of human histone deacetylase 5

Authors: Christian Mammen; Fenja M. Hornung; Christian Anzenhofer; Julia Schumacher; Jens Reiners; Jingyu Li; Flaminia Mazzone; Florestan L. Bilsing; Matthias U. Kassack; Thomas Kurz; Sander H. J. Smits

Journal: Scientific REPORTS

PubMed ID: 41760657

Doi: 10.1038/s41598-026-37633-5

Torsional Twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains

Authors: Monica Rosas-Lemus; George Minasov; Joseph S. Brunzelle; Taha Y. Taha; Sofia Lemak; Shaohui Yin; Ludmilla Shuvalova; Julia Rosecrans; Kanika Khanna; H Steven Seifert; Alexei Savchenko; Peter J. Stogios; Melanie Ott; Karla J. F. Satchell

Journal: biorxiv

PubMed ID: 39185168

Doi: 10.1101/2024.08.13.607777

Enabling Open Machine Learning of Deoxyribonucleic Acid-Encoded Library Selections to Accelerate the Discovery of Small Molecule Protein Binders

Authors: James Wellnitz; Shabbir Ahmad; Nabin Bagale; Xuemin Cheng; Jermiah Joseph; Hong Zeng; Albina Bolotokova; Aiping Dong; Shaghayegh Reza; Pegah Ghiabi; Elisa Gibson; Guiping Tu; Xianyang Li; Jian Liu; Dengfeng Dou; Jin Li; Timothy L. Foley; Anthony R. Harris; Jacquelyn L. Klug-McLeod; Jisun Lee; Zsofia Lengyel-Zhand; Justin I. Montgomery; Sylvie Sakata; Jinzhi Zhang; Hongyao Zhu; Dafydd R. Owen; Rachel J. Harding; Aled M. Edwards; Benjamin Haibe-Kains; Levon Halabelian; Alexander Tropsha; Rafael M. Cou ago

Journal: Journal of Medicinal Chemistry

PubMed ID: 41047897

Doi: 10.1021/acs.jmedchem.5c01972

Products & Services: Protein and Antibody Isolation

Insights into next generation sequencing guided antibody selection strategies

Authors: M. Frank Erasmus; Fortunato Ferrara; Sara D Angelo; Laura Spector; Camila Leal-Lopes; Andr A. Teixeira; Jesper S rensen; Suhani Nagpal; Kathryn Perea-Schmittle; Alok Choudhary; William Honnen; David Calianese; Luis Antonio Rodriguez Carnero; Simon Cocklin; Victor Greiff; Abraham Pinter; Andrew R. M. Bradbury

Journal: Scientific REPORTS

PubMed ID: 37884618

Doi: 10.1038/s41598-023-45538-w

Products & Services: Catalog Antibodies

Rabies virus-vectored Lyme disease vaccine provides long-term protection against tick-transmitted Borrelia burgdorferi

Authors: Shantel Rios; Bibek Bhattachan; Christoph Wirblich; Anisha Chandwani; Kruthi Vavilikolanu; Jacob F. Myers; Chrysoula Kitsou; Utpal Pal; Matthias J. Schnell

Journal: npj Vaccines

PubMed ID: 41233361

Doi: 10.1038/s41541-025-01294-8